Key Benefits of the Randox Alanine Aminotransferase (ALT) reagent
Wide measuring range
The healthy range for ALT is 7 – 56 U/l but the Randox Alanine Aminotransferase (ALT) assay can comfortably detect levels outside of the healthy range, measuring from 4.25 – 666 U/l
ALT is stable to expiry when stored at +2 to +8°C
Suitable for use on a range of analysers
The Randox Alanine Aminotransferase (ALT) Reagent is suitable to use on a number of third party analysers Including Abbott, Olympus, Cobas and Hitachi. To enquire about an Instrument Specific Application (ISA), please click the contact us button below.
Other Features of the Alanine Aminotrabsferase (ALT) reagent
- IFCC method
- Available as liquid and lyophilised reagents
- Stable to expiry when stored at +2 to +8°C
- Wide Measuring range 4.25 – 666 U/l
What is ALT assay used for?
What is ALT?
Alanine Aminotransferase is one of the enzymes within the aminotransferases group and are among the most sensitive liver enzymes. The highest concentrations of the ALT enzyme can be in the liver, with decreasing concentrations found in the kidneys, heart, skeletal muscle, pancreas, spleen and lung tissue respectively.
What is the ALT assay used for?
ALT measurements are used in the diagnosis of hepatic damage and diseases including viral hepatitis and cirrhosis.
The normal concentration levels of ALT in the blood are low, however, when damaged, the liver releases more ALT into the blood causing the concentration levels to rise. When diagnosing for hepatic damage, the root cause of the damage can be established, such as disease, drug, or injury
The ALT test not only allows for the diagnosis of liver disease but also allows for the diagnosis of the root cause of the disease
It is often tested in combination with the aspartate aminotransferase (AST) test as part of the hepatic panel with alanine aminotransferase levels being higher in most types of liver disease. For more information on the validity and clinical utility of AST and ALT when assessing disease severity, please click here [external link].
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