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Genomic Laboratory Technologies

Relatively new to the Randox Group is our Randox Genomics Services department, having been hugely successful in aiding the COVID testing programme, our established sequencing laboratory has been specifically designed and set up to fulfil a unique range of testing from our specialised laboratory in Northern Ireland.

Nucleic Acid Extraction and Isolation

Thermo Scientific KingFisher Flex

Automated nucleic acid extraction instruction that provides high throughput purification of up to 96 samples per run within 40 minutes.

Sample Quality Control

ThermoFisher Scientific Qubit 3.0 & Qubit Flex 


Capable of fast and specific nucleic acid quantification using fluorescence-based dye application, suitable for a lower throughput. More sensitive and accurate protocol than UV absorbance.

ThermoFisher Scientific Varioskan LUX 


Capable of rapid fluorescence-based UV absorbance nucleic acid analysis, suitable for high throughput of processing samples.

Agilent 4200 TapeStation System


An automated electrophoresis solution that with a scalable throughput (1-96 samples) can provide results in 1-2 minutes per plate with excellent reproducibility for sizing, concentration and integrity assessment.

Liquid Handling



Freedom EVO 150 base unit tecans, are automated liquid handling machines, enabling fully traceable, scalable (1-96 samples) automated library preparation including QC and library pooling.

Integra Viaflo 384


Viaflo 384 enables transfers of 24, 96 and 384 samples in a single step, thus increasing pipetting throughput and reproducibility significantly.

Integra Assist Plus


Pipette adapter: accommodates all Integra electronic multichannel pipettes- with fixed and adjustable tip spacing and the D-One single channel pipetting module.


Applied Biosystems SeqStudio Genetic Analyser 


Low-throughput benchtop system that delivers gold-standard Sanger sequencing technology and fragment analysis, easily used across a broad range of applications.

Next Generation Sequencing



The MiSeq System is capable of automated paired-end reads and up to 15 Gb per run, delivering over 600 bases of sequence data per read.

NextSeq 2000


NextSeq 2000 System supports emerging and mid-throughput sequencing applications as well as a broad range of methods such as exome sequencing, target enrichment, single-cell profiling, transcriptome sequencing, and more. It offers an intuitive workflow with load-and-go ease and visual cues about run status. The NextSeq 2000 allows whole-exome sequencing of up to 48 samples in 33 hours.



The most powerful sequencing instrument Illumina produce with the ability to provide scalable throughput for efficient whole-genome, whole exome and whole-transcriptome sequencing through sequencing by synthesis and patterned flow cell technology.


Illumina iScan


An innovative array scanner that supports rapid, sensitive, and accurate imaging of Illumina BeadChips for exceptional genetic analysis results. The iScan System can scan thousands of array samples per day, without sacrificing data quality or reproducibility. It supports an expansive portfolio of genetic analysis assays, from high-throughput genotyping to DNA methylation analysis.

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CDx & Biopharma Services

Next Generation Sequencing (NGS)






Next Generation Sequencing

Next-generation sequencing (NGS) is a sequencing technology that offers speed, scalability and ultra-high throughput. The technology can be used to determine the order of nucleotides in entire genomes or targeted regions of DNA or RNA. NGS has applications in environmental, agricultural and forensic science as well as genomic and clinical research.

NGS Workflow

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NGS Capabilities

Whole Exome Sequencing (WES) is a wildly used NGS method that involves sequencing every protein coding region (approximately 21,000 genes) to identify any variants that may increase the risk of developing certain conditions or impact health/lifestyle. WES can be used across a broad range of applications including genetic disease, population genetics and cancer studies.


  • Attains widespread coverage of coding regions
  • Cost effective alternative to Whole-Genome Sequencing (WGS)
  • Smaller data set provides faster and easy data analysis compared to WGS approaches

Human Whole Genome Sequencing (hWGS) involves sequencing very single base in your DNA (approximately 3.2 billion) to identify any variants that may increase the risk of developing certain conditions or impact health/lifestyle. This sequencing method has many applications including identifying genetic disorders, mutations responsible for cancer progression, as well as monitoring disease outbreaks.



