What Do You Know about Dehydration?

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What Do You Know about Dehydration?

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02 August 2019

What do you know about Dehydration?

Dehydration: Do you know the signs?

Dry mouth with thick saliva, headaches, feeling sleepy or irritable, weakness, dizziness made worse when you are standing… sounds like a hangover, right? These are actually all symptoms of early to mild dehydration.

While not a hangover, this can happen from drinking alcohol as it suppresses your production of a hormone called vasopressin. This hormone would normally tell your kidneys to reabsorb water rather than passing it along to your bladder – which explains the ten trips to the bathroom on a night out –  and also makes your hangover worse the next day. Below are a list of dehydration signs to look out for:

 

 

Early or mild dehydration include:

  • Flushed face
  • Extreme thirst or unable to drink
  • Dry, warm skin
  • Can’t pass urine or reduced amounts, dark yellow colour
  • Dizziness, made worse when you are standing
  • Feeling Weak
  • Cramping in the arms and legs
  • Sleepy or irritable
  • Headaches
  • Dry mouth with thick saliva

Moderate to severe dehydration include:

  • Heart failure
  • Low blood pressure
  • Fainting
  • Convulsions
  • Sunken dry eyes
  • Fast but weak pulse
  • Severe muscle contractions in the arms, legs or back
  • Bloated stomach
  • Skin loses its firmness and looks wrinkled
  • Rapid and deep breathing – faster than normal
  • Lack of elasticity of the skin

Are you at risk?

While anyone can become dehydrated, there are certain groups that are particularly at risk such as infants, older people, diabetics and athletes. But what can you do to prevent dehydration? Drink plenty of fluids. Water is the best fluid to drink when dehydrated but also having a non-fizzy, low sugar sports drink will help to replace electrolytes that have been lost. These are minerals the body needs such as chloride, calcium, magnesium, sodium and potassium. Long term dehydration can have serious effects on your health.

 

Randox Health: What We Do

Randox Health packages go beyond a health check. We have the world’s most comprehensive full-body health programmes available on the market today, thanks to Randox Biochips which enable hundreds of individual tests to be carried out from one sample and giving you truly unrivalled knowledge about your health and wellbeing both now and in the future. Our goal is to help you extend your life. Your health matters to us and, above all, we are committed to improving healthcare worldwide by identifying and preventing illness at the earliest possible stage.

 

How we can help you? 

Identifying the very first signs and risks of disease can help prevent health problems that may be on the horizon. Randox Health aim to do this before the appearance of unpleasant symptoms or illness. Prevention is always better than cure. Long-term mild dehydration may have caused damage to your health and our packages tests for up to 350 different biomarkers. Read about our packages here, or contact a member of our team for more information!

Want to know more?

Contact us or visit our Randox Health page to view more.

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H-FABP for Acute Kidney Injury Testing Revealed by Randox

2 August 2019

H-FABP for Acute Kidney Injury Testing

Revealed by Randox

A new testing application for the biomarker Heart-Type Fatty Acid-Binding Protein (H-FABP) has been announced by global diagnostics company Randox Laboratories.

Whilst H-FABP is most commonly recognized as an early biomarker of myocardial infarction, the assay’s clinical utility in cardiac surgery associated acute kidney injury (CSA-AKI) is notable. Studies have shown that patients who developed AKI following cardiac surgery had elevated levels of H-FABP both pre-and postoperatively compared to the patients who did not.

 

Susan Hammond, Randox Product Specialist, explained the new application for H-FABP;

“Cardiac surgery-associated acute kidney injury (CSA-AKI) is a well-recognized postoperative complication of cardiac surgery and is the second most common cause of AKI in the intensive care unit (ICU) – occurring in up to 30% of patients.

“Several AKI studies exist focusing on the measurement of H-FABP levels before, during and after cardiac surgery, one of which found that the post-operative H-FABP levels in patients who experienced any AKI increased 8-fold. It was also noted that the levels of those with severe AKI increased 13-fold and that 10.8% of patients who died from subsequent AKI all had elevated pre-operative levels of H-FABP.

“The Randox H-FABP assay is therefore an independent marker of AKI following cardiac surgery, and can furthermore be used as a CSA-AKI risk assessment assay even in advance of the procedure.”

It has been identified that certain patient groups are more susceptible to CSA-AKI and vulnerability can depend on age, sex, pre-existing cardiac dysfunction, pre-existing chronic kidney disease (CKD), previous cardiac surgery or comorbidity.

Susan Hammond added;

“The ability to include biomarkers that aid in the risk assessment and treatment plan management of a patient is significant.  Utilizing H-FABP alongside traditional biomarkers to assess CSI-AKI risk allows the clinician to gain stronger clinical insight in how to improve patient outcomes.”

 

Key Benefits of the Randox H-FABP assay

A niche product from Randox meaning that Randox are one of the only manufacturers to offer the H-FABP assay in an automated biochemistry format

CE marked for diagnostic use

Automated assay offering a more convenient and time efficient method for H-FABP measurements compared to traditional testing

Exceptional correlation of r=0.97 when compared against other commercially available methods

Applications available detailing instrument-specific settings for the convenient use of the Randox H-FABP assay on a wide range of clinical chemistry analysers

Liquid ready-to-use format for convenience and ease-of-use

Latex enhanced immunoturbidimetric method delivering high performance compared to traditional ELISA testing

Rapid results within fourteen minutes, depending on the analyser.

Wide measuring range of 0.747 – 120ng/ml for the early detection of clinically important results

Dedicated H-FABP controls and calibrator available offering a complete testing package


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