Randox Biosciences and Metabolic Syndrome

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Randox Biosciences and Metabolic Syndrome

The Evidence Evolution is a fully automated immune-analyser with random access.  The machine has the capability to process up to 2640 tests per hour with up to 44 analytes screened per biochip. With a wide range test menu Randox can offer the market the service they expect with state-of-the-art intuitive touchscreen software and advanced precision bio-drive robotics.

Metabolic syndrome is described as a combination of diabetes, high blood pressure and obesity. As result of three health conditions going on, it puts the individual at greater risk of developing coronary heart disease, stroke and many other risks. 1 As well as developing additional health conditions it can cause damage to the blood vessels, the blood pressure damages the blood vessels, the obesity causes a lot of strain on the blood vessels and the heart.2 Therefore, can result in serious long-term risks.

Metabolic disease is very common. Studies state that the serious health condition affects about 23% of adults. 3One in four adults in the UK are currently living with metabolic syndrome and often becomes more common with age2.

Usually it affects those who are overweight or considered obese, have an unbalanced diet containing high levels of sugar and fat and have high cholesterol and extremely high blood pressure2 therefore, the condition can be prevented by reducing the risks.

1 According to the NHS, metabolic syndrome occurs when a person has three or more of the following measurements:

  • Abdominal obesity (Waist circumference of greater than 40 inches in men, and greater than 35 inches in women)
  • Triglyceride level of 150 milligrams per deciliter of blood (mg/dL) or greater
  • HDL cholesterol of less than 40 mg/dL in men or less than 50 mg/dL in women
  • Systolic blood pressure (top number) of 130 millimeters of mercury (mm Hg) or greater, or diastolic blood pressure (bottom number) of 85 mm Hg or greater
  • Fasting glucose of 100 mg/dL or greater

There are many ways to prevent metabolic syndrome from developing, making lifestyle changes for example, ensuring their weight is healthy by increasing physical exercise, eating a well-balanced healthy diet containing whole grains, fruit, vegetables and fish and finally, visiting the GP to monitor and manage blood glucose, blood cholesterol and blood pressure, quit smoking and managing your stress.

Randox offers the Evidence Evolution including two Metabolic Syndrome Arrays which allows multiplex testing from a single sample allowing rapid turnaround time and are suitable for both serum and plasma samples.

Metabolic Syndrome Array I

  • Ferritin
  • Interleukin-6 (IL-6)
  • Insulin
  • Leptin
  • Plasminogen Activator Inhibitor-1 (PAI-1)
  • Resistin
  • Tumour Necrosis Factor α (TNFα)

Metabolic Syndrome Array II

  • Adiponectin
  • C-reactive Protein (CRP)
  • Cystatin C

For more information on our Evidence Series or Metabolic Syndrome Range of Assays, contact us at EvidenceSeries@randox.com

 

  1. https://www.nhs.uk/conditions/metabolic-syndrome/
  2. https://www.saga.co.uk/magazine/health-wellbeing/conditions/cardiovascular/metabolic-syndrome
  3. http://www.heart.org/en/health-topics/metabolic-syndrome/about-metabolic-syndrome

 

 


Randox Biosciences and Familial Hypercholesterolemia (FH)

Familial Hypercholesterolemia (FH) is a genetic disorder where the child is born with extremely high cholesterol levels. FH can trace back through several generations.  Cholesterol is vital for the normal function of the human body therefore, it is important to ensure the cholesterol levels don’t get too high because it can result in early onset cardiovascular disease. 1

The FH Foundation states an interesting fact that 1 in 250 people worldwide have FH and over 90% of these people have not been properly diagnosed 2. Majority of these people won’t know they have FH disease until they have a heart attack!

