An End-to-End Genomics Solution
Randox Genomics Services department is fitted with a specialised, fully equipped, state of the art testing facilities, designed and set up to fulfil a unique range of end-to-end sequencing solutions inclusive of in-house bioinformaticians and data analysts.
Our Services
Randox Laboratories is a global market leader within the in vitro diagnostics industry. Utilising a multitude of platforms, our sequencing and genotyping facility is suited to a wide range of areas of genome sequencing.
Our team of genetic scientists and bioinformaticians provide customisable sequencing and genotyping services for research, development, validation and running of different genomic tests to generate high quality data in line with modern healthcare and future disease insights.
A dedicated team of genetic scientists including automation specialists, enabling adaption to testing throughputs changes from call small projects to large scale testing.
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Huge capacity for storage and accessioning of multiple sample types with fast turnaround times.
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Specific customised project planning and validation of services, tailored to the needs of each Randox customer.
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Multiple options for variable throughput from low throughput instruments, to the largest sequencer on the market with targeted solutions in multiple areas.
Olink®
Comprehensive Proteomic Solutions Provider
As one of the first UK commercial partners of Olink® Proximity Extension Assay (PEA) technology, Randox offer scientists involved in drug development, clinical, or basic life science research, the services they need to run large-scale discovery proteomics.
Randox offer customers access to the entire Olink® protein library of~3000 protein assays for exploratory proteomics and multiomics to empower biomarker discovery through the analysis of both low and high abundance proteins (fg/mL – mg/mL) with high sensitivity.
Features & Benefits
- Covers all major biological pathways with ~3000 validated protein assays
- High sample throughput for large scale proteomic studies and research
- Minimal sample volume with just 60uL for the complete library
- Exceptional specificity in comparison to mass spec utilising PEA technology
- Compatible with a wide variety of sample types
Olink® Workflow
Next-Generation Sequencing (NGS)
Next-generation sequencing (NGS) technology offers ultra high-throughput, scalability, and speed. It can be used to determine the order of nucleotides in entire genomes or targeted regions of DNA or RNA.
Sequencing every protein coding region (approximately 21,000 genes) to identify any variants that may increase the risk of developing certain conditions or impact health/lifestyle.
Sequencing every single base in your DNA (approximately 3.2 billion) to identify any variants that may increase the risk of developing certain conditions or impact health/lifestyle..
16s rRNA gene sequencing involves the analysis of the prokaryotic 16s ribosomal RNA gene which is found in all bacteria and archaea.
Shotgun sequencing reads all the genomic DNA in the sample, rather than just one specific region. Therefore, this sequencing method provides a vast amount of genetic information as it can identify archaea, bacteria, fungi and viruses.
NGS Workflow
Genotyping
Genotyping is the process of analysing DNA to detect SNPs of interest. These SNPs are compared to reference SNPs, available from years of genetic research, to determine differences in genetic makeup.
- GSA + DTC custom content
Over 710,000 SNPs across the human genome
- GDA + Enhanced PGx
Over 1.8 million SNPs across the human genome enhanced with pharmacogenomic specific markers
Pharmacogenomics
Pharmacogenomics is the study of how a person’s DNA effects their drug response. It combines pharmacology and genomics. This is a relatively new field in science but it is expected to be the future of medicine as it focuses on personalised medicine and treating every patient individually. At Randox we use Illumina’s Infinium Global Diversity Array with Enhanced PGx microarray to test for pharmacogenomic markers. This is the most comprehensive genotyping microarray on the market for pharmacogenomic research.
Genotyping Workflow
