Your heart is amazing. Not only is it your most critical organ but also one of the most hard-working. The average adult heart beats around 100,000 times a day, acting as a giant pump for all the blood in your body. Indeed, every day your heart pumps over nine litres of blood through a system of blood vessels over 60,000 miles long – it’s little wonder, then, the importance placed on looking after such a vital muscle.
Over time, and influenced by lifestyle choices, the heart grows weaker, needing to work harder to fulfil its function. Crucial lifestyle changes now could limit your risk of developing serious cardiac conditions, such as Cardiovascular Disease (CVD) in the future.
While lifestyle changes may help to limit your risk of CVD, and related heart condition, it is impossible to eradicate it completely for everyone. Cardiovascular disease is the number one cause of death globally. Across the world, 17.7 million people died from CVDs in 2015. In the UK, it accounts for nearly one death around every eight minutes.
But early screening and improved access to cutting-edge diagnostics could lower this figure significantly. According to the WHO there are 8 key risk factors of developing CVD and they account for as much as 61% of all cardiovascular deaths, these include;
The harmful substances in tobacco can damage and narrow blood vessels, causing CVDs. Smoking kills approximately half of persistent smokers, around 14% of deaths from circulatory disease can be attributed to smoking.
High Blood Pressure
High blood pressure (hypertension) is one of the most important risk factors of CVD, if your blood pressure is too high your blood vessels can become damaged.
Being overweight or obese increases the risk of developing diabetes and high blood pressure, both of which can cause CVD. You’re at an increased risk of CVD if your BMI is 25 or above.
Cholesterol is a fatty substance found in the blood, high levels of cholesterol can cause blood vessels to narrow and increase the risk of developing a blood clot. Reducing the populations LDL-Cholesterol by 5% would prevent 64,000 cases of CVD.
Lack of Physical Activity
If you don’t exercise regularly, it’s more likely you’ll develop high blood pressure, high cholesterol levels and become overweight. All of which are risk factors of CVD. Exercising regularly helps to keep the heart healthy.
Other CVD risk factors include an excessive alcohol intake, an unhealthy diet and high levels of blood glucose.
Randox has developed the RX series of clinical chemistry analysers for superior semi-automated and fully automated testing. The RX series extensive dedicated test menu goes beyond routine testing and has many unique and high-performance tests available. Our range of tests covers many tests for the diagnosis and monitoring of cardiac diseases.
|Cholesterol||CRP Full Range(0.3-160mg/l)||Direct LDL Cholesterol||sLDL|
|CK-MB||CRP High Sensitivity||Heart-Type Fatty Acid Binding Protein (H-FABP)||Triglycerides|
|CRP||Direct HDL Cholesterol||Myoglobin|
Our world leading test menu of high quality reagents guarantees excellence in patient care ensuring unrivalled precision and accuracy reducing costly test re-runs or misdiagnosis and offering complete confidence in results.
The RX series clinical chemistry analysers provide laboratories with a robust and smart solution ensuring you maintain a consistent workflow and can provide accurate results first time, every time. Offering excellent customer support services, our trained engineers are on hand to work with you in preserving the continuity of your operations while maximising the potential of your RX series instrument.
For more information visit: https://www.randox.com/clinical-chemistry-analysers/
Cardiac health and regular cardiovascular screening is important to enable risk factors to be detected in their earliest stages. Randox reagents offer a comprehensive cardiology product profile which includes high performance reagents for the detection of conventional risk factors, as well as emerging biomarkers associated with further risk.
sLDL cholesterol is a vital cardiac risk marker which utilises the “Denka Seiken” method which produces results in less than ten minutes. Research has shown individuals with a predominance of sLDL have a 3-fold increased risk of myocardial infarction (MI), even for those who HDL, LDL, Total Cholesterol and Triglyceride levels are considered ‘normal’. Elevated levels of sLDL are associated with a sedentary lifestyle, a diet high in saturated fat, insulin resistance, pre-diabetes and genetic disposition. Measurement of sLDL allows the clinician to get a more comprehensive picture of lipid risk factors and tailor treatment accordingly. Reducing LDL levels reduce the risk of both CVD and MI.
