Cytokine Testing Solutions
Cytokine Testing Solutions
COVID-19 Risk Stratification and Treatment Monitoring
Randox offer testing solutions for a comprehensive range of cytokines, cytokine receptors and growth factors designed to assist with COVID-19 risk stratification, monitoring of treatment efficacy and recovery. Utilising patented Biochip technology up to 12 cytokines and growth factors may be detected simultaneously from a single patient sample.
Cytokines play a vital role in the immune system and are known to be involved in the body’s response to a variety of inflammatory and infectious diseases. The over stimulation of these cytokines in response to infection is referred to as a ‘cytokine storm’ and strongly correlates with poor disease outcomes.
Cytokine storms are a common complication of SARS-CoV-2 (COVID-19) infection triggering viral sepsis, where viral replication and excessive, uncontrolled systemic inflammation may lead to pneumonitis, Acute Respiratory Distress Syndrome (ARDS), respiratory failure, shock, multiple organ failure, secondary bacterial pneumonia, and potentially death.
Why Choose Randox Cytokine Arrays?
- Simultaneous detection of up to 12 cytokines and growth factors from a single patient sample
- Fully automated and semi-automated solutions available to suit all laboratory throughputs
- Comprehensive test menu comprising 26 cytokines, cytokine receptors and growth factors
- Suitable for use with serum and plasma samples
- Excellent analytical performance
- Availability of complementary quality controls for a complete testing package
Cytokine Array I
Analytes
- Interleukin-1 Alpha (IL-1α)
- Interleukin-1 Beta (IL-1β)
- Interleukin-2 (IL-2)
- Interleukin-4 (IL-4)
- Interleukin-6 (IL-6)
- Interleukin-8 (IL-8)
- Interleukin-10 (IL-10)
- Interferon Gamma (IFNγ)
- Epidermal Growth Factor (EGF)
- Monocyte Chemotactic Protein (MCP-1)
- Tumour Necrosis Factor Alpha (TNFα)
- Vascular Endothelial Growth Factor (VEGF)
Ordering Information
| Cat. Number | Description | Kit Size |
|---|---|---|
| EV3508 | Cytokine Array I Evidence | 360 Biochips |
| EV3544 | Cytokine Array I Evidence | 180 Biochips |
| EV3513 | Cytokine Array I Evidence Investigator | 54 Biochips |
| EV3623 | Cytokine Array I High Sensitivity Evidence Investigator | 54 Biochips |
Cytokine Array III
Analytes
- Interleukin-5 (IL-5)
- Interleukin-15 (IL-15)
- Granulocyte Macrophage
- Colony Stimulating Factor (GM-CSF)
- Macrophage Inflammatory Protein-1 Alpha (MIP-1 α)
| Cat. Number | Description | Kit Size |
|---|---|---|
| EV3680 | Cytokine Array III Evidence | 180 Biochips |
| EV3678 | Cytokine Array III Evidence Investigator | 54 Biochips |
Cytokine Array IV
Analytes
- Matrix Metalloproteinase-9 (MMP-9)
- Soluble Interleukin-2 Receptor Alpha (sIL-2Rα)
- Soluble Interleukin-6 Receptor (sIL-6R)
- Soluble Tumour Necrosis Factor I (sTNFR I)
- Soluble Tumour Necrosis Factor II (sTNFR II)
| Cat. Number | Description | Kit Size |
|---|---|---|
| EV3659 | Cytokine Array IV Evidence | 180 Biochips |
| EV3661 | Cytokine Array IV Evidence Investigator | 54 Biochips |
Cytokine Array IV
Analytes
- Interleukin -3 (IL-3)
- Interleukin-7 (IL-7)
- Interleukin-12 p70 (IL-12p70)
- Interleukin-13 (IL-13)
- Interleukin-23 (IL-23)
| Cat. Number | Description | Kit Size |
|---|---|---|
| EV3666 | Cytokine Array V Evidence Investigator | 54 Biochips |
Evidence Investigator
The Evidence Investigator is a benchtop, semi-automated analyser capable of screening 54 patient samples and up to 44 analytes simultaneously using Randox Biochip technology. Ideal for medium to high throughput testing, the Evidence Investigator test menu comprises immunoassay testing and molecular diagnostics on a single platform. Find out More
Evidence
Evidence is a fully automated analyser utilising Randox Biochip technology to screen up to 88 patient samples and up to 44 analytes simultaneously for complete patient profiling. Our comprehensive test menu comprises cytokines, endocrines, tumour markers, thyroid hormones, adhesion molecules and drugs of abuse. Find out More
Bilirubin Linearity Verifier
Our Bilirubin verifier contains both Direct Bilirubin and Total Bilirubin so testing is fully covered. Dedicated for use on Roche
Cobas systems, this verifier spans five levels ensuring the instruments entire reportable range is measured.