However, there are no clear symptoms if someone has FH until it is too late and the damage has been done. The warning signs include the following:1

  • Swollen tendons/fatty lumps on the knuckles of your hands, at the back of your ankles and knees
  • Cholesterol deposits around the eye-lids (looks like pale and yellowish patches)
  • Gray-white cholesterol deposits around the corneas

A study in 2008 by the British Heart Foundation found that people with FH who are diagnosed and treated before they develop heart disease live as long people who don’t have FH 4. This theory emphasis the importance of getting early diagnosis to prevent long-term problems. Treatment to prevent cardiovascular disease involves taking medication prescribed by the doctor and making lifestyle changes including; modifying diet, increasing exercise, quit smoking, decrease drinking alcohol and ensure the patient gets regular sleep.

Randox offers the Familial Hypercholesterolemia (FH) Arrays I & II to help encourage early diagnosis with rapid turnaround time allowing results to be reported within days compared to NHS waiting lists which can be substantially longer. The two arrays are rapid, simple and accurate which enables the simultaneous detection of 40 FH-causing mutations (20 mutations per array) within the LDLR, ApoB and PCSK9 genes. The mutational status can be determined rapidly from a single test, with a reduced need for confirmatory testing with NGS. The genetic analysis for FH mutations allows for more accurate diagnosis compared to lipid profiling.

Randox can help using the award-winning Biochip Analyser to achieve early and appropriate treatment for those with FH resulting those to adopt a healthier lifestyle and taking cholesterol-lowering medication, risk of heart disease to live a longer and healthy life!

Familial Hypercholesterolemia (FH) Arrays I & II:

  • LDLR – 38 mutations
  • APOB – 1 mutation
  • PCSK9 – 1 mutation

 

To find out more about the products that we offer email us info@randoxbiosciences.com

 

Reference:

https://www.healthline.com/health/familial-hypercholesterolemia#symptoms

https://thefhfoundation.org/about-fh/what-is-fh

 

 


Randox Biosciences: dedicated to advancing scientific discovery

Randox Laboratories is an international clinical diagnostic solutions company with over 35 years’ experience in the industry. Randox is a global market leader, providing revolutionary products for laboratories worldwide and is dedicated to improving health.

Randox Biosciences is part of Randox Laboratories and is dedicated to advancing scientific discovery, drug development and diagnostics. Spanning four key divisions; Life Sciences, Pharma Sciences, Research and Molecular; Randox Biosciences offers complete tailored solutions for clinical and research use.

From initial cultivation of raw materials for assay development, through to providing companion diagnostics, custom and molecular based assays across a range of therapy areas; Randox Biosciences is a trusted partner supplying quality diagnostic solutions to the clinical, life science, pharmaceutical, research and biopharma industries. We specialise in supplying academic centres, genetics laboratories and the global biopharmaceutical industry with products tailored to their specific needs.

Randox Biosciences Research team encompasses a knowledgeable group of who are dedicated to assisting your research project to completion. Recently, the research team has expanded to include Business Development Executives in America to support academic centres of excellence achieve their potential while utilising our quality products. We are proud to welcome Rebecca Newburg who will be focusing her efforts on the US-Midwest market and Celestine Eshiet who will be working on the US -West Coast.

We cover five areas of research such as Sport and Exercise, Cardiovascular, Metabolic, Immunology and Oncology. These five areas include our Metabolic Syndrome Array 1 & 2, Cytokine Arrays and Cardiac Array including CK-MB, H-FABP, Myoglobin and Troponin.

 

If you work in an academic centre and are interested in our variety of arrays, analysers whether that be chemistry or immunoassay analysers, or our reagents or quality control please do not hesitate to contact us at info@randoxbiosciences.com.

 

 

 

 

 

 

 

 


Vivalytic: The all-in-one solution for Molecular Diagnostics

A game-changing partnership between Randox Laboratories and Bosch is changing the accessibility to molecular diagnostics with the launch of a revolutionary product – the innovative platform Vivalytic.

