Veterinary Diagnostic Solutions
Veterinary Diagnostic Solutions
Comprehensive Clinical Packages for Veterinary Laboratories
Benefits of the Randox Veterinary Diagnostic Solutions
Validated for use
The Randox veterinary diagnostic solutions are scientifically proven and validated for use with a diverse range of animal species.
Encompassing diagnostic reagents, internal & external quality control, and the RX series of clinical chemistry analysers.
Applications available detailing instrument-specific settings for the convenient use of the Randox veterinary reagents on a variety range of clinical chemistry analysers.
Analysers for all laboratories
With a range of semi-automated and automated analysers, the RX series offers versatility to suit the needs of all laboratory requirements.
Small Sample Volume
Veterinary testing is one of Randox’s specialities and the RX series caters for smaller animals where samples can be harder to obtain with volumes ranging from 0.5 – 5μl.
Superior Performance & Unique Tests
A range of superior performance & unique tests, offering veterinary laboratories choice, quality and innovation.
With almost 40 years’ experience in veterinary diagnostics – we can help!
Clinical Chemistry Analysers
Offering the world’s largest veterinary test menu, the RX series provides laboratories with maximum analyser up-time combined with precise, reliable and accurate results. With a diverse range of versatile semi-automated and fully automated analysers, the RX series suits the needs of all laboratory sizes with unrivalled correlation to gold-standard methodologies.
Offering an extensive veterinary test menu, encompassing 48 open channel diagnostic assays which are internationally recognised as being of the highest quality, producing accurate and precise results. All our assays are validated against gold-standard methods, offering low CV’s and excellent precision giving you the confidence that you are sending out the correct patient results.
Internal Quality Control
As one of the largest manufacturers of true third party quality control solutions, Randox produce high quality materials that can help streamline laboratory procedures whilst saving time and money. With over 390 parameters available in our Acusera Internal Quality Control range, choice and flexibility is guaranteed. You can rely on Randox to deliver trustworthy results time and time again.
External Quality Assessment
Randox International Quality Assessment Scheme (RIQAS) is the world’s largest external quality assessment (EQA) scheme. Currently offering 33 programmes, RIQAS has more than 45,000 laboratory participants in over 130 countries. Delivering a comprehensive yet cost effective EQA solution, RIQAS will help meet regulatory requirements and increase confidence in test system accuracy.
Diagnostic Veterinary Reagents
RX series Clinical Chemistry Analysers
The NEW VeraSTAT-V
HORSE HEALTH IN STABLE HANDS
A Stable-Side Device To Monitor Inflammation
The latest edition to our Veterinary diagnostics portfolio is the NEW Randox VeraSTAT-V, a small footprint stable-side device designed to detect early signs of inflammation by measuring quantitative levels of Serum Amyloid A in whole blood, quickly and accurately.
> Detects inflammation
> Convenient stable-side device
> Results in 6 minutes
> Quantitative results
> Easy to use
> Results stored
> Whole blood
Equine Serum Amyloid A: A Valuable Inflammatory Marker
Serum Amyloid A (SAA) is a protein the liver produces in response to inflammation. SAA is released into the bloodstream to help the immune system fight infection. SAA is the fastest marker to rise in response to inflammation making it a valuable marker for detection.
The ability to accurately detect infection in as little as 6 minutes, and from the convenience of the stable yard, is beneficial to both horse and owner. Treatment can be started immediately; recovery time can be shorter and the horse can return to work earlier.
SCREEN, DETECT, PROTECT: Infection is invisible, detection isn’t
Starting at base
A healthy horse’s SAA levels are low or even undetectable. Inflammatory conditions increase the levels of SAA by up to 1000 times the baseline level, so understanding SAA levels delivers valuable insight.
The horse’s liver responds to infection in as little as 6 HOURS and SAA is released into the blood to help fight the infection. Early diagnosis means that you can ACT FAST to shorten recovery time.
SAA levels stay elevated until the infection subsides. Monitoring SAA levels over time, will track how long the infection persists and answer the question, ‘Is the treatment working?’
