Lithium

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Key Benefits

Excellent precision

The Lithium assay showed a precision of less than 5% CV

Exceptional correlation

The Lithium assay showed a correlation of r=1.00 against another commercially available method

Limited interference

From Bilirubin, Haemoglobin, Intralipid® and Triglycerides

Randox Lithium (Colorimetric)

  • Colorimetric method
  • Liquid ready-to-use reagents
  • Stable to expiry at 2-8°C
  • Measuring range 0.259-2.99 mmol/L
Cat NoSizeAnalyserEasy Read
Easy Fit
 
LM4005R1 2 x 18.3ml
R2 2 x 6.5ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


LM8053R1 2 x 18.3ml
R2 2 x 6.5ml
RX Suzuka
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is Lithium assay used for?

Lithium, administered as Lithium carbonate, is used for the treatment of the manic phase of affective disorders, mania, and manic-depressive illness. It acts by enhancing reuptake of neurotransmitters, thereby reducing their concentration in the neuronal junction. This produces a sedating effect on the central nervous system. It is completely absorbed by the gastro-intestinal tract and peak serum levels occur 2 to 4 hours after an oral dose. The half-life in serum is 48 to 72 hours and is cleared through the kidneys. Reduced renal function can prolong clearance time.

Early symptoms of intoxification include apathy, sluggishness, drowsiness, lethargy, speech difficulties, irregular tremors, myoclonic twitchings, muscle weakness and ataxia. Levels higher than 1.5 mmol/l (12 hrs after a dose) indicate a significant risk of intoxification. Serum lithium concentrations are carried out essentially to ensure compliance and to avoid toxicity.

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