Non-Esterified Fatty Acids (NEFA) Assay

Home - Reagents - Page 7

Non-Esterified Fatty Acids (NEFA) Assay

Reagent | Non-Esterified Fatty Acid (NEFA)

Non-Esterified Fatty Acid (NEFA): A Marker of Insulin Resistance

Benefits of the Randox NEFA Assay

Exceptional correlation

A correlation coefficient of r=0.98 was displayed when the Randox NEFA assay was compared to commercially available methods.

Applications available

Applications available detailing instrument-specific settings for the convenient use of the Randox NEFA assay on a variety of clinical chemistry analsyers.

Extensive measuring range

The Randox NEFA assay has a measuring range of 0.072 – 2.24mmol/l for the comfortable detection of clinically important results.

Standard supplied with the kit

The Randox NEFA kit includes the standard simplifying the ordering process.

Controls available

Controls available offering a complete testing package.

Excellent precision

The Randox NEFA assay displayed a precision of <5% CV.

Ordering information

  • Ordering Information
Cat NoSize
FA115R1 3 x 10ml (C)
R2 3 x 20ml
EnquireKit Insert RequestMSDSBuy Online
(C) Indicates calibrator included in kit

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

  • PHYSIOLOGICAL SIGNIFICANCE
  • Clinical Significance

Non-esterified fatty acids are important metabolites stored in adipose tissue. NEFA turnover is swift, with a plasma half – life of 2 to 4 minutes. The dominant source of NEFA is abdominal subcutaneous fat, with considerably less found in leg adipose tissue and a small proportion found in the intraabdominal adipose tissue. NEFA has been recognised as a vehicle by which triacylglycerol (TG) (stored in the adipose tissue) is transported to its sites of utilisation 1. NEFA has been identified as the major source for skeletal muscle during fasting stages and long periods between meals. Cross – sectional studies have consistently documented that circulating NEFA levels are proportional to body fat storage and demonstrated positive correlations between fasting NEFA levels and obesity, insulin resistance and glucose tolerance 2.

Non-esterified fatty acids concentrations are strongly associated with insulin resistance. In the fasting state, the resistance of adipose tissue to the antilipolytic effect of insulin causes the extensive release of NEFA into circulation. Consequently, elevated NEFA levels exacerbate insulin resistance through diminishing insulin – stimulated glucose intake into the skeletal muscle, directly affecting insulin signalling 3.

Useful Links

Clinical Chemistry Controls

Clinical Chemistry EQA

A-Z Reagents


Urinary Protein

Reagent | Urinary Protein

Key Benefits

Applications available

For a wide variety of clinical chemistry analysers including the RX series

Strong correlation

The Urinary Protein assay showed a correlation coefficient of 0.9998 against another commercially available method

Standard included in kit

Simplifying the ordering process

Randox Urinary Protein (Colorimetric)

  • Colorimetric method
  • Liquid ready-to-use reagents
  • Stable to expiry date when stored at +15 to +25⁰C
  • Applications available
Cat NoSize
UP15703 x 100ml (S)(L)EnquireKit Insert RequestMSDSBuy Online
UP81134 x 20ml (S)(L)EnquireKit Insert RequestMSDSBuy Online
(L) Indicates liquid option
(S) Indicates standard included in kit

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is Urinary Protein assay used for?

Determination of Total Protein in urine and cerebrospinal fluid is valuable in the diagnosis of renal and central nervous system disorders respectively. Urinary protein elevations are commonly seen in the following conditions: strenuous exercise, fever and hypothermia, nephrosis and diabetic nephropathy and urinary tract infections. Determination of total protein in cerebrospinal fluid aids in the diagnosis of such conditions as meningitis, CNS tumours and cerebral haemorrhage.

Publications


    Related Products

    Veterinary Panel

    For more information or to view more reagents within the veterinary panel, please click here


    Uric Acid

    Reagent | Uric Acid

    Key Benefits

    Applications available

    For a wide variety of clinical chemistry analysers including the RX series

    Strong correlation

    The Uric Acid assay showed a correlation coefficient of 0.99 against another commercially available method

    Excellent stability

    The Uric Acid assay has a precision of less than 4% CV

    Randox Uric Acid

    • Enzymatic Colorimetric method
    • Liquid and lyophilised reagents available
    • Stable to expiry date when stored unopened protected from light
    • Applications available
    Cat NoSize
    UA2306 x 15ml (S)EnquireKit Insert RequestMSDSBuy Online
    UA3824R1 6 x 51ml (L)
    R2 4 x 20ml
    EnquireKit Insert RequestMSDSBuy Online
    UA38709 x 51ml (L)EnquireKit Insert RequestMSDSBuy Online
    UA8069R1 6 x 56ml (L)
    R2 6 x 20ml
    EnquireKit Insert RequestMSDSBuy Online
    UA8333R1 4 x 20ml (L)
    R2 4 x 7ml
    EnquireKit Insert RequestMSDSBuy Online
    (L) Indicates liquid option (S) Indicates standard included in kit

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    What is Uric Acid assay used for?