Indicator treatment is NOT working
SAA levels should decrease following treatment, therefore continued heightened levels of SAA may be an indicator that the treatment has not worked, and an alternative treatment may be required.
Useful Veterinary Resources
Veterinary RX Series
Veterinary Diagnostic Reagents
High Quality Open Channel Tests, Validated For Veterinary Use
Benefits of Randox Diagnostic Veterinary Reagents
Comprehensive Test Menu
A comprehensive test menu encompassing 48 diagnostic veterinary assays, including a variety of assays unique to Randox
Superior methodologies ensuring accurate & reliable results compared to traditional methods
Versatile test menu enabling laboratories to reduce costs with in-house testing
Excellent correlations to gold standard & commercial methods, providing confidence in patient results
Validated For Use
The Randox diagnostic veterinary reagents are scientifically proven and validated for use with a diverse range of animal species
Applications available detailing instrument-specific settings for the convenient use of Randox Veterinary Reagents on a variety of clinical chemistry analysers
Open Channel Diagnostic Veterinary Reagents
|Alanine Aminotransferase (ALT)||Cholesterol (LDL)||GLDH||Phosphorus (Inorganic)|
|Aldolase||Cholinesterase (Butyryl)||Glutathione Peroxidase (Ransel)||Sodium|
|Alkaline Phosphatase||CK-NAC||Glutathione Reductase||Superoxide Dismutase (Ransod)|
|Ammonia||CO2 Total||Iron||Total Antioxidant Status (TAS)|
|Amylase||Copper||Lactate||Total Iron Binding Capacity (TIBC)|
|Aspartate Aminotransferase (AST)||Creatinine||Lactate Dehydrogenase (L-P)||Total Protein|
|Bile Acids (4th Gen)||CRP (Canine)||Lactate Dehydrogenase (P-L))||Triglycerides|
|Bile Acids (5th Gen)||D-3 Hydroxybutyrate (Ranbut)||Lipase||Urea|
|Bilirubin (Direct)||Ferritin||Magnesium||Uric Acid|
|Bilirubin (Total)||Fructosamine||Microalbumin||Urinary Protein|
|Cholesterol (HDL)||Gamma GT||NEFA||Zinc|
|Aldolase||CRP (Canine)||Glutathione Peroxidase (Ransel)||Superoxide Dismutase (Ransod)|
|Bile Acids (5th Gen)||Creatinine (Enzymatic)||Glutathione Reductase||Total Antioxidant Status (TAS)|
|Copper||D-3-Hydroxybutyrate (Ranbut)||Non-Esterified Fatty Acids (NEFA)||Zinc|
Product availability may vary from country to country. Some product may be for Research use Only. For more information on product application and availability, please contact your local Randox Representative.
Superior Performance & Unique Diagnostic Veterinary Reagents
Copper is one of the several essential trace elements in animal life required for red and white blood cell formation, healthy nerve fibres, pigmentation, wool growth and bone growth 1. In animals, whilst copper deficiency is one of the most commonly diagnosed trace element deficiencies, over-supplement of copper can lead to copper toxicity 2.
Copper deficiency is common in bovines, mainly cattle and sheep, caused by two factors: low copper levels in plants in copper-deficient soils, and an induced deficiency due to ingesting excessive levels of other elements, including: sulphur, iron and molybdenum in feed supplements or pastures 1.
On the other hand, bovines such as sheep and calves prior to weaning are the most susceptible to copper toxicity. This can occur as a result over excessive ‘therapeutic’ amounts of copper are added to the feed to avoid copper deficiency, however, it’s more commonly the result of long-term ingestion of copper in quantities which exceed the nutritional requirements 3.
Diabetes mellitus (DM), is commonly observed in middle aged and older canines and felines. Certain conditions predispose canines and felines to DM, including being overweight, inflammation of the pancreas, and certain medications which interfere with insulin, such as glucocorticoids. DM can also occur in the young which is attributed to a genetic factor. DM is more commonly observed in female canines and male felines 4.