For more information visit: www.randox.com/sldl-cholesterol/
Lipoprotein (a) is a major independent genetic risk factor for premature CVD and elevated levels can occur in patients with otherwise normal lipid levels, therefore providing much needed information in relation to a patient’s risk of developing CVD.Along with other tests, Lp(a) can provide additional information on a patient’s risk factor of developing cardiovascular disease (CVD).
The Randox Lp(a) assay is one of the only methodologies on the market that detects the non-variable part of the Lp(a) molecule and therefore suffers minimal size related bias providing more accurate and consistent results.
For more information visit: www.randox.com/lipoprotein-a/
HDL3 Cholesterol is a smaller and more dense sub fraction of the HDL particle. HDL comprises of several subclass particles, which differ in their sizes, densities and components. HDL is the scavenger of cholesterol within arterial walls and the levels of HDL3 is too low, the ability to remove this cholesterol is reduced. Therefore, it is widely accepted that there is an inverse correlation between HDL3 and cardiovascular disease risk.
For more information visit: https://www.randox.com/hdl3/
Cardiology and Lipid Testing Panel
- Apolipoprotein A-I
- Apolipoprotein A-II
- Apolipoprotein B
- Apolipoprotein C-II
- Apolipoprotein C-III
- Apolipoprotein E
- Cholesterol (sLDL)
- Cholesterol (HDL)
- Cholesterol (LDL)
- Cholesterol (Total)
- Cholesterol (HDL3)
- Lipoprotein (a)
- High sensitivity CRP
- Heart Type Fatty Acid Binding Protein (H-FABP)
Browse our full cardiology and lipid testing panel here.
To request an application for your specific analyser, contact us at firstname.lastname@example.org
When diagnosing and monitoring CVD, it is vital that laboratories have a robust Quality Control (QC) system in place to ensure the accuracy and reliability of the results produced. The Acusera Cardiac Controls have been designed to cover a wide range of cardiac markers at clinical decision levels eliminating the need for additional low level controls at extra expense. Available in both liquid ready-to-use and lyophilised formats, they are ideal for use at the point-of-care and in the laboratory. Manufactured from 100% human serum a matrix similar to that of the patient is guaranteed.
Liquid Cardiac Control
- Liquid ready-to-use
- 100% human serum
- Assayed target values provided for 8 cardiac markers
- Cut off levels for Troponin I and T in line with internationally recommended levels
- Stable to expiry date at 2°C – 8°C
- Open vial stability of 30 days at 2°C – 8°C for all analytes
|Myoglobin||Troponin I||Troponin T|
|NT – ProBNP||CK-MB (Mass)||D-dimer|
Find out more about our Liquid Cardiac Quality Control here.
Other cardiac quality controls include:
For more information, visit our Cardiac Quality Controls page.
RIQAS Cardiac Programme
The RIQAS Cardiac EQA programme is designed to monitor the performance of up to 7 clinically significant cardiac markers. Two flexible reporting options are available to suit the needs of all laboratory sizes.
- Accredited to ISO/IEC 17043
- Lyophilised for enhanced stability
- 100% human serum
- Bi-weekly reporting
- Submit results and view reports online via RIQAS.Net
- Register up to five instruments at no extra cost
For more information, visit our RIQAS Cardiac Programme page.
Our Randox Health clinics offer comprehensive health testing as part of our Signature, Everyman and Everywoman packages to identify and assess risk of developing Cardiovascular Disease. Our clinics utilise the same cutting-edge tests and quality control that we have available to clinical laboratories globally, as well as our patented Biochip Array Technology (BAT).
For more information visit: https://www.randoxhealth.com/
The World Heart Federation (WHF) is the acting global voice in leading the universal fight against cardiovascular disease (CVD). Part of the WHF mission is to ensure heart health equity for everyone. They believe everybody is entitled to cardiovascular health and well-being through health promotion, access to prevention, control and management of CVD 1.
World Heart Day falls on the 29th September where people make a promise to promote and implement healthier lifestyles to maintain a happy and healthy heart, reducing the potential risks of heart disease and stroke. CVD takes the lead being the number one cause of death world-wide 2 relating to all heart and circulatory diseases consisting of coronary heart disease, angina, heart attack, congenital heart disease, hypertension, stroke and vascular dementia 3.