Using Randox-patented Biochip Array Technology, it is the easiest-to-use and most-comprehensive multiplex PCR platform on the market. It provides the broadest range of test options ever seen for an analyser of its size, and also supports single-plex and low-plex testing, simplifying the processes for otherwise-complex laboratory test procedures. Depending on the test application, results will be delivered from 30 minutes.

Biochip Array Technology, developed by Randox Laboratories, is the innovative multiplexing technology which is utilised within the cartridge aspect of the platform. The Biochip allows for the simultaneous detection of multiple analytes from a single sample.

The new platform will be initially released with two molecular arrays available including Respiratory Tract Infection and Sexually Transmitted Infection with other tests to follow.

The Vivalytic is the perfect fit for any laboratory with numerous benefits to enhance your laboratories testing capabilities.

 

Hygienic and space saving

No other peripherals such as laptop, keyboard, barcode scanner or filling stations are required. This makes Vivalytic a hygienic and space-saving all-in-one solution.

 

Direct and clear results

The test result is presented clearly in a summary, but also details on the raw data of each individual measurement can be displayed.

 

Protected system

The Vivalytic integrates the software with the instrument to ensure a safe and reliable run. This is the ultimate protection of the data and the valuable sample material.

 

Networked and combinable

Easy integration with popular standard IT systems makes test results instantly available. An analyser device can be networked and combined with several other devices so that multiple series of tests can be performed simultaneously. All devices are based on the same hardware and software, so that the product family can be expanded quickly and without major development effort.

 

28th European Congress of Clinical Microbiology and Infectious Diseases

Randox Laboratories will be attending the 28th European Congress of Clinical Microbiology and Infections from the 21st – 24th April 2018.

 

Our innovative diagnostic solutions have been developed with consolidation and economy in mind, providing cost savings whilst using pioneering technology.

 

Diagnostics is our passion. We are dedicated to developing solutions that not only meet your needs, but are of the highest quality, the most reliable and the most cost-effective. We look forward to meeting you in Madrid at IFEMA – Feria de Madrid to launch the Vivalytic at our stand 55A.

 

For further information, visit https://goo.gl/S2Yj2c or email info@randoxbiosciences.com

 

 

 


Randox Biosciences: dedicated to advancing scientific discovery

Randox Laboratories is an international clinical diagnostic solutions company with over 35 years’ experience in the industry. Randox is a global market leader, providing revolutionary products for laboratories worldwide and is dedicated to improving health.

Randox Biosciences is part of Randox Laboratories and is dedicated to advancing scientific discovery, drug development and diagnostics. Spanning four key divisions; Life Sciences, Pharma Sciences, Research and Molecular; Randox Biosciences offers complete tailored solutions for clinical and research use.

From initial cultivation of raw materials for assay development, through to providing companion diagnostics, custom and molecular based assays across a range of therapy areas; Randox Biosciences is a trusted partner supplying quality diagnostic solutions to the clinical, life science, pharmaceutical, research and biopharma industries. We specialise in supplying academic centres, genetics laboratories and the global biopharmaceutical industry with products tailored to their specific needs.

Randox Biosciences Research team encompasses a knowledgeable group of who are dedicated to assisting your research project to completion. Recently, the research team has expanded to include Business Development Executives in America to support academic centres of excellence achieve their potential while utilising our quality products. We are proud to welcome Rebecca Newburg who will be focusing her efforts on the US-Midwest market and Celestine Eshiet who will be working on the US -West Coast.

We cover five areas of research such as Sport and Exercise, Cardiovascular, Metabolic, Immunology and Oncology. These five areas include our Metabolic Syndrome Array 1 & 2, Cytokine Arrays and Cardiac Array including CK-MB, H-FABP, Myoglobin and Troponin.

 

If you work in an academic centre and are interested in our variety of arrays, analysers whether that be chemistry or immunoassay analysers, or our reagents or quality control please do not hesitate to contact us at info@randoxbiosciences.com.

