CK-MB Reagent

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Key Benefits of the Randox CK-MB reagent

Liquid and lyophilised reagents available

The Randox CK-MB reagent is available in a liquid ready-to-use or in a lyophilized format offering you convenience and choice when selecting the best choice for your laboratory

Wide measuring range

The Randox CK-MB reagent can comfortably detect levels outside of the healthy range measuring between 9.1 – 2216 U/l.

Excellent stability

Stable until expiry date when stored at +2 to +8°C

Other features of the Randox CK-MB reagent

  • Immunoinhibition UV method
  • Available as liquid and lyophilised reagents Stable until expiry date when stored at +2 to +8°C
  • Stable until expiry date when stored at +2 to +8°C
  • Measuring range 9.1 – 2216 U/l
Cat NoSizeAnalyserEasy Read
Easy Fit
 
(L) Indicates liquid option
CK129619 x 2.5mlGeneral Use--
CK15535 x 20mlGeneral Use--
CK7946R1 6 x 20ml
R2 3 x 10ml
Hitachi 717/911/912/704/902
RX Daytona/Imola


CK9717R1 6 x 21ml
R2 2 x 15ml
Hitachi 917/Mod P
Abbott Architect
Konelab 20i/30i/60i
Beckman Coulter AU Series






CK3813R1 4 x 20ml
R2 4 x 6ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


CK4043R1 4 x 20ml
R2 4 x 6ml (L)
RX Daytona/Imola
Hitachi 717/911/912/704/902


CK8026R1 4 x 20ml
R2 4 x 6ml
RX Suzuka
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








CK8148R1 4 x 20ml (L)
R2 4 x 8ml
RX Modena--

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is the CK-MB assay used for?

What is CK-MB?

Creatine Kinase (CK) is internationally accepted as a sensitive and specific indicator of acute myocardial infarction (AMI). There are 3 major forms of the iso-enzymes of CK, CK-MM, CK-MB and CK-BB. CK-BB is produced by the brain in very small insignificant amounts. CK-MM is produced by the skeletal and heart tissue. CK-MB is produced by the heart muscle and increases when the heart muscle is damaged. For more information on the structure and function of CK isoenzymes in tissue, please click here [external link].

What is the CK-MB assay used for?

CK-MB is a more sensitive marker to myocardial infarction than total CK activity as CK-MB has a lower basal level and a narrower normal range.  In the vast majority of cases the CK-MB activity rises within 4 to 6 hours of an acute infarction.  Between 10 to 24 hours, maximum values are observed. The CK-MB activity generally returns to normal between the third and fourth day post- infarction.

The Randox CK-MB reagent can measure small, but significant changes in CK-MB activity during the early hours following the onset of chest pain.

  • Pal, S. Estimation of CKMB from RIQAS control serum at 37 degree celsius. Indian Journal of Clinical Biochemistry, 2002, 17(2): 88-90
  • Huang, Z-Q., et al. Effects of N-n-butyl haloperidol iodide on rat myocardial ischemia and reperfusion injury and L-type calcium current. Acta Pharmacol. Sin 2003, 24(8): 757-763
  • Mohiti, J., et al. The significance of troponin T and CK-MB release in coronary artery bypass surgery. Indian J. Clin. Biochem.2004, 19(1): 113-117
  • Saad, S.Y., et al. Cardiotoxicity of doxorubicin/paclitaxel combination in rats: effect of sequence and timing of administration. J. Biochem. Mol. Toxicol. 2004, 18(2): 78-86
  • Arya D.S., et al. Pyruvate provides cardioprotection in the experimental model of myocardial ischemic reperfusion injury. Life. Sci. 2006, 79(1): 38-44
  • Arya D.S., et al. Myocardial salvaging effects of Ocimum sanctum in experimental model of myocardial necrosis: a haemodynamic, biochemical and histoarchitectural assessment. Current Science. 2006, 91(5): 667-672
  • Bansal, P., et al. Cardioprotective effect of lycopene in the experimental model of myocardial ischemia-reperfusion injury. Mol. Cell. Biochem. 2006, 289(1-2): 1-9
  • Saad, S.Y. et al. Cardiotoxic effects of arsenic trioxide/imatinib mesilate combination in rats. J. Pharm. Pharmacol. 2006, 58(4): 567-573
  • Saad, S.Y. et al. Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats. Basic Clin. Pharmacol. Toxicol. 2006, 99(6): 412-417
  • Singh, A.D. et al. Cardioprotective effects of bosentan, a mixed endothelin type A and B receptor antagonist, during myocardial ischaemia and reperfusion in rats. Basic Clin. Pharmacol. Toxicol. 2006, 98(6): 604-610
  • Zhang, Y-M. et al. Effects of N-n- butyl haloperidol iodide on myocardial ischemia/reperfusion injury and Egr-1 expression in rat.Acta Biochim. Biophys. Sin. 2006, 38(6): 435-441
  • Fard, M.H., et al. Cardioprotective activity of fruit of Lagenaria siceraria (molina) Standley on doxorubicin induced cardiotoxicity in rats. Int. J.Pharmacol. 2008, 4(6): 466-471
  • Akpanabiatu, M.I., et al. Effects of interaction of vitamin A and Rauwolfia vomitoria root bark extract on marker enzymes of cardiac diseases. Indian Journal of Clinical Biochemistry. 2009, 24(3): 241-244
  • Arya, D.S., et al. Effect of Piper betle on cardiac function, marker enzymes and oxidative stress in isoprotenerol-induced cardiotoxicity in rats. Toxicol. Mech. Methods. 2010, 20(9): 564-571
  • Başbuğan, Y., et al. An investigation on serum troponin concentration in healthy ruminants. Kafkas Univ Vet Fak Derg 2010,16(4): 641-645
  • Suanarunsawat, T. et al. Antioxidant activity and lipid-lowering effect of essential oils extracted from Ocimum sanctum L. leaves in rats fed with high cholesterol diet. J. Clin. Biochem. Nutr. 2010, 46(1): 52-59

Clinical Chemistry Panel

For more information or to view more reagents within the clinical chemistry panel, please click here

Cardiology Panel

For more information or to view more reagents within the cardiology panel, please click here

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