The Prothrombin Time assay showed a correlation coefficient of 0.98 against another commercially available method
Dedicated coagulation controls available
Specially designed for accurate quality control
The Prothrombin Time assay has a precision of less than 3% CV
Randox Prothrombin Time (PT) (Coagulation)
- Coagulation method
- Liquid ready-to-use reagents
- Stable to expiry date when stored at 2-8⁰C
What is Prothrombin Time (PT) assay used for?
The Prothrombin time test as originally devised by Quick(1 ,2) has been widely used as a pre-surgical screen for assessing certain coagulation factors and monitoring of oral anticoagulation therapy (coumadin, warfarin). Tissue Thromboplastin, in the presence of calcium, is an activator, which initiates the extrinsic pathway of coagulation, which includes plasma coagulation factors VII, X, V, Prothrombin and Fibrinogen. During oral anticoagulant therapy most of the Vitamin K dependent factors such as II, VII, IX, X, Protein C and Protein S are depressed. This also occurs during deficiencies of clotting factor activity which may be hereditary or acquired.