Microalbumin Assay
Reagent | Microalbumin
Powered by BiozBenefits of the Randox Microalbumin Assay
Exceptional correlation
A correlation coefficient of r=0.99 was displayed when the Randox microalbumin assay was compared to commercially available methods.
Dedicated calibrator & controls available
Dedicated calibrator and controls available offering a complete testing package.
Excellent precision
The Randox microalbumin assay displayed a precision of <4.8% CV.
Liquid ready-to-use
The Randox microalbumin assay is available in a liquid ready-to-use format for convenience and ease-of-use.
Applications available
Applications available detailing instrument-specific settings for the convenient use of the Randox microalbumin assay on a variety of clinical chemistry analsyers.
Ordering Information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| MA2426 | R1 1 x 60ml (C) (L) R2 1 x 7ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| MA3828 | R1 6 x 20ml (L) R2 3 x 8ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| MA8056 | R1 2 x 20ml (L) R2 2 x 6.6ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| MA8325 | R1 1 x 20ml (L) R2 1 x 4.6ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| MA4072 | R1 3 x 20ml (L) R2 3 x 7.5ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| MA8388 | R1 1 x 20ml (L) R2 1 x 7.8ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| MA8160 | R1 2 x 20ml (L) R2 2 x 9ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (C) Indicates calibrator included in kit (L) Indicates liquid option |
|||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
Albumin is one of the major plasma proteins and is usually present in very low concentrations in urine. Damage to the glomerular basement membrane can alter its permeability meaning albumin and other proteins usually reabsorbed and recirculated in the blood enter the urine. Sustained elevations of urinary albumin concentrations are called microalbuminuria 1.
Microalbuminuria is strongly associated with poor glycaemic control, hypertension and other diabetic complications including ischaemic heart disease, diabetic retinopathy and neuropathy. Microalbumin is an early biomarker of diabetic nephropathy, the most common complication of type 2 diabetes mellitus (T2DM) 2. Microalbuminuria is an independent predictor of progressive renal disease and cardiovascular mortality. Due to the increasing prevalence of obesity, type 2 diabetes and metabolic syndrome in children, screening for microalbuminuria seems highly relevant in the paediatric population to detect and prevent cardiovascular disease 3.
Microalbumin Calibrator
Microalbumin Control
Human Urine EQA
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Transferrin
Reagent | Transferrin
Key Benefits
Excellent precision
The Transferrin assay has a precision of less than 5% CV
Applications available
For a wide variety of clinical chemistry analysers including the RX series
Strong correlation
The Transferrin assay showed a correlation coefficient of 0.98 against another commercially available method utilising a BCR/CAP/IFCC CRM 470 international standard
Randox Transferrin (Immunoturbidmetric)
- Immunoturbidimetric method
- Liquid ready-to-use reagents
- Stable to expiry at 2-8⁰C
- Measuring range 7.60-536 mg/dl
- Applications available
| Cat No | Size | ||||
|---|---|---|---|---|---|
| TF3831 | R1 6 x 20ml (L) R2 3 x 14ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Transferrin assay used for?
Transferrin (siderophilin) is the principal iron binding and transport protein in human plasma and can bind two molecules of iron. The normal range for healthy adults is 200-400 mg/dl. Iron availability in the plasma regulates transferrin levels which increase when plasma iron is low.
Transferrin levels increase during pregnancy and oestrogen administration and correlate closely with Total Iron Binding Capacity of serum. Plasma transferrin levels are associated with a range of conditions including anaemia, iron deficiency, inflammation or malignancy, liver disease, malnutrition and protein loss.
Transferrin can also be described as a preventative antioxidant and acts by binding iron in a redox inactive form. This process is extremely important as free iron is capable of stimulating the production of harmful free radicals
Antioxidant Panel
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Total Iron Binding Capacity (TIBC)
Reagent | Total Iron Binding Capacity (TIBC)
Key Benefits
Exceptional correlation
The TIBC assay showed a correlation coefficient of 0.9 against another commercially available method
Eliminates negative bias
Traditional calculation methods using the unsaturated iron-binding capacity (UIBC) and serum iron (TIBC = UIBC + serum iron) have a significant negative bias compared with direct TIBC methods. Randox’s TIBC assay eliminates this bias
Excellent precision
The TIBC assay has a precision of less than 4% CV
Randox Total Iron Binding Capacity (TIBC) (Colorimetric)
- Colorimetric method
- Liquid ready-to-use reagents
- Eliminates negative bias
- Stable to expiry when stored at 2-8⁰C
- Minimal interferences
| Cat No | Size | ||||
|---|---|---|---|---|---|
| TI4064 | R1 4 x 9ml (L) R2 4 x 4ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| TI8065 | R1 4 x 8.7ml (L) R2 4 x 4.9ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| TI8375 | R1 4 x 10ml (L) R2 4 x 5.1ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
What is Total Iron Binding Capacity (TIBC) assay used for?
