World Heart Day 2017 – Randox Reagents

Home - World Heart Day 2017 – Randox Reagents

Join us as we celebrate World Heart Day on the 29th of September 2017. Randox Reagents aim to make a difference around the world and inspire millions to be heart healthy through offering a wide range of cutting edge cardiology and lipid reagents.

Cardiovascular disease (CVD) is responsible for 17.5million deaths per year worldwide, making it the leading cause of death (WHO, 2015). This figure is predicted to rise to 23.6million by 2030, emphasising the need for further risk assessment biomarkers to be taken into account in the assessment of CVD.

Some of our most unique cardiac assessment reagents include:

HDL3

HDL3 is our most recent addition to our cardiology testing panel. HDL3 is a sub-fraction of the HDL molecule, and enhances risk profiling of CVD due to its strong correlation with MI; elevated levels of HDL3 particles reflect abnormally increased triglyceride content of the HDL particle. This means that whilst a patient may have high levels of HDL, they may also have elevated levels of HDL3 which essentially renders the potentially potent protection factor of HDL as a cholesterol scavenger as almost useless.

Randox offers an automated HDL3 assay for the quantitative determination of HDL3 cholesterol in human serum or plasma. For more information, click here.

sLDL

sLDL is a subtype of LDL Cholesterol. It is more atherogenic due to its small size which makes it more susceptible to oxidation, and enables it to more readily permeate the inner arterial walls, causing damage and destruction. As such, the measurement of sLDL is extremely valuable as a vital risk marker of MI; in fact, elevated levels of sLDL are associated with a three-fold increased risk of MI.

Randox offers an automated sLDL assay with a wide measuring range of 0.189-22.2 mmol/l; therefore it will comfortably detect levels outside of the healthy limit of 4.90 mmol/l, ensuring a worthy addition for true assessment of CVD risk. For more information, click here.

Lp(a)

Lp(a) offers an excellent addition to the lipids profile, and should be considered due to its role in the assessment of genetically inherited risks of CVD. As genetically determined, Lp(a) remains fairly constant and is unaffected by lifestyle changes and some treatments. Elevated levels are associated with premature development of atherosclerosis and CVD, and are independent of other lipids. Testing for elevated levels is recommended for patients with a family history of premature CVD or elevated Lp(a), and for patients who have developed CVD at a young age.

Randox Lp(a) offers superior methodology, as it contains a very high density of isoform-insensitive antibodies and detection reagent. There is a five point calibrator available which takes into account the heterogeneity of the Lp(a) molecule for each of the levels, which results in excellent commutability of the calibrator with patient samples. For more information, click here.

 

You can download our cardiology & lipid testing brochure for a full list of our specialised reagents!

For more information, please contact us at reagents@randox.com




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