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Reagent | H-FABP (Cardiac)

A Superior Marker of Acute Coronary Syndrome

Cardiology & Lipid Testing Brochure

Benefits of the Randox H-FABP (Cardiac) Assay

Superior Performance

Superior method

The Randox latex enhanced immunoturbidimetric (L.E.I) method offers a more convenient, high performing and time efficient (results in 14 minutes, depending on analyser) method compared to traditional ELISA testing.

Excellent Correlation

Excellent correlation

A correlation coefficient of r=0.97 was displayed when the Randox methodology was compared against commercially available methods.

Measuring range

Wide measuring range

The Randox H-FABP assay can comfortably detect levels outside of the healthy range, measuring between 0.747 – 120ng/ml.

Liquid ready-to-use

Liquid ready-to-use assay

The Randox H-FABP assay is available in a liquid ready-to-use format for convenience and ease-of-use.

Calibrator & Controls

Dedicated calibrator and controls available

Dedicated H-FABP calibrator and controls available offering a complete testing package.

Applications available

Applications available detailing instrument-specific settings for the convenient use of the Randox H-FABP assay on a variety of clinical chemistry analysers.

H-FABP Calibrator

H-FABP Controls

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References
[1] Release of fatty acid-binding protein from isolated rat heart subjected to ischemia and reperfusion or to the calcium paradox. Glatz, J F, et al. 52, Maastricht : The Clinical Biochemist, 1988, Vol. 148.

[2] Clinical study of H-FABP for risk stratification and prognosis in patients with early cTnT-negative ACS. Liu, Yawei, et al. Beijing : Internal Journal of Clinical and Experimental Medicine, 2017. 1940-5901.

[3] Al-Dabbagh, Ihsan Hassan. Heart type fatty acid binding protein H-FABP. College of Medicine-Mosul. [Online] [Cited: November 06, 2018.] http://medicinemosul.uomosul.edu.iq/files/news/news_4087987.pdf.

[4] Supplementary Online Content: Serial Changes in Highly Sensitive Troponin I Assay and Early Diagnosis of Myocardial Infarction. Keller, T, Zeller, Tanja and Ojeda, Francisco. Hamburg : JAMA, 2011.

[5] Clinical and analytical evaluation of an immunoturbidimetric heart-type fatty acid-binding protein assay. Carless, Daniel R, et al. 1, s.l. : Scandinavian Journal of Clinical and Laboratory Investigation, 2013, Vol. 73.

[6] Misdiagnosis of Myocardial Infarction Related to Limitations of the Current Regulatory Approach to Define Clinical Decision Values for Cardiac Troponin. Wildi, Karin, et al. Trimbach : Circulation, 2015.

[7] Heart Fatty Acid Binding Protein and cardiac troponin: development of an optimal rule-out strategy for acute myocardial infarction. Young, Joanna M, et al. Christchurch : BMC Emergency Medicine, 2016.

[8] Diagnostic Performance of a Combination Biomarker Algorithm for Rule-Out of Acute Myocardial Infarction at Time of Presentation to the Emergency Department, Using Heart-Type Fatty Acid-Binding Protein and High-Sensitivity Troponin T tests. Navarro, César O, et al. Belfast : Journal of Clinical and Experimental Cardiology, 2018.

[9] Prognostic Value of a Multimarker Approach for Patients Presenting to Hospital With Acute Chest Pain. McCann, Conor J, et al. 1, Belfast : The American Journal of Cardiology, 2009, Vol. 103.

[10] Early Diagnosis of Myocardial Infarction with Sensitive Cardiac Troponin Assays. Reichlin, Tobias, et al. 9, Massachusetts : The NEW ENGLAND JOURNAL of MEDICINE, 2009 , Vol. 361.

[11] Heart-Type Fatty Acid-Binding Protein Predicts Long-Term Mortality and Re-Infarction in Consecutive Patients With Suspected Acute Coronary Syndrome Who Are Troponin-Negative. Viswanathan, Karthik, et al. 23, Leeds : Journal of the American College of Cardiology, 2010, Vol. 55. 0735-1097.

[12] Heart-type fatty acid-binding protein (H-FABP) and highly sensitive troponin T (hsTnT) as markers of myocardial injury and cardiovascular events in elective percutaneous coronary intervention (PCI). Connolly, M, et al. 1, Belfast : QJM: An International Journal of Medicine, 2017, Vol. 111.

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