Fructosamine testing is utilised to evaluate a canine or feline’s response to treatment which provides the canine or feline’s average glucose concentrations for the previous 7 to 14 days 5.
The NBT method is commonly utilised in fructosamine testing, however Randox offer the enzymatic method which improves specificity and reliability. The Randox enzymatic fructosamine assay displayed a correlation coefficient of r=0.9192 when compared to the NBT method.
Non-esterified fatty acids (NEFA) reflects the energy status of animals, with high NEFA concentrations indicating a negative energy balance. A negative energy balance occurs when caloric intake is lower than energy expenditure. High serum NEFA concentrations and a negative energy balance are risk factors for metabolic disease 6.
Energy balance is one of the most critical nutritional factors affecting animal health, reproductive performance and lactation 7. A negative energy balance has been observed in several animal species and should be observed especially in bovine (cattle, goats, sheep), feline and equines.
Superoxide dismutase (SOD) is an enzyme responsible for catalysing the dismutation of superoxide radicals (O2-), a primary reactive oxygen species (ROS) produced by the body, to hydrogen peroxidase (H2O2) and molecular oxygen (O2), the inadvertent by-products of aerobic metabolism. Consequently, SOD plays an integral role in protecting the body from oxidative stress 8, 9, 10.
SOD measurement is particularly useful in endurance horses as oxidative stress increases with prolonged endurance training. Decrease levels of SOD can cause fatigue, muscle damage, stiffness, and decreased performance 11.
SOD measurement is also useful in dairy cows who experience oxidative stress and a reduce antioxidant defence capacity during postpartum period and lactation 12.
Zinc is an essential trace mineral in animals and is required for the normal functioning of organisms. Involved in several biochemical processes, including: RNA and DNA expression and cellular use of oxygen and respiration, sequestration of free radicals, protection against lipid peroxidation and maintenance of cell membrane integrity 13.
In canines, zinc is not easily or readily absorbed in the intestines. The absence of zinc in canines causes various abnormalities affecting the immune system, metabolic function and the skin. Moreover, zinc deficiency can cause zinc responsive dermatosis, a keratinisation disorder (abnormal skin production) 14.
Zinc toxicity has been observed in exotic, large and wild animals due to dietary indiscretions. Zinc toxicity causes decreased weight and milk production in large animals and lameness and epiphyseal in foals 15.
RX series Clinical Chemistry Analysers
 Van Saun RJ. Food Animal Practice. : Saunders WB; 2009. http://www.sciencedirect.com/science/article/pii/B9781416035916100405 (accessed 11 November 2019).
 Erickson E. Copper deficiency in sheep and cattle. https://www.agric.wa.gov.au/feeding-nutrition/copper-deficiency-sheep-and-cattle (accessed 11 November 2019).
 NADIS Animal Health Skills. Chronic Copper Toxicity. https://www.nadis.org.uk/disease-a-z/cattle/chronic-copper-toxicity/ (accessed 11 November 2019).
 Bidewell C, Livesey C. Copper poisoning: an emerging disease in dairy cattle. Veterinary Laboratories Agency ; (): 16-19. https://pdfs.semanticscholar.org/6282/64c8b58d44018a5527d5a58162e0bdf82e95.pdf (accessed 11 November 2019).
 Siddique T, Deng HX, Ajroud-Driss S. Motor Neuron Disease. Rimoin D, Pyeritz R, Korf B (eds). Emery and Rimoin’s Principles and Practice of Medical Genetics, 6th ed. : Elsevier Ltd; 2013. pp. 1-22.
 Homma T, Fujii J. Oxidative Stress and Dysfunction of the Intracellular Proteolytic Machinery: A Pathological Hallmark of Nonalcoholic Fatty Liver Disease. Watson RR, Preedy VR (eds). Dietary Interventions in Liver Disease, 1st ed. : Elsevier Inc; 2019. pp. 59-70.
 Siqueira RF, Weigel RA, Nunes GR, Mori CS, Fernandes WR. Oxidative profiles of endurance horses racing different distances. Brazilian Journal of Veterinary and Animal Sciences 2014; 66(2): 455-461.