 

 

 

 

 

 

 

 


Celebrating Valentine’s Day with the Cardiac Prediction Array from Randox Biosciences

With Valentine’s Day being in the heart of National Heart Month, Randox Biosciences want to take this opportunity to talk about the importance of looking after your heart and the awareness of the tests out there currently on offer.

The British Health Foundation launched National Heart Month with the aim to spread awareness of heart disease and to encourage the nation to make small changes towards a healthier lifestyle.

Currently Coronary Heart Disease (CHD) is the leading cause of death in the UK, with 73,000 people dying from Coronary Heart Disease every year in the UK.1

Coronary Heart Disease is a disease in which plaque builds up inside the coronary arteries. Our arteries supply oxygen-rich blood to the heart muscles, however, over time plaque builds up and can harden. This hardened plaque, then narrows the coronary arteries reducing the flow of oxygen-rich blood to the heart, which can lead to angina or a heart attack to occur.2

CHD is more likely with increasing age, in men rather than in women before menopause and if close relatives have suffered CHD early in life. These risk factors cannot be changed, however, there are other risk factors that can be modified. These are known as elevated blood cholesterol, overweight and obesity, smoking, lack of physical activity, unhealthy diet and stress.

You can prevent and control many CHD risk factors with heart-healthy changes and medication. There is only a few risk factors that can’t be controlled such as your age, gender and family history. Nonetheless, many lifestyle changes help control several CHD risk factors at the same time, such as physical activity which may reduce stress, lower your blood pressure, help control diabetes and help control your weight.

If you believe you are at risk of coronary heart disease, you can ask for a risk assessment for heart diseases, heart attack or stroke. However, current CHD risk assessment tools based on common risk factors such as blood pressure and blood cholesterol levels have low predictive value and take no account of genetic predisposition to CHD.

In recent years, Genome Wide Association Studies (GWAS) have been carried out to identify genetics variants associated with CHD. Meta-analysis of such studies has identified 19 variants as being associated with CHD.

Individually, the presence of an “at risk” variant does not greatly increase the risk of developing CHD. However, the presence of multiple “at risk” alleles can increase the risk of developing CHD two-fold or greater an effect similar to being a current smoker. Combining genotype information with common risk factors could allow individuals to be more accurately classified therefore preventative therapies and lifestyle advice can be targeted to those who require it most.

In order to utilise the GWAS findings within a clinical setting, individuals require to be genotyped for each of the 19 CHD “at risk” SNPs. However, at present this can be a time consuming and expensive process.

Together with key opinion leaders in cardiovascular genetics, Randox has developed the Cardiac Risk Prediction Array which will allow all 19 SNPs to be genotyped simultaneously, which incorporates a test to identify patients predisposed to statin induced myopathy.

Firstly, a multiplex PCR reaction is performed, where the products amplified correspond to the genotype of the patient sample. The PCR products are then hybridised onto the Cardiac Risk Prediction biochip array and imaged using the Evidence Investigator analyser to identify which PCR products are present. Patient samples can be genotyped within 1 day.

This Heart Month, we are urging the pubic to not only help raise awareness of heart disease but also educate themselves on the signs and symptoms to increase early diagnosis. As a global diagnostic company, Randox Biosciences are committed to the ongoing development of diagnostic tests, as well as our research into numerous disease areas to improve health worldwide.

To find out more email us at info@randoxbiosciences.com

 

Sources

1 – HeartUK

2 – National Heart, Lung and Blood Institute

 

 


Focus on Chronic Kidney Disease diagnosis (CKD)

Chronic Kidney Disease (CKD) is a long term condition which involves the progressive loss of kidney function a late diagnosis can result in end stage renal disease requiring kidney dialysis or transplantation. Typically, CKD is result of a combination of other conditions which puts a strain on the kidneys, these conditions can include high blood pressure, diabetes and high cholesterol amongst many other ailments.1

Randox Biosciences are continually researching and developing new tests, targeting various health concerns around the world to improve diagnostics and health worldwide. Recently, our dedicated scientists have developed a new test, utilising our proprietary Biochip Array Technology (BAT) that simultaneously and quantitatively detects multiple early biomarkers associated with kidney damage allowing for earlier intervention and treatment, preventing further kidney damage.