    Uric acid measurements are used in the diagnosis and treatment of numerous renal and metabolic disorders including renal failure, gout, leukemia and psoriasis. Uric acid is a potent antioxidant contributing to around half the antioxidant capacity of blood plasma. It is a scavenging antioxidant that acts by inactivating free radicals such as HO and HOCI.

    Antioxidant Panel

    For more information or to view more reagents within the antioxidant panel, please click here

    Clinical Chemistry Panel

    For more information or to view more reagents within the clinical chemistry panel, please click here


    Urea

    Reagents | Urea

    Key Benefits

    Applications available

    For a wide variety of clinical chemistry analysers including the RX series

    Strong correlation

    The Urea assay showed a correlation coefficient of 0.9935 against another commercially available method

    Liquid and Lyophilised reagents available

    Randox Urea assays are available in liquid ready-to-use and lyophilised formats, offering greater consumer choice

     

    Randox Urea (Kinetic)

    • Kinetic method
    • Lyophilised reagents
    • Stable for 4 weeks at +2 to +9oC or 2 days at +15 to +25oC
    • Measuring range linear to 50mmol/l in serum or plasma, and 1050mmol/l in urine.
    • Applications available

     

     

    Cat NoSize
    UR446
    10 x 50ml (S)
    1 minute read
    EnquireKit Insert RequestMSDSBuy Online
    (L) Indicates liquid option (S) Indicates standard included in kit

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    Randox Urea (Berthelot)

    • Berthelot method
    • Liquid ready-to-use reagents
    • Working reagent stable for 2 months at +2 to +8oC
    • Measuring range 1.59-40 mmol/l in serum and plasma
    • Applications available
    Cat NoSize
    UR1068170ml (S)
    Manual use only
    EnquireKit Insert RequestMSDSBuy Online
    (S) Indicates standard included in kit

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    Randox Urea (Enzymatic Kinetic)

    • Enzymatic Kinetic method
    • Liquid ready-to-use reagents
    • Stable to expiry when stored at 2-8oC
    • Applications available
    Cat NoSize
    UR3825R1 6 x 51ml (L)
    R2 4 x 20ml
    EnquireKit Insert RequestMSDSBuy Online
    UR9781R1 6 x 68ml
    R2 6 x 44ml
    EnquireKit Insert RequestMSDSBuy Online
    UR8334R1 4 x 20ml
    R2 4 x 7ml
    EnquireKit Insert RequestMSDSBuy Online
    UR8070R1 6 x 56ml (L)
    R2 6 x 20ml
    EnquireKit Insert RequestMSDSBuy Online
    (L) Indicates liquid option

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    What is Urea assay used for?

    Urea is synthesized in the liver from ammonia, as a result of deamination of amino acids. This biosynthetic pathway is the chief means of excretion of surplus nitrogen by the body. Measurements obtained by this test are used in the diagnosis of renal and metabolic disorders, most frequently kidney disorders. More than 60% of the kidney must be destroyed before plasma urea levels are significantly raised. This test is most frequently used in conjunction with serum creatinine for increased protein levels (cardiac decompensation, water depletion).

    • Sánchez-Rodríguez, M.A., et al Antioxidant capacity in relationship to serum lipid peroxides levels in healthy elderly of Mexico City. 2004, 38(2): 193-198.
    • Wathes, D.C., et al Differences between primiparous and multiparous dairy cows in the inter-relationships between metabolic traits, milk yield and body condition score in the periparturient period. Domestic Animal Endocrinology. 2007, 33(2): 203-225.
    • Badiou. S., et al. Fine-tuning of the prediction of mortality in hemodialysis patients by use of cytokine proteomic determination.Clin. J. Am. Soc. Nephrol. . 2006, 3: 423-430.
    • Rhodes, P., et al. Adult-onset obesity reveals prenatal programming of glucose-insulin sensitivity in male sheep nutrient restricted during late gestation. PloS ONE 2009, 4(10): e7393.

