Wide measuring range
With a measuring range of 0.56-20.9 mg/l in serum and 0.04-3 mg/l in urine, it will comfortably detect levels outside of the healthy range of 0.9-3.0 mg/l (in serum)
Stable to expiry when stored at 2-8⁰C
The method is linear up to 0.56 mg/l
- Liquid ready-to-use reagents
- Stable to expiry when stored at 2-8⁰C
- Measuring range 0.56-20.9 mg/l
|BM3887||R1 2 x 11ml |
R2 2 x 4.3ml
|BM8016||R1 2 x 11.6ml |
R2 2 x 4.9ml
Hitachi 917/Mod P
Beckman Coulter AU Series
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Beta-2 Microglobulin assay used for?
Beta-2-Microglobulin is a low molecular weight protein found on the surface of most cells, including white blood cells. When kidney disease is suspected, comparing blood and urine levels helps identify where the kidney is damaged.
In healthy individuals, is synthesized at a rate of 9 mg/hours and is eliminated mostly by the kidneys. Therefore the assay is useful to find out the following:
- Beta-2 Microglobulin is normally filtered out of the blood by the kidney’s tubules. In glomerular kidney disease, the glomeruli can’t filter it out of the blood, so levels increase in blood and decrease in urine
- In tubular kidney disease, the tubules can’t reabsorb it back into the blood, so urine levels rise and blood levels fall
- High levels of Beta-2 Microglobulin in urine may help detect the early stages of kidney damage
- In AIDS serum, Beta-2 Microglobulin is an accurate predictor of the progression of the disease in HIV infected groups including haemophiliacs. Levels above 5 mg/l indicate rapid progression and poor prognosis
- In various mylomas, Beta-2 Microglobulin levels have been related to tumour mass, prognosis, disease activity and effectiveness of treatment. Levels below 4 mg/l indicate better prognosis than levels above 20 mg/l