PCR rapid tests for Candida auris for Vivalytic by Bosch now available

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PCR rapid tests for Candida auris for Vivalytic by Bosch now available

 

World’s first fully automated PCR test for detection of the multidrug-resistant fungus at the point of care. 

  • Vivalytic test detects Candida auris in under an hour at the point of care, making it the world’s first test suitable for screenings.
  • Candida auris infection rates are on the rise in Germany and can cause severe infections, for example in the bloodstream (sepsis).
  • Hospitals can use the new screening test to detect colonization, allowing them to implement measures to contain outbreaks.
Bosch Healthcare solutions has developed a PCR test for detecting Candida auris (C. auris) and on the Vivalytic platform. The test is a global innovation now available for order from distribution partners including Randox Laboratories Ltd. and R-Biopharm. This test enables the fully automated detection of the frequently multi-resistant fungus in less than an hour at the point of care. The rapid testing capability also makes it suitable for carrying out screenings when necessary. In contrast, traditional culture tests in centralized laboratories require one to three days, delaying diagnosis and the initiation of targeted treatment. “Considering the heightened risk of severe progression in individuals with pre-existing conditions, we have developed a new test that enables clinics to respond more swiftly,” states Marc Meier, managing director of Bosch Healthcare Solutions. Patients with compromised immune systems, such as those in intensive care, individuals with serious underlying conditions such as diabetes, or those who are immunosuppressed due to cancer or HIV, as well as patients about to undergo invasive surgery, face a heightened risk of active infection with C. auris. The mortality rate for C. auris infections ranges from 30 to 72 percent.
Candida auris  can be transmitted from person to person through contact and contaminated surfaces. When this fungus presents, rapid detection is therefore rapid detection is therefore paramount to enable implementation of effective control and prevention strategies,” says Dr. med. Alexander Maximillian Aldejohann,  deputy head of the Würzburg Laboratory at the National Reference Center for Invasive Fungal Infections (NRZMyk.) Since July 2023, Germany has implemented a limited statutory reporting requirement under the Infection Protection Act. Aldejohann is in favor of extending this reporting obligation: “The fungus has the capacity to rapidly develop resistance to many common antifungal agents coupled with the ability to survive for a relatively long time on surfaces. This high so-called tenacity also increases the risk of outbreaks that are difficult to contain.”

Increasing spread of Candida auris

C. auris is spreading globally. In some states in the U.S, the annual incidence rate has been shown to increase by a factor of 2 to 3. The Robert Koch Institute (RKI) also drew attention to a rise in cases within Germany during the past year in the Epidemiological Bulletin at the at the beginning of May. The RKI points out that in specific areas screening could be beneficial. In the U.S, the annual case count has in the meantime reached the thousands. The Centres for Disease Control and Prevention (CDC) already consider the screening of patients, visitors, and staff for C. auris as a crucial strategy to curb its spread in healthcare settings. While the fungus is harmless for healthy individuals, it can it can lead to severe nosocomial infections, i.e. infections acquired in hospitals or other healthcare environments, in patients at high risk and, if the fungus enters the bloodstream, can trigger sepsis.
Easy handling, rapid detection The Vivalytic Analyser enables effortless testing directly at the point of care: The sample is placed into the test cartridge, which already contains all necessary reagents. The cartridge is then inserted into the Vivalytic Analyser for automated processing. Healthcare professionals require only minimal training to use the system, and the fully automated process significantly lowers the risk of infection. The Vivalytic Analyser thus facilitates rapid and precise diagnostics in PCR quality, bypassing the frequently lengthy process through a central laboratory. Bosch Healthcare Solutions is expecting CE certification for the Vivalytic C. auris test soon.

 

For More Information Please Contact:
Martin Conway, Phone: +44 (0) 28 9442 2413
E-mail: martin.conway@randox.co

 

 


Vivalytic | Strep A

Vivalytic | Strep A

 

Detection of Streptococcus pyogenes

*Currently under development. Not available for sale.

