Stable on board the analyser for 28 days at 10⁰C which minimises reagents waste
Standardised to NIST SRM 1955 (Homocysteine Standard Reference Material) which shows excellent correlation with industry comparative methods
Wide measuring range
1.7 – 47.9 μmol/L. The normal range for homocysteine is 5-20μmol/L therefore the Randox assay is capable of detecting abnormal levels of homocysteine within a sample
- Enzymatic method
- Convenient two part liquid ready-to-use reagents
- Stable on board the analyser for 28 days at 10⁰C
- Measuring range 1.7-47.9 µmol/L
- Two levels of standard included in the kit
- Limited interference from bilirubin, haemoglobin, intralipid and triglycerides
- Suitable for both human serum and plasma (Li Hep or K EDTA samples)
What is Homocysteine assay used for?
Hyperhomocysteinemia, elevated levels of homocysteine, can be associated with an increased risk of CVD. Patients with chronic renal disease experience an excess morbidity and mortality due to arteriosclerotic CVD. Elevated concentration of homocysteine is a frequently observed finding in the blood of these patients. Although such patients lack some of the vitamins involved in the metabolism of homocysteine, the elevated homocysteine levels are mainly due to impaired homocysteine removal from the blood by the kidneys.
Recent evidence has also implicated elevated blood levels of homocysteine in miscarriages and birth defects. Drugs such as methotrexate, carbamazepine, phenytoin, nitrous oxide and 6-azauridine triacetate interfere with homocysteine metabolism and may give elevated levels.