Human Whole Genome Sequencing (hWGS) involves sequencing very single base in your DNA (approximately 3.2 billion) to identify any variants that may increase the risk of developing certain conditions or impact health/lifestyle. This sequencing method has many applications including identifying genetic disorders, mutations responsible for cancer progression, as well as monitoring disease outbreaks.

 

Advantages

• High-resolution view of the genome
• Detection of all variant types
• Low cost, fast library preparation

16s rRNA gene sequencing involves the analysis of the prokaryotic 16s ribosomal RNA gene which is found in all bacteria and archaea. This sequencing approach is extremely useful for microbiome research studies. 16s rRNA gene sequencing has a number of applications including, environmental, clinical and food

 

Advantages  

• Identification and taxonomic classification of bacterial species
• Fast speed and cost efficient
• Discovery of novel pathogens

 

Shotgun sequencing reads all the genomic DNA in the sample, rather than just one specific region. This sequencing method provides a vast amount of genetic information as it can identify archaea, bacteria, fungi and viruses.

Advantages

• Less labour intensive than other sequencing methods.
• Faster process than clone-clone sequencing
• Requires less DNA