Iron is transported in the blood by the serum protein transferrin. Transferrin is normally 30% saturated, that is 30% of the iron-binding sites contain an iron atom. The total iron-binding capacity (TIBC) is the amount of iron needed to 100% saturate transferrin. TIBC reflects iron status: levels are elevated when iron levels are low; therefore it is useful in the diagnosis and monitoring of iron deficiency anaemia and iron deficiency in late pregnancy. Abnormal levels of TIBC can point towards a variety of disease states such as hereditary haemochromatosis, a common genetic disorder where iron levels are excessive, other anaemias, liver disease and malnutrition.
Antioxidant Panel
For more information or to view more reagents within the antioxidant panel, please click here
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Glutathione Reductase
Reagent | Glutathione Reductase
Key Benefits
Applications available
For a wide variety of clinical chemistry analysers
Exceptional correlation
The Glutathione Reductase assay showed a correlation of r=0.988 against another commercially available method
Excellent linearity
387 U/l, removing the need for sample dilution
Randox Glutathione Reductase (UV)
- UV method
- Lyophilised reagents
- Working reagent stable for 2 days when stored at 2-8°C
- Measuring range 9.69 – 387 U/l
Ordering Information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| GR2368 | R1 5 x 5ml R2 5 x 3ml | Enquire | Kit Insert Request | MSDS | Buy Online |
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Glutathione Reductase assay used for?
Glutathione Reductase is required for the regeneration of reduced glutathione which is important for normal cellular metabolism. This enzyme is often discussed in association with Glutathione Peroxidase, which requires reduced glutathione for activation. Glutathione Reductase is responsible for maintaining levels of reduced glutathione which has many important functions in the cell. Glutathione plays a role in protein folding and the maintenance of reduced pools of vitamin C and E. Reduced levels of this enzyme have been described in several diseases.
- Seghrouchni, I., et al. (2002) Oxidative stress parameters in type I, type II and insulin-treated type 2 diabetes mellitus; insulin treatment efficiency. Clin. Chim. Acta. 321(1-2): 89-96
- Zachwieja, J. et al. (2003) Decreased antioxidant activity in hypercholesterolemic children with nephrotic syndrome. Med. Sci. Monit., 9:CR287-291
- Malinowski, E., et al. (2004) The effect of some drugs injection to pregnant heifers on blood antioxidant status. Pol. J. Vet. Sci.,7: 91-95
- Banfi, G., et al. (2006) Plasma oxidative stress biomarkers, nitric oxide and heat shock protein 70 in trained elite soccer players.Eur. J. Appl. Physiol., 96: 483-486
- Celik, I., et al. (2006) Antioxidant and immune potential marker enzymes assessment in the various tissues of rats exposed to indolacetic acid and kinetin: A drink water study. Pesticide Biochemistry and Physiology. 86: 180-185
- Tátrai, E., et al. (2006) Redox status and expression of chemokines in the rat lungs on exposure to asbestos and asbestos substituents. Neuro. Endocrinol. Lett. 27 Suppl 2: 40-43
- Drelich, G., et al. (2007) (Article in Polish) Imbalance of oxidoreductive status in suicidal antidepressant drugs poisoning. Przegl. Lek. 64: 258-259
- Čolak, E. et al. (2008) Biomarkers of enzymatic and non-enzymatic antioxidative defense in type 2 diabetes mellitus-comparative analysis. Biochemia Medica. 18 (2): 42-51
- Perše, M., et al. (2009) Effect of high-fat mixed-lipid diet and exercise on the antioxidant system in skeletal and cardiac muscles of rats with colon carcinoma. Pharmacol. Rep. 61(5): 909-916
- Biljak, V.K.. et al. (2010) Glutathione cycle in stable chronic obstructive pulmonary disease. Cell Biochem. Funct. 28(6): 448-453
- Singh, N. et al. (2010) Adverse health effects due to arsenic exposure: Modification by dietary supplementation of jaggery in mice. Toxicol. Appl. Pharmacol. 242(3): 247-255
