Key benefits of the Randox sdLDL-C reagent
Exceptional correlation with the gold standard method
The Randox methodology was compared against the gold standard method, ultracentrifugation, and the Randox sdLDL-C reagent showed a correlation coefficient of r=0.99
Randox sdLDL-C utilizes the “Denka Seiken” method
The “Denka Seiken” method produces results in as little as ten minutes, facilitating faster patient diagnosis and treatment plan implementation. Previously, ultracentrifugation and electrophoresis based methods were options for the measurement of sdLDL cholesterol, which are both laborious and time consuming
Wide measuring range
The healthy upper limit for sdLDL-C is 4.90mmol/l. The Randox sdLDL-C assay can comfortably detect levels outside of the healthy range, measuring between 4 – 100 mg/dl
Other features of the Randox sdLDL-C reagent
- Denka Seiken method
- Liquid ready-to-use reagents
- Correlation coefficient of r=0.99 with Ultracentrifugation method
- Stable to expiry when stored at +2 to +8°C
- Measuring range 4 – 100 mg/dl
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is the sdLDL-C assay used for?
Clinical Significance of sdLDL-C
There are two main types of LDL cholesterol which vary in size through genetic determination and dietary lipid intake, ranging from small and dense to large and buoyant LDL. All LDL cholesterol transports triglycerides and cholesterol to bodily tissues, however, their atherogenesis varies according to their size. Smaller particles like sdLDL-C can more readily permeate the arterial wall and are more susceptible to oxidation.
sdLDL-C in clinical practice
Extend your lipid profile
sdLDL measurement is an extremely valuable lipid as it is a vital risk marker for the detection of myocardial infarction. Research indicates that individuals with a predominance of sdLDL-C have a three-fold increased risk of myocardial infarction. Elevated levels of sdLDL-C are caused by a diet high in saturated fat’ a sedentary lifestyle, insulin resistance, prediabetes and genetic deposition. Measurement of sdLDL-C enables the clinician to gain a comprehensive overview of lipid risk factors and to tailor treatment accordingly. For more information on the low-density lipoprotein subclass patterns and myocardial infarction, click here [external link].
Check out the Randox sdLDL-C Whitepaper
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