We offer two multiplex Chronic Kidney Arrays as shown below:

Early detection provides those diagnosed with the opportunity to alter their lifestyle in order to improve their kidney and overall health, whether that is through the reduction of salt in their diet, increased physical activity and alcohol limitation.

To find out more about the Chronic Kidney Disease Arrays offered by Biosciences email info@randoxbisociences.com

1 NHS – https://www.nhs.uk/conditions/kidney-disease/

 

 


Randox celebrates British Science Week 2017

Randox celebrates British Science Week 2017

 

Last week was British Science Week 2017, an annual campaign that aims to inspire innovation and celebrate science. To mark the occasion, Randox Laboratories got involved by celebrating the innovation of each Randox product group. The product groups within Randox shared a series of posts, videos and blogs showcasing the #ScienceBehindRandox throughout British Science Week.

Randox

To initiate the Randox British Science Week campaign, Randox shared this video, which highlights the company’s dedication to improving health worldwide. The video provides an introduction about each product group, however throughout British Science Week, each product group has gone into further detail about the #ScienceBehindRandox.

Randox Careers, the RX series, Randox Reagents, Randox Quality Control, Randox Toxicology, Randox Biosciences, Randox Testing Services, & Randox Food Diagnostics all got involved in the British Science Week Campaign. You can read a snippet of each product groups post below, with videos and links to the full content also provided. We hope you enjoy learning about the #ScienceBehindRandox.

Randox – Dedicated to improving health wordwide.

Randox Careers

Joanne Darragh spent some time with Randox Careers to discuss her role as R&D Toxicology Manager.

“Working in this area has been both challenging and exciting as we are at the cutting edge of assay development.  We work in a great team and we work along very closely alongside other departments such as Marketing & Sales so that we are in close contact with what the customer needs, which means we are producing relevant tests very quickly and effectively.  Every day brings a new challenge.”

– Joanne Darragh, R&D Toxicology Manager

Listen to what Joanne had to say on the video above

Randox RX series

As part of British Science Week, the RX series caught up with Daniel Melly, one of our very talented Mechanical Design Engineers based in Randox Teoranta in Dungloe, Ireland.

Daniel was an integral part of the team involved in the design of our new semi-automated analyser, the RX misano. The RX series asked Daniel a few questions about why Randox created this analyser, the design process involved in creating such a unique system, and what his favourite features are.

Randox set out in creating the RX misano with the philosophy of supplying the customer with a more modern, reliable, and aesthetically pleasing analyser than those that are currently available on the market. Robust part selection was always at the fore of any design decisions, and we feel that we have delivered on all of these requirements.” 

– Daniel Melly, Randox Mechanical Design Engineer

Read the full interview the RX series had with Daniel here

The RX misano is currently unavailable to purchase in Germany

Randox Reagents

One unique test by Randox, adiponectin, is becoming an increasingly significant biomarker for health professionals. Low levels have been linked with several illnesses including metabolic syndrome, cancer and cardiovascular disease.

What is adiponectin?

Adiponectin is a protein hormone produced and secreted by fat cells called adipose tissue. Adiponectin is normally found in relatively high concentrations in healthy individuals. Its role in the body is to regulate the metabolism of lipids and glucose, which influences the body’s response to insulin and inflammation.

At Randox, our R&D Scientists are helping to change healthcare. By investing heavily into research and development to develop unique diagnostics tests, such as the adiponectin test, Randox provide doctors with the ability to identify disease risk sooner- offering the opportunity to prevent illness, rather than the need to find a cure.

adiponectin

Read the full Randox Reagents blog entry here

Randox Quality Control

One Simple Change to Randox Quality Control can save your laboratory time and money.

