Bile Acids

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Key Benefits

Excellent linearity

The method is linear up to a concentration of 150 µmol/l. In the event of a rerun, the linearity is extended to 225 µmol/l

Exceptional correlation with standard methods

A correlation coefficient of 0.99 was obtained with another commercially available method

Convenient

With two shot ready-to-use liquid reagents, it is convenient and can also help reduce the risk of errors occurring

Other Features

  • Colorimetric
  • Liquid and lyophilised reagents available
  • Stable to expiry when stored at 2-8°C
  • Measuring range 3.20-188 µmol/l
  • Protocols are available for a range of analysers
Cat NoSizeAnalyserEasy Read
Easy Fit
 
(L) Indicates liquid option
BI2672R1 10 x 10ml
R2 1 x 30ml
General Use--
BI3863R1 2 x 18ml (L)
R2 2 x 8ml (5th generation)
RX Daytona/Imola
Hitachi 717/911/912/704/902


BI7982R1 6 x 50ml (L)
R2 6 x 18ml (5th generation)
Hitachi 717/911/912/704/902
RX Daytona/Imola


Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is the Bile Acids assay used for?

Fasting serum Bile Acids can be used in the diagnosis and prognosis of liver disease. Levels rise in many liver diseases, for example hepatitis and liver sclerosis. Abnormal levels in fasting patients or immediately after a meal can be used to detect liver disease and damage, impaired liver function, intestinal dysfunction and perhaps a gall bladder blockage. Bile Acid measurement may detect some forms of liver disease earlier than standard liver tests because Bile Acids levels correspond to liver function, rather than liver damage. In veterinary medicine, Bile Acid measurement is considered to be a superior indicator of liver disease.

The fifth Generation Randox Total Bile Acids assay uses liquid stable two shot reagents in an enzymatic colorimetric assay for the quantitative in vitro determination of Bile Acids in serum or EDTA Heparinized plasma. The assay incorporates a more complex enzyme cycling mechanism than previous generations to amplify the signal, improving sensitivity and precision and reducing interference in haemolytic and lipaemic samples.

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