- Djordjevic, J., et al. (2011) Fluoxetine affects antioxidant system and promotes apoptotic signalling in Wistar rat liver. Eur. J.Pharmacol. 659(1): 61-66
- Huo, H.Z., et al. (2011) Hepatoprotective and antioxidant effects of licorice extract against CCl4-induced oxidative damage in rats. Int. J. Mol. Sci. 12: 6529-6543
- Voljč., M., et al. (2011) Evaluation of different vitamin E recommendations and bioactivity of α-tocopherol isomers in broiler nutrition by measuring oxidative stress in vivo and the oxidative stability of meat. Poult. Sci. 90(7): 1478-1488
- Dogliotti, G., et al. (2012) Natural zeolites chabazite/phillipsite/analcime increase blood levels of antioxidant enzymes. J. Clin. Biochem. Nutr. 50(3): 195-198
- Gravina, L., et al. (2012) Influence of nutrient intake on antioxidant capacity, muscle damage and white blood cell count in female soccer players. J. Int. Soc. Sports Nutr. 9(1): 32
- Hübner-Wózniak E., et al. (2012) Effect of rugby training on blood antioxidant defenses in able-bodied and spinal cord injured players. Spinal Cord 50(3): 253-256
- Herbet, M., et al. (2013) Influence of combined therapy with rosuvastatin and amitriptyline on the oxidation-reduction status in rats. Acta Poloniae Pharmaceutica. 70(5): 913-917
Diabetes Panel
For more information or to view more reagents within the diabetes panel, please click here
IgA
Reagent | IgA
Key Benefits
Excellent precision
The IgA assay showed a precision of less than 3% CV
Exceptional correlation
The assay showed a correlation of r=0.98 against another commercially available method
Interference
There is no cross reaction with IgG and IgM under the conditions of the assay. Extremely lipaemic or haemolytic samples and high levels of ionic detergents may interfere in the assay
Other features
- Immunoturbidimetric method
- Liquid ready-to-use reagents
- Stable to expiry when stored at +2⁰C to +8⁰C
| Cat No | Size | ||||
|---|---|---|---|---|---|
| IA3832 | R1 3 x 20ml (L) R2 3 x 14ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| IA8046 | R1 5 x 8.7ml (L) R2 5 x 3.9ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is IgA assay used for?
Measurement of IgA is used to diagnose diseases of the respiratory tract e.g. tuberculosis, Crohn’s disease and early cirrhosis of the liver. It is also useful in monitoring therapy of IgA myeloma and evaluating IgA immunity. IgA in colostrum and milk is important in neonatal defence against infection.
The Randox IgA assay is an immunoturbidimetric end-point method for manual use and on automated analysers. The increase in turbidity in a sample containing human IgA is measured at 340 nm. By constructing a standard curve from the absorbances of standards, the IgA concentration of a sample can be determined.
Specific Proteins Panel
For more information or to view more reagents within the specific proteins panel, please click here
Haptoglobin
Reagent | Haptoglobin
Key Benefits
Excellent traceability
Standardised to Certified Reference Material (CRM Da470k/IFCC)
Exceptional correlation
A correlation coefficient of r=0.97 was obtained against another commercially available kit
Excellent stability
Onboard reagent stability of 28 days. Calibration is only required every seven days
Other features and benefits
- Immunoturbidimetric method
- Liquid reagents
- Stable to expiry when stored at +2 to +8°C
- Fully automated applications available for a wide range of clinical chemistry analysers
Ordering information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| HP3886 | R1 1 x 12ml (L) R2a 1 x 3.2ml R2b 1 x 0.625ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| HP8151 | R1 1 x 12ml (L) R2 2 x 4.2ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Haptoglobin assay used for?
Haptoglobin measurements are used in the diagnosis of haemolytic anaemia and to distinguish it from other types of anaemia. In haemolytic anaemia, haptoglobin levels in the blood decrease significantly. Low levels however may also indicate red blood cell destruction due to sickle cell anaemia or thalassemia. In certain cases of liver disease haptoglobin levels may also be low, as the liver cannot manufacture normal levels of the protein.