Qualitative RT-PCR detection of Streptococcus pyogenes

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    Quick turnaround time of less than 30 minutes, beneficial for both the patient and for the containment of Strep A reducing aerogenic transmission.

     

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    Convenient 4 step process from sample entry to results. Suitable for use in laboratory and non-laboratory settings.

     

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    Real-time PCR enables rapid and targeted detection up to 4 weeks after the onset of symptoms Streptococcus pyogenes.

Clinical Significance

Group A Streptococcus (GAS) is the primary culprit behind bacterial pharyngitis in school-aged children. Typically resulting in a mild illness characterised by symptoms such as a sore throat, headache,
and fever, GAS infections may also manifest as scarlet fever, presenting with a fine, red rash. Although often manageable, severe cases warrant antibiotic treatment for effective resolution.

An automated, qualitative in vitro diagnostic test employing real-time polymerase chain reaction (PCR) is utilised to detect nucleic acids from Streptococcus pyogenes in human oropharyngeal swabs. This advanced test serves as a valuable aid in diagnosing streptococcal pharyngitis in symptomatic individuals.

Features

Sample Type: Oropharyngeal swabs

Sample Volume: 300 μl

Detection Method: Real-Time PCR

Time to result: Less than 30 minutes

Detectable Pathogen
Streptococcus pyogenes

Vivalytic Group B Streptococcus (GBS) (In Development)

Real-time PCR for the detection of Streptococcus agalactiae – More information to follow

Detectable Pathogen
Streptococcus agalactiae (B-Streptococci)

“AWARD-WINNING DESIGN DELIVERS
AN UNCOMPLICATED USER EXPERIENCE”

Vivalytic Workflow

Intuitive engineering of Vivalytic ensures the analyser is user friendly. The process of patient sample to result comprises a very simple 4 step workflow.

To begin the test, the user scans or enters sample information. The cartridge code is then scanned into the embedded Vivalytic software. The user then adds sample into the dedicated cartridge slot, closes the lid and inserts the cartridge into the Vivalytic.

The touchscreen display will countdown the time remaining to test completion. Results will be displayed on the screen. Multiple Vivalytics can be wirelessly connected allowing the user to control multiple tests at one time all reporting to a master Vivalytic platform.

Download Vivalytic Brochure

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page

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Vivalytic | Candida auris

Vivalytic | Candida auris

 

Detection of Candida auris

*Currently under development. Not available for sale.

Qualitative RT-PCR detection of Candida auris

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    Quick turnaround time of 30 minutes, beneficial for both the patient and for the containment of Candia auris and reducing transmission.

     

     

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    Convenient 4 step process from sample entry to results. Suitable for use in laboratory and non-laboratory settings.

     

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    Real-time PCR enables rapid and targeted detection up to 4 weeks after the onset of symptoms of the multidrug-resistant fungal Candia auris.

Clinical Significance

Candida auris is an emerging and often multidrug-resistant fungal species that poses a significant threat to public health. This yeast-like fungus can cause severe infections, primarily affecting individuals with compromised immune systems, those in healthcare facilities, or those with underlying medical conditions. Candida auris is particularly concerning due to its ability to persist on surfaces, leading to healthcare-associated outbreaks. Diagnosis can be challenging as it is often misidentified with other Candida species. Effective management involves prompt identification, strict infection control measures followed by treatment. The Vivalytic Candida auris test is an automated, qualitative in vitro diagnostic employing real-time PCR to detect Candida auris DNA from swabs taken from the human axilla, groin, nasal, and rectal areas.

This test serves to screen individuals at risk for colonisation, playing a crucial role in the prevention and control of Candida auris outbreaks and infections within healthcare settings.

