SARS-CoV-2 Surrogate Virus Neutralisation Assay

Competitive Inhibition of ACE2 / RBD Interaction

Simultaneous detection of neutralising SARS-CoV-2 antibodies

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    Identifies a protective immune response to SARS-CoV-2 indicating how long neutralising antibodies are present after infection
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    Fast & accurate detection with no sample preincubation step required
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    Accurately measures vaccine efficacy during clinical trials and delivers an accurate estimation of herd immunity
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    Specificity of 100% and sensitivity of 98% compared to conventional virus neutralisation test
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    Accurately detects antibodies that are capable of inhibiting virus replication and neutralising the infectivity of the virus
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    Superior method of sVNT compared to conventional gold standard methods

Randox SARS-CoV-2 Surrogate Virus Neutralisation Assay qualitatively detects total neutralizing antibodies targeting the viral spike (S) protein receptor-binding domain (RBD) in an isotype- and species-independent manner.

Intended as an aid in the identification of patients with neutralising antibodies to the SARS-CoV-2 virus which infers protective immunity and will allow stratification of at-risk groups/populations where additional booster vaccinations may be required.

Utilising patented Biochip Array Technology on the Evidence Investigator, the assay measures circulating antibodies against SARS-CoV-2 that block interaction between the S (RBD) protein with the human angiotensin-converting enzyme 2 (ACE2) cell surface receptor. The test measures the binding capability of these two proteins in the presence of the patient’s serum or plasma to identify the presence of neutralising SARS-CoV-2 antibodies.

Available Platforms

Evidence Investigator

Cost effective and efficient semi-automated multiplex testing solution

Medium to high throughput (54 samples in < 3 hours)

Limited sample volume requirement (12ul)

Suitable for clinical and research testing

Comprehensive immunoassay and molecular test menu available

Evidence Investigator

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page

Related Products

EVidence Investigator

SARS-CoV-2 RBD & NP Array

COVID-19

COVID-19 Disease Management

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