Measurement of analytes associated with nervous system dysfunction

Neurological disorders can affect the central, somatic and autonomic nervous system. At the molecular level, many analytes have been found to be involved in the pathophysiology of this complex interacting system.

Proteins such as neuron specific enolase (NSE) are considered to be neurochemical markers of brain damage due to stroke or head injury and also appear to have predictive value for outcome after acute stroke. BDNF and GFAP among others have also been linked to Alzheimer’s disease and MS. Inflammatory processes have increasingly been shown to be implicated in the pathogenesis of cerebrovascular disease, and CRP has been identified as a predictor of future stroke risk.

• Measures up to 6 Cerebral biomarkers simultaneously
• Human serum, plasma and cerebrospinal fluid (CSF) samples
• Small sample volume, just 35 - 100μl
• Fully and semi-automated analysers
• Simple sample preparation
• Wide measuring range
• Fast throughput
• Excellent sensitivity, precision and recovery
  

Cerebral Array I

• BDNF
• hFABP
• GFAP
• IL-6

Cerebral Array II

• NSE
• NGAL
• sTNFRI
• D-dimer
• TM
• CRP