Lipoprotein (a) Awareness Day 2023

Home - Lipoprotein (a) Awareness Day 2023

Randox are raising awareness for Lipoprotein(a), we want to drive awareness on tests that are available to you to decrease the risk of stroke, heart attack or other heart diseases!

Lp(a) is a risk factor for atherosclerosis and related diseases including CHD and stroke. It is increasingly recognised as the strongest known genetic risk factor for premature coronary artery disease.

Identifying any possible health conditions that would relate to early signs of stroke, heart attack or other heart diseases will allow you to make any decisions on an appropriate diet, lifestyle changes and early treatment to reduce your risk of further problems.

Benefits of the Randox Lp(a) assay

 

 WHO/IFCC Reference Material

 Dedicated Five-Point Calibrator Available

 Excellent Correlation

 Excellent Precision

 Liquid Ready-To-Use

 Available in nmol/L

Applications Available-
on Roche, Abbott, Beckman, and more.

The biggest challenge that exists surrounding Lp(a) measurement is the heterogeneity of the apo(a) isoforms, resulting in the underestimation or overestimation of Lp(a) concentrations. In immunoassays, the variable numbers of repeated KIV-2 units in Lp(a) act as multiple epitopes. This is where standardisation across calibrators is vital. Unless the calibrants do have the same range of isoforms as test samples, those with higher numbers of the KIV-2 repeat, will represent with an overestimation in Lp(a) concentrations and those with smaller numbers of the KIV-2 repeat, will represent with an underestimation. The smaller isoforms are strongly associated with higher Lp(a) concentrations. Lack of standardisation of the calibrant would result in an underestimation of Lp(a) associated CVD risk. It is important to note that an Lp(a) immunoassay employing isoform insensitive antibodies does not exist.

How can Randox help?

Randox Sales Reps are experts in their fields and are available to discuss your specific requirements. 

Simply send us an email by clicking the link below and we will get in touch!


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