Features & Benefits
- Lyophilised for enhanced stability
- 5 levels provided
- Open vial stability of 10 days at 2ºC to 8ºC
- Shelf life of up to 2 years from date of manufacture
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Acusera Enzyme Linearity Verifier | 5 x 3mL | 10 | LV10366 | |
Analytes
- Direct Bilirubin
- Total Bilirubin
Enzyme Linearity Verifier
Our Enzyme Linearity Verifier contains 10 commonly tested enzymes in one unique multi-marker verifier allowing you to
consolidate testing. Spanning 5 clinical levels, this verifier ensures the systems entire reportable range is measured. Designed
specifically for use with Roche Cobas systems, our Verifier is available in a convenient liquid frozen format.
Features & Benefits
- Convenient, liquid frozen format
- 5 levels provided
- 14 day stability when stored at 2ºC to 8ºC
- Shelf life of up to 2 years from date of manufacture
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Acusera Enzyme Linearity Verifier | 5 x 3mL | 10 | LV10366 | |
Analytes
- ALT
- ALP
- a-Amylase
- Pancreatic Anylase
- AST
- CK
- CKMB
- yGT
- LDH
- Lipase
Clinical Chemistry Linearity Verifier
Our Clinical Chemistry Linearity Verifier comprises 17 common chemistry assays, supplied in a liquid frozen format. Designed specifically for use on Roche Cobus analysers, this verifier spans five levels ensuring the instruments entire reportable range is measured.
Features & Benefits
- Convenient, liquid frozen format
- 5 levels provided
- 7 day stability when stored at 2ºC to 8ºC
- Shelf life of up to 2 years from date of manufacture
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Acusera Verify Clinical Chemistry Linearity Verifier | 5 x 5mL | 17 | LV10390 | |
Analytes
- Albumin
- BUN
- Calcium
- Chloride
- Creatinine
- Glucose
- Iron
- Lactate
- Lithium
- Magnesium
- Phosphate
- Potassium
- Sodium
- Total Protein
- Triglycerides
- Uric Acid
- Total Cholesterol
RIQAS Point of Care
Designed to improve the quality of Point of Care Testing (POCT) in locations such as pharmacies, GP surgeries, hospital out patient departments, sports clinics, supermarkets, diagnostic/treatment and walk-in centres, RIQAS Point of Care provides independent evidence of the accuracy and reliability of test results. Randox International Quality Assessment Scheme (RIQAS) is the world’s largest EQA scheme with over 47,000 participants in more than 139 countries.
Why RIQAS Point of Care?
About RIQAS Point of Care
How it Works
On a monthly basis we will distribute an identical sample of blood to all participating sites. Each participating site will test the sample in the same way they would test a real patient sample, then return their test results to RIQAS within a set time. The scheme is unique in distributing whole blood samples rather than serum based samples, this ensures that samples act identically to real patient samples at the point of care.
An electronic report is then sent to participants, comparing their results with other participants using the same analyser. Satisfactory and unsatisfactory performance is represented using a traffic light system, allowing instant identification of any issues. A more detailed breakdown of performance may be obtained if further information is required. With time, an overall picture will emerge showing whether results are consistently accurate and reliable or whether there may be an underlying analyser and/or operator issue.
Tests and Analysers
Test Role HbA1c • Diagnosing diabetes mellitus
• Monitoring treatment
• Encouraging self-managementTotal Cholesterol & HDL Cholesterol • Risk factors for heart disease
• Monitoring lipid lowering therapyC-Reactive Protein (CRP) • Early detection of infectious disease
• Identifying need for antibiotic treatmentGlucose • Diagnose and monitor diabetes
• Monitor for the presence of hypoglycaemia
(low blood glucose) and hyperglycaemia (high blood glucose)International Normalised Ratio (INR) • Used to measure the effect of anticoagulant
drugs such as warfarin
• Help diagnose a bleeding disorder; to help
estimate the severity of liver diseaseKetones • To determine whether excessive ketones are
present in the blood, to detect diabetic
ketoacidosis (DKA)Note – The RIQAS Point of Care range is constantly expanding to include new tests and analysers. Please contact us if your desired analyser or test is not currently displayed.Ordering Information
Panel Catalogue Number Lipids RQ9181/A Lipids + 1 panel RQ9181/B Lipids + 2 panels RQ9181/C Additional Sample RQ9181/D What Participants Say
Our unrivalled commitment to quality and service ensures high levels of customer satisfaction, this is evident from the responses to our latest customer satisfaction survey:
“All in all a quick and efficient service”
“Good online system”
“Very helpful team”
“Excellent training”
“They are an experienced team”
“Very satisfied with the service that we receive”
“Very good value for money”
“The website is great”Distribution Dates
Distribution Month Sample Distributed Result Submission Deadline March 2020 2nd March 11th March April 2020 6th April 15th April May 2020 4th May 13th May June 2020 1st June 10th June July 2020 6th July 15th July August 2020 3rd August 12th August September 2020 7th September 16th September October 2020 5th October 14th October November 2020 2nd November 11th November December 2020 7th December 16th December Importance of Quality Assurance
Quality assurance is an essential aspect of any clinical/diagnostic testing service and is aimed at ensuring the accuracy and reliability of patients’ results. The right result allows the right clinical advice to be offered in a timely manner. Quality assurance operates at two levels:Internal Quality Control
Internal Quality Control includes operator training/ competency assessment, analyser/ test system maintenance, and adherence to policies/ processes. Whilst some point of care analysers include inbuilt quality checks, cross-check analysis against samples with known levels provides immediate assurance and evidence that a patient’s result is safe to report.External Quality Assessment
External Quality Assessment involves analysis of samples with unknown levels that have been distributed by an external organisation. Participants are informed how their results compare with other participants, hence providing independent evidence of performance. Increasingly, participation in an external quality assessment scheme is becoming a mandatory requirement where health and healthcare services are being provided.
