CK-MB

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Key Benefits

Liquid and lyophilised reagents available

Offering convenience and choice

Wide measuring range

The Randox CK-MB assay has a wide measuring range of 16.2 – 2216 U/l which will comfortably detect levels outside of the healthy limits

Excellent stability

Stable to expiry when stored at 2-8°C

Other Features

  • Liquid and lyophilised reagents available
  • Stable to expiry when stored at 2-8°C
  • Measuring range 16.2 – 2216 U/l
Cat NoSizeAnalyserEasy Read
Easy Fit
 
(L) Indicates liquid option
CK129619 x 2.5mlGeneral Use--
CK15535 x 20mlGeneral Use--
CK3813R1 4 x 20ml
R2 4 x 6ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


CK4043R1 4 x 20ml (L)
R2 4 x 6ml
RX Daytona/Imola
Hitachi 717/911/912/704/902


CK7946R1 6 x 20ml
R2 3 x 10ml
Hitachi 717/911/912/704/902
RX Daytona/Imola


CK8026R1 4 x 20ml
R2 4 x 6ml
RX Suzuka
Abbott Architect
Hitachi 917/Mod P
Konelab 20i/30i/60i
Beckman Coulter AU Series








CK9717R1 6 x 21ml
R2 2 x 15ml
Hitachi 917/Mod P
Abbott Architect
Konelab 20i/30i/60i
Beckman Coulter AU Series






Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

What is CK-MB assay used for?

Creatine Kinase (CK) is internationally accepted as a sensitive and specific indicator of acute myocardial infarction (AMI). There are 3 iso-enzymes of CK, CK-MM, CK-MB and CK-BB. CK-BB is produced by the brain in very small insignificant amounts. CK-MM is produced by the skeletal and heart tissue and CK-MB is produced by the heart muscle. In the vast majority of cases the CK activity rises within 6 hours of an acute infarction. After about 20 hours maximum values are observed. The CK activity generally returns to normal between the fourth and fifth day post- infarction.

  • Pal, S. Estimation of CKMB from RIQAS control serum at 37 degree celsius. Indian Journal of Clinical Biochemistry, 2002, 17(2): 88-90
  • Huang, Z-Q., et al. Effects of N-n-butyl haloperidol iodide on rat myocardial ischemia and reperfusion injury and L-type calcium current. Acta Pharmacol. Sin 2003, 24(8): 757-763
  • Mohiti, J., et al. The significance of troponin T and CK-MB release in coronary artery bypass surgery. Indian J. Clin. Biochem.2004, 19(1): 113-117
  • Saad, S.Y., et al. Cardiotoxicity of doxorubicin/paclitaxel combination in rats: effect of sequence and timing of administration. J. Biochem. Mol. Toxicol. 2004, 18(2): 78-86
  • Arya D.S., et al. Pyruvate provides cardioprotection in the experimental model of myocardial ischemic reperfusion injury. Life. Sci. 2006, 79(1): 38-44
  • Arya D.S., et al. Myocardial salvaging effects of Ocimum sanctum in experimental model of myocardial necrosis: a haemodynamic, biochemical and histoarchitectural assessment. Current Science. 2006, 91(5): 667-672
  • Bansal, P., et al. Cardioprotective effect of lycopene in the experimental model of myocardial ischemia-reperfusion injury. Mol. Cell. Biochem. 2006, 289(1-2): 1-9
  • Saad, S.Y. et al. Cardiotoxic effects of arsenic trioxide/imatinib mesilate combination in rats. J. Pharm. Pharmacol. 2006, 58(4): 567-573
  • Saad, S.Y. et al. Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats. Basic Clin. Pharmacol. Toxicol. 2006, 99(6): 412-417
  • Singh, A.D. et al. Cardioprotective effects of bosentan, a mixed endothelin type A and B receptor antagonist, during myocardial ischaemia and reperfusion in rats. Basic Clin. Pharmacol. Toxicol. 2006, 98(6): 604-610
  • Zhang, Y-M. et al. Effects of N-n- butyl haloperidol iodide on myocardial ischemia/reperfusion injury and Egr-1 expression in rat.Acta Biochim. Biophys. Sin. 2006, 38(6): 435-441
  • Fard, M.H., et al. Cardioprotective activity of fruit of Lagenaria siceraria (molina) Standley on doxorubicin induced cardiotoxicity in rats. Int. J.Pharmacol. 2008, 4(6): 466-471
  • Akpanabiatu, M.I., et al. Effects of interaction of vitamin A and Rauwolfia vomitoria root bark extract on marker enzymes of cardiac diseases. Indian Journal of Clinical Biochemistry. 2009, 24(3): 241-244
  • Arya, D.S., et al. Effect of Piper betle on cardiac function, marker enzymes and oxidative stress in isoprotenerol-induced cardiotoxicity in rats. Toxicol. Mech. Methods. 2010, 20(9): 564-571
  • Başbuğan, Y., et al. An investigation on serum troponin concentration in healthy ruminants. Kafkas Univ Vet Fak Derg 2010,16(4): 641-645
  • Suanarunsawat, T. et al. Antioxidant activity and lipid-lowering effect of essential oils extracted from Ocimum sanctum L. leaves in rats fed with high cholesterol diet. J. Clin. Biochem. Nutr. 2010, 46(1): 52-59
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