Banned substance furazolidone (AOZ) detected in shrimp at French border

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Banned substance furazolidone (AOZ) detected in shrimp at French border

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14 April 2021: Banned substance furazolidone (AOZ) detected in shrimp at French border

As per an alert through RASFF – the Rapid Alert System for Food and Feed for the EU, shrimp imported from India has been rejected at the French border in March 2021 for containing a banned substance, known as furazolidone (AOZ). The shrimp product has since been destroyed and did not make it into the market for distribution.

Nitrofuran antibiotics, the parent compound of AOZ, were banned for use in animal food production in the EU in 1995 and 2009 in the US for its reported carcinogenic and mutagenic characteristics. However due to the drugs low cost and effectiveness in controlling disease it is still in use despite the ban.

Randox Food Diagnostics

Randox Food Diagnostics have developed a highly accurate and reliable immunoassay array which detects Nitrofuran residues including AOZ, AMOZ, AHD and SEM.

Available on the Evidence Investigator, our Antimicrobial Array III utilises our patented Biochip Array Technology which provides screening of up to 54 meat and seafood samples. The Evidence Investigator provides results for multiple drug residues and toxins in just 2.5 hours, saving the user both time and money compared to other screening and confirmatory methods.

Randox Food Diagnostics also provide a vast variety of ELISA kits to test for antibiotics in meat and seafood tissue, offering excellent cross-reactivity and unrivalled limits of detection. With results providing great correlation with confirmatory methods, we ensure that better science means safer food.

Want to know more?

For more information on tissue screening methods from Randox Food Diagnostics please visit the links below.

www.randoxfood.com/meat-and-seafood-analysis/

Alternatively contact us via email: info@randoxfooddiagnostics.com

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Record level of alcohol deaths recorded during COVID-19 pandemic

Record level of alcohol deaths recorded during COVID-19 pandemic

22 March 2021

Deaths caused by alcohol consumption hit a new high during the first nine months of 2020, new figures for England and Wales show.

Between January and September, 5,640 deaths were registered with this cause – an increase of 16% on the same period in 2019. This significant increase has been the highest recorded figure since records began in 2001. The high rates spanned the period during and after the first national COVID-19 lockdown, according to new figures from the Office for National Statistics.

As in past years, rates of male alcohol-specific deaths were twice those seen for women. Experts say the coronavirus pandemic will have had little effect on how the data was gathered and recorded. But it is not clear how much it may have contributed to the deaths.

A spokesman for ONS said:

“Today’s data shows that in the first three quarters of 2020, alcohol-specific deaths in England and Wales reached the highest level since the beginning of our data series, with April to September, during and after the first lockdown, seeing higher rates compared to the same period in previous years.”

“The reasons for this are complex and it will take time before the impact the COVID-19 pandemic has had on alcohol-specific deaths is fully understood.”

Effects of Alcohol

Alcohol’s impact on your body starts from the moment of consumption. While an occasional glass of wine or beer isn’t a cause for concern, the cumulative effects of drinking beer, wine or spirits can take its toll.

Excessive consumption can impact various parts of the body. Effects can range from weakening of the immune and digestive system, to inflammation and sugar level issues.

Our ‘Effects Of’ Series provides a range of educational posters that ca be displayed in workplaces. Click here to view them.

Did you know that alcohol misuse at work can:

  • increase sickness and absenteeism
  • harm the reputation of the business
  • decrease productivity
  • put employees and members of the public in unnecessary risk

Breath Testing in the Workplace

Handheld breathalysers are an ideal device for conducting workplace alcohol testing. Quick and easy testing provides an instant readout of the donor’s breath alcohol measurement.  Simply compare the reading to the cutoff defined in your own drug and alcohol testing policy.

Breathalyser devices gauge blood alcohol content (BAC) by measuring deep lung air. This type of testing can accurately determine whether a person has recently consumed alcohol or is currently over the legal or pre-determined limit. Breathalyser calibrations are maintained in accordance with the manufacturers specifications and periodically accuracy checked to ensure results are accurate and reliable.