    Clinical Chemistry Panel

    For more information or to view more reagents within the clinical chemistry panel, please click here

    Veterinary Panel

    For more information or to view more reagents within the veterinary panel, please click here

    Stay up-to-date with the latest Randox Reagents news & events


    Total Protein

    Reagent | Total Protein

    Key Benefits

    Excellent precision

    The Total Protein assay has a precision of less than 3% CV

    Applications available

    For a wide variety of clinical chemistry analysers including the RX series

    Exceptional correlation

    The Total Protein assay showed a correlation coefficient of 1.00 against another commercially available method

    Randox Total Protein (Biuret)

    • Biuret method
    • Liquid reagents
    • Stable to expiry at 15-25⁰C
    • Applications available
    Cat NoSize
    TP2452 x 500ml (S)(L)EnquireKit Insert RequestMSDSBuy Online
    TP38699 x 51ml (L)EnquireKit Insert RequestMSDSBuy Online
    TP4001R1 4 x 51ml (L)
    R2 4 x 44ml
    EnquireKit Insert RequestMSDSBuy Online
    TP8066R1 4 x 68ml (L)
    R2 4 x 68ml
    EnquireKit Insert RequestMSDSBuy Online
    TP8336R1 4 x 20ml (L)
    R2 4 x 17ml
    EnquireKit Insert RequestMSDSBuy Online
    (L) Indicates liquid option
    (S) Indicates standard included in kit

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    What is Total Protein assay used for?

    Total Protein measurements obtained by the Biuret method are used in the diagnosis and treatment of a variety of diseases involving the liver, kidney and bone marrow as well as other metabolic or nutritional disorders.

    • McGrath L.T., et al. Increased oxidative stress in Alzheimer’s disease as assessed with 4-hydroxynonenal but not malondialdehyde. Q J Med. 2001, 94: 485-490
    • Mula-Abed, W-A. S. and Hanna, B.E. Measurement of serum fructosamine as an index of glycated protein in patients with nephrotic syndrome and chronic liver diseases. Bahrain Medical Bulletin 2001, 23(4)
    • Nishina, H., et al. Effect of nutritional restriction in early pregnancy on isolated femoral artery function in mid-gestation fetal sheep. J. Physiol. 2003, 553(2): 637-647
    • Ozdemir, D., et al. Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats. Physiol. Res., 2005, 54(6): 631-637
    • Mula-Abed, W-A. S. and Aziz, S.B. Serum fructosamine (glycated protein) and related biochemical parameters during normal pregnancy. JBMS Journal of the Bahrain Medical Society 2006, 18(3): 115-122
    • Saad, S.Y. et al. Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats. Basic Clin. Pharmacol. Toxicol. 2006, 99(6): 412-417
    • Belaïd-Nouira, Y., et al. Study of lipid profile and parieto-temporal lipid peroxidation in AICI3 mediated neurotoxicity. Modulatory effect of fenugreek seeds. Lipids Health Dis. 2012, 11: 16
    • Yakubu, N., et al. Antioxidant and hepatoprotective properties of tofu (curdle soymilk) against acetaminophen-induced live damage rats. Biotech. Res. Int. 2013, ID 230142

    Clinical Chemistry Panel

    For more information or to view more reagents within the clinical chemistry panel, please click here

    Stay up-to-date with the latest Randox Reagents news & events


    Sodium

    Reagent | Sodium


    Key Benefits

    Exceptional correlation

    The Sodium assay showed a correlation of r=0.98 against another commercially available method

    Applications available

    For a wide variety of clinical chemistry analysers including the RX series

    Excellent stability

    Working reagent stable for 2 weeks at 2-8°C or 5 days at 15-25°C

    Randox Sodium (Enzymatic)

    • Enzymatic method
    • Lyophilised reagents
    • Working reagent stable for 2 weeks at 2-8°C or 5 days at 15-25°C
    Cat NoSize
    NA3851R1 3 x 20ml
    R2 3 x 9ml
    EnquireKit Insert RequestMSDSBuy Online
    NA8327R1 4 x 10ml
    R2 4 x 6ml
    EnquireKit Insert RequestMSDSBuy Online
    (S) Indicates standard included in kit

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    What is Sodium assay used for?

    Sodium measurements are used in the diagnosis and treatment of aldosteronism, diabetes insipidus, adrenal hyper-tension, Addison’s disease, dehydration, inappropriate antidiuretic hormone secretion, or other diseases involving electrolyte imbalance.

