Cytokine Testing Solutions

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Cytokine Testing Solutions

COVID-19 Risk Stratification and Treatment Monitoring

Randox offer testing solutions for a comprehensive range of cytokines, cytokine receptors and growth factors designed to assist with COVID-19 risk stratification, monitoring of treatment efficacy and recovery. Utilising patented Biochip technology up to 12 cytokines and growth factors may be detected simultaneously from a single patient sample.

Cytokines play a vital role in the immune system and are known to be involved in the body’s response to a variety of inflammatory and infectious diseases. The over stimulation of these cytokines in response to infection is referred to as a ‘cytokine storm’ and strongly correlates with poor disease outcomes.

Cytokine storms are a common complication of SARS-CoV-2 (COVID-19) infection triggering viral sepsis, where viral replication and excessive, uncontrolled systemic inflammation may lead to pneumonitis, Acute Respiratory Distress Syndrome (ARDS), respiratory failure, shock, multiple organ failure, secondary bacterial pneumonia, and potentially death.

Why Choose Randox Cytokine Arrays?

  • Simultaneous detection of up to 12 cytokines and growth factors from a single patient sample
  • Fully automated and semi-automated solutions available to suit all laboratory throughputs
  • Comprehensive test menu comprising 26 cytokines, cytokine receptors and growth factors
  • Suitable for use with serum and plasma samples
  • Excellent analytical performance
  • Availability of complementary quality controls for a complete testing package

Cytokine Array I

Analytes
  • Interleukin-1 Alpha (IL-1α)
  • Interleukin-1 Beta (IL-1β)
  • Interleukin-2 (IL-2)
  • Interleukin-4 (IL-4)
  • Interleukin-6 (IL-6)
  • Interleukin-8 (IL-8)
  • Interleukin-10 (IL-10)
  • Interferon Gamma (IFNγ)
  • Epidermal Growth Factor (EGF)
  • Monocyte Chemotactic Protein (MCP-1)
  • Tumour Necrosis Factor Alpha (TNFα)
  • Vascular Endothelial Growth Factor (VEGF)

Ordering Information

Cat. NumberDescriptionKit Size
EV3508Cytokine Array I Evidence360 Biochips
EV3544Cytokine Array I Evidence180 Biochips
EV3513Cytokine Array I Evidence Investigator54 Biochips
EV3623Cytokine Array I High Sensitivity Evidence Investigator54 Biochips

Cytokine Array III

Analytes
  • Interleukin-5 (IL-5)
  • Interleukin-15 (IL-15)
  • Granulocyte Macrophage
  • Colony Stimulating Factor (GM-CSF)
  • Macrophage Inflammatory Protein-1 Alpha (MIP-1 α)
Cat. NumberDescriptionKit Size
EV3680Cytokine Array III Evidence180 Biochips
EV3678Cytokine Array III Evidence Investigator54 Biochips

Cytokine Array IV

Analytes
  • Matrix Metalloproteinase-9 (MMP-9)
  • Soluble Interleukin-2 Receptor Alpha (sIL-2Rα)
  • Soluble Interleukin-6 Receptor (sIL-6R)
  • Soluble Tumour Necrosis Factor I (sTNFR I)
  • Soluble Tumour Necrosis Factor II (sTNFR II)
Cat. NumberDescriptionKit Size
EV3659Cytokine Array IV Evidence180 Biochips
EV3661Cytokine Array IV Evidence Investigator54 Biochips

Cytokine Array IV

Analytes
  • Interleukin -3 (IL-3)
  • Interleukin-7 (IL-7)
  • Interleukin-12 p70 (IL-12p70)
  • Interleukin-13 (IL-13)
  • Interleukin-23 (IL-23)
Cat. NumberDescriptionKit Size
EV3666Cytokine Array V Evidence Investigator54 Biochips

