Benefits of the Randox Homocysteine Assay
Two-part liquid ready-to-use reagent format
The Randox homocysteine assay is available in a two-part liquid ready-to-use format, limiting interference from bilirubin, haemoglobin, triglycerides and intralipid®, producing more accurate and precise results.
The Randox homocysteine assay is standardised to the NIST SRM 1955 (Homocysteine Standard Reference Material) displaying a correlation coefficient of r=0.98 when compared to industry comparative methods.
Excellent measuring range
The Randox homocysteine assay has a measuring range of 1.7 – 47.9 μmol/l for the comfortable detection of clinically important results.
Calibrator included in the kit
The Randox homocysteine kit includes the calibrator simplifying the ordering process.
Controls available offering a complete testing package.
Applications available detailing instrument-specific settings for the convenient use of the Randox homocysteine assay on a variety of clinical chemistry analysers.
Aldolase is a glycolytic enzyme responsible for catalysing the conversion of fructose 1-6-diphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate via the glycolysis metabolic pathway. Aldolase is present in all bodily cells, more commonly in the nucleus and cytoplasm. Aldolase has been identified as having three isoforms: A, B and C. Isoform A is found bound to the actin-containing filament of the cytoskeleton. By binding (reversible) to these filaments, aldolase aids in regulating cell contractions. The highest concentrations of aldolase are present in the brain, liver and muscles 1.
Elevated levels of aldolase are detected in myotonic muscular disease, including: polymyositis and progressive muscular dystrophy. Elevated aldolase levels have been observed in acute coronary syndromes 1. Aldolase has been identified as a myositis biomarker, a muscle-wasting disease resulting in reduced muscle strength and fatigue 2. Aldolase testing can be utilised as a marker in the differential diagnosis of muscle weakness as aldolase levels remain consistent where weakness is caused by neurological problems such as multiple sclerosis (MS) 3.
Want to know more?
Contact us or download the cardiology & lipid testing brochure to learn more.
Reagents Resource Hub
 Berridge BR, Van Vleet JF, Herman E. Cardiac, Vascular, and Skeletal Muscle Systems. Haschek WM, Rousseaux CG, Wallig MA (eds). Haschek and Rousseaux’s Handbook of Toxicologic Pathology, 3rd ed. Academic Press; 2013. pp. 1567-1665
 The Myositis Association. About Myositis. https://www.myositis.org/about-myositis/ (accessed 27 February 2020)
 The Myositis Association. Blood Tests. https://www.myositis.org/about-myositis/diagnosis/blood-tests/ (accessed 27 February 2020).