CK-NAC

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Key Benefits

Exceptional correlation with standard methods

A correlation coefficient of r=0.99 was found when measured against another commercially available method

Wide measuring range

The Randox CK-NAC assay has a wide measuring range of 19.4 – 2886 U/l which will comfortably detect levels outside of the healthy limits

Excellent stability

Stable to expiry when stored at 2-8°C

Other Features

  • Liquid and lyophilised reagents available
  • Stable to expiry when stored at 2-8°C
  • Measuring range 19.4 – 2886 U/l
Cat NoSizeAnalyserEasy Read
Easy Fit
 
(L) Indicates liquid option
CK11020 x 2.5mlGeneral Use--
CK33520 x 3mlGeneral Use--
CK52210 x 10mlGeneral Use--
CK2813480T (SZASZ)Siemens Dimension

CK3812R1 4 x 20ml
R2 4 x 6ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


CK38786 x 20ml (IFCC) (L)RX Daytona/Imola
Hitachi 717/911/912/704/902


CK3892R1 4 x 16.5ml (L)
R2 4 x 6.2ml (IFCC)
RX Daytona/Imola
Hitachi 717/911/912/704/902


CK7947R1 6 x 20ml
R2 3 x 10ml
Hitachi 717/911/912/704/902
RX Daytona/Imola


CK80257 x 15mlRX Suzuka
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








CK8313R1 4 x 20ml (L)
R2 4 x 7ml
RX Daytona +/Monaco
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is CK-NAC assay used for?

Creatine Kinase (CK) is primarily found in striated muscle, brain and heart tissues. The determination of CK activity in plasma or serum provides a sensitive marker for the detection of skeletal muscle disease; and is also useful in diagnosis of myocardial infarction and cerebrovascular accidents.

The determination of CK using creatine phosphate and adenosine‑5’‑diphosphate (ADP) as substrates rather than creatine and adenosine‑5’‑triphosphate (ATP) has several advantages in test performance as it allows for a faster reaction rate resulting in greater sensitivity. Small sample volumes are used and sample blanks are not required.

The UV method used is an optimised standard method according to the recommendations of the Deutsche Gesellschaft für Klinische Chemie.

  • McNeill, A.J. Thrombolytic therapy within one hour of the onset of acute myocardial infarction. Q. J. Med. 1991, 79: 487-494
  • Huang, Z-Q., et al. Effects of N-n-butyl haloperidol iodide on rat myocardial ischemia and reperfusion injury and L-type calcium current. Acta Pharmacol. Sin 2003, 24(8): 757-763
  • Mohiti, J., et al. The significance of troponin T and CK-MB release in coronary artery bypass surgery. Indian J. Clin. Biochem.2004, 19(1): 113-117
  • Lu, H-K., et al. Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress.Eur. J. Appl. Physiol. 2006, 98: 220-226
  • Randazzo-Moura, P., et al. A Study of the Myotoxicity of Bothropstoxin-I Using Manganese in Mouse Phrenic Nerve-Diaphragm and Extensor digitorium longus Preparations. Braz. J. Morphol. Sci. 2006, 23 (2): 237-246
  • Akpanabiatu, M.I., et al. Effects of interaction of vitamin A and Rauwolfia vomitoria root bark extract on marker enzymes of cardiac diseases. Indian Journal of Clinical Biochemistry. 2009, 24(3): 241-244
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