Randox Quality Control are a world leading manufacturer of true third party controls with over 390 analytes covering Antioxidants,  Blood Gas, Cardiac Markers, Routine Chemistry, Coagulation, Haematology, Diabetes, Immunoassay, Immunology, Lipids, POCT, Therapeutic Drugs, Toxicology and Urine Chemistry, providing complete test menu consolidation. Randox Quality Control produces the most consistent material available with the most accurate target values.

Randox Quality Control guarantee to simplify QC practice in any laboratory, just ask one of their 60,000 users worldwide.

Find out more information about Randox Quality Control in the video above

Randox Toxicology

Randox Toxicology provides trusted solutions for the screening for drugs of abuse. With significant reinvestment in Research and Development, we persistently stay ahead of this ever challenging market.  Being the first to develop New Psychoactive Substances tests such as fentanyl, bath salts and flakka allows us to maintain our position as a global leader.

Our pioneering technology has created a number of advancements in the field of toxicology. In particular, our patented Biochip Array Technology which can simultaneously screen from a multi-analyte testing platform, achieving a complete immunoassay profile from the initial screening phase.

Read the full Randox Toxicology blog post here

Randox Biosciences

During British Science Week, we are delighted to introduce you to our latest development utilising this technology; our Gastropanel Array,* a multiplex test engineered to diagnose those at risk of developing peptic ulcers and gastric cancer using non-invasive methods.

Our Gastropanel Array encompasses two quantitative assays, a H. pylori assay  for the detection of antibodies produced in response to a H. pylori infection, a common cause of gastric cancer1 as well as a 3plex Gastropanel assay, for the detection of pepsinogen I (PGI), pepsinogen II (PGII) and gastrin 17 (G17).

Currently recorded as the world’s 5th most common cancer, the majority of gastric cancer cases are diagnosed after presenting as an emergency, when treatment may be less effective due to the cancer being at an advanced stage, highlighting the need for the availability of diagnostics tests like our Gastropanel Array to enable practitioners to administer prompt treatment and ultimately increase survival rates on a global scale.

Read the full Randox Biosciences blog here

Randox Testing Services

Randox Testing Services have shown how they are at the forefront of continually reacting and developing tests for NPS. NPS (formerley known as Legal Highs) have had devastating effects on users since emerging in the UK in 2008. These substances are highly dangerous and have caused unnecessary deaths. This is due to the effects from different elements used in production. Legislation concerning the substances changed in 2016 with the implementation of the Psychoactive Substance Act.

How have Randox Testing Services implemented change? Find out in the video above

Randox Food Diagnostics

Of the 41 antibiotics that are approved for use in food-producing animals by the FDA, 31 are medically important for human health. Randox Food Diagnostics provides advanced screening solutions for 94% of these antibiotics including beta-lactams, quinolones and tetracyclines, allowing you to ensure the integrity of your end product without compromising quality. Randox Food provides multiplex screening solutions validated across a range of matrices including urine, serum, tissue, milk, honey and feed.

The Evidence Investigator matched with Biochip Array Technology (BAT) provide the end user with fast, reliable results to aid in ensuring your produce is antibiotic free. BAT provides a platform for the simultaneous determination of multiple drug residues from a single sample using miniaturised immunoassays with implications in the reduction of sample/reagent consumption and an increase in the output of test results. 

To read Randox Food Diagnostics full blog click here

We hope you enjoyed our informative British Science Week content from each of our Product Groups.

Look out for our Quiz later this week to test your knowledge on the #ScienceBehindRandox

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We Are Randox | Randox employees give back to the community with charity events and fundraising initiatives

With the January blues in full force we decided to have a look back over all the wonderful events that Randox staff took part in during 2016. Together Randox staff rallied together to raise money for numerous events and charities making a huge difference to the lives of others.