Features

Sample Type: Swab

Sample Volume: 300 μl

Detection Method: Real-Time PCR

Time to result: 30 minutes

Detectable Pathogens
Candida auris

“AWARD-WINNING DESIGN DELIVERS
AN UNCOMPLICATED USER EXPERIENCE”

Vivalytic Workflow

Intuitive engineering of Vivalytic ensures the analyser is user friendly. The process of patient sample to result comprises a very simple 4 step workflow.

To begin the test, the user scans or enters sample information. The cartridge code is then scanned into the embedded Vivalytic software. The user then adds sample into the dedicated cartridge slot, closes the lid and inserts the cartridge into the Vivalytic.

The touchscreen display will countdown the time remaining to test completion. Results will be displayed on the screen. Multiple Vivalytics can be wirelessly connected allowing the user to control multiple tests at one time all reporting to a master Vivalytic platform.

Download Vivalytic Brochure

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page

Related Products

Viral Respiratory Infection Array

SARS-CoV-2 Pooling Test

Vivalytic

Vivalytic Test Menu


Vivalytic | riTA CT/NG

Vivalytic | riTA CT/NG

 

Detection of Chlamydia trachomatis and Neisseria gonorrhoeae

*Currently under development. Not available for sale.

Qualitative RT-PCR detection of STI causative Species

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    Quick turnaround time of less than 30 minutes, beneficial for both the patient and for the containment of STIs and reducing transmission.

     

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    Convenient 4 step process from sample entry to results. Suitable for use in laboratory and non-laboratory settings.

     

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    Isothermal amplification enables rapid and targeted detection up to 4 weeks after the onset of symptoms and differentiate the STI pathogenic species.

Clinical Significance

Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are bacterial sexually transmitted infections (STIs). Chlamydia, primarily transmitted through sexual contact, is often asymptomatic, necessitating testing for diagnosis. Symptoms may include painful urination, and if untreated, it can lead to complications like pelvic inflammatory disease. Gonorrhoeae, also transmitted sexually, presents symptoms such as painful urination and genital discharge. Early detection is crucial for both infections  to prevent complications and further transmission.

Utilising isothermal nucleic amplification technology, our system qualitatively detects nucleic acids from Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG).

Features

Sample Type: Swab or Urine

Sample Volume: 300 μl

Detection Method: Isothermal amplification

Time to result: Less than 30 minutes

Detectable Pathogens
Chlamydia trachomatis Neisseria gonorrhoeae

“AWARD-WINNING DESIGN DELIVERS
AN UNCOMPLICATED USER EXPERIENCE”

Vivalytic Workflow

Intuitive engineering of Vivalytic ensures the analyser is user friendly. The process of patient sample to result comprises a very simple 4 step workflow.

To begin the test, the user scans or enters sample information. The cartridge code is then scanned into the embedded Vivalytic software. The user then adds sample into the dedicated cartridge slot, closes the lid and inserts the cartridge into the Vivalytic.

The touchscreen display will countdown the time remaining to test completion. Results will be displayed on the screen. Multiple Vivalytics can be wirelessly connected allowing the user to control multiple tests at one time all reporting to a master Vivalytic platform.

Download Vivalytic Brochure

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page

Related Products

Viral Respiratory Infection Array

SARS-CoV-2 Pooling Test

Vivalytic

Vivalytic Test Menu


Growth through medical technology: Randox and Bosch invest heavily in the Vivalytic analysis platform

  • New partnership for Vivalytic analysis platform: Bosch and Randox

  • Laboratories Ltd. to invest 150 million euros in research, development, and

  • distribution

  • Strategic growth field: point-of-care molecular diagnostics expected to

  • become a future market worth billions

  • Growth with fully automated laboratory diagnostics: the two companies aim to

  • achieve sales in the nine-figure range by 2030.

  • Smartphone-sized laboratory: sepsis IVD grade test based on cutting-edge

  • BioMEMS technology is a joint development objective.

