Alanine Transaminase (ALT)

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Key Benefits

Wide measuring range

With a measuring range of 9.7-603 U/L, it will comfortably detect levels outside of the healthy range of 7-56 U/L

Excellent stability

Stable to expiry when stored at 2-8°C

Suitable for use on a range of analysers

Including Abbott, Olympus, Cobas and Hitachi. For full list, please see below.

Randox ALT-IFCC method

Features
  • IFCC method
  • Liquid and lyophilised reagents available
  • Stable to expiry when stored at 2-8°C
  • Measuring range 7.61 – 1161 U/l
Cat NoSizeAnalyserEasy Read
Easy Fit
 
(L) Indicates liquid option
AL120020 x 2mlGeneral Use--
AL120510 x 10mlGeneral Use--
AL12685 x 20mlGeneral Use--
AL23605 x 100mlGeneral Use--
AL2808240TSiemens Dimension

AL3801R1 6 x 51ml
R2 6 x 14ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


AL38756 x 21mlRX Daytona/Imola
Hitachi 717/911/912/704/902


AL7904R1 7 x 50ml (L)
R2 2 x 44ml
Hitachi 717/911/912/704/902
RX Daytona/Imola


AL7930R1 7 x 100ml
R2 3 x 60ml
Hitachi 717/911/912/704/902
RX Daytona/Imola


AL8006R1 6 x 68ml (L)
R2 6 x 20ml (Mod.)
RX Suzuka
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








AL8304R1 4 x 20ml (L)
R2 4 x 7ml (Mod.)
RX Daytona +/Monaco
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

Randox ALT-Colorimetric

Cat NoSizeAnalyserEasy Read
Easy Fit
 
(S) Indicates standard included in kit
AL1002 x 100mlGeneral Use--
AL1462 x 100ml (S)General Use--

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is ALT assay used for?

ALT belongs to a group of enzymes called aminotransferases. The enzyme ALT been found to be in highest concentrations in the liver, with decreasing concentrations found in the kidneys, heart, skeletal muscle, pancreas, spleen and lung tissue respectively.

ALT measurements are used in the diagnosis and treatment of certain liver diseases (e.g. viral hepatitis and cirrhosis) and heart diseases.

It is often tested in combination with AST as part of a liver panel with ALT levels being higher in most types of liver disease.

  • Mula-Abed, W-A. S. and Hanna, B.E. Measurement of serum fructosamine as an index of glycated protein in patients with nephrotic syndrome and chronic liver diseases. Bahrain Medical Bulletin 2001, 23(4)
  • Busek, S.U., et al. Hepatitis C and Hepatitis B Virus Infection in Different Hemodyalisis Units in Belo Horizonte, Minas Gerais, Brazil. Mem. Inst. Oswaldo Cruz, 2002, 97(6): 775-778
  • Oyejide, O.O. and Olushola, L. Hepatoprotective and antioxidant properties of extract of Carmellia sinensis (black tea) in rats. African Journal of Biotechnology 2005, 4(11): 1432-1438.
  • Saad, S.Y. et al. Cardiotoxic effects of arsenic trioxide/imatinib mesilate combination in rats. J. Pharm. Pharmacol. 2006, 58(4): 567-573
  • Noori, S., et al. Biochemical effectiveness of cocoa powder on electrolytes homeostasis, liver and cardiac specific enzymes and renal function. Pakistan Journal of Nutrition 2009, 8(6): 882-886
  • Suanarunsawat, T. et al. Antioxidant activity and lipid-lowering effect of essential oils extracted from Ocimum sanctum L. leaves in rats fed with high cholesterol diet. J. Clin. Biochem. Nutr. 2010, 46(1): 52-59
  • Awe, S. and Olayinka E.T. Effect of cashew wine on histology and enzyme activities of rat liver. J. Toxicol. Environ. Health Sci. 2011, 3(2): 31-38
  • Iribhogbe, O.I., et al. Effects of vitamins A, C and E on liver function in pregnancy. Asian Journal of Medical Sciences. 2011, 3(1): 8-13
  • El-Abhar, H.S. and Schaalan, M.F. Topiramate-induced modulation of hepatic molecular mechanisms: an aspect for its anti-insulin resistant effect. PLoSONE. 2012, 7(5): e37757
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