The Randox Barbiturates reagent is compared against Gas Chromatography/ Mass Spectrometry (GC/MS) which is the ‘gold standard’ in drugs of abuse testing – the Barbiturates assay has a 93.3% correlation with this
Multi-analyte controls and calibrators available
These offer the opportunity to consolidate QC and may be more cost-effective
Liquid ready-to-use reagents
The Randox Barbiturates reagent comes in a liquid format which is more convenient, and can also help reduce the risk of errors occurring
- Homogeneous Enzyme Immunoassay
- Liquid ready-to-use reagents
- Stable to expiry when stored at 2-8⁰C
- Multi-analyte controls and calibrators available
- GC/MS correlation
What is Barbiturates assay used for?
Barbiturates are central nervous system depressants. They are used therapeutically as sedatives, hypnotics, and anticonvulsants. Barbiturates are almost always taken orally as capsules or tablets. The effects resemble those of intoxication with alcohol. Chronic use of Barbiturates leads to tolerance and physical dependence. Short acting Barbiturates taken at 400 mg/day for 2 to 3 months produces a clinically significant degree of physical dependence.
Withdrawal symptoms experienced during periods of drug abstinence can be severe enough to cause death. Only a small amount (less than 5%) of most Barbiturates are excreted unaltered in the urine. The detection period for the Barbiturates in the urine is 4 to 7 days.
It is because of the Barbiturate’s sedative-hypnotic properties that they are frequently abused. The assay can be used to detect abuse of it, or to monitor therapeutic treatment.