With many diseases, every minute counts, and determining whether a patient is presenting the symptoms of a simple cold, the flu, or something as severe as life-threatening meningitis is usually only possible after time-consuming and expensive
laboratory diagnostics. With its Vivalytic analysis platform, Bosch has set itself the goal of making fast and highly precise diagnostics accessible at the point of care – and aims to use molecular diagnostics to become a leading provider in the
market by 2030. To achieve this, Bosch has now agreed on a strategic partnership with Randox Laboratories Ltd., a leading diagnostic and medical technology company. The two companies will invest around 150 million euros in joint research, development, and sales activities for new tests for the Vivalytic analysis platform provided by Bosch Healthcare. One goal is the development of  a sepsis IVD1 grade test that will be the first to feature highly innovative and novel BioMEMS technology.

Bosch has defined medical technology as a strategic growth field. Point-of-care molecular diagnostics is expected to become a future market worth billions. And with its Vivalytic analysis platform, Bosch aims to achieve a leading position in this market. “With cutting-edge technology from our own labs and our own production lines, we want to grow long-term together with partners in the field of precision diagnostics,” says Stefan Hartung, chairman of the Bosch board of management. “Here, our medical technology can draw considerable benefit from our diversification, from our expertise, from the groundwork we have done in automation, miniaturization, molecular diagnostics, and from our experience in microchip development and manufacturing,” Hartung adds. “We are investing long-term in an exciting high-tech growth field and continuously developing it together with partners. With technology ‘Invented for life’, we can relieve the burden on medical professionals and help make the diagnose and treatment of disease faster”.

Shared growth: decentralized diagnostics at the point of care

Bosch Healthcare Solutions and Randox are now joining forces in an attempt to accelerate the development and market launch of new tests and to make distribution channels more efficient. The partnership is set to run for more than ten years. With Vivalytic, the two companies aim to achieve sales in the medium nine-figure range by 2030. “Globally, healthcare is moving toward decentralized and personalized diagnostics, that enable rapid interventions and individual treatment plans,” says Marc Meier, managing director of Bosch Healthcare
Solutions GmbH. “With our partner Randox, we want to further expand the test portfolio of our Vivalytic analysis device. Our fully automated molecular diagnostics PCR tests provide clarity directly at the site of sample collection,
shorten waiting times, and take the strain off the healthcare system,” Meier adds. The two partners are a good fit: Bosch can contribute its technology and manufacturing expertise across the fields of molecular diagnostics, microchip
development and manufacturing, and miniaturization. The universal Vivalytic platform for molecular diagnostics was developed in over ten years by Bosch researchers and brought to market maturity by Bosch Healthcare Solutions. Randox has 40 years of experience in the design and development of highly sensitive IVD tests performed on a variety of technologies, including microfluidic platforms. In combination with the company’s extensive market knowledge and global sales and distribution network, this adds up to considerable opportunities for growth. “Randox has always been committed to improving health worldwide and sees the need to invest in research and development initiatives that will support clinical decision making across a variety of disease areas. Diagnostics has always been an indispensable component of healthcare, and the alignment of both science and technology makes for the perfect fit in an area for high potential impact, especially in pressure-driven environments,” says Dr. Peter Fitzgerald, Managing Director of Randox Laboratories Ltd. Bosch Healthcare Solutions and Randox already collaborated during the Covid-19 pandemic. In spring 2020, Bosch launched one of the world’s first fully automated PCR tests for the SARS-CoV-2 coronavirus. Together with Randox, the rapid test for use in doctor’s offices, nursing homes, testing stations, and hospitals was made ready for the Vivalytic analysis device within the space of just a few weeks.