How Randox Testing Services can help

At Randox Testing Services, we are pleased to offer a range of stand-alone alcohol tests or combinations of tests to meet your needs.

Throughout the COVID-19 pandemic, RTS have continued to provide drug & alcohol testing services. At all times, we have ensured our staff are equipped to provide sensible advice and flexible solutions to drug & alcohol testing.

Whether for use in workplace settings or for use in court proceedings for medico-legal cases, our range of alcohol testing methods will provide you with accurate and reliable results at competitive prices.

For more information on our alcohol testing services, or to request a quote, contact us using any of the below details.

Website: www.randoxtestingservices.com

Email: testingservices@randox.com

Phone: +44 (0) 28 9445 1011

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Why does Randox sponsor Equine Sports events?

Why does Randox sponsor Equine Sports?

16 March 2021: Why does Randox sponsor Equine Sports?

Some may be wondering, why is a healthcare company so invested in the equine industry? Why would they sponsor the world’s most famous steeplechase?

It’s a labour of love… Peter FitzGerald’s fond attachment to the equestrian world, together with almost 40 years’ experience in the in vitro diagnostics industry, was the perfect match.

Clinical diagnostics is at the heart of Randox and our experience and expertise has paved the way for the development of innovative and accurate diagnostic products for Equine Health.

You could say ‘it runs in our blood.’

With 70% of all medical decisions based on the analysis of blood, Randox are set to release the VeraSTAT-V, a stable-side Equine Serum Amyloid A test device designed to detect levels of inflammation in horse blood in a matter of minutes.

The ability to quickly detect and monitor your horse’s health, at the stable side, brings huge benefits to both horse and owner. Early detection of inflammatory states means treatment plans can start sooner, recovery periods are shorter, and the horse can return to work healthy much earlier.

When performance is key, monitoring inflammation is vital.

Whether it’s detecting inflammation related to joint injury, or screening for infection before or after transport, competition or surgery, the VeraSTAT-V is a valuable means to monitor Equine Health.

At Randox, we have enjoyed a long-standing partnership with the Jockey Club and will continue to deliver innovative diagnostics solutions to the Equine Industry for the years ahead.

Keep an eye out for the release of the VeraSTAT-V – coming soon.

For all Equine SAA inquiries, please email marketing@randox.com or visit www.randox.com/veraSTAT for more information.

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The Impact of Coronavirus on Drug Use in Europe

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15 March 2021: Impact of Coronavirus on Drug Use in Europe

The effect of COVID-19 on the consumption of drugs in Europe has been varied depending on the drug type concerned. Overall, 51.6% of participants in a survey have increased their drug or alcohol consumption and 57.3% reported taking drugs more frequently. The main explanations for these inclines are due to boredom and anxiety, likely due to the imposed restrictions of strict lockdown measures.

According to Statista, Cannabis remains to be the most popular drug used within Europe as 27.2% of respondents revealed that they have used the drug in their lifetime compared to only 5.4% using cocaine. Since the COVID-19 pandemic began in March 2020, regular users of Cannabis have increased their usage, however it is important to note that this has only affected 10% of respondents.

There has been a major hold on the party lifestyle with the shut-down of nightclubs and lack of festival events. As well as, a decrease in the supply of readily available drugs on the market resulting from transport restrictions at country borders. This has impacted the usage of recreational drugs such as cocaine, LSD and MDMA which have seen a decline. The Global Drug Survey revealed that 40% of respondents have used these drugs less during the pandemic.

This detrimental trend has resulted in the domestic production of synthetic opioids. There is a very high risk that substitutes such as fentanyl will become more common. This prediction is concerning due to the dangers associated with such drugs leading to addiction and overdoses. For instance, fentanyl compared to heroin is 50 times stronger.

Public Health England has also released a warning relating to the rise in illegally produced prescription drugs sold as benzodiazepines. These cause harmful health issues due to the mix of unsafe and unknown components.

