Reagent | Total Antioxidant Status (TAS)
A Marker of Overall Antioxidant Status
Benefits of the Randox TAS Assay
The Randox TAS assay utilises the colorimetric method, offering convenience and efficiency in comparison to ELISA technology and produces results in as little as 3 minutes.
Excellent measuring range
The Randox TAS assay is linear up to 2.50mmol/l enabling the comfortable detection of clinically important results.
Lyophilised reagents offer enhanced stability, reducing wastage.
Standard supplied with the kit
The standard is supplied with the TAS kit, simplifying the ordering process.
Dedicated TAS control available
Dedicated TAS control available offering a complete testing package.
Applications available detailing instrument-specific settings for the convenient use of the Randox TAS assay on a variety of clinical chemistry analsyers.
|NX2332||5 x 10ml (S)||Enquire||Kit Insert Request||MSDS||Buy Online|
|(S) Indicates standard included in kit|
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
Free radicals / reactive oxygen species (ROS) are produced during normal cellular metabolism, however, can have harmful effects. Antioxidants are the first line of defence and are produced by the body to neutralise the harmful effects of ROS, preventing cellular damage 1,2, 3. Measuring total antioxidant status (TAS) can provide information on an individual’s overall antioxidant status, which may include antioxidants not yet recognised or not easily measured. The TAS of a sample is a quantitative measurement of the state of balance of the various components (exerting actions in different way) under specified reaction conditions 4.
Reduced levels of total antioxidant status (TAS) is indicative of oxidative stress and increased susceptibility to oxidative damage 5. Oxidative stress is an imbalance between the ROS and antioxidants in the body, favouring ROS 6. Oxidative stress is associated with several health conditions, including: chronic inflammation, neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease, cancer and CVD 7.
 Kattappagari KK, Teja CSR, Kommalapati RK, Poosarla C, Gontu SR, et al. Role of antioxidants in facilitating the body functions: A review. Journal of Orofacial Sciences 2015; 7(2): 71-75.
 Bendich A. Physiological role of antioxidants in the immune system. Journal of Dairy Science 1993; 76(9): 2789-1794.
 Young IS, Woodside JV. Antioxidants in health and disease. Journal of Clinical Pathology 2001; 54(3): 176-186.
 Lamont J, Campbell J, FitzGerald P. Measurement of Individual vs Total Antioxidants. Clinical Chemistry 1997; 43(5): 852-854.
 Young IS. Measurement of total antioxidant capacity. Journal of Clinical Pathology 2001; 54(5): 339.
 Dix M. Everything You Should Know About Oxidative Stress. https://www.healthline.com/health/oxidative-stress (accessed 27 February 2020).
 Eske J. How does oxidative stress affect the body? https://www.medicalnewstoday.com/articles/324863 (accessed 27 February 2020).