Development goal: sepsis test based on BioMEMS technology

One focus of the development partnership with Randox is the implementation of a highly sensitive multiplex2test for sepsis on the Vivalytic analysis platform.Sepsis, also known as “blood poisoning,” is a potentially life-threatening complication3 that can occur in conjunction with various infectious diseases. A medical emergency that can lead to multiple organ failure, it requires immediate medical treatment. The planned IVD grade sepsis test is to be based for the first time on the highly innovative and novel BioMEMS technology developed by teams from Bosch corporate research in Renningen and Bosch Healthcare Solutions in Waiblingen. “We have set ourselves the ambitious goal
of adding the functions of a high-performance silicon chip based on microsystems technology to our test cartridges for the Vivalytic platform. In doing so, we will combine Bosch’s unique expertise in the areas of MEMS chips, molecular diagnostics, and microfluidics,” Marc Meier says. “Clinical outcomes in sepsis depend on timely diagnosis and appropriate early therapeutic intervention. Current methods of sepsis diagnosis are insufficient and time-consuming. With over 10 years of experience in the field of infectious diseases diagnostics, we aim to develop a state-of-the-art sepsis test using the highly multiplexing BioMEMS technology. Such a test could revolutionize sepsis diagnosis, ultimately leading to improved treatment outcomes and lower mortality rates from this life-threatening condition,” says Dr. Peter Fitzgerald.

Smaller and faster: from microfluidics to nanofluidics – thanks to BioMEMS

The powerful BioMEMS chip adds a further innovative analysis method to the Vivalytic test cartridge, enabling it to test simultaneously and significantly faster for a large number of different pathogens. It is called BioMEMS because it combines microelectromechanical systems (MEMS) with microfluidics for applications in the field of medical technology. In microfluidics, very small amounts of fluid in the microliter range are moved in a very small space. Miniaturization allows qualitative biochemical polymerase chain reactions (PCR) to run in parallel in real-time on a single BioMEMS chip. “Compared to previous PCR reactions, the volumes of liquids are reduced by a factor of 1,000 to the nanoliter range. The analysis of liquids is left to a small microchip,” Marc Meier explains. With the new BioMEMS technology, fully automatic testing up to 250 genetic characteristics4 (e.g. pathogens) in one cartridge is possible in less
than 15 minutes. The test cartridge is a highly complex laboratory the size of a smartphone, so to speak. Another future advantage of BioMEMS will be simpler and faster adaptation of new tests or existing tests on the chip itself. For example, existing tests can easily be expanded to include additional features. “The BioMEMS technology paves the way for us to move into nanofluidics, where each pathogen will be examined in a reaction vessel the thickness of a hair,” Meier says. To achieve this, Bosch wants to create more capacity on a MEMS chip and expand it what are known as “nanocavities”. Thanks to t

hese very small cavities, even more biochemical processes will be able to run in parallel on a
chip. With increasing miniaturization, the technology has potential to be used in oncology as well over the long term. The BioMEMS chips are to be manufactured at the Bosch semiconductor plant in Reutlingen, with bio-integration and cartridge
assembly to be carried out at Bosch Healthcare Solutions in Waiblingen.

Vivalytic platform: easy application at the point of sample collection

The advantages of carrying out PCR tests on the Bosch Vivalytic platform lie not only in speedy a

nalysis, but also in the ease of use: Once the sample has been taken, it is placed in the test cartridge. The cartridge, which contains all the necessary reagents for the respective test, is then inserted into the Vivalytic analyser for automated evaluation. Medical staff require only brief training on how to operate it. This enables fast and targeted diagnostics directly at the point of sample collection – either at the doctor’s office or in the hospital – without the often long and time-consuming detour via a central laboratory. Bosch Healthcare Solutions already distributes various tests for diseases of the upper and lower respiratory tract, such as SARS-CoV-2 – also a pooling variant and as a saliva test – or a test to differentiate between SARS-CoV-2, RSV virus and influenza. There are also tests for pathogens that cause sexually transmitted infections (STI) and MRSA / SA (“hospital germ”). Starting in summer, it is planned to expand the portfolio with tests for whooping cough (Bordetella holmesii, Bordetella parapertus

sis, and Bordetella bronchiseptica), urinary tract infections (UTI), bacterial meningitis, the two most common sexually transmitted diseases (Chlamydia trachomatis; CT and Neisseria gonorrhoeae; (NG), fungal infections (Candida auris), and three tests for diarrheal diseases
(norovirus, Clostridioides difficile, HSP)

Contact persons for press inquiries:

Robert Bosch GmbH
Dörthe Warnk, Phone: +49 711 811-55508
E-mail: doerthe.warnk@bosch.com

Randox Laboratories Ltd.