EQA provides assurance to both staff and customers that testing provides accurate and reliable results.Want to know more?
Visit our Importance of EQA page to learn more.
Want to know more?
Contact us or download the RIQAS Point of Care catalogue to learn more.
Continue Reading
Frequently Asked Questions
RIQAS
Contact Us
Ethanol Calibrator/Control Set
Dedicated calibrator and control set designed for the calibration and quality control of the Randox Ethanol assay.
Features & Benefits
- Liquid ready-to-use
- Human urine
- Stable to expiry date when capped and stored at 2oC – 8oC
- Open vial stability of 28 days at 2oC – 8oC
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Ethanol Calibrator/Control Set | 4 x 10ml | 1 | DA2703 | |
Analytes
Ethanol
Related Products
Acusera Lipids Linearity Verifier
Our Lipids Linearity Verifier comprises 3 common lipid assays and is specifically designed for use on Beckman Coulter
analysers. Five levels are available spanning the instrument’s complete reportable range. Designed in a liquid frozen format,
this linearity verifier will objectively verify calibration of the instrument whilst remaining convenient and easy to use.
Features & Benefits
- Convenient, liquid frozen format
- 5 levels provided
- 14 day stability when stored at 2ºC to 8ºC
- Shelf life of up to 2 years from date of manufacture
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Acusera Lipids Linearity Verifier | 5 x 3mL | 3 | LV10364 | |
Analytes
- HDL Cholesterol
- LDL Cholesterol
- Triglycerides
Acusera Apolipoprotein A-1 (Apo A-1) & Apolipoprotein B (Apo B) Linearity Verifier
Dedicated Linearity Verifier for measuring Apo A-1 and Apo B on Beckman Coulter analysers. Spanning 5 levels designed to
challenge the instruments reportable range, this verifier will objectively verify calibration of the instrument whilst remaining
convenient to use.
Features & Benefits
- Convenient, liquid frozen format
- 5 levels provided
- 14 day stability when stored at 2ºC to 8ºC
- Shelf life of up to 2 years from date of manufacture
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Acusera Apolipoproteins Linearity Verifier | 5 x 3mL | 2 | LV10363 | |
Analytes
- Apolipoprotein A-1 (Apo A-1)
- Apolipoprotein B (Apo B)
Acusera CO2 & Electrolytes Linearity Verifier
Dedicated Linearity Verifier for the measurement of CO2 and electrolytes on Roche Cobas analysers. This verifier is supplied in a liquid ready-to-use format and can be used to objectively verify calibration of the instrument. Five levels are available spanning the instrument’s complete reportable range.
Features & Benefits
- Convenient, liquid ready-to-use format
- 5 levels provided
- 7 day stability when stored at 2ºC to 8ºC
- Shelf life of up to 2 years from date of manufacture
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Acusera CO2 and Electrolytes Linearity Verifier | 5 x 5mL | 4 | LV10362 | |
Analytes
- CO2
- Sodium
- Potassium
- Chloride
Acusera Therapeutic Drug Monitoring (TDM) Linearity Verifier
Our Therapeutic Drug Monitoring (TDM) Linearity Verifier comprises 16 commonly tested drugs in a single vial. Dedicated for use on Roche Cobas systems, and available in a liquid frozen format, this verifier is convenient and easy to use. Five levels span the instrument’s entire reportable range.
Features & Benefits
- Convenient, liquid frozen format
- 5 levels provided
- 14 day stability when stored at 2ºC to 8ºC
- Shelf life of up to 2 years from date of manufacture
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Acusera Therapeutic Drug Monitoring Linearity Verifier | 5 x 5mL | 16 | LV10355 | |
Analytes
- Acetaminophen
- Amikacin
- Carbamazepine
- Digoxin
- Gentamicin
- Lithium
- N-Acetylprocainamide
- Phenobarbital
- Phenytoin
- Procainamide
- Quinidine
- Salicylate
- Theophylline
- Tobramycin
- Valproic Acid
- Vancomycin