Evidence Investigator

The Evidence Investigator is a benchtop, semi-automated analyser capable of screening 54 patient samples and up to 44 analytes simultaneously using Randox Biochip technology. Ideal for medium to high throughput testing, the Evidence Investigator test menu comprises immunoassay testing and molecular diagnostics on a single platform. Find out More

Evidence

Evidence is a fully automated analyser utilising Randox Biochip technology to screen up to 88 patient samples and up to 44 analytes simultaneously for complete patient profiling. Our comprehensive test menu comprises cytokines, endocrines, tumour markers, thyroid hormones, adhesion molecules and drugs of abuse. Find out More


Bilirubin Linearity Verifier

Therapeutic Drug Quality Control

Our Bilirubin verifier contains both Direct Bilirubin and Total Bilirubin so testing is fully covered. Dedicated for use on Roche
Cobas systems, this verifier spans five levels ensuring the instruments entire reportable range is measured.

Features & Benefits

  • Lyophilised for enhanced stability
  • 5 levels provided
  • Open vial stability of 10 days at 2ºC to 8ºC
  • Shelf life of up to 2 years from date of manufacture
DescriptionSizeAnalytesCat No 
Acusera Enzyme Linearity Verifier5 x 3mL10LV10366

Analytes

  • Direct Bilirubin
  • Total Bilirubin

Enzyme Linearity Verifier

Therapeutic Drug Quality Control

Our Enzyme Linearity Verifier contains 10 commonly tested enzymes in one unique multi-marker verifier allowing you to
consolidate testing. Spanning 5 clinical levels, this verifier ensures the systems entire reportable range is measured. Designed
specifically for use with Roche Cobas systems, our Verifier is available in a convenient liquid frozen format.

Features & Benefits

  • Convenient, liquid frozen format
  • 5 levels provided
  • 14 day stability when stored at 2ºC to 8ºC
  • Shelf life of up to 2 years from date of manufacture
DescriptionSizeAnalytesCat No 
Acusera Enzyme Linearity Verifier5 x 3mL10LV10366

Analytes

  • ALT
  • ALP
  • a-Amylase
  • Pancreatic Anylase
  • AST
  • CK
  • CKMB
  • yGT
  • LDH
  • Lipase

Clinical Chemistry Linearity Verifier

Therapeutic Drug Quality Control

Our Clinical Chemistry Linearity Verifier comprises 17 common chemistry assays, supplied in a liquid frozen format. Designed specifically for use on Roche Cobus analysers, this verifier spans five levels ensuring the instruments entire reportable range is measured.

Features & Benefits

  • Convenient, liquid frozen format
  • 5 levels provided
  • 7 day stability when stored at 2ºC to 8ºC
  • Shelf life of up to 2 years from date of manufacture
DescriptionSizeAnalytesCat No 
Acusera Verify Clinical Chemistry Linearity Verifier5 x 5mL17LV10390

Analytes

  • Albumin
  • BUN
  • Calcium
  • Chloride
  • Creatinine
  • Glucose
  • Iron
  • Lactate
  • Lithium
  • Magnesium
  • Phosphate
  • Potassium
  • Sodium
  • Total Protein
  • Triglycerides
  • Uric Acid
  • Total Cholesterol

RIQAS Point of Care

RIQAS Point of Care EQA Logo

Randox International Quality Assessment Scheme – RIQAS at the Point of Care

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Designed to improve the quality of Point of Care Testing (POCT) in locations such as pharmacies, GP surgeries, hospital out patient departments, sports clinics, supermarkets, diagnostic/treatment and walk-in centres, RIQAS Point of Care provides independent evidence of the accuracy and reliability of test results. Randox International Quality Assessment Scheme (RIQAS) is the world’s largest EQA scheme with over 47,000 participants in more than 139 countries.

Why RIQAS Point of Care?

About RIQAS Point of Care

  • How it Works

    On a monthly basis we will distribute an identical sample of blood to all participating sites.  Each participating site will test the sample in the same way they would test a real patient sample, then return their test results to RIQAS within a set time. The scheme is unique in distributing whole blood samples rather than serum based samples, this ensures that samples act identically to real patient samples at the point of care.