    Publications


      Clinical Chemistry Panel

      For more information or to view more reagents within the clinical chemistry panel, please click here

      Veterinary Panel

      For more information or to view more reagents within the veterinary panel, please click here


      Ethanol Reagent

      Reagent | Ethanol

      Key Benefits of Ethanol

      Excellent correlation

      The Randox ethanol assay displayed an excellent correlation coefficient of r=0.995 when compared against the gold standard Gas Chromatography / Mass Spectrometry (GC/MS).

      Dedicated calibrator/control set available

      A dedicated ethanol calibrator/control set is available for a full testing package.

      Applications available

      Applications are available detailing instrument-specific settings for the convenient use of the Randox ethanol assay on a wide range of clinical chemistry analysers.

      Other features of the Ethanol reagent

      • Enzymatic method using NAD and alcohol dehydrogenase
      • Stable to expiry date when stored at +2 to +8°C
      • Wide measuring range of 10 – 500mg/dl
      • Suitable for use with both urine and serum samples

      Ordering Information

      Cat NoSize
      DA4015R1 2 x 16.9ml (L)
      R2 2 x 8ml
      EnquireKit Insert RequestMSDSBuy Online
      (L) Indicates liquid option

      Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

      What is the Ethanol assay used for?

      Ethyl alcohol is present in some drinks, liquors, medicinal preparations and foods. After ethyl alcohol ingestion, the alcohol quickly spreads though the whole body and is mostly metabolised in the liver and excreted. Ethyl alcohol acts as a Central Nervous System depressant, and can lead to loss of alertness, stupor, coma and death and frequently cause public safety issues. Alcohol consumption during pregnancy carries a heavy risk of permanent mental and physical defects in the child, known as fetal alcohol syndrome. Ethyl alcohol measurements are also used in diagnosis and treatment of alcohol intoxication and poisoning.

      Clinical Chemistry Panel

      For more information or to view more reagents within the clinical chemistry panel, please click here


      Fructosamine (Glycated Protein) Assay

      Reagent | Fructosamine (Glycated Protein)

      Offering Improved Specialty and Reliability

      Benefits of the Fructosamine Assay

      Superior Performance

      Superior method

      The Randox enzymatic method offers improved specificity and reliability compared to the conventional NBT-based methods as the enzymatic method does not suffer from non-specific interferences unlike the existing methods which can also be time-consuming and difficult to automate.

      14-C glucose icon

      Standardisation to the highest level

      The Randox dedicated fructosamine calibrator and controls are assigned relative to human serum glycated with 14-C glucose, directly reflecting the nature of the patient sample.

      Logos-09

      Excellent correlation

      A correlation coefficient of r=0.98 was displayed with the Randox fructosamine assay was compared to commercially available methods.

      Logos-06

      Liquid ready-to-use

      The Randox fructosamine assay is available in a liquid ready-to-use format for convenience and ease-of-use.

      Logos-07

      Applications available

      Applications available detailing instrument-specific settings for the convenient use of the Randox fructosamine assay on a variety of clinical chemistry analysers.

      Ordering Information

      Cat NoSize
      FR3133R1 5 x 25ml (L)

      R2 5 x 6.3ml
      EnquireKit Insert RequestMSDSBuy Online
      FR4030R1 4 x 19.8ml (L)

      R2 4 x 6.9ml
      EnquireKit Insert RequestMSDSBuy Online
      (L) Indicates liquid option

      Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

      Diagnostic Uses

      • Clinical Significance
      • Physiological Significance
      • Drawbacks of Traditional Diabetes Tests

      Fructosamine (glycated protein) has been identified as an early indicator of diabetic control compared to other markers such as HbA1c. RBCs live for approximately 120 days, HbA1c represents the average blood glucose levels for the previous 2 to 3 months. Conversely, fructosamine has a shorter lifespan, of about 14 to 21 days, reflecting average blood glucose levels from the previous 2 to 3 weeks 1.

      Fructosamine testing has been identified as being the best for patient care as HbA1c results can be inconclusive for several reasons. Genetic, haematological and disease-related factors negatively impact HbA1c levels, with low levels observed in late stage chronic kidney disease, conditions that shorten the lifespan of erythrocytes such as haemolytic anaemia, and in certain haemoglobinopathies such as sickle cell disease 2.

