Improving stroke diagnoses with Randox Biosciences
A stroke can happen to anyone at any time. It is a serious life-threatening medical condition which occurs when the blood supply to part of the brain is cut off. It causes the brain cells to die resulting the abilities controlled by the brain such as memory and muscle control to become damaged. 1
According to the Stroke Association, strokes are considered the fourth biggest killer in the UK. There are more than 100,000 strokes each year which equals around one stroke every five minutes.2 Some people recover from the condition; however, two thirds of the survivors will have some sort of disability. 3
There are two mains types of strokes which are defined as “Ischemic strokes” and “Hemorrhagic stroke”.
Ischemic stroke is by far the most common kind of stroke, accounting for about 88% of all cases4. Ischemic strokes occur when there is an artery blockage which cuts off the blood supply to certain areas of the brain, which then results in brain cells being unable to make energy and dying. The arteries are vital for the brain as they bring fresh blood from the heart and lungs carrying oxygen and nutrients and taking away carbon dioxide and cellular waste. 4
The hemorrhagic stroke is less common but is more severe as there is a higher risk of dying within the first three months. It is when a blood vessel ruptures causing a bleed inside the brain, resulting in the death of brain cells. They are responsible for 40% of all stroke deaths.5
Symptoms of Stroke
The most commons symptoms of a stroke are:
- Weakness or numbness of the face, arm, or leg on one side of the body
- Loss of vision or dimming in one or both eyes
- Loss of speech, difficulty talking, or understanding what others are saying
- Sudden, severe headache with no known cause
- Loss of balance or unstable walking, usually combined with another symptom
Many risk factors can increase your chance of having a stroke. Some life style factors include being obese/overweight, not exercising enough, heavy drinking, use of illegal drug such as cocaine, cigarette smoking, high cholesterol, diabetes, disruptive sleeping pattern and family history of having stroke or heart attack.
Up to 80% of strokes are preventable. 3 There are simple healthy lifestyle recommendations that could decrease your chances of developing a stroke in the future which include:
- Controlling your blood pressures as it is one of the biggest preventions of developing a stroke.
- Maintaining a healthy weight through a well-balanced diet involving rich fruit and vegetables as well as decreasing the amount of cholesterol, saturated fat and sodium intake.
- Exercising regularly and staying within a good routine will also reduce your risk of having a stroke.
- Quitting tobacco usage and decreasing alohcal intake will help as well as regular usage increases the risk of having high blood pressure.
- Avoid taking illegal drugs such as cocaine as it reduces your blood flow which narrows the arteries.
Randox Biosciences offers a stroke array which works quickly to determine which type of stroke a person has experienced. Ischaemic stroke can be treated by thrombolysis and, with early usage, it can help limit stroke damage and disability.
However, inappropriate administration of thrombolytic therapy can cause serious adverse effects, including intracranial haemorrhage. Hence, there is an unmet clinical need for a rapid and highly sensitive testing that complements existing CT scanning approaches and facilitate the definitive identification of ischaemic stroke patients.
Randox’s innovative Biochip Array Technology enables simultaneous detection of eight stroke biomarkers from a single blood sample.
The eight biomarkers that can be detected in a single blood sample are:
- Glutathione S-Transferase-Pi (GSTP-Pi)
- Nucleoside Diphosphate Kinase A (NDKA)
- Parkinson Protein 7 (PARK7)
- Glial Fibrillary Acidic Protein (GFAP)
- Interleukin 6 (IL-6)
- Heart Fatty Acid Binding Protein (H-FABP)
This year, National Brain Awareness Week runs from the 11th onto the 15th March 2019; a full week dedicated to brain health to increase public awareness of the progress and research of brain health.
Every single brain is unique and therefore, there are no two brains that are alike. The brain is an incredible and powerful organ which works throughout your life – starting from the womb to the end. It controls your body functioning in response to processing new information, developing new experiences and allowing you to understand and interact with the world. It contains one hundred billion nerve cells or neurons and each of the neurons can contact thousands of other cells via tiny structures called synapses. Our brains form a million new connections for every second of our lives.1
There are many conditions which can affect the brain including brain injuries, cerebrovascular injuries such as strokes or brain tumors, neurodegenerative disorders such as dementia or Parkinson’s disease, or even psychological conditions.
There is increasing evidence that the choices we make in life can have significant impacts on the health of our brain and bodies as we grow older. Doctors and scientific researchers have discovered that it’s possible to improve brain health and reduce the risk of dementia and age-related cognitive decline by making simple yet small lifestyle changes – for example, improving your physical exercise.
Physical experience is not only good for the heart but also has a positive impact on the brain as well. People who exercise regularly have a lower risk of developing Alzheimer’s disease as exercise improves blood flow and memory. Another way to improve your brain health is to get your eight hours of sleep. Poor sleeping patterns can increase your chances of developing the brain conditions highlighted above. Also, eating well and eating foods that improve brain function will go a long way – for example, berries, fish, turmeric, green tea, avocado, walnuts and even dark chocolate.
Caroline Abrahams, Director of Age UK said: ‘The changes that we need to make to keep our brains healthy are already proven to be good for the heart and overall health, so it’s common sense for us all to try to build them into our lives.’ 3
Randox Biosciences offers the Apolipoprotein E4 (ApoE4) Array. The Apolipoprotein E4 (ApoE4) Array is a research use-only product developed for the Evidence Investigator. The ApoE4 Array measures both total ApoE protein levels and ApoE4 protein levels directly from plasma samples and by using a ratio it can classify patients as negative or positive for ApoE4. In turn we can then assess their risk for the development of Alzheimer’s disease.
For further information about the Randox Alzheimer’s Array or our Evidence Investigator, please email firstname.lastname@example.org