Genomic Laboratory Technologies

Relatively new to the Randox Group is our Randox Genomics Services department, having been hugely successful in aiding the COVID testing programme, our established sequencing laboratory has been specifically designed and set up to fulfil a unique range of testing from our specialised laboratory in Northern Ireland.

Nucleic Acid Extraction and Isolation

Thermo Scientific KingFisher Flex

Automated nucleic acid extraction instruction that provides high throughput purification of up to 96 samples per run within 40 minutes.

Sample Quality Control

ThermoFisher Scientific Qubit 3.0 & Qubit Flex 

 

Capable of fast and specific nucleic acid quantification using fluorescence-based dye application, suitable for a lower throughput. More sensitive and accurate protocol than UV absorbance.

ThermoFisher Scientific Varioskan LUX 

 

Capable of rapid fluorescence-based UV absorbance nucleic acid analysis, suitable for high throughput of processing samples.

Agilent 4200 TapeStation System

 

An automated electrophoresis solution that with a scalable throughput (1-96 samples) can provide results in 1-2 minutes per plate with excellent reproducibility for sizing, concentration and integrity assessment.

Liquid Handling

Tecans 

 

Freedom EVO 150 base unit tecans, are automated liquid handling machines, enabling fully traceable, scalable (1-96 samples) automated library preparation including QC and library pooling.

Integra Viaflo 384

 

Viaflo 384 enables transfers of 24, 96 and 384 samples in a single step, thus increasing pipetting throughput and reproducibility significantly.

Integra Assist Plus

 

Pipette adapter: accommodates all Integra electronic multichannel pipettes- with fixed and adjustable tip spacing and the D-One single channel pipetting module.

Sequencing

Applied Biosystems SeqStudio Genetic Analyser 

 

Low-throughput benchtop system that delivers gold-standard Sanger sequencing technology and fragment analysis, easily used across a broad range of applications.

Next Generation Sequencing

MiSeq 

 

The MiSeq System is capable of automated paired-end reads and up to 15 Gb per run, delivering over 600 bases of sequence data per read.

NextSeq 2000

 

NextSeq 2000 System supports emerging and mid-throughput sequencing applications as well as a broad range of methods such as exome sequencing, target enrichment, single-cell profiling, transcriptome sequencing, and more. It offers an intuitive workflow with load-and-go ease and visual cues about run status. The NextSeq 2000 allows whole-exome sequencing of up to 48 samples in 33 hours.

NovaSeq6000

 

The most powerful sequencing instrument Illumina produce with the ability to provide scalable throughput for efficient whole-genome, whole exome and whole-transcriptome sequencing through sequencing by synthesis and patterned flow cell technology.

Genotyping

Illumina iScan

 

An innovative array scanner that supports rapid, sensitive, and accurate imaging of Illumina BeadChips for exceptional genetic analysis results. The iScan System can scan thousands of array samples per day, without sacrificing data quality or reproducibility. It supports an expansive portfolio of genetic analysis assays, from high-throughput genotyping to DNA methylation analysis.

Useful Resources

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