Key Benefits of the Acid Phosphatase Reagent
Suitable for use on a range of analysers
The Randox Acid Phosphatase Reagent is suitable for use on a number of third party analysers including Abbott, Olympus and Hitachi. To enquire about an Instrument Specific Application (ISA), please click the Contact Us button below.
The Randox methodology has been compared with other commercially available methods and the Randox AP assay showed excellent correlation coefficient of 0.99
The working stability of the Randox AP reagent is 5 days when stored at +2 – +8⁰C or 24 hours when stored at +15 – +25⁰C
Other Features of the Acid Phosphatase Reagent
- Kinetic Fast Red Colorimetric Methodology
- Lyophilised reagents
- Working reagent stable for 5 days at +2 – +8⁰C or for 24 hours at +15 – +25⁰C
- Measuring ranges:
- Total acid phosphatase (TAP): 2.5 – 93.9 U/l
- Non-prostatic acid phosphatase (NPAP): 2.1 – 80.2 U/l
- Suitable for the detection of both total AP and non-prostatic AP for convenience
What is the Acid Phosphatase assay used for?
Acid Phosphatase is a type of enzyme which is used to free attached phosphate groups from other molecules under acidic conditions. Human AP can be found in many tissues including; platelets, red blood cells, the liver, spleen, kidneys, intestines and bone marrow with the postpuberteral prostatic epithelial cell containing a uniquely high concentration of AP.
Human acid phosphatase can usually be found in low concentrations within the body and can usually be detected in the bloodstream. However, the discovery that prostatic carcinoma cells often retain a high concentration of AP characteristic of the normal postpubertal gland led to the recognition of the first clinically useful tumor marker. Therefore, the acid phosphatase assay is used within the clinical chemistry industry as a clinical biomarker of disease.