As an acute phase reactant haptoglobin levels in the blood are significantly increased in response to infection, inflammation, burns, surgery and trauma. However, haptoglobin is not generally used to diagnose or monitor these conditions.
Publications
Specific Proteins Panel
For more information or to view more reagents within the specific proteins panel, please click here
Complement C4 Reagent
Reagent | Complement C4
Key Benefits of the Randox Complement C4 reagent
Exceptional correlation with standard methods
The Randox methodology was compared against other commercially available methods and the Randox Complement C4 assay showed a correlation coefficient of r=0.98
Wide measuring range
The healthy range for Complement C4 is 7 -49 mg/dl. The Randox Complement C4 assay can comfortably detect levels outside of the healthy range measuring between 2.90 – 152 mg/dl
Excellent stability
Stable until expiry date when stored at +2 to +8°C
Other features of the Randox Complement C4 reagent
- Immunoturbidimetric method
- Liquid ready-to-use reagents
- Stable until expiry date when stored at +2 to +8°C
- Measuring range 2.90 – 152 mg/dl
Ordering information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| CM3846 | R1 3 x 20ml (L) R2 3 x 6ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CM8024 | R1 2 x 11.2ml (L) R2 2 x 4.2ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is the Complement C4 assay used for?
What is Complement C4?
The complement system is one of the major mechanisms of innate immunology consisting of more than 30 plasma and membrane-associated serum proteins which evokes cytolytic immune responses to pathogens, including viruses, bacteria, chemical tissue damage and anything that is classified as foreign to the body. The complement system can be activated through three major pathways: classical, lectin or alternative. Once activated, reactions occur for antibody opsonisation (the process by which a phagocyte marks a pathogen for ingestion and elimination) to fight against the foreign bodies. Activation can also occur when the body produces antibodies for its own tissues that it views as being foreign, which is known as an autoimmune disorder.
During the activation process, Complement C4 splits down into C4b and C4a (peptide). C4b acts as an opsonin and remains bound to the complex at the surface of the pathogen which activates the next step of the process. The small peptide, C4a diffuses away and acts as a chemotactic factor and an inflammatory paracrine.
The Randox Complement C4 assay is used for the quantitative in vitro determination of complement C4 concentration in serum. The Randox Complement C4 assay allows for the diagnosis and monitoring of autoimmune disorders associated with abnormal levels of complement C4 including lupus and rheumatoid arthritis (RA). Higher than normal results may be indicative of cancer or ulcerative whereas lower than normal results may be indicative of lupus, hepatitis, or cirrhosis.
Cell-bound levels of processed complement activation products, especially E-C4d (erythrocyte-bound C4) is a biomarker in the diagnosis and monitoring of systematic lupus erythematous (SLE). For more information on SLE, please click here.
Specific Proteins Panel
For more information or to view more reagents within the specific proteins panel, please click here
Complement C3 Reagent
Reagent | Complement C3
Key Benefits of the Randox Complement C3 reagent
Exceptional correlation with standard methods
The Randox methodology was compared against other commercially available methods and the Randox Complement C3 assay showed a correlation coefficient of r=0.98
Wide measuring range
The healthy range for Complement C3 is 58 – 170 mg/dl. The Randox Complement C3 assay can comfortably detect levels outside of the healthy range measuring between 13 – 502 mg/dl.
Excellent stability
Stable until expiry date when stored at +2 to +8°C
Other features of the Randox Complement C3 reagent
- Immunoturbidimetric method
- Liquid ready-to-use reagents
- Stable until expiry date when stored at +2 to +8°C
- Measuring range 13 – 502 mg/dl
Ordering information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| CM3845 | R1 3 x 20ml (L) R2 3 x 6ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CM8023 | R1 2 x 11.2ml (L) R2 2 x 4.2ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is the Complement C3 assay used for?
What is Complement C3?
