Ceruloplasmin

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Key Benefits

Wide measuring range

With a measuring range of 6.29-73.8 mg/dl, it will comfortably detect levels outside of the healthy range of 20-60 mg/dl

Exceptional correlation with standard methods

A correlation coefficient of 0.95 was obtained with another commercially available kit

Convenient

With ready-to-use liquid reagents, it is convenient and can also help reduce the risk of errors occurring

Other features

  • Immunoturbidimetric
  • Stable to expiry when stored at 2-8⁰C
  • Measuring range 6.29-73.8 mg/dl
  • Correlation coefficient of r=0.95
  • A range of fully automated applications available
Cat NoSizeAnalyserEasy Read
Easy Fit
 
CPL4017R1 2 x 13.4ml
R2 2 x 4.8ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is the Ceruloplasmin assay used for?

Ceruloplasmin is an alpha2 globulin synthesised primarily in the liver. It binds to copper in the liver and is responsible for transporting more than 90% of all copper to various tissues within the body. Ceruloplasmin has several important functions including ferroxidase activity, amine oxidase activity and superoxidase activity. It is also involved in homeostasis.

The main use of Ceruloplasmin is in the diagnosis of Wilson’s disease, a rare inherited disorder characterised by liver damage and neurological deterioration. Individuals with Wilson’s disease often have decreased levels of Ceruloplasmin which subsequently leads to a build-up of copper in the liver, brain and other organs. If left untreated, Wilson’s disease can be fatal. Early detection and treatment is therefore crucial in order to prevent permanent damage and halt disease progression.

Ceruloplasmin concentrations are elevated in:

  • Bacterial infections
  • Leukaemia
  • Hodgkin’s Disease
  • Systemic Lupus Erythematosis
  • Rheumatoid Arthritis
  • Inflammation
  • Severe Infection
  • Alzheimer’s Disease
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