Evidence Investigator: One Analyser for Multiple Food Testing Industries
The Randox Evidence Investigator: One Analyser for Multiple Food Diagnostic Industries
The Randox Evidence Investigator has been validated for Randox Food Diagnostics across various food matrices including tissue, feed and cereals, honey, aquaculture, and milk, making it the perfect testing equipment solution for any food testing laboratory.
How can the Randox Evidence Investigator benefit me?
- The Randox Evidence Investigator is a multi-analyte quantitative drug residue screening analyser. Using Randox’s patented Biochip Technology, the analyser ensures screening food for drug residues is accurate and efficient, offering a range of laboratories comparable results to LC-MS/MS.
- Using multiplex technology, the Evidence Investigator can provide simultaneous detection for a wide range of analytes from a single sample, saving you time and resource, and getting the reliable results you need.
- The analyser uses unique image processing software to translate the Relative Light Units (RLU) generated from the chemiluminescent reactions into an analyte concentration.
- No manipulation of results is required, which reduces the scope for any operator error. The Randox Evidence Investigator provides excellent sensitivity with a quantitative concentration result (ppb) for each analyte tested.
- The analyser boasts an extensive test menu with tests for the most widely used drug residues and the most commonly detected mycotoxins in the feed production industry.
- When purchasing the Randox Evidence Investigator, you will receive the complete package required for sample analysis which includes the analyser, PC and imaging software, a thermoshaker and a barcode scanner.
Visit the Randox Food Diagnostics website for more information on this technology.
For all enquiries relating to food testing on any of our Randox analysers, please contact us via email at: email@example.com
Want to know more?
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Meat & Seafood
Preparing your vineyard for harvest: Excellence in every glass
Each year from August through October and maybe a little later, the Northern Hemisphere comes alive with the excitement and rush of harvest as wine makers celebrate with festivals, dinners and get together as the yearlong grape growing season comes to an end and harvest begins.
Producing the highest quality wine grapes is dependent upon many factors – mainly the right amount of sun and rain. The growing process can be stressful for winemakers as they anxiously keep a close eye on weather conditions, in hope that it’s clear of frosts, heatwaves and hail. These can all have detrimental impacts on the vineyard.
However, this year it hasn’t been weather conditions that have been a worry for winemakers. Instead, many vineyards have been significantly impacted by the ongoing COVID-19 pandemic and events that once brought life to local communities and vineyards are now taking place online. Channels for selling wine such as hotels, restaurants and airports have dried up with current restrictions, and online and supermarket sales have never been more important.
Like many industries the food and beverage sector has continued to operate through one of the most challenging times. Using a combination of expert knowledge and technology has ensured that the expectation put upon winemakers to create excellent wine is regularly achieved even in the toughest conditions.
Did you know that a wide range of elements are measured to ensure perfection in every bottle, including levels of acidity and sugar ripeness relevant to the desired style of wine? Technology has been giving winemakers a helping hand in ensuring the quality of each harvest for many years including Randox Food‘s RX misano – a compact, fast and efficient benchtop spectrophotometer capable of gaining results in 8-15 minutes.
Want to know more?
Contact us or visit our Randox Food Diagnostics website.
Meat & Seafood
Ergot Alkaloid ELISA now available from Randox Food Diagnostics
Available now, the Randox Food Diagnostics Ergot Alkaloid ELISA (Catalogue Number EA3491) is:
Compliant with the lowest proposed maximum levels being considered by the European Commission for the total of 12 main ergot alkaloids applicable from July 2020, including the stricter drafted limits from July 2022, for cereal-based feed, wheat and rye milling products.
Accurately detects the sum of 12 main ergot alkaloids to test the most affected type of cereal – rye flour. Randox’s ELISA results show an excellent 95% correlation with the assigned concentration within FAPAS Proficiency Test scheme.
Unrivalled in the detection of low contamination levels. The Z-score of FAPAS PT of -0.6 for baby multigrain food was obtained using Randox Ergot Alkaloids ELISA.
Validated based on Commission Regulation (EC) No 519/2014 as a semi-quantitative screening method for cereal-based feed, wheat and rye milling products. The same regulation was followed for fit-for-purpose approach assessment for confirmatory method, which approves Randox Ergot Alkaloids ELISA as being a method for official control. It is successfully assessed by fit-for-purpose approach according to Commission Regulation (EC) No 401/2006 as approved method of analysis.
Evaluated by third-party laboratory (Wageningen Food Safety research / WFSR, 2019) and proved to be able to distinguish between negative and positive samples. Randox’s ELISA displayed no false-negatives and no false-positives in this study. Across all commercially available ELISA tests, Randox Food Diagnostics Ergot Alkaloids ELISA was the only test which showed good performance with all 3 sample types, including 11 matrices and a total of 24 samples.
Reference reports are available upon request.
For more information visit https://www.randoxfood.com/feed-and-cereals-analysis/ergot-alkaloids/ or email us directly at firstname.lastname@example.org
Want to know more?
Contact us or visit our Randox Food Diagnostics website.
Meat & Seafood
Randox in Top 10 Food and Beverage Technology Providers in Europe 2019
Randox Food Diagnostics have been selected as one of the Top 10 Food and Beverage Technology solution providers in Europe for 2019.
The news was announced in an article in the Food and Beverage Technology Review magazine, which highlighted companies at the forefront of technological developments