    An electronic report is then sent to participants, comparing their results with other participants using the same analyser.  Satisfactory and unsatisfactory performance is represented using a traffic light system, allowing instant identification of any issues. A more detailed breakdown of performance may be obtained if further information is required. With time, an overall picture will emerge showing whether results are consistently accurate and reliable or whether there may be an underlying analyser and/or operator issue.

    RIQAS Point of Care - How it works
  • Tests and Analysers

    Test Role
    HbA1c • Diagnosing diabetes mellitus
    • Monitoring treatment
    • Encouraging self-management
    Total Cholesterol & HDL Cholesterol • Risk factors for heart disease
    • Monitoring lipid lowering therapy
    C-Reactive Protein (CRP) • Early detection of infectious disease
    • Identifying need for antibiotic treatment
    Glucose • Diagnose and monitor diabetes
    • Monitor for the presence of hypoglycaemia
    (low blood glucose) and hyperglycaemia (high blood glucose)
    International Normalised Ratio (INR) • Used to measure the effect of anticoagulant
    drugs such as warfarin
    • Help diagnose a bleeding disorder; to help
    estimate the severity of liver disease
    Ketones • To determine whether excessive ketones are
    present in the blood, to detect diabetic
    ketoacidosis (DKA)
    Note – The RIQAS Point of Care range is constantly expanding to include new tests and analysers. Please contact us if your desired analyser or test is not currently displayed.
  • Ordering Information

    Panel Catalogue Number
    Lipids RQ9181/A
    Lipids + 1 panel RQ9181/B
    Lipids + 2 panels RQ9181/C
    Additional Sample RQ9181/D
  • What Participants Say

    Our unrivalled commitment to quality and service ensures high levels of customer satisfaction, this is evident from the responses to our latest customer satisfaction survey:

    “All in all a quick and efficient service”
    “Good online system”
    “Very helpful team”
    “Excellent training”
    “They are an experienced team”
    “Very satisfied with the service that we receive”
    “Very good value for money”
    “The website is great”
  • Distribution Dates

    Distribution Month Sample Distributed Result Submission Deadline
    March 2020 2nd March 11th March
    April 2020 6th April 15th April
    May 2020 4th May 13th May
    June 2020 1st June 10th June
    July 2020 6th July 15th July
    August 2020 3rd August 12th August
    September 2020 7th September 16th September
    October 2020 5th October 14th October
    November 2020 2nd November 11th November
    December 2020 7th December 16th December
  • Importance of Quality Assurance

    Quality assurance is an essential aspect of any clinical/diagnostic testing service and is aimed at ensuring the accuracy and reliability of patients’ results. The right result allows the right clinical advice to be offered in a timely manner. Quality assurance operates at two levels:

    Internal Quality Control

    Internal Quality Control includes operator training/ competency assessment, analyser/ test system maintenance, and adherence to policies/ processes. Whilst some point of care analysers include inbuilt quality checks, cross-check analysis against samples with known levels provides immediate assurance and evidence that a patient’s result is safe to report.

    External Quality Assessment

    External Quality Assessment involves analysis of samples with unknown levels that have been distributed by an external organisation. Participants are informed how their results compare with other participants, hence providing independent evidence of performance. Increasingly, participation in an external quality assessment scheme is becoming a mandatory requirement where health and healthcare services are being provided.

    EQA provides assurance to both staff and customers that testing provides accurate and reliable results.

    Want to know more?

    Visit our Importance of EQA page to learn more.

Want to know more?

Contact us or download the RIQAS Point of Care catalogue to learn more.

Continue Reading

Frequently Asked Questions

RIQAS

Contact Us


Ethanol Calibrator/Control Set

Therapeutic Drug Quality Control

Dedicated calibrator and control set designed for the calibration and quality control of the Randox Ethanol assay.

