Metabolic Syndrome Array from Randox Biosciences

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Metabolic Syndrome

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20 December 2019

 

Metabolic Syndrome Array from Randox Biosciences

Metabolic syndrome is a cluster of conditions that occur together, increasing your risk of heart disease, stroke and type 2 diabetes.

According to the NHS, it occurs when a person has three or more of the following measurements1:

  • Abdominal obesity (Waist circumference of greater than 40 inches in men, and greater than 35 inches in women)
  • Triglyceride level of 150 milligrams per deciliter of blood (mg/dL) or greater
  • HDL cholesterol of less than 40 mg/dL in men or less than 50 mg/dL in women
  • Systolic blood pressure (top number) of 130 millimeters of mercury (mm Hg) or greater, or diastolic blood pressure (bottom number) of 85 mm Hg or greater
  • Fasting glucose of 100 mg/dL or greater

Metabolic syndrome is a serious health condition that affects about 23 percent of adults and places them at higher risk of cardiovascular disease, diabetes, stroke and diseases related to atherosclerosis in arterial walls.The underlying causes include obesity, physical inactivity, genetic factors and aging. 3

Randox offers 10 metabolic syndrome biomarkers over 2 panels enabling multiplex testing to be performed on Randox Biochip Technology. One patient sample is required per test enabling multiple results. Biochip Technology powers the Randox Investigator, a semi-automated benchtop immunoassay analyser.

Metabolic Syndrome Array I

  • Ferritin
  • Interleukin-6 (IL-6)
  • Insulin
  • Leptin
  • Plasminogen Activator Inhibitor-1 (PAI-1)
  • Resistin
  • Tumour Necrosis Factor α (TNFα)

Metabolic Syndrome Array II

  • Adiponectin
  • C-reactive Protein (CRP)
  • Cystatin C

Key Benefits of the Metabolic Syndrome Array

 Biochip Array Technology allows multiplex testing from one patient sample

  • Applicable to fully automated and semi-automated Evidence analysers
  • Biochips are ready to use, thus saving time, labour and resources
  • Rapid turnaround time
  • Validated for both serum and plasma samples – suitable for clinical research studies
  • Small sample volume – 100μl to measure all analytes on each array
  • Excellent analytical performance
  • Multi-analyte controls and calibrators
  • Highly efficient use of valuable patient sample banks
  • No non-specific aggregation, which is associated with multi-analyte bead assays
  • Can be used in the investigation of insulin resistance, pro‑thrombotic state, abnormal body fat distribution, pro‑inflammatory state and atherogenic dyslipidaemia

Randox Biochip Technology is an intelligent chemically activated 9x9mm ceramic biochip which acts as a solid phase reaction vessel. The biochip is spotted with multiple antibodies offering multiplex testing.

The good news is that if you discover that your metabolic health is sub-optimal you can improve it through a combination of diet, exercise and lifestyle adjustments from 30 minutes of moderate to intense exercise 5-7 times a week to quitting smoking and limiting your alcohol intake.

Randox can assist your metabolic research by providing innovative diagnostic technology and tests that will continue to revolutionise the healthcare landscape and assist in academic research. This technology includes our Evidence Investigator and our Metabolic Syndrome Array I and Array II which can be used to assist you in the discovery and research of Metabolic diseases.

For more information visit Randox Biosciences or email info@randoxbiosciences.com

 References

1 https://www.nhs.uk/conditions/metabolic-syndrome/

2http://www.heart.org/en/health-topics/metabolic-syndrome/about-metabolic-syndrome

3 https://www.saga.co.uk/magazine/health-wellbeing/conditions/cardiovascular/metabolic-syndrome

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