According to the World Health Organisation2:
- An estimated 17.9 million people died from CVD in 2016, representing 31% of all global deaths. Of these deaths, 85% were due to heart attack and stroke.
- Out of the 17 million premature deaths (under the age of 70) due to noncommunicable diseases in 2015, 82% were in low- and middle-income countries, and 37% were caused by CVD.
- Most cardiovascular diseases can be prevented by addressing behavioural risk factors such as tobacco use, unhealthy diet and alcohol abuse.
Cytokines have a central role within the immune system; they are a category of signalling molecules that mediate and regulate immunity, inflammation and hematopoiesis 4. Cytokine and inflammatory mechanisms have major implications for the vascular system and can lead to CVD.
Cytokines exist in broad families that are structurally related but exhibit diverse function. The major classes of cytokines include: pro- and anti-inflammatory cytokines, cytokines of neutrophil and eosinophil recruitment and activation, cytokines derived from T-helper (Th) and T-regulatory (Tregs) cells, and cytokines of T-cell recruitment and growth factors. 5
Randox offers a comprehensive menu of 26 cytokine, cytokine receptors and growth factors over four multi-analyte arrays. Each cytokine assay is performed on biochip array technology with spatially discrete test regions containing antibodies specific to each of the analytes. The combination of highly specific antibodies and advanced chemistries enables up to 12 cytokines and growth factors to be detected simultaneously in a single sample.
Cytokine Array I Cytokine Array III
- Epidermal Growth Factor (EGF) – Granulocyte Macrophage Colony Stimulating
- Interferon-y – Interleukin-5
- Interleukin-1a – Interleukin-15
- Interleukin-1b – Macrophage Inflammatory Protein-1a
- Monocyte Chemotactic Protein-1
- Tumour Necrosis Factor-a
- Vascular Endothelial Growth Factor
Cytokine Array IV Cytokine Array V
- Matrix Metalloproteinase-9 – Interleukin-3
- Soluble IL-2 Receptor a – Interleukin-7
- Soluble IL-6 Receptor – Interleukin-13
- Soluble Tumour Necrosis Factor Receptor I – Interleukin-12 p70
- Soluble Tumour Necrosis Factor Receptor II – Interleukin-23
Key Benefits of Randox Cytokine Arrays:
- Multiplex testing from a single sample.
- Suitable for human serum and plasma samples.
- Small sample volume required.
- Excellent analytical performance.
- Fast throughput.
- Applicable to fully automated and semi-automated Evidence analysers.
Randox manufacture the majority of assay raw materials in-house and can therefore take a more tailored approach, by adapting assays to the needs of your research project to best fit your individual requirements.
Randox Biosciences Products and Services
Want to know more about Randox?
Contact us or visit our homepage to view more.
Randox Food Diagnostics are attending AOAC Denver 2019
Randox Food Diagnostics are exhibiting at AOAC in Denver. Various contaminants are administered to animals during the farming process to treat infection and maintain herd health. Regulations are often adhered to, as quality control procedures are put in place to ensure the safe supply of agricultural produce and this is where Biochip technology can streamline the quality control process. By offering a system that can analyse up to 48 sample simultaneously, our technology delivers higher throughput which in turn saves time and money on laboratory costs and labour.
Randox Food and Biochip Array Technology
Biochip Array technology (BAT) is designed with the aim of revolutionising the screening practices of your laboratory. Designed to work across a wide variety of matrices, BAT uses a micro-spotting technique to create an assay that can detect and provide quantitative results for up to 44 residues from a single sample.
The market leading 9mm x 9mm ceramic chip brings the capacity to detect the range of antibiotics, anti-parasitic, anti-inflammatory, growth promoting and mycotoxin residues simultaneously in a range of food and feed samples.
AOAC’s annual meeting is taking place this September in Denver. The meeting organises scientific sessions, roundtable discussions, workshops and poster presentations discussing a variety of analytical methods and requirements. Attended by scientists from across the world the conference discusses science at a different level.
At AOAC Denver you will get the opportunity to speak to our experts on the Biochip Array Technology. By visiting booth #416 you will get an introduction to BAT and find out how the technology can perfectly fit any of your screening needs.
To learn more about Biochip Array Technology contact email@example.com or stop by Booth #416 at AOAC Denver 2019 and chat the Randox Food team!
