Respiratory Multiplex Array

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Most people will develop an acute respiratory tract infection (RTI) every year. ¹ Children bear the brunt of RTI illness, with infants and pre-school children in developed countries experiencing a mean of 6-10 viral infections annually, and school-age children and adolescents experiencing 3-5 illnesses annually. ²

Often, antibiotics are prescribed, however, using antibiotics can cause resistance among respiratory pathogens in individuals and in recent years an epidemic increase in antibiotic-resistant Streptococcus pneumoniae has been observed, prompting the need to decrease excess or inappropriate antibiotic use. ³

Multiplex Array simultaneously detects 21 viral and bacterial pathogens from the upper and lower respiratory tract. The array provides clinicians with a comprehensive infection profile for the patient enabling rapid and accurate diagnosis without the need for secondary or confirmatory testing to inform clinical treatment decisions. Identifying the infection correctly first time will reduce the misuse of antibiotics and improve their targeted use. Time to treatment is also reduced and unnecessary hospital stays are avoided.

Respiratory Multiplex Array detects

Viral Pathogens
  • Influenza A
  • Influenza B
  • Human respiratory syncytial virus A
  • Human respiratory syncytial virus B
  • Human parainfluenza virus 1
  • Human parainfluenza virus 2
  • Human parainfluenza virus 3
  • Human parainfluenza virus 4
  • Human coronavirus 229E/NL63
  • Human coronavirus OC43/HKU1
  • Human rhinovirus A/B/C
  • Human enterovirus A/B/C
  • Human adenovirus A/B/C/D/E
  • Human bocavirus 1/2/3
Bacterial Pathogens
  • Chlamydophila pneumoniae
  • Legionella pneumophila
  • Haemophilus influenzae
  • Bordetella pertussis
  • Streptococcus pneumoniae
  • Moraxella catarrhalis
  • Mycoplasma pneumoniae

Key Benefits

  • Simultaneously detects 21 bacterial and viral pathogens from the upper and lower respiratory tract
  • Enables identification of secondary or multiple infections
  • Rapid turnaround time of six hours
  • Reduced sample requirements and multiple sample types for patient comfort
  • May prevent the spread of infection and reduce antibiotic misuse
References
  • National Institute for Health and Care Excellence. Respiratory tract infections – antibiotic prescribing. Prescribing of antibiotics for self-limiting respiratory tract infections in adults and children in primary care. July 2008. Online. Available at: www.nice.org.uk. Last accessed 25 July 2014.
  • Pavia, A.T. Viral Infections of the Lower Respiratory Tract: Old Viruses, New Viruses, and the Role of Diagnosis. Clinical Infectious Diseases. 2011:52 (Suppl 4) S284-289.
  • Gonzales R, Bartlett JG, Besser RE, Cooper RJ, Hickner JM, Hoffman JR, et al. Principles of Appropriate Antibiotic Use for Treatment of Acute Respiratory Tract Infections in Adults: Background, Specific Aims, and Methods. Ann Intern Med. 2001;134:479-486.
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