Randox Genotyping Services | Targeted SNP Detection & Pharmacogenomics

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The Randox Genomics Services Department currently has target genotyping solutions in multiple areas. Genotyping is the process of analysing DNA to detect SNPs of interest. These SNPs are compared to reference SNPs, available from years of genetic research, to determine differences in genetic makeup.

Genotyping Advantages and Applications

Clinical Diagnostics

Determine whether resistance genes or genetic mutations in bacterial strains make it resistant to one or more drugs. Can be used to monitor variants during pandemics, identifying when new variants become dominant.

Clinical Research

Allows researchers to focus on genes, variants, and regions of interest relevant to certain diseases. Enables the study of populations not supported by standard products and can be used to create personalised drugs.

Food & Agriculture

Identify potential genes for improving breeding and management programmes. Can be used to help increase yield and improve quality.

Next Generation Sequencing (NGS) Advantages

GSA + Custom content

Over 710,000 SNPs across the human genome with additional DTC content.

GDA + Enhanced PGx

Over 1.8 million SNPs across the human genome enhanced with pharmacogenomic specific markers.

Our Technology

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Genotyping Workflow

Extraction of genomic DNA and sample QC

Amplification of DNA

Fragment, precipitate and resuspend DNA

Hybridisation of DNA

Data analysis and report

Wash, extend and stain

Image beadchip

Data analysis and report

Pharmacogenomics

Pharmacogenomics (PGx) is the study of how a person's DNA effects their drug response. This is a relatively new field in science but it is expected to be the future of medicine as it focuses on personalised medicine and treating every patient individually.

Microarray Technology for PGx

At Randox we use Illumina's Infinium Global Diversity Array with Enhanced PGx microarray to test for pharmacogenomic markers. This is the most comprehensive genotyping microarray on the market for pharmacogenomic research. The microarray features over 44,000 genome-wide PGx markers which span more than 20000 pharmacogenomic targets and gives 100% coverage of priority level A and B CPIC genes.