The complement system is one of the major mechanisms of innate immunology consisting of more than 30 plasma and membrane-associated serum proteins which evokes cytolytic immune responses to pathogens, including viruses, bacteria, chemical tissue damage and anything that is classified as foreign to the body. The complement system can be activated through three major pathways: classical, lectin or alternative. Once activated, reactions occur for antibody opsonisation (the process by which a phagocyte marks a pathogen for ingestion and elimination) to fight against the foreign bodies. Activation can also occur when the body produces antibodies for its own tissues that it views as being foreign, which is known as an autoimmune disorder. For more information on autoimmune disorders, please click here
During the activation process, Complement C3 splits down into C3b and C3a (peptide). C3b acts as an opsonin and remains bound to the complex at the surface of the pathogen which activates the next step of the process. The small peptide, C3a diffuses away and acts as a chemotactic factor and an inflammatory paracrine.
The Randox Complement C3 assay is used for the quantitative in vitro determination of complement C3 concentration in serum. The Randox Complement C3 assay allows for the diagnosis and monitoring of autoimmune disorders associated with abnormal levels of complement C3 including lupus and rheumatoid arthritis (RA). Higher than normal results may be indicative of cancer or ulcerative whereas lower than normal results may be indicative of lupus, hepatitis, or cirrhosis.
Publications
Specific Proteins Panel
For more information or to visit more reagents within the specific proteins panel, please click here
Rheumatoid Factor
Reagent | Rheumatoid Factor
Rheumatoid Factor Key Benefits
Exceptional correlation
The Rheumatoid Factor assay showed a correlation of r=0.99 against another commercially available method
Applications available
For a wide variety of clinical chemistry analysers including the RX series
Excellent stability
Stable to expiry when stored at 2-8⁰C
Superior Method
Latex Enhanced Immunoturbidimetric method
Ultimate convenience
Liquid ready-to-use reagents
Ordering information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| RF3836 | R1 2 x 20ml (L) R2 2 x 8ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| RF8063 | R1 2 x 8.7ml (L) R2 2 x 4.7ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| RF8345 | R1 1 x 11.7ml (L) R2 1 x 5.7ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Rheumatoid Factor assay used for?
Research has shown that both environmental and genetic factors can affect the production of RF with various biological properties. Although they may be found in all immunoglobulin classes, the RF most frequently detected is the IgM type; present in about 75% of adult patients with RA and about 10% of children with juvenile RA. RF have also been observed in the serum of patients with lupus erythematosus, hepatitis, liver cirrhosis, syphilis and various other conditions; but the RF titre is much lower than in RA.
Specific Proteins Panel
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Rapid Tests / Serology Panel
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HbA1c
Reagent | HbA1c
HbA1c (Indirect)
Key Benefits
Latex Enhanced Immunoturbidimetric method
The Randox assay utilises a latex enhanced immunoturbidimetric method for superior performance
Exceptional correlation to standard methods
A correlation coefficient of 0.98 was obtained with another commercially available method
Excellent precision
The HbA1c assay showed a precision of less than 5% CV
Other Features
- Latex enhanced immunoturbidimetric method
- Liquid ready-to-use reagents
- Stable to expiry when stored at 2-8°C
- Haemoglobin denaturant supplied with the kit
| Cat No | Size | ||||
|---|---|---|---|---|---|
| HA3830 | R1 3 x 14ml (L) R2 3 x 14ml R3 3 x 50ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| HA8321 | R1 4 x 7.8ml (L) R2 4 x 7.8ml R3 4 x 40ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option |
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
HbA1c (Direct)
- Latex enhanced immunoagglutination method
- Liquid ready-to-use reagents
- Stable to expiry when stored at +2 to +8°C
- For use with RX series of clinical chemistry analysers
| Cat Code | Size | ||||
|---|---|---|---|---|---|
| HA8123 | R1 2 x 16.2ml (L) R2 2 x 8.2ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| HA8379 | R1 4 x 12.7ml (L) R2 4 x 6ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| HA4068 | R1 4 x 20ml (L) R2 4 x 8.6ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is HbA1c assay used for?
The concentration of HbA1c in the blood of diabetic patients increases with rising blood glucose levels and is representative of the mean blood glucose level over the preceding six to eight weeks. HbA1c can therefore be described as a long term indicator of diabetic control unlike blood glucose which is only a short term indicator of diabetic control.
It is recommended that HbA1c levels are monitored every three to four months. In patients who have recently changed their therapy or in those who have gestational diabetes it may be beneficial to measure HbA1c levels more frequently, at two to four week intervals.
Diabetes Panel
For more information or to view more reagents within the diabetes panel, please click here
Specific Proteins Panel
For more information or to view more reagents within the specific proteins panel, please click here