Martin Conway, Phone: +44 (0) 28 9442 2413
E-mail: martin.conway@randox.com

 


Vivalytic | Bacterial Meningitis

Vivalytic | Bacterial Meningitis

 

Rapid Detection of bacterial pathogens associated with Meningitis

*Currently under development. Not available for sale.

Qualitative RT-PCR detection of bacterial pathogens associated with Meningitis

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    Compared to the time-consuming traditional procedures, Vivalytic’s quick turnaround time of 30 minutes allows for the prompt and specific antibiotic treatment to be initiated immediately

     

     

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    Convenient 4 step process from sample entry to results. Suitable for use in laboratory and non-laboratory settings

     

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    Detection from a small CSF sample of only 200μl

Clinical Significance

Bacterial meningitis is an infectious disease characterised by infection and inflammation of the meninges, which leads to significant morbidity and mortality worldwide. Even with early diagnosis and proper treatment, 8-15% of patients succumb to the disease within 24 to 48 hours of symptom onset. While meningitis can affect individuals of all ages, young children face the greatest risk. Newborns are particularly vulnerable to Group B streptococcus, while meningococcus, pneumococcus, and Haemophilus influenzae pose higher risks for young children. Young adults and adolescents are prone to meningococcal disease, whereas the elderly are at a higher risk of pneumococcal disease.

The Vivalytic Bacterial Meningitis panel provides the capability to identify six bacterial pathogens implicated in meningitis from a single test, improving screening processes and lowering costs. With minimal steps from sample collection to result, screening for meningitis on the Vivalytic is the most effective wait to contain and prevent spread, requiring no additional further lab equipment.

 

Features

Sample Type: Cerebral Spinal Fluid (CSF)

Sample Volume: 200 μl

Detection Method: Real-Time PCR

Time to result: 30 minutes

Detectable Pathogens
Escherichia coli K1 Neisseria meningitidis
Haemophilus influenzae Streptococcus agalactiae
Listeria monocytogenes Streptococcus pneumoniae

Viral Meningitis (In Development)

Real-time PCR test for the detection of pathogens related to Viral Meningitis – More information to follow

Detectable Pathogens
HSV1/HSV2 VZV
Enterovirus

“AWARD-WINNING DESIGN DELIVERS
AN UNCOMPLICATED USER EXPERIENCE”

Vivalytic Workflow

Intuitive engineering of Vivalytic ensures the analyser is user friendly. The process of patient sample to result comprises a very simple 4 step workflow.

To begin the test, the user scans or enters sample information. The cartridge code is then scanned into the embedded Vivalytic software. The user then adds sample into the dedicated cartridge slot, closes the lid and inserts the cartridge into the Vivalytic.

The touchscreen display will countdown the time remaining to test completion. Results will be displayed on the screen. Multiple Vivalytics can be wirelessly connected allowing the user to control multiple tests at one time all reporting to a master Vivalytic platform.

Download Vivalytic Brochure

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page

Related Products

Viral Respiratory Infection Array

SARS-CoV-2 Pooling Test

Vivalytic

Vivalytic Test Menu


Vivalytic | Urinary Tract Infection

Vivalytic | UTI Rapid Test RUO

 

Rapid multiplex detection of common urinary tract infections

UTI testing made simple

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    Quick turnaround time of less than 130 minutes compared to 72 hours minimum for standard urine culture, beneficial for both the patient and for the containment of the most common UTIs
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    Convenient 4 step process from sample entry to results. Suitable for use in laboratory and non-laboratory settings

     

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    Detect 21 different uropathogens and identify the presence of 7 antimicrobial resistance genes all from one single urine sample

Clinical Significance

Urinary tract infections (UTIs) are highly prevalent infections acquired both in the community and hospital settings. The widespread use of antibiotics has led to an alarming rise in UTIs caused by organisms that are resistant to multiple drugs, affecting approximately 150 million people worldwide each year.