  • High-resolution view of the genome
  • Detection of all variant types
  • Low cost, fast library preparation

16s rRNA gene sequencing involves the analysis of the prokaryotic 16s ribosomal RNA gene which is found in all bacteria and archaea. This sequencing approach is extremely useful for microbiome research studies. 16s rRNA gene sequencing has a number of applications including, environmental, clinical and food



  • Identification and taxonomic classification of bacterial species
  • Fast speed and cost efficient
  • Discovery of novel pathogens


Shotgun sequencing reads all the genomic DNA in the sample, rather than just one specific region. This sequencing method provides a vast amount of genetic information as it can identify archaea, bacteria, fungi and viruses.


  • Less labour intensive than other sequencing methods.
  • Faster process than clone-clone sequencing
  • Requires less DNA



qPCR allows for the analysis of particular variants of specific locations. It is a good choice when interrogating  a small region of DNA on a limited number of samples. Real-time PCR can be used for both qualitative and quantitative analysis.

Advantages and Applications of qPCR 

  • Reactions are run, and data is evaluated in a unified, closed-tube qPCR system.
  • qPCR assays can be used to precisely monitor changes in gene expression.
  • Highly sensitive and reliable variant detection .
  • Quick and Simple Workflow
  • Primary equipment already available in most labs.

Next Generation Sequencing (NGS) Advantages

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    High sample throughput

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    High sensitivity

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    Comprehensive genomic coverage

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    Can sequence thousands of genes simultaneously

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    Low sample input required
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    Fast turnaround time for high sample volumes

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Genotyping Services



Genotyping Services

The Randox Genomics Services Department currently has target genotyping solutions in multiple areas. Genotyping is the process of analysing DNA to detect SNPs of interest. These SNPs are compared to reference SNPs, available from years of genetic research, to determine differences in genetic makeup.

Genotyping Advantages and Applications

Clinical Diagnostics

  • Can help determine whether specific resistance genes or genetic mutations in bacterial strains- make it insusceptible to one or more antibiotic drug.
  • Can be used to help monitor variants during pandemics, identifying when new variants become more predominant.

Clinical Research

  • Allows researchers to focus on genes, variants, and genomic regions of interest relevant to certain disease or traits of interest.
  • Enables the study of populations not supported by standard products and can be used to create personalised drugs.

Food & Agriculture

  • Identifies potential genes for improving breeding and management programs.
  • Can be used to increase yield and improve quality


Pharmacogenomics (PGx) is the study of how a person’s DNA effects their drug response. This is a relatively new field in science but it is expected to be the future of medicine as it focuses on personalised medicine and treating every patient individually.

Microarray Technology for PGx

At Randox we use Illumina’s Infinium Global Diversity Array with Enhanced PGx microarray to test for pharmacogenomic markers. This is the most comprehensive genotyping microarray on the market for pharmacogenomic research. The microarray features over 44,000 genome-wide PGx markers which span more than 20000 pharmacogenomic targets and gives 100% coverage of priority level A and B CPIC genes.

Genotyping Panels

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    GSA + Custom content

    Over 710,000 SNPs across the human genome with additional DTC content.

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    GDA + Enhanced PGx

    Over 1.8 million SNPs across the human genome enhanced with pharmacogenomic specific markers.

Laboratory Technology

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Genotyping Workflow

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Genomics Services



Genomics Services

An End-to-End Genomics Solution

Randox Genomics Services department is fitted with specialised, fully equipped, state of the art testing facilities, designed and set up to fulfil a unique range of end-to-end sequencing solutions inclusive of in-house bioinformaticians and data analysts.

Why Randox?

Randox Laboratories is a global market leader within the in vitro diagnostics industry. Utilising a multitude of platforms, our sequencing and genotyping facility is suited to a wide range of areas of genome sequencing.

Our team of genetic scientists and bioinformaticians provide customisable sequencing and genotyping services for research, development, validation and running of different genomic tests to generate high quality data in line with modern healthcare and future disease insights.

