Alanine Aminotransferase (ALT) Reagent

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ALT

Key Benefits of the Randox Alanine Aminotransferase (ALT) reagent

Wide measuring range

The healthy range for ALT is 7 – 56 U/l but the Randox Alanine Aminotransferase (ALT) assay can comfortably detect levels outside of the healthy range, measuring from 4.25 – 666 U/l

Excellent Stability

ALT is stable to expiry when stored at +2 to +8°C

Suitable for use on a range of analysers

The Randox Alanine Aminotransferase (ALT) Reagent is suitable to use on a number of third party analysers Including Abbott, Olympus, Cobas and Hitachi. To enquire about an Instrument Specific Application (ISA), please click the contact us button below.

Other Features of the Alanine Aminotrabsferase (ALT) reagent

  • IFCC method
  • Available as liquid and lyophilised reagents
  • Stable to expiry when stored at +2 to +8°C
  • Wide Measuring range 4.25 – 666 U/l
Cat NoSizeAnalyserEasy Read
Easy Fit
 
(L) Indicates liquid option
AL120020 x 2mlGeneral Use--
AL120510 x 10mlGeneral Use--
AL12685 x 20mlGeneral Use--
AL23605 x 100mlGeneral Use--
AL38756 x 21ml (L)RX Daytona/Imola
Hitachi 717/911/912/704/902


AL7904R1 7 x 50ml (L)
R2 3 x 60ml
Hitachi 717/911/912/704/902
RX Daytona/Imola


AL7930R1 7 x 100ml (L)
R2 3 x 60ml
Hitachi 717/911/912/704/902
RX Daytona/Imola


AL3801R1 6 x 51ml (L)
R2 6 x 14ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


AL8006R1 6 x 56ml (L)
R2 6 x 20ml (Mod IFCC)
RX Suzuka
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








AL8304R1 4 x 20ml (L)
R2 4 x 7ml (Mod IFCC)
RX Daytona +/Monaco
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

Randox ALT-Colorimetric

Cat NoSizeAnalyserEasy Read
Easy Fit
 
(S) Indicates standard included in kit
AL1002 x 100mlGeneral Use--
AL1462 x 100ml (S)General Use--

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is ALT assay used for?

What is ALT?

Alanine Aminotransferase is one of the enzymes within the aminotransferases group and are among the most sensitive liver enzymes. The highest concentrations of the ALT enzyme can be in the liver, with decreasing concentrations found in the kidneys, heart, skeletal muscle, pancreas, spleen and lung tissue respectively.

What is the ALT assay used for?

ALT measurements are used in the diagnosis of hepatic damage and diseases including viral hepatitis and cirrhosis.

The normal concentration levels of ALT in the blood are low, however, when damaged, the liver releases more ALT into the blood causing the concentration levels to rise.  When diagnosing for hepatic damage, the root cause of the damage can be established, such as disease, drug, or injury

The ALT test not only allows for the diagnosis of liver disease but also allows for the diagnosis of the root cause of the disease

It is often tested in combination with the aspartate aminotransferase (AST) test as part of the hepatic panel with alanine aminotransferase levels being higher in most types of liver disease.  For more information on the validity and clinical utility of AST and ALT when assessing disease severity, please click here [external link].

  • Mula-Abed, W-A. S. and Hanna, B.E. Measurement of serum fructosamine as an index of glycated protein in patients with nephrotic syndrome and chronic liver diseases. Bahrain Medical Bulletin 2001, 23(4)
  • Busek, S.U., et al. Hepatitis C and Hepatitis B Virus Infection in Different Hemodyalisis Units in Belo Horizonte, Minas Gerais, Brazil. Mem. Inst. Oswaldo Cruz, 2002, 97(6): 775-778
  • Oyejide, O.O. and Olushola, L. Hepatoprotective and antioxidant properties of extract of Carmellia sinensis (black tea) in rats. African Journal of Biotechnology 2005, 4(11): 1432-1438.
  • Saad, S.Y. et al. Cardiotoxic effects of arsenic trioxide/imatinib mesilate combination in rats. J. Pharm. Pharmacol. 2006, 58(4): 567-573
  • Noori, S., et al. Biochemical effectiveness of cocoa powder on electrolytes homeostasis, liver and cardiac specific enzymes and renal function. Pakistan Journal of Nutrition 2009, 8(6): 882-886
  • Suanarunsawat, T. et al. Antioxidant activity and lipid-lowering effect of essential oils extracted from Ocimum sanctum L. leaves in rats fed with high cholesterol diet. J. Clin. Biochem. Nutr. 2010, 46(1): 52-59
  • Awe, S. and Olayinka E.T. Effect of cashew wine on histology and enzyme activities of rat liver. J. Toxicol. Environ. Health Sci. 2011, 3(2): 31-38
  • Iribhogbe, O.I., et al. Effects of vitamins A, C and E on liver function in pregnancy. Asian Journal of Medical Sciences. 2011, 3(1): 8-13
  • El-Abhar, H.S. and Schaalan, M.F. Topiramate-induced modulation of hepatic molecular mechanisms: an aspect for its anti-insulin resistant effect. PLoSONE. 2012, 7(5): e37757

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