Randox Toxicology

Randox Toxicology are helping to fight drug trafficking by continually investing in new technologies to aid in the rapid and large-scale screening for drugs of abuse. We are world leaders in drug screening solutions with the capability of detecting over 500 drug and drug metabolites using our innovative Biochip Array Technology – the most comprehensive on the drug testing market. Our patented Biochip Array Technology works across a variety of matrices including whole blood, urine, oral fluid, meconium, vitreous humor and hair.

Using our revolutionary Biochip Array Technology, the Evidence MultiSTAT is a fully automated benchtop analyser that enables onsite, simultaneous testing for up to 21 classical, synthetic or prescription drugs from a single sample in under 20 minutes. This quick and highly reliable technology makes it perfect for use in non-laboratory settings for people with no lab experience.

To find out more about our Biochip Array Technology and our Evidence Series range of analysers, visit www.randoxtoxicology.com or email info@randoxtoxicology.com

 

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World Kidney Day 2021

World Kidney Day 2021

11th March 2021 is World Kidney Day, a worthy global campaign aimed at tackling “the hot topic everyone’s ignoring”.

Raising awareness of a disease that ‘one in every nine’ people worldwide suffer from, is something we take seriously.

Here at Randox, our vision is to improve healthcare worldwide and ensure patients across the globe have access to the latest advancements in clinical diagnostics to tackle diseases such as Chronic Kidney Disease.

This year World Kidney Day 2021 focuses on being able to live well with kidney disease. Many of us take for granted being able to live a normal life without the side effects such as fatigue, pain, depression, sleep problems etc. However Kidney disease can be huge challenge patients and those around them. The impacts of kidney disease can take a toll of day to day life and the ability to participate in activities such as work, travel, and socialising.

Kidney diseases are very common and can be harmful, but the good news is they are also very treatable!

Randox offer a comprehensive panel of kidney health tests, working to ensure timely and accurate diagnosis of kidney function problems to combat patient challenges early.

For example, low levels of albumin indicate signs of kidney damage in the early stages when diagnosis is key. Testing for albumin can identify individuals with diabetic nephropathy (damage to the kidneys caused by diabetes) around 10 years earlier than standard protein tests. The Randox albumin test can therefore enable preventative measures to be taken to reduce your risk of developing kidney disease.

With early diagnosis we can improve patient treatment outcomes and reduce the number of people across the world suffering with kidney health problems.

If you are a clinician or lab interested in running renal function assays, download our Reagents Brochure or email reagents@randox.com

If you want to find out the status of your own Kidney Health, book a health check with Randox Health today.

 

 

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Approaching the Fundamental Impact of STIs Worldwide

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02 March 2021

The Global Economic Burden of STIs & The Impact of the COVID-19 Pandemic on Sexual Health Whitepaper Download 

Sexual Health encompasses; genito-urinary medicine, sexually transmitted infections (STIs), HIV, contraception, psychosexual medicine, abortion services, teenage pregnancy and sexual and reproductive health. It is delivered in various settings, providing care across specialised services as well as through primary and third sector organisations.

Sexual and reproductive health is a fundamental public health issue and is clearly recognised by the World Health Organisation (WHO). This whitepaper focuses on the profound impact of sexually transmitted infections (STIs) worldwide with WHO reporting that more than 1 million STIs are acquired every day (WHO, 2020).

The whitepaper discusses issues such as antimicrobial resistance, in particular gonorrhoea, and the challenges faced in a social and public concept due to the COVID-19 pandemic.

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Biotin supplementation interference in health testing

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12 February 2021

Biotin supplementation interference in health testing

How much do you know about Biotin? Commonly known as Vitamin B7, Biotin is taken by as many as 20% of people, including high profile celebrities like Kylie Jenner, Kim Kardashian and Vanessa Hudgens, for its hair and nail-strengthening properties.

If you take biotin supplements, it is important to know the effects it can have on particular blood tests, should you visit your GP or local hospital.

Whilst there are various diagnostic health tests out there, including fertility hormone tests, prostate tests, and tests for troponin – a marker released into the blood during a heart attack – that are known to be affected by elevated levels of biotin, there are other tests available, including those provided by Randox, that are not impacted.