Find out more about AOAC.
Want to know more?
Contact us or visit our Randox Food Diagnostics website.
Meat & Seafood
On Sunday 14th April 2019, a team of brave Randox colleagues faced their fears and took part in an abseil from the top of Belfast Castle. Scaling the heights of Cavehill, our fourteen daring Randox thrill seekers enjoyed views over Belfast before they stepped over the edge.
The event took place to raise funds for Randox’s charity partner AWARE NI, the depression and bipolar charity of Northern Ireland.
Congratulations to our abseil participants! While this may be something else ticked off the ‘bucket list’, it also, most importantly, is a fantastic effort in raising awareness and funds for the work of this very worthwhile cause.
Well done to everyone with your fundraising. You have all worked very hard and raised a fantastic amount both in cash donations and via JustGiving – around £2200 so far and counting!
We hope you enjoy the photographs from the day. If you would still like to donate, please visit: https://www.justgiving.com/teams/randox-aware-belfast-castle
Once again, many thanks on behalf of both Randox and AWARE NI to the Randox abseilers for their enthusiasm and fundraising efforts on behalf of both Randox and AWARE NI.
For more information about the abseil or our charity partnership with AWARE NI, please contact RandoxPR@randox.com.
National Heart Month is held every February to raise awareness and remind the public of the importance of taking care of your heart. Every day, your heart will beat approximately 100,000 times and it is responsible for pumping blood throughout the body via the circulatory system, supplying oxygen and nutrients to the tissues and removing carbon dioxide and other wastes. 1
British Health Foundation (BFH) states that over 7 million people are living with heart and circulatory disease in the UK: 3.5 million men and 3.5 million women. 2
There are many different heart conditions and problems that can arise which include angina, heart attack, heart failure and abnormal heart rhythms, congenital heart disease and inherited heart conditions which are highlighted further below:
Angina is a chest pain which is often caused when the coronary arties become partially blocked. It causes an uncomfortable feeling of heaviness or tightness which is often mistaken to indigestion. 3
Whereas a heart attack is when the arteries are completely blocked which can cause permanent damage to the heart muscle therefore, it is essential to be aware of the symptoms. The signs are similar to angina although it is more severe. This may include feeling pain in the arms, jaw, neck and back, lightheadness, sweating, nausea and breathlessness. 3
Heart failure is the most dangerous condition. It often occurs when the individuals heart is too weak to pump blood around the body making it difficult for the person to breathe. There are two types of heart failure. Acute heart failure which can occur suddenly or chronic heart failure which develops over time. 3
Being aware of the different types of heart disease and the symptoms can save a person’s life in the long-run. There are many ways to avoid developing heart disease. One of the simple changes could include having a healthier diet to reduce your risk of developing heart disease and maintaining a healthy weight. A healthy diet could include plenty of fruit and vegetables, starchy food, choosing whole grain varieties, including some dairy products and a small amount of fat and sugar in your diet. Exercising regularly can benefit your heart and its health, making small changes to your lifestyle can make a difference for example, walking to work or school instead of driving or taking public transport, taking the stairs instead of using the lift or even taking on a hobby! Quitting smoking, decreasing your alcohol intake, eating healthier and exercising more will make a huge impact to your health!
Randox offer the Cardiac Risk Prediction Array on their Evidence Investigator. We developed a rapid array which will allow all 19 SNPs to be genotyped simultaneously on one single sample. The genotype information is then put into an algorithm which weights each SNP and calculates a CHD genetic risk score. This score is combined with common risk factors and an overall CHD risk score is calculated. A SNP which can predict response to statin therapies is also included. The results are easy to interpret using our Evidence Investigator which allows for more accurate classification and prevention actions to be taken.
For further information about the Randox Cardiac Risk Prediction Array or our Evidence Investigator, please email: firstname.lastname@example.org or visit our newly improved website: https://goo.gl/8qkYkg
This February, Randox Health are focusing on Heart Health. Heart health is becoming a much greater talked about subject because of health trends and figures. There are around 7 million people living with heart and circulatory disease in the UK. Heart and circulatory disease causes more than a quarter (26%) of all deaths in the UK; that’s nearly 160,000 deaths each year – an average of 435 people each day or one death every three minutes. Facts like these from BHF show us how how important our hearts are! Maintaining and having a healthy heart is essential to cut down your risk of heart disease.