UTIs can be categorised as either uncomplicated or complicated, depending on various factors such as anatomical or functional abnormalities within the urinary tract, comorbidities, recurrent UTIs, catheter-associated UTIs, and urosepsis.

A single native urine sample, along with the Vivalytic PCR-based assay, for simultaneous qualitative detection of causative UTI bacterial and fungal pathogens can detect 21 different uropathogens and identify the presence of 7 antimicrobial resistance genes, allowing for a swift and effective treatment plan to begin. With a rapid time-to-result and capable of identifying a multitude of bacterial targets, the UTI panel on Vivalytic leads to improved patient outcomes and effective management of urinary tract infections.

R&D project manager Dr Heather McMillan discusses the importance of diagnostics in the treatment of UTI’s.

Features

Sample Type: Native Urine

Sample Volume: 300 μl

Detection Method: Randox Biochip Technology (end-point PCR)

Time to result: Less than 130 minutes

Detectable Pathogens
GRAM-NEGATIVE BACTERIAL SPECIESGRAM-POSITIVE BACTERIAL SPECIESYEASTANTIMICROBIAL RESISTANCE GENES
Acinetobacter baumanniiEnterococcus faecalisCandida albicansTRIMETHOPRIM RESISTANCE
Citrobacter freundiiEnterococcus faeciumdfrA1
Citrobacter koseriStaphylococcus aureusdfrA5
Enterobacter cloacaeStaphylococcus epidermidisdfrA7&17
Escherichia coliStaphylococcus saprophyticusdfrA12
Klebsiella aerogenesStreptococcus agalactiaeMETHICILLIN RESISTANCEVANCOMYCIN RESISTANCE
Klebsiella oxytocamecA
Klebsiella pneumoniaeVancomycin Resistance
Morganella morganiivanA
Proteus spp.vanB
Providencia rettgeri
Providencia stuartii
Pseudomonas aeruginosa
Serratia marcescens

“AWARD-WINNING DESIGN DELIVERS
AN UNCOMPLICATED USER EXPERIENCE”

Vivalytic Workflow

Intuitive engineering of Vivalytic ensures the analyser is user friendly. The process of patient sample to result comprises a very simple 4 step workflow.

To begin the test, the user scans or enters sample information. The cartridge code is then scanned into the embedded Vivalytic software. The user then adds sample into the dedicated cartridge slot, closes the lid and inserts the cartridge into the Vivalytic.

The touchscreen display will countdown the time remaining to test completion. Results will be displayed on the screen. Multiple Vivalytics can be wirelessly connected allowing the user to control multiple tests at one time all reporting to a master Vivalytic platform.

Download Vivalytic Brochure

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page

Related Products

Viral Respiratory Infection Array

SARS-CoV-2 Pooling Test

Vivalytic

Vivalytic Test Menu


Vivalytic | Rota-, Norovirus & C. diff

Vivalytic | Rota-, Norovirus & C. diff

 

Rapid Detection of Rota-, Norovirus & C. diff Infections

Currently under development. Not available for sale.

Qualitative RT-PCR detection of Rota-, Norovirus & C. diff

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    Quick turnaround time of less than 60 minutes, beneficial for both the patient and for the containment of Rota-, Norovirus & C. diff

     

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    Convenient 4 step process from sample entry to results. Suitable for use in laboratory and non-laboratory settings

     

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    Detection from liquid or soft human stool specimens to distinguish between C. difficile, norovirus and rotavirus and delivers fast and precise results.

Clinical Significance

Gastroenteritis refers to the inflammation of the stomach, small intestine, and large intestine. The majority of acute gastrointestinal illnesses (AGIs) are caused by viruses like Norovirus or Rotavirus, as well as bacterial pathogens such as Clostridioides difficile (C. difficile).

