Randox Biosciences and Metabolic Syndrome

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Randox Biosciences and Metabolic Syndrome

The Evidence Evolution is a fully automated immune-analyser with random access.  The machine has the capability to process up to 2640 tests per hour with up to 44 analytes screened per biochip. With a wide range test menu Randox can offer the market the service they expect with state-of-the-art intuitive touchscreen software and advanced precision bio-drive robotics.

Metabolic syndrome is described as a combination of diabetes, high blood pressure and obesity. As result of three health conditions going on, it puts the individual at greater risk of developing coronary heart disease, stroke and many other risks. 1 As well as developing additional health conditions it can cause damage to the blood vessels, the blood pressure damages the blood vessels, the obesity causes a lot of strain on the blood vessels and the heart.2 Therefore, can result in serious long-term risks.

Metabolic disease is very common. Studies state that the serious health condition affects about 23% of adults. 3One in four adults in the UK are currently living with metabolic syndrome and often becomes more common with age2.

Usually it affects those who are overweight or considered obese, have an unbalanced diet containing high levels of sugar and fat and have high cholesterol and extremely high blood pressure2 therefore, the condition can be prevented by reducing the risks.

1 According to the NHS, metabolic syndrome occurs when a person has three or more of the following measurements:

  • Abdominal obesity (Waist circumference of greater than 40 inches in men, and greater than 35 inches in women)
  • Triglyceride level of 150 milligrams per deciliter of blood (mg/dL) or greater
  • HDL cholesterol of less than 40 mg/dL in men or less than 50 mg/dL in women
  • Systolic blood pressure (top number) of 130 millimeters of mercury (mm Hg) or greater, or diastolic blood pressure (bottom number) of 85 mm Hg or greater
  • Fasting glucose of 100 mg/dL or greater

There are many ways to prevent metabolic syndrome from developing, making lifestyle changes for example, ensuring their weight is healthy by increasing physical exercise, eating a well-balanced healthy diet containing whole grains, fruit, vegetables and fish and finally, visiting the GP to monitor and manage blood glucose, blood cholesterol and blood pressure, quit smoking and managing your stress.

Randox offers the Evidence Evolution including two Metabolic Syndrome Arrays which allows multiplex testing from a single sample allowing rapid turnaround time and are suitable for both serum and plasma samples.

Metabolic Syndrome Array I

  • Ferritin
  • Interleukin-6 (IL-6)
  • Insulin
  • Leptin
  • Plasminogen Activator Inhibitor-1 (PAI-1)
  • Resistin
  • Tumour Necrosis Factor α (TNFα)

Metabolic Syndrome Array II

  • Adiponectin
  • C-reactive Protein (CRP)
  • Cystatin C

For more information on our Evidence Series or Metabolic Syndrome Range of Assays, contact us at EvidenceSeries@randox.com

 

  1. https://www.nhs.uk/conditions/metabolic-syndrome/
  2. https://www.saga.co.uk/magazine/health-wellbeing/conditions/cardiovascular/metabolic-syndrome
  3. http://www.heart.org/en/health-topics/metabolic-syndrome/about-metabolic-syndrome

 

 


Speciality Control Calibrators

Therapeutic Drug Quality Control

Adhesion Molecules Calibrator Series

Calibrator for use with the Randox Adhesion Molecules Array.

DescriptionSizeAnalytesCat No
Adhesion Molecules Calibrator Series9 x 1ml5EV3568

Analytes

  • Vascular cell adhesion molecule-I (VCAM-I)
  • Intercellular adhesion molecule-I (ICAM-I)
  • E-Selectin (E-SEL)
  • P-Selectin (P-SEL)
  • L-Selectin (L-SEL)

Cytokine Array Calibrator Series

Multi-analyte calibrator covering 12 different cytokines.

DescriptionSizeAnalytesCat No
Cytokine Array Calibrator Series9 x 1ml12EV3561

Analytes

  • Interleukin – 1α (IL-1α)
  • Interleukin – 1β(IL-1β)
  • Interleukin – 2 (IL2)
  • Interleukin – 4 (IL4)
  • Interleukin – 6 (IL6)
  • Interleukin – 8 (IL8)
  • Interleukin – 10 (IL10)
  • Vascular Endothelial Growth Factor (VEGF)
  • Interferon Υ(IFNΥ)
  • Tumour Necrosis Factor a (TNFa)
  • Monocyte Chemoattractant Protein-1 (MCP-1)
  • Epidermal Growth Factor (EGF)

 

Endocrine Array Calibrator Series

Multi-analyte calibrator covering 4 analytes.

DescriptionSizeAnalytesCat No
Endocrine Array Calibrator Series9 x 1ml4EV3712

Analytes

  • Cortisol
  • DHEA-Sulphate
  • 17aHydroxyprogesterone
  • Leptin

Synthetic Steroids Calibrator

Multi-analyte calibrator for 5 different synthetic steroids.

DescriptionSizeAnalytesCat No
Synthetic Steroids Calibrator9 x 1ml5EV3708

Analytes

  • 17β Clostebol
  • Ethinylestradiol
  • Gestagens (generic)
  • Methyltestosterone
  • Methandriol

Metabolic Syndrome Array I Calibrator

Multi-analyte calibrator covering 9 parameters associated with metabolic syndrome.

DescriptionSizeAnalytesCat No
Metabolic Syndrome Array I Calibrator9 x 1ml9EV3756

Analytes

  • C-Peptide
  • Ferritin
  • Interleukin-6 (1L6)
  • Resistin
  • Insulin
  • Interleukin-1a(1L-1a)
  • Tumour Necrosis Factor a(TNFa)
  • Leptin
  • Plasminogen Activator Inhibitor-1

Thyroid Total Calibrator Series

Multi-analyte calibrator designed for use in calibration of the Randox Thyroid Total Array.

DescriptionSizeAnalytesCat No
Thyroid Total Calibrator Series9 x 1ml3EV3555

Analytes

  • TSH
  • T4
  • T3

Thyroid Free Calibrator Series

Multi-analyte calibrator designed for use in the calibration of the Randox Thyroid Free Array.

DescriptionSizeAnalytesCat No
Thyroid Free Calibrator Series9 x 1ml3EV3563

Analytes

  • TSH
  • FT3
  • FT4

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