      In gestational diabetes, fructosamine should be tested as HbA1c levels are difficult to interpret as HbA1c integrates glycaemia over the lifespan of the erythrocyte. Therefore, HbA1c is relatively insensitive to short term changes. Consequently, HbA1c testing isn’t suitable in the monitoring of the effects of changes in medication. Fructosamine is a medium-term marker (shorter life span) and is a much more suitable test 2.

      In a diabetic patient where blood glucose levels are abnormally elevated, the concentration levels of fructosamine also increase as fructosamine is formed by a non-enzymatic Maillard reaction between glucose and amino acid residues of proteins. During this glycation process, an intermediate labile Schiff base is produced which is converted to a more stable ketoamine (fructosamine) via an Amadori rearrangement 3.

      The Fasting Plasma Glucose (FPG) test measures the level of blood sugars which is used to diagnose and monitor diabetes based on insulin function. The main drawback of this test is that a hormone called glucagon, produced in the pancreas, is triggered during prolonged fasting, signalling the liver to release glucose into the bloodstream. In diabetic conditions, either the body is unable to generate enough insulin or cannot appropriately respond to insulin. Consequently, FPG levels remain high 1.

      In the1980’s, HbA1c was incorporated into clinical practice as HbA1c levels correlated well with glycaemic control over a 2 to 3-month period. The main drawback of this test is that any condition that reduces the survival rate of erythrocytes such as haemolytic anaemia will falsely lower the HbA1c test results regardless of the assay method utilised 3.

      Related Products

      Fructosamine Calibrator

      Fructosamine Control

      Clinical Chemistry EQA

      Publications


      Therapeutic Drug Monitoring Reagents

      Therapeutic Drugs

      Therapeutic drugs are used to heal, control, or prevent certain diseases and conditions, and are often required throughout a person’s lifetime to treat chronic conditions.

      Most therapeutic drugs have a narrow therapeutic index and require regular monitoring to ensure correct levels of the drug in the blood are maintained. Therapeutic index refers to the difference in the amount that causes a therapeutic effect, and the amount that causes toxicity.

      Toxic levels may occur as a result of a person’s ability to absorb the drug i.e. change in health, additional medication that may be reacting with the drug, and, overdose. In addition, sub-therapeutic levels may occur where the patient’s level of the drug is inadequate for their treatment.

      • Liquid-ready-to-use reagents for increased convenience
      • Extensive measuring ranges for ultimate detection of ranges outside the therapeutic range
      • Applications for a wide range of analysers to allow flexibility
      • Multi-analyte controls and calibrators to decrease costs
      • Our TDM controls are lyophilised for enhanced stability
      • Latex-enhanced immunoturbidimetric method and a strong correlation to reference methods.

      Therapeutic drugs which may require monitoring include:

      • Carbamazepine, an anti-epileptic drug used in the treatment of seizures; side effects of incorrect dosage can include breathing difficulties, drowsiness and in severe cases seizures, development of lupus and fatal skin reactions
      • Digoxin, a cardiovascular drug used in the treatment of heart conditions such as arrhythmias and heart failure; digoxin toxicity can be associated with health issues such as changes in heart rate and rhythm, gastrointestinal problems and fatigue
      • Phenobarbital, an anti-epileptic drug and sedative-hypnotic drug; incorrect dosage can cause drowsiness, depression, headaches and dizziness with severe cases leading to renal failure, coma and hypotension.
      • Phenytoin, an anti-epileptic drug used to control generalised seizures; incorrect dosage can lead to side effects such as insomnia, nausea, confusion and fatigue, with symptoms of high level toxicity including seizures, unusual bleeding and difficulty breathing or swallowing.
      • Valproic Acid (an anti-epileptic drug); incorrect dosage can result in severe liver impairments, renal function failure and pancreatic function impairments.

      Monitoring Dosage is Key

      Therapeutic drugs are monitored upon initial dosage to evaluate dosage suitability for the individual, as each person absorbs, metabolises and eliminates drugs at different rates. Depending upon test results, drug dosage may be increased or decreased, and monitored until the blood level reaches the therapeutic range.

      Testing

      Testing may be required in situations where a patient is experiencing side effects to determine if the dose needs to be adjusted; if a patient has experienced a change in health i.e. kidney function, thyroid problems, cancer, or stomach or intestinal issues; if a patient begins taking another medication; if a doctor suspects the patient is not taking the recommended dose of medication; and, if an overdose is suspected.

      Email Us

      Get in touch with your local sales representative via email at reagents@randox.com

      Need Instructions?