Ways to Improve your Health
There are a number of things you can do to lower your risk of getting heart disease, and at the same time improve overall health. Lets look at three ways to lower your risk and help you become healthier:
- Managing a healthy weight
- Eating healthier
- Getting active
What You Can Do
All three of the above will lower your risk of heart disease and all are linked so by improving one it will help the others. To manage a healthy weight, first you need to work out what a healthy weight is for you. There are two main ways to tell whether you need to lose weight: your Body Mass Index (BMI), and your waist measurement. the risk of heart disease begins to increase at a BMI of 23, and people with a BMI of 27.5 will be at high risk.
Men with a waist of over 94 cm are at an increased risk of heart diseases and over 102 cm are at a severe risk. Women with a waist over 80 cm are at an increased risk and at 88 cm are at a severe risk. If you fall in these risk areas, eating well and being more physically active can help you reduce your weight.
A healthy diet can help reduce your risk of developing coronary heart disease and stop you gaining weight. This also reduces your risk of diabetes and high blood pressure. A well-balanced diet should include at least 5 portions of fruit and veg a day. Try to vary the types of fruit and veg you eat.
You should try to replace saturated fats with small amounts of mono and polyunsaturated fats. Try and cut down on foods that contain trans fats as it can raise your cholesterol levels. Lowering your salt intake can improve your blood pressure and lower your chance of coronary heart disease. Eating a healthy well-balanced diet can make it a lot easier to control and maintain your weight.
Get Active! The BHF say that physical activity can help reduce your risk of heart and circulatory disease. It also links in and helps you control your weight! Being active reduces blood pressure and cholesterol and can even improve your mental health. If you do all three of these points not only will it lower your risks of heart disease but will improve your overall health!
Randox Health: What We Do and How We Can Help
This month we are focusing on heart heart, so make sure to check out our blogs with information about how to keep a healthy heart. If you’re worried about your heart health or have a family history of heart disease, contact a member of our team today for more information on how we could help you! We are determined to help you get to the heart of the matter and see what’s really going on with your heart. This Valentines day give a gift to the one you love that really matters, the gift of health.
Find out more here: https://www.randoxhealth.com/our-packages/
Mental Health Day is held every year on the 10th of October since 1992 1 to raise awareness and support against the stigma. 1 in 4 people in the UK will experience mental illness each year 2.
“Everyone has mental health. It involves our emotional, psychological and social well-being and it affects how we feel, think and act” 3 Mental Health can also affect an individual’s daily life, relationships and physical health. Lives are taken as a result from mental health therefore it is vital that we acknowledge the syndromes of mental health in order provide help and support.
Randox held a mental health and well-being month. This entailed a yellow shirt day, an organised free-fall abseiling from the dome of Victoria Square, cake sale and yoga throughout the month! Randox care for the health of their staff and want to ensure that mental health is just as important as physical and that it is ok to not be ok.
At Randox Biosciences, we are devoted to the development of innovative diagnostic tests to improve patient care worldwide. We strive to maintain a stress-free environment for our employees by recognising the signs of mental health to lower mental health in order to create a positive working environment.
- Reach out. If you feel like you experience mental health, talk to someone. It will lift the weight off your shoulders and you could get the help you require.
- Do something you enjoy! It can be a hobby or spending time with your family and friends.
- Go for a walk. Fresh air can clear a head.
- Take time out of digital devices. Technology have taken over and sometimes taking an hour off social medias can help.
- Sleep more. Having a full night’s sleep can change your mood completely.
- Eat well and exercise. It is easy to forget your physical health. When you have a nutritional diet and exercise regularly, you’re stronger and healthier.
- Avoid alcohol and drug-use.
Help-lines for mental health include the following:
To find out more email us at email@example.com
On Sunday 21st October 2018, a team of brave Randox colleagues faced their fears and took part in a ‘freefall’ abseil from the dome of Victoria Square, Belfast. Scaling the heights of the 147ft, almost 45m drop, our fourteen daring Randox thrill seekers enjoyed views over Belfast before they stepped over the edge of the lilypad and ventured down to the ground floor of one of Belfast’s most recognisable structures.