The Vivalytic Rota-, Norovirus and C. difficile Panel is capable of detecting these three common gastrointestinal pathogens. With a rapid and accurate time-to-result, this state-of-the-art test enables swift identification of multiple targets,  leading to improved patient outcomes and efficient management of gastrointestinal illnesses.

Features

Sample Type: Swab samples from liquid or soft human stool specimens

Sample Volume: 300 μl

Detection Method: Real-time PCR

Time to result: Less than 60 minutes

Detectable Pathogens
Rotavirus type ANorovirus (genogroup I/II) C. difficile genes (tcdA/tcdB)

“AWARD-WINNING DESIGN DELIVERS
AN UNCOMPLICATED USER EXPERIENCE”

Vivalytic Workflow

Intuitive engineering of Vivalytic ensures the analyser is user friendly. The process of patient sample to result comprises a very simple 4 step workflow.

To begin the test, the user scans or enters sample information. The cartridge code is then scanned into the embedded Vivalytic software. The user then adds sample into the dedicated cartridge slot, closes the lid and inserts the cartridge into the Vivalytic.

The touchscreen display will countdown the time remaining to test completion. Results will be displayed on the screen. Multiple Vivalytics can be wirelessly connected allowing the user to control multiple tests at one time all reporting to a master Vivalytic platform.

Download Vivalytic Brochure

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page

Related Products

Viral Respiratory Infection Array

SARS-CoV-2 Pooling Test

Vivalytic

Vivalytic Test Menu


Vivalytic | Norovirus

Vivalytic | Norovirus

 

Rapid Detection of Norovirus Infection

*Currently under development. Not available for sale.

Qualitative RT-PCR detection of Norovirus

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    Quick turnaround time of less than 60 minutes, beneficial for both the patient and for the containment of Norovirus

     

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    Convenient 4 step process from sample entry to results. Suitable for use in laboratory and non-laboratory settings

     

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    Detection from liquid or soft human stool specimens

Clinical Significance

Noroviruses, often referred to as winter-vomiting disease or stomach flu, are notorious for their rapid spread among human populations, particularly during the winter season. They are highly contagious and account for the majority of gastrointestinal infections. On the other hand, Rotaviruses are responsible for severe diarrheal illness, primarily affecting infants and young children. Transmission of these pathogens commonly occurs within healthcare institutions, including patient-to-patient contact, contaminated hands of healthcare workers, or through environmental contamination.

The Vivalytic Norovirus Panel, specifically engineered to detect the presence of Norovirus (genogroup I/II) in various clinical specimens to facilitate streamlined healthcare practices. By empowering healthcare providers with advanced capabilities, this diagnostic tool enhances their ability to combat Norovirus infections and implement necessary preventive measures in various settings, including hospitals, long-term care facilities, and schools.

Features

Sample Type: Swab samples from liquid or soft human stool specimens

Sample Volume: 300 μl

Detection Method: Real-time PCR

Time to result: Less than 60 minutes

Detectable Pathogens
Norovirus (genogroup I/II)

“AWARD-WINNING DESIGN DELIVERS
AN UNCOMPLICATED USER EXPERIENCE”

Vivalytic Workflow

Intuitive engineering of Vivalytic ensures the analyser is user friendly. The process of patient sample to result comprises a very simple 4 step workflow.

To begin the test, the user scans or enters sample information. The cartridge code is then scanned into the embedded Vivalytic software. The user then adds sample into the dedicated cartridge slot, closes the lid and inserts the cartridge into the Vivalytic.

The touchscreen display will countdown the time remaining to test completion. Results will be displayed on the screen. Multiple Vivalytics can be wirelessly connected allowing the user to control multiple tests at one time all reporting to a master Vivalytic platform.

Download Vivalytic Brochure

Want to know more?

Contact us or visit our COVID-19 Monitoring & Management page