Back in April Rachel Walls, our technical support specialist in Ardmore initiated a bake sale on behalf of her sister, Ursula McKenna who ran both the Dublin Marathon and Manchester half Marathon in aid of Cystic Fibrosis Trust. The bake sale was a roaring success and Randox staff enjoyed a selection of scrumptious buns raising a total of £308 that went towards Ursula’s total fundraising amount of £3000.

Ursula said,

“Our cousin suffers from Cystic Fibrosis, and running a few marathons is easy compared to what he has to deal with on a daily basis.”

Cystic Fibrosis is a genetic condition caused by a faulty gene that controls the movement of salt and water across the cell wall. This causes mucus to build up in the lungs and digestive tract, causing problems with breathing and digestion. An estimated 1 in 2,500 babies born in the UK have Cystic Fibrosis, with more than 2.5 million people in the UK carrying the faulty gene.  Currently there is no cure for Cystic Fibrosis, however there are treatments to help manage the symptoms. The Cystic Fibrosis Trust helps suffers by funding cutting-edge research, driving up standards of care and supporting people with the condition and their loved ones every step of the way.

May was the month that Randox staff and the Randox Biosciences department joined together to help raise awareness of stroke by wearing purple clothes to work.

Stoke is a brain attack that occurs when the blood supply to part of the brain is cut off. Blood carries essential nutrients and oxygen to the brain so without blood your brain cells can be damaged or die.

This damage can have different effects, depending on where it happens in your brain. A stroke can affect the way your body works as well as how you think, feel and communicate. The Stroke Association have dedicated the month of May to raising awareness and increasing the public’s knowledge of this condition.

In July Gary Laverty, one of our software developers who works in our Laurelbank site  took a beating when he allowed Randox staff to throw water balloons at him in order to raise money for Macmillan Cancer Support. This charity aims to improve the lives of everyone who is diagnosed with cancer. Their aim is to make life a little brighter and ensure that no one faces this horrible disease alone. They are on hand to offer assistance right from the beginning of a diagnosis, through treatment and beyond, including support to the wider family circle.

Gary raised a total of £409.38 on the day which was presented to Margaret Young from Macmillan Cancer Support at Randox headquarters in Crumlin.

Gary Laverty said,

“When my father was ill last year, Macmillan offered tremendous support to both him and my family. Their commitment to helping cancer patients is incredible, really life-changing. I debated a few fundraising ideas but thought that the water balloon idea was something unusual so I hoped people would see it as a really fun event. The fundraiser went really well and I am delighted at the amount we raised for such an amazing charity! My colleagues got really involved and it was a really fun event, thankfully it wasn’t too cold on the day!”

In the months leading up to Christmas Randox Teoranta in Dungloe our team of scientists engineers and software developers organised a Christmas shoebox appeal in conjunction with Team Hope, a charity based in Ireland, who for the past 18 years have delivered Christmas shoebox gifts to over three million children in some of the remotest and poorest parts of the world. Randox Teoranta  filled a total of 54 boxes with items ranging from school essentials, clothes, hats, scarves gloves and socks and of course extra special gifts for Christmas including games toys, sweets and even musical instruments.

Claire Newbon, Manufacturing Operative said,

“Within the team here at Randox Teoranta we are all very fortunate to have great jobs, loving families and a roof over our heads.  But we are very aware that there are adults and children in other parts of the world who aren’t so lucky, through no fault of their own.

“At the most joyful time of the year, the Teoranta team wanted to be able to share the magic of Christmas with those children who would otherwise not get any presents.”

In the week leading up to Christmas Randox staff organised a Christmas jumper day with donations going towards Save the Children and a Christmas raffle on behalf of Hope 365.  £640.25 was raised for Save the Children, and £4464.00 was raised for Hope 365, which would go towards furnishing “Hope Homes” in Ethiopia so that the children will have somewhere peaceful to sleep at night.