 Feştilă I, Mireşan V, Răducu C, Cocan D, Constantinescu R. Evaluation of Oxidative Stress in Dairy Cows through Antioxidant Enzymes Glutathione Peroxidase (GPX) and Superoxide Dismutase (SOD) . Bulletin UASVM Animal Science and Biotechnologies 2012; 69(1-2): . http://journals.usamvcluj.ro/index.php/zootehnie/article/download/8396/7617 (accessed 21 Nov 19).
 Cahill-Morasco R. Overview of Zinc Toxicosis. https://www.msdvetmanual.com/toxicology/zinc-toxicosis/overview-of-zinc-toxicosis (accessed 21 November 2019).
Canine infection test redesigned to create less laboratory wastage
A new smaller veterinary test kit for the diagnosis of viral and bacterial infections in dogs has been unveiled by global diagnostics company Randox Laboratories.
Suitable for the testing of a wide range of breeds, the test, which monitors levels of C-Reactive Protein (CRP) produced by the liver in response to inflammation, infection and tissue injury, has been redesigned in a smaller size to reduce consumable wastage.
Randox Canine CRP can diagnose conditions such as pancreatitis (inflammation of the pancreas), cystitis (a bladder infection) and inflammatory bowel disease, and can also be used to establish if a dog is pregnant.
Lynsey Adams, Randox Clinical Marketing Manager, commented;
“The redesign of our Canine CRP kit size, which has reduced the volume of the CRP reagent for the diagnosis of canine infection, means that laboratories will produce less waste, and ultimately, be more cost-effective.
“The wide measuring range of this test allows for slight variations of normal ranges across different canine species and ensures accurate results for all breeds.”
Concentration levels of CRP elevate in the blood of canines much earlier post-injury or infection than other biomarkers. This rapid response following trauma (usually within 4 to 6 hours), as well as the fact that CRP levels return to normal quickly at the end of an acute episode, make Canine CRP useful for both the detection of acute inflammation episodes and the monitoring of its treatment, such as steroids or antibiotics.
“As in humans, CRP is used as a marker of inflammatory activity, but with the Randox Canine CRP test, which uses the same high-quality materials as our human assay, CRP can also be tested in dogs to establish a range of viral and bacterial infections.
“As CRP in healthy dogs is present in low concentrations (5 mg/dl), but can elevate to 600 mg/dl, testing for this biomarker can not only detect inflammation but also provide information on its severity.”
The new test from Randox enhances an already comprehensive veterinary test menu of high performance and superior animal health assays including Bile Acids, D-3 Hydroxybutyrate (Ranbut), Glutathione Peroxidase (Ransel) and Total Antioxidant Status, for agriculture and livestock, companion animals, university and research institutes, and the sports industry.
Randox veterinary solutions also include quality control, external quality assessment (EQA) and the RX series range of clinical chemistry analysers.
“We have over 30 years’ experience as a supplier to the veterinary market and are proud to be able to offer veterinarians and other professionals in the animal health industry, tests which are of the highest quality, accuracy and efficiency.
“Offering the complete veterinary diagnostics package of clinical chemistry analysers, reagents, and quality control, Randox is transforming the landscape of veterinary diagnostics, by providing a time and cost effective, flexible and versatile approach to animal health testing.”
Benefits of the new Randox Canine CRP Kit
- Immunoturbidimetric method.
- New kit size – R1 2 x 18.1ml, R2 2 x 5ml offering efficiencies in cost and reagent wastage.
- Wide measuring range of 0.8 – 220mg/dl for the comfortable detection of clinically important results. CRP in healthy dogs can be found at levels below 35 mg/L, therefore Randox Canine CRP comfortably detects abnormal levels.
- In addition, a wide measuring range allows for slight variations of normal ranges across different canine species and ensures accurate results for all.
- Liquid ready-to-use reagents for convenience and ease of use.
- Calibrator included in the kit offering a cost effective canine CRP testing solution.
- Dedicated canine CRP controls available offering a complete testing package.
- Instrument specific applications available for a wide range of clinical chemistry instruments.
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