Alpha-1-Acid Glycoprotein (AGP) Reagent

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Alpha-1-Acid Glycoprotein

Key Benefits the Randox Alpha-1-Acid Glycoprotein reagent

Wide measuring range

The healthy range of alpha-1-acid glycoprotein is 50 – 120 mg/dl.  The Randox Alpha-1-Glycoprotein reagent can comfortably detect levels outside of this range with a measuring range of 24.6 – 453 mg/dl.

Excellent stability

Stable to expiry when stored at +2 to + 8°C

Excellent correlation with standard methods

The Randox methodology was compared against other commercially available methods and the Randox Alpha-1-Glycoprotein assay showed a correlation coefficient of r=0.99

Other Features of the Alpha-1-Acid Glycoprotein reagent

  • Immunoturbidimetric
  • Liquid ready-to-use reagents
  • Stable to expiry when stored at +2 to +8°C
  • Measuring range 24.6 – 453 mg/dl
Cat NoSizeAnalyserEasy Read
Easy Fit
 
AG2472R1 3 x 16ml
R2 3 x 5ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is Alpha-I-Acid Glycoprotein assay used for?

What is Alpha-1-Acid Glycoprotein?

Alpha-1-Acid Glycoprotein (AGP), also known as Orosomucoid, is an acute phase protein found in human serum. AGP is mainly biosynthesised in the liver and is secreted into the blood. The heart, stomach and lungs also have the ability to synthesise and secrete AGP. The function of AGP includes; the inhibition of platelet aggression, modulation of lymphocyte proliferation, and is to act as a carrier of basic drugs, steroids, and protease inhibitors.  AGP concentration levels can increase in response to infectious and inflammatory conditions, however concentration levels can decrease in response to nephrotic syndrome, pregnancy or oestrogen therapy.

What is the Alpha-1-Acid Glycoprotein assay used for?

Alpha-1-Acid Glycoprotein is primarily used for monitoring tumor recurrence.  It is a useful protein to monitor alongside Haptoglobin, where levels of both, levels of AGP and Haptoglobin should rise simultaneously.  For more information on Haptoglobin, please click here [external link]. Normalising the concentration levels of AGP during antineoplastic therapy correlates with a significantly prolonged relapse-free survival in lung cancer patients.

The Randox Alpha-1-Glycoprotein immunoturbidimetric assay is used for the quantitative in vitro determination of AGP in human serum and plasma.

Specific Protein Panel

For more information or to view more reagents within the specific protein panel, please click here.

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