The reason that so many non-Randox tests are impacted by biotin is that biotin is widely used throughout the biotechnology industry in the development of diagnostic tests.

ELISA tests in particular (tests that measure the reaction of antibodies to identify a substance) often make use of antibodies labelled with biotin, to detect toxins or other foreign substances within the body.

In most instances, the biotin will bind to a protein called streptavidin. This bonding is the strongest non-covalent biological interaction known, and is therefore particularly useful in binding antibodies within diagnostic tests.

But with more and more people exceeding the recommended daily dosage for biotin (30 micrograms) by taking up to 10,000 micrograms of biotin in supplements marketed for beauty reasons, many diagnostic tests are being measured inaccurately. Excess biotin in the blood can block the binding of biotin-labelled antibodies to streptavidin within the tests, and the substance being tested won’t be measured accurately.

Laboratory professionals have known about this potential problem for some time. In late November 2017, the FDA (Food and Drug Administration) published a safety notice to make the public and healthcare practitioners more aware that biotin can “significantly interfere with certain lab tests and cause incorrect test results.”

The FDA even reported on one particular case in which a patient died following falsely low troponin (marker of a heart attack) results when the troponin test used was known to have biotin interference. Biotin supplements masked the true diagnosis of a heart attack.

Many patients taking biotin supplements have also been misdiagnosed with a condition called Graves’ disease, an autoimmune condition characterised by an overactive thyroid. In these cases, biotin supplementation led to falsely low levels of thyroid stimulating hormones, and falsely high levels of other thyroid hormones. This particular profile of hormones led to a Graves’ disease diagnosis, in spite of a lack of symptoms, which in Graves’ disease would usually include muscle weakness, a quickened heartbeat, sleeping problems, diarrhoea, weight loss and poor tolerance of heat.

In pregnant women, tests that are impacted by biotin interference may produce falsely low results of beta HCG, more commonly known as the ‘pregnancy hormone’ as it released by the placenta after conception. With low levels of beta HCG, and therefore no confirmation of pregnancy, pregnant women could be exposed to X-rays and CT scans that may harm the developing foetus.

So, what can be done? Suggestions have been made that patients taking biotin supplements should be made to wait before any diagnostic testing is conducted, so that the biotin clears from their system.

But this “Wait and Watch” approach certainly would not work in emergencies. In the case of a heart attack, testing must be conducted as soon as possible to allow for diagnosis, immediate medical intervention and follow-up testing.

At Randox, we are convinced that the risk of analytic interference by biotin supplementation is a serious problem that needs to be more widely recognised and promptly addressed.

In the GP setting, general practitioners must ask their patients if they are taking any biotin supplements and inform the testing laboratory if interference from biotin is a possibility. They should also consider that lab results not matching with a patient’s signs and symptoms may be caused by biotin interference.

In the acute care setting however, it is imperative that biotin technology is not used in diagnostic testing to protect patients from misdiagnosis and subsequently, further health problems.

This is why Randox’s patented Biochip Array Technology does not use biotin technology in its development. This revolutionary methodology, free from Biotin-Streptavidin is not impacted by elevated levels of biotin from supplementation in the same way as Biotin-Streptavidin tests.

So if you have been taking supplements for hair or nail growth, to ease symptoms associated with Multiple Sclerosis, for epilepsy or for a range of other health conditions, and your diagnostic testing has been conducted using Randox Biochip Array Technology, you can rest assured of true, accurate, and reliable results.

Randox Biochip Array Technology is interference-proof.

For further information on the Randox Biochip, visit https://www.randox.com/multiplex-testing/

For any additional questions, please contact Randox PR by email: randoxpr@randox.com or by phoning 028 9442 2413

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Record Seizure of Synthetic Drugs in Spain: A Randox Toxicology Blog

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05 February 2021: Record Seizure of Synthetic Drugs in Spain

In a record seizure of synthetic drugs for Spain, police have confiscated approximately 827,000 ecstasy tablets, 76kg of speed, 39.5kg of crystal meth and 217 litres of liquid amphetamine at the start of 2021.

