Key Benefits of the Randox CRP reagent
The Randox CRP reagent receives limited interferences from Conjugate and Free Bilirubin, Haemoglobin, Intralipid and Triglycerides.
Wide measuring range
The Randox CRP assay can comfortably detect levels outside of the healthy range measuring between 2.88 – 220 mg/l.
Stable until expiry date when stored at +2 to +8⁰C
Other features of the Randox CRP reagent
- Immunoturbidimetric method
- Liquid ready-to-use reagents
- Stable until expiry date when stored at +2 to +8⁰C
- Measuring range 2.88 – 220 mg/l
|CP7950||R1 7 x 20ml |
R2 2 x 12ml
|CP9742||R1 6 x 66ml |
R2 6 x 13ml
|Hitachi 917/Mod P|
Beckman Coulter AU Series
|CP3826||R1 6 x 20ml |
R2 3 x 9ml (Latex Enhanced)
|CP2714||100T||Glass Latex Slide Test||-||-|
|CP1423||100T||Disposable Latex Slide Test||-||-|
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is the CRP assay used for?
What is CRP?
C – reactive protein (CRP) is an acute phase protein found in blood plasma and produced by the liver. The concentration levels of CRP increase in response to cytokines which are produced by white blood cells during inflammation, infection and tissue injury.
What is the CRP assay used for?
Increased C-reactive protein concentrations occur much earlier compared to other acute phase reactants. It can be detected in the bloodstream within 4 to 6 hours. For more information on acute phase reactants, please click here [external link]. However, with tissue damage, the concentration levels of C-reactive protein in the blood can double every 6 hours. This rapid response to trauma or infection is the distinguishing feature of CRP. In addition, CRP levels return to normal quickly at the end of an acute episode making CRP useful for both the detection of acute episodes and the monitoring of treatment.
A complete clinical history is required for the accurate interpretation of CRP levels. CRP levels within the normal range may be affected by a number of different factors and should always be compared to previous values.
The Randox CRP assay is used for the quantitative in vitro determination of CRP concentrations in serum. The Randox CRP assay can be used to aid in the detection of:
- Viral infections
- Bacterial infections, including those in neonates
- Infectious diseases
- Tissue injury
- Inflammatory conditions
- Myocardial infarction
- Monitoring recovery from surgery, particularly renal transplant patients
- Valtchanova-Matchouganska, A., et al. The role of C-reactive protein in ischemia/reperfusion injury and preconditioning in a rat model of myocardial infarction. Life Sci. 2004, 75(8): 901-910
- Esmaillzadeh, A., et al. Fruit and vegetables intakes, C-reactive protein, and the metabolic syndrome. Am. J. Clin. Nutr. 2006, 84: 1489-1497
- Dupuy, A.M., et al. Evaluation of the high-sensitivity, full-range Olympus CRP OSR6199 application on the Olympus AU640R. Clin. Chem. Lab. Med. 2007, 45(3): 402-406
- Dupuy, A.M., et al. Adaptation and evaluation of the Randox full-range CRP assay on the Olympus AU2700R. J. Clin. Lab. Anal. 2007, 21: 34-39
- Ramírez Velázquez, C., et al. High-affinity C-reactive protein as inflammatory marker. Rev. Alerg. Mex. 2007, 54(1): 7-13
- Škopková, M., et al. Protein array reveals differentially expressed proteins in subcutaneous adipose tissue in obesity. Obesity. 2007, 15(10): 2396-2406
- Fabre, S., et al. Protein biochip array technology for cytokine profiling predicts etanercept responsiveness in rheumatoid arthritis. Clin. Exp. Immunol. 2008. 153(2): 188-195
- Kjelgaard-Hansen, M., et al. Canine serum C-reactive protein detected by means of a near-patient test for human C-reactive protein. J. Small Anim. Pract. 2008, 49(6): 282-286
- Bargnoux, A.C., et al. Evolution of coronary artery calcifications following kidney transplantation: relationship with osteoprotegerin levels. Am. J. Transplant. 2009, 9(11): 2571-2579
- Connolly, G.M., et al. Elevated serum phosphate predicts mortality in renal transplant recipients. Transplantation. 2009, 87(7): 1040-1044. (CRP)
- Klenner, S., et al. Evaluation of three automated human immunoturbidimetric assays for the detection of C-reactive protein in dogs. J. Vet. Diagn. Invest. 2010, 22: 544-552
- Martins, R.A. et al. Glycated haemoglobin and associated risk factors in older adults. Cardiovasc. Diabetol. 2012, 11: 13
- Hokayem, M., et al. Grape polyphenols prevent fructose-induced oxidative stress and insulin resistance in first-degree relatives of type 2 diabetic patients. Diabetes Care. 2013, 36(6): 1454-1461