The Christmas raffle took place on 23rd December during which all staff from each site came together to see if they were lucky enough to win any of the prizes that were on offer. Prizes included a 55inch TV, M&S and Amazon vouchers, Christmas hampers, an IPad Air 2 and an extra day’s annual leave.

Randox Teoranta in Donegal also held their own Christmas Raffle and Coffee Morning with all proceeds going towards the local hospital in Dungloe. A total of  €740 was raised for the hospital which was greatly appreciated.

Thank you for your generous donations throughout the year, we hope that we can continue to support charities and events throughout 2017.

If you would like to further support Hope 365  they are actively seeking 52 people to take part in a marathon or part of a marathon this year, to compliment a person who is running 52 marathons in one year for the charity. There is also a football academy, endorsed by Paddy McNair, which is taking place in July in Ethopia if you would like to get involved with this. For further information, please contact Internal Communications.

If you would like to get involved with charity fundraising in 2017, please share your ideas with us by emailing internal.communications@randox.com.  


Randox supports calls from Oxford University for more accurate diagnosis of diabetes following report warning

Calls for more accurate diagnosis of people at risk of developing Type-2 diabetes have been supported by Randox, following a warning raised by an Oxford University study which looked into efforts to tackle the worsening epidemic of the condition.

The study, which was published in the British Medical Journal, examined results from the NHS’s programme which involves a screening test for pre-diabetes. The authors determined that the UK’s National Diabetes Prevention Programme is unlikely to have much impact because the blood tests used were inaccurate at detecting pre-diabetes, though these are currently the only ones available to doctors and patients. The study argues that if the screening is inaccurate then people will either be falsely reassured or receive incorrect diagnoses, which will not help the worldwide challenge to reduce people at risk of developing diabetes that continues to increase across the world.

It is estimated that Type-2 diabetes causes 22,000 early deaths every year in England alone. Across the UK over 3m people currently have the condition though experts say this will increase to 5m by 2025.

With current treatment taking up almost 9% of the annual NHS budget – roughly £8.8bn a year – the implications for future healthcare budgets are clear if this dangerous trend persists.

Global reagents Manger Susan Hammond said,

Although we wholly back the NHS’s belief that positive lifestyle changes make crucial differences in people’s health and lives, we also believe that unless earlier and more accurate diagnostic screening is employed on a twin-track of treatment, this epidemic will continue to worsen.  We welcome that this study highlights the fact that clinician’s s are currently limited in what they can use to tackle the threat posed by diabetes. There are emerging biomarkers   they could be given access to,  such as Adiponectin and determining a person’s risk of Metabolic Syndrome.”

Assessing Adiponectin levels allows doctors to calculate the amount of visceral fat stored around a patient’s organs. This deep fat, which is not visible to the naked eye, is linked to health problems including Type-2 diabetes. High levels of adiponectin equate to low levels of visceral fat which can be combated by improving your diet, exercise habits and even stress levels. Given that 70% of Type-2 diabetes can be prevented by lifestyle changes, there is strong correlation that by detecting low levels of Adiponectin and taking corrective and preventive action, it could results in a decrease in the numbers of people who develop the life altering condition.

In addition to a test for the Adiponectin biomarker, Randox Biosciences have created a Metabolic Syndrome Array that measures 12 markers associated with metabolic syndrome and cardiovascular disease. Metabolic Syndrome is a is a group of cardiovascular risk factors that affects over 20% of adults and  results in a person being three times more likely to have a stroke or heart attack, and five times more likely to develop diabetes.

Mrs Hammond concluded,

“We would ultimately like to see all medical professionals who are at the forefront of patient care armed with the most accurate diagnostic tools available. Updating traditional practice may not be easy but we believe it is imperative to do so, if we are to effectively challenge this global epidemic.”

Randox remains focused on providing early diagnoses and preventing illnesses by providing innovative diagnostics tests that will continue to revolutionise the healthcare landscape.

To find out more about our tests for metabolic arrays click here and Adiponectin click here.


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