      Kit Inserts are available to download for free on our online portal

      Buy Online

      Order your cardiology kits today by visiting our online store 


      Specific Proteins

      Specific Protein Reagents: Overview

      The measurement of proteins in the body assist in the diagnosis and evaluation of various conditions. Randox manufacture immunoturbidimetric kits for the study of a wide range of specific proteins including unique products such as Apolipoprotein C-II, Apolipoprotein C-III, Apolipoprotein E, Cystatin C and Microalbumin.

      Download our Reagents Brochure

      Benefits

      • Bio-chemistry automated for rapid, efficient testing
      • Flexibility with applications available for use on a wide range of clinical chemistry analysers
      • Liquid ready-to-use reagents for efficiency
      • Latex enhanced for increased sensitivity
      • Wide measuring ranges, minimising the need to perform repeat tests
      • Minimal interference from haemoglobin, bilirubin, triglycerides and intralipids

      Superior immunoturbidimetry methodology

      Immunoturbidimetry has become the main method for performing protein tests over recent years; this development is in light of the comparability and flexibility of immunoturbidimetric testing when compared to traditional nephelometric testing. Both methods measure the turbidity of a sample to determine the level of analyte; the difference is that immunoturbidimetric tests measure the absorbance of light by the sample whereas nephelometric tests measure the light scattered at a fixed angle.

      The move from nephelometric testing to immunoturbidimetric testing provides numerous advantages, most notably they offer lower laboratory costs; nephelometry requires the use of dedicated instruments known as Nephelometers, which are slow, have high consumable costs, require highly trained personnel, and are not able to perform any other type of assay.

      Immunoturbidimetric tests, on the other hand, are carried out on routine clinical analysers, thus offering test consolidation; consolidation of tests on one single platform offers improved laboratory efficiency, versatility, rapid testing and cost-savings.

      Randox unique specific protein assays

      Apolipoprotein C-II, for use in the assessment of CVD;  Apo C-II is an amino acid protein synthesised mainly in the liver, of which deficiency can lead to increased risk of coronary artery disease, chylomicronemia, xanthomas and recurrent pancreatitis. Randox Apo C-II produces truly accurate results with excellent sensitivity of 1.48mg/dl and limited interference from Bilirubin, Haemoglobin, Intralipid and Triglycerides

      Apolipoprotein C-III, an emerging risk factor of CVD; Apo C-III is an amino acid protein which circulates in plasma in association with triglyceride rich lipoproteins and HDL, of which elevated levels are associated with primary and secondary hypertriglyceridemia, type 2 diabetes, hyperbilirubinemia, deficient kidneys and decreased thyroid function. Randox Apo C-III guarantees results with excellent linearity of 21.7mg/dl and limited interference from Bilirubin, Haemoglobin, Intralipid and Triglycerides

      Apolipoprotein E, for identification of CVD; Apo E is amino acid protein synthesised mainly in the liver, in addition to the brain, spleen, lungs, adrenals, ovaries, kidneys, muscle cells and in macrophages. Apo E deficiency can lead to premature atherosclerosis. Randox Apo E has an excellent measuring range of 1.04-12.3 mg/dl and therefore can comfortably detect abnormal Apo E levels

      Cystatin C, a specific and sensitive biomarker of renal dysfunction; Cystatin C is a protein removed and broken down by the kidneys and is considered the most effective marker for detecting kidney disease in infants and in the elderly. This is because it is highly sensitive to small changes in the GFR (Glomerular Filtration Rate); the rate at which glomeruli in the kidney filters impurities from the blood. Randox Cystatin C is suitable for use with serum and plasma samples, and has a wide measuring range able to comfortably detect abnormal levels. With on-board stability of 28 days at 10°C it also reduces reagent wastage

      Microalbumin, used to detect very small levels of albumin in the urine; low albumin concentrations in urine are the earliest marker of renal damage and therefore the Microalbumin test enables preventative measures to be taken. Randox Microalbumin immunoturbidimetric test enables sensitive and accurate assessment of albumin levels with excellent sensitivity of 5.11 mg/l to ensure even low albumin concentrations are detected.

      Email Us

      Get in touch with your local sales representative via email at reagents@randox.com

      Need Instructions?

      Kit Inserts are available to download for free on our online portal

      Buy Online

      Order your cardiology kits today by visiting our online store 


      Request a meeting
      ×
      Make an Enquiry - RX series
      ×
      Make an Enquiry - Reagents
      ×
      Kit Insert Request - Reagents