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    A dedicated team of genetic scientists including automation specialists, enabling adaption to testing throughputs changes from call small projects to large scale testing.

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    Huge capacity for storage and accessioning of multiple sample types with fast turnaround times.

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    Specific customised project planning and validation of services, tailored to the needs of each Randox customer.

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    Multiple options for variable throughput from low throughput instruments, to the largest sequencer on the market with targeted solutions in multiple areas.

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    Targeted genotyping solutions in multiple areas

Our Services



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OLINK® | Comprehensive Biomarker Discovery


Let Experts at Randox Run Your Samples

As one of the UK’s first commercial partners of Olink® Proximity Extension Assay (PEA) technology, Randox offer scientists involved in drug development, clinical, or basic life science research, the service they need to run large-scale discovery proteomics.


Randox offer customers access to the entire Olink® protein library of ~3000 protein assays for exploratory proteomics and multiomics.

OLINK® Workflow

OLINK® Features and Benefits

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    Covers all major biological pathways with ~3000 validated protein assays
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    High sample throughput for large scale proteomic studies and research
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    Minimal sample volume with just 60uL for the complete library
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    Exceptional specificity in comparison to mass spec utilising PEA technology
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    Compatible with a wide variety of sample types

Randox Successfully Completes Olink® Concordance Testing

Randox successfully completed the Explore Concordance challenge as beta testers of the Concordance program, certifying the ability to operate the PEA with the same level of competency as the Olink® Analysis Service .

Overall, Randox passed all QC criteria, successfully passing the Olink Concordance Test on Explore 3072.

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Randox Biosciences Launch New Website

Randox Biosciences is delighted to officially announce the launch of our new website which offers a sleek, simple yet informative platform to further your knowledge of our product range and how we can assist you.

After six months of hard work and dedication the website has a fresh look. The interactive aspect of the website provides an easy way for our visitors to learn about Randox Biosciences products and services.

The improved interactive navigation ensures the user enjoys a seamless transition through Randox Biosciences extensive range of products and services with a better experience for both mobile and desktop versions. Potential customers will be able to identify with ease which client segment they fit into – whether it be Academic Research, Biopharma or Clinical Laboratory, enjoying a fully responsive experience.

During the redesign of the Randox Biosciences website we ensured that the brand identity remained consistent throughout, incorporating the brand colours across the site. We in cooperated GIFS (Graphics Interchange Format or moving images) on the top of the homepage as the main header of the website to automatically attract visitors with a moving graphic.

The GIF represents the Biochip Array Technology and the two different diagnostics testing we offer at Randox Biosciences. The GIFs images were continued throughout the website to highlight the three industries we cater for. Brochure downloads are also available on the new website for customers to enhance their knowledge with more in-depth information of Randox’s products and services.

The incorporation of an overview video on the homepage enables website users to gain a snapshot view of Randox Biosciences products and services. The idea of presenting the video first is to allow the visitor to understand our company from a visual method rather than processing a lot of written information.

73% of consumers worldwide would prefer seeing a video than text because they are more “entertaining”.1 The video itself, captures exactly what Randox Biosciences is and what we do. A short yet effective video clearly illustrates the science behind of Randox Biosciences and how this reaches the patient through drug discovery and development.

Julie-Ann O’Hare, Director of Randox Biosciences, commented:

“I am thrilled with the final product of the website, which I hope our current and potential customers will utilise it with ease. The website is another aspect of aligning our marketing strategy and branding to ensure our messaging is clear, concise and consistent across the board. We look forward to the continuation of promoting Randox Biosciences in the digital landscape throughout 2019.”

An e-commerce section of the website is under construction for the sale of our BioReagent products, which they are very excited to launch upon completion in Q3.

Check out our new and improved website for yourself. It is available at: https://www.randoxbiosciences.com/. Also, to find out more email us at info@randoxbiosciences.com

  1. http://rocketium.com/academy/6-reasons-why-customers-prefer-video-ads-to-the-text-ones





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