Eleven people – from Spain, the Netherlands, Romania, Colombia and Italy – were arrested during a joint investigation by the Guardia Civil and national police forces, according to a statement. The police operation, which lasted nearly a year, resulted in the largest synthetic drugs seizure in Spain, and second-largest ecstasy seizure in Europe over the past 20 years.

The criminal organisation was described as “the most important criminal organisation dedicated to the manufacture and trafficking of synthetic drugs in the history of Spanish drug trafficking”.

Once the large haul was in Spain, the drugs were planned to be processed in two laboratories set up in Barcelona.

“It’s worth noting that of all the substances seized, the 217 litres of liquid amphetamine would – had it been processed in the organisation’s Barcelona laboratories – have produced 738kg of speed, making it the biggest ever amphetamine seizure in Spain,” a statement said.

Randox Toxicology

Randox Toxicology are helping to fight drug trafficking by continually investing in new technologies to aid in the rapid and large-scale screening for drugs of abuse. We are world leaders in drug screening solutions with the capability of detecting over 500 drug and drug metabolites using our innovative Biochip Array Technology – the most comprehensive on the drug testing market. Our patented Biochip Array Technology works across a variety of matrices including whole blood, urine, oral fluid, meconium, vitreous humor and hair.

Using our revolutionary Biochip Array Technology, the Evidence MultiSTAT is a fully automated benchtop analyser that enables onsite, simultaneous testing for up to 21 classical, synthetic or prescription drugs from a single sample in under 20 minutes. This quick and highly reliable technology makes it perfect for use in non-laboratory settings for people with no lab experience.

To find out more about our Biochip Array Technology and our Evidence Series range of analysers, visit www.randoxtoxicology.com or email info@randoxtoxicology.com

 

For those who’ve beaten addiction in their own lives Rehab 4 Addiction is a free addiction helpline. Click here.

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Dog Food Recalled Due to Potentially Unsafe Levels of Aflatoxin

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Dog Food Recalled Due to Potentially Unsafe Levels of Aflatoxin

The importance of screening food for toxins has been highlighted this month with the recent news that Midwestern Pet Foods Inc. have extended their product recall after reports that the pet food has potentially caused the deaths of 70 dogs due to containing possibly unsafe levels of aflatoxin.

The Food and Drug Administration said in a statement that it has been “aware of more than 70 dogs that have died and more than 80 that are sick after eating Sportmix pet food.”

Aflatoxins are mycotoxins produced by two species of Aspergillus, a fungus which is especially found in areas with hot and humid climates. Aflatoxins have a wide occurrence in feed and cereals, such as wheat, barley, rice and corn, which are used as ingredients in pet food. At high levels, aflatoxin can cause illness and death in animals.

Midwestern Pet Foods first announced a voluntary recall on Dec. 30, extending it last week. “There have been reports of illnesses and deaths in dogs associated with certain lots of products. No human illnesses have been reported,” the company said in a recall announcement. “Out of an abundance of caution, we have expanded this recall to cover all corn products containing pet foods with expiration dates prior to 07/09/22.”

Aflatoxin poisoning can display in animals with symptoms such as sluggishness, loss of appetite, vomiting, jaundice and diarrhoea.

The expanded recall includes “additional corn-containing lot codes of Sportmix, Pro Pac Originals, Splash, Sportstrail, and Nunn Better dry dog and cat foods” that were produced in its Oklahoma manufacturing plant. A full list of recalled products can be found here.

Randox Food Diagnostics

Randox provide solutions to the agricultural industry by having developed a range of screening platforms for toxins and drug residues within feed and cereals. Multiple mycotoxins can affect crops and drug residues can pass through to feed causing adverse health effects in both humans and animals.

Myco 9 facilitates the detection of up to 9 common mycotoxins from a single sample of cereal or cereal based feed, including aflatoxin B1/B2, aflatoxin G1/G2, deoxynivalenol, diacetoxyscirpenol, fumonisins, ochratoxin A, paxilline, T2 toxin & zearalenone.