Features & Benefits

  • Liquid ready-to-use
  • Human urine
  • Stable to expiry date when capped and stored at 2oC – 8oC
  • Open vial stability of 28 days at 2oC – 8oC
DescriptionSizeAnalytesCat No  
Ethanol Calibrator/Control Set4 x 10ml1DA2703

Analytes

Ethanol


Acusera Lipids Linearity Verifier

Therapeutic Drug Quality Control

Our Lipids Linearity Verifier comprises 3 common lipid assays and is specifically designed for use on Beckman Coulter
analysers. Five levels are available spanning the instrument’s complete reportable range. Designed in a liquid frozen format,
this linearity verifier will objectively verify calibration of the instrument whilst remaining convenient and easy to use.

Features & Benefits

  • Convenient, liquid frozen format
  • 5 levels provided
  • 14 day stability when stored at 2ºC to 8ºC
  • Shelf life of up to 2 years from date of manufacture
DescriptionSizeAnalytesCat No 
Acusera Lipids Linearity Verifier5 x 3mL3LV10364

Analytes

  • HDL Cholesterol
  • LDL Cholesterol
  • Triglycerides

Acusera Apolipoprotein A-1 (Apo A-1) & Apolipoprotein B (Apo B) Linearity Verifier

Therapeutic Drug Quality Control

Dedicated Linearity Verifier for measuring Apo A-1 and Apo B on Beckman Coulter analysers. Spanning 5 levels designed to
challenge the instruments reportable range, this verifier will objectively verify calibration of the instrument whilst remaining
convenient to use.

Features & Benefits

  • Convenient, liquid frozen format
  • 5 levels provided
  • 14 day stability when stored at 2ºC to 8ºC
  • Shelf life of up to 2 years from date of manufacture
DescriptionSizeAnalytesCat No 
Acusera Apolipoproteins Linearity Verifier5 x 3mL2LV10363

Analytes

  • Apolipoprotein A-1 (Apo A-1)
  • Apolipoprotein B (Apo B)

Acusera CO2 & Electrolytes Linearity Verifier

Therapeutic Drug Quality Control

Dedicated Linearity Verifier for the measurement of CO2 and electrolytes on Roche Cobas analysers. This verifier is supplied in a liquid ready-to-use format and can be used to objectively verify calibration of the instrument. Five levels are available spanning the instrument’s complete reportable range.

Features & Benefits

  • Convenient, liquid ready-to-use format
  • 5 levels provided
  • 7 day stability when stored at 2ºC to 8ºC
  • Shelf life of up to 2 years from date of manufacture
DescriptionSizeAnalytesCat No 
Acusera CO2 and Electrolytes Linearity Verifier5 x 5mL4LV10362

Analytes

  • CO2
  • Sodium
  • Potassium
  • Chloride

Acusera Therapeutic Drug Monitoring (TDM) Linearity Verifier

Therapeutic Drug Quality Control

Our Therapeutic Drug Monitoring (TDM) Linearity Verifier comprises 16 commonly tested drugs in a single vial. Dedicated for use on Roche Cobas systems, and available in a liquid frozen format, this verifier is convenient and easy to use. Five levels span the instrument’s entire reportable range.

Features & Benefits

  • Convenient, liquid frozen format
  • 5 levels provided
  • 14 day stability when stored at 2ºC to 8ºC
  • Shelf life of up to 2 years from date of manufacture
DescriptionSizeAnalytesCat No 
Acusera Therapeutic Drug Monitoring Linearity Verifier5 x 5mL16LV10355

Analytes

  • Acetaminophen
  • Amikacin
  • Carbamazepine
  • Digoxin
  • Gentamicin
  • Lithium
  • N-Acetylprocainamide
  • Phenobarbital
  • Phenytoin
  • Procainamide
  • Quinidine
  • Salicylate
  • Theophylline
  • Tobramycin
  • Valproic Acid
  • Vancomycin

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