The event took place as part of Randox’s Mental Health and Wellbeing Month throughout October, which sought to raise awareness of mental health and wellbeing among staff members while fundraising for our two charity partners – AWARE NI and Ulster University’s Mind Your Mood. Events in the month have not only included a Victoria Square abseil but also a Wear Yellow Wednesday for World Mental Health Day, a fundraising coffee morning and internal fundraising bake sales along with yoga and relaxation class offers for staff members.
Congratulations to those all abseil participants! While this may be something else ticked off your ‘bucket list’, it also, most importantly, is a fantastic effort in raising awareness and funds for the work of AWARE NI, Northern Ireland’s depression charity.
Well done to everyone with your fundraising. You have all worked very hard and raised a fantastic amount – around £2000 so far and counting!
We hope you enjoy the photographs from the day. If you would still like to donate, please visit https://www.justgiving.com/companyteams/RANDOXAWARE
Once again, many thanks on behalf of both Randox and AWARE NI to the Randox abseilers for their enthusiasm and fundraising efforts on behalf of both Randox and AWARE NI.
For more information about the abseil or Randox Mental Health & Wellbeing Month, please contact RandoxPR@randox.com.
Today is World Mental Health Day and Randox is getting involved to raise money for our two charity partners – AWARE NI and Ulster University’s Mind Your Mood.
Colleagues across Randox sites in Northern Ireland have been donning yellow in order to raise awareness of mental health and wellbeing and also to raise funds for these two fantastic causes.
Wear Yellow Wednesday is part of a series of events taking place at Randox as part of Randox Mental Health & Wellbeing Month – an initiative which encourages staff to take care of their mental wellbeing and seeks to support the work of AWARE NI and Mind Your Mood.
The month also entails a charity ‘freefall’ abseil from the dome of Victoria Square when 14 brave Randox colleagues will scale the heights to raise money for AWARE NI. You can visit their JustGiving page here: https://www.justgiving.com/teams/RANDOXAWARE
AWARE NI is the depression charity for Northern Ireland. They have two offices in both Belfast and Derry. AWARE has an established network of 25 support groups in rural and urban areas across the country which are run by trained volunteers. AWARE also deliver mental health and well being programmes into communities, schools, colleges, universities and workplaces.
Ulster University’s Mind Your Mood initiative is a service managed by Student Support but designed and delivered by students to have lived experiences of mental health illness. Mind Your Mood was created to help build resilience to avoid mental illness, provide support at the earliest point to avoid progression of mental illness to something more serious and threatening and to build resilience and awareness and provide support to help students with already-diagnosed mental illness.
For more information on Randox Mental Health & Wellbeing Month please contact the Randox PR team on 028 9442 2413 or by emailing firstname.lastname@example.org
This month is Mental Health & Wellbeing Month at Randox. Throughout the month, we’ll be highlighting how you can take care of your mental health and wellbeing to not only improve mood and self-esteem but also to promote the many physical health benefits associated with good mental healthcare.
Mental wellbeing is as important as physical health. For complete health and wellbeing, both must be given equal attention as one affects the other. When you’re in pain, your mental health will also be under strain as mindset plays a role in our pain threshold capacity. When you are under mental stress, your physical health can also pay the price. Such is the case for anxiety sufferers who quite often report stomach and bowel issues as a consequence.
At Randox Health our health checks are the most advanced in the world, helping to extend your life through the world’s most advanced technology. Testing up to 350 different markers of irregularity, deficiency and disease in the body, we can give you the most comprehensive picture of your overall health and wellbeing available.
Mental health issues, such as low mood, anxiety and depression, can sometimes be aggravated by certain deficiencies such as a shortage of vitamin D. While supplements are unlikely to eradicate a serious mental health issue, they may help to improve symptoms and should be a first-resort before more advanced treatment, such as antidepressants, are prescribed.
At Randox Health, you can be sure of the most advanced testing – including the areas of vitamin and mineral levels. Mental health and physical health are deeply connected. Make sure you know all you can about your physical wellbeing in order to address your mental wellbeing in the most informed and comphrehensive manner.
Visit https://www.randoxhealth.com/ or call 0800 2545 130 to find out about Randox Health programmes available.