For more information on the antibiotic screening arrays available contact us at: info@randoxfooddiagnostics.com

 

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India Must Stop Misusing Antibiotics in Dairy Sector, According to CSE Report

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India Must Stop Misusing Antibiotics in Dairy Sector, According to CSE Report

The Centre for Science and Environment (CSE) has raised concerns over whether the milk we consume is safe. Hosting a virtual meeting in July, the CSE discussed the use of antibiotics with the world’s largest producer of milk, India. Over 188 million tonnes of milk was produced by India over the period of 2018-2019 and lead with 22% of global milk production.

A recent assessment by the CSE has found indication of antibiotic abuse in milk producing cattle.

“We have found that antibiotics are extensively misused in the dairy sector; antibiotic residues remain largely untested in milk, an integral part of Indian diets, particularly of children,” said CSE Director General Sunita Narain. “While we continue to struggle against COVID-19, we are staring at another pandemic like situation – that of antibiotic resistance fueled by the way we are producing our food, which has become chemical-intensive.”

Antibiotics such as penicillin, aminoglycosides and fluroquinolones are being ‘indiscriminately’ used by dairy farmers according to the CSE. These antibiotics are among the most important in human health. The World Health Organisation (WHO) has warned as we face growing concerns over an antibiotic resistance, such antibiotics should be preserved.

Despite laws stating that antibiotics should only be prescribed and administered by a registered veterinarian, the CSE said that some farmers are illegally attaining and injecting animals themselves without the supervision of veterinarians.

“Farmers often sell milk while the animal is under treatment, which increases the chances of antibiotic residues in the milk,” explained Amit Khurana, the CSE’s Food Safety and Toxins Programme Director. “While milk sold directly to consumers is not tested, contrary to what one would expect, processed milk sold in packets is also largely unchecked for antibiotic residues.

“This explains why, despite pooling and processing, packed milk samples from several states had antibiotic residues in the FSSAI’s [Food Safety and Standards Authority of India] milk quality survey of 2018.”

However, CSE noted the virtual meeting has encouraged positive signs of action in the diary industry in India.

“The issues highlighted by the CSE assessment have been well recognised by the experts and stakeholders. These experts have also recommended several measures for minimising antibiotic misuse in the Indian dairy sector.”

In order to minimise the threat of antibiotic resistance, the CSE have recommended “preventative measures” such as;

  • Routine observation of drugs residues in milk
  • Modifying the existing standards for antibiotic residues in milk
  • Limiting misuse of essential antibiotics such as penicillin

Such measures, Khurana noted, are showing some success. “Information shared by various organisations, agencies and experts suggest that ethno-veterinary medicines, better management of sub-clinical mastitis, and good farm management are contributing towards reducing antibiotic misuse.”

“India is now talking about antibiotic resistance in the one-health perspective,” noted Narain. “There is a shared concern, and all voices are now together in expressing that concern.” As such he believes further (and necessary) action will be taken.

“We must ramp up surveillance and testing, put a complete stop to the use of critically important antibiotics and penalise their use,” he added, “and work with farmers and the agriculture-dairy sectors to innovate on solutions.”

Randox Food Diagnostics

Randox Food Diagnostics recognise the pressure the dairy industry is under to mass produce high quality products whilst complying with regulations and have developed the solution. A comprehensive range of easy to use, accurate milk analysis methods for the qualitative and quantitative detection of contaminants in milk.

With 6 Biochip arrays available including the revolutionary InfiniPlex for Milk, Randox Food provide the highest quality testing platforms for the screening of antimicrobials and are the only commercial supplier of a multiplexing anthelmintics array in milk.

Biochip Array Technology saves time and money whilst enabling users to get a deeper insight into milk quality and ensure a safe supply chain.

Contact us at info@randoxfooddiagnostics.com, or visit https://www.randoxfood.com/milk-analysis/ to find out more about our milk testing solutions.

 

 

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