Reagent | Anti-Streptolysin O (ASO)

Key benefits of the Anti-Streptolysin O reagent

Excellent correlation to standard methods

The Randox Anti-Streptolysin O assay showed an excellent correlation coefficient of 0.97 compared against other commercially available methods.


Excellent stability

Stable until expiry date when stored at +2 to +8°C


The antiserum of Randox Anti-Streptolysin O is monospecific for human ASO and has not been shown to cross react with other serum proteins.

Liquid ready-to-use

Available in a liquid ready-to-use format for convenience and ease-of-use.

Applications available

Applications available detailing instrument-specific settings for the convenient use of the Randox Anti-Streptolysin O assay on a variety of clinical chemistry analysers.

Ordering information

Cat NoSize
LO3998R1 2 x 9ml (L)
R2 2 x 14ml
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LO8015R1 2 x 8.7ml
R2 2 x 12ml
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LO8305R1 1 x 7.7ml (L)
R2 1 x 11.2ml
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Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is the Anti-Streptolysin O (ASO) assay used for?

What is Anti-Streptolysin O (ASO)?

Streptolysin O (SLO) is a toxic and lethal, exocellular immunogenic protein produced and released in response to Group A Streptococcal pyogenes.  For more information on streptococcal infections, please click here [external link].  The release of SLO stimulates the production of Anti-Streptolysin O (ASO) antibodies to neutralise the SLO’s haemolytic effects. The O in the name stands for oxygen-labile.

What is the Anti-Streptolysin O (ASO) assay used for?

The Anti-Streptolysin (ASO) test is used to determine recent streptococcal infection and post streptococcal complications which includes rheumatic fever and glomerulonephritis. The presence and level of ASO antibodies in human serum directly reflects the extent and degree of infection. Elevated levels of ASO may also be present in other conditions including scarlet fever, acute rheumatoid arthritis, tonsillitis and various other streptococcal infections as well as in health carriers.

The Randox Anti-Streptolysin (ASO) assay is used to measure the presence of anti-streptolysin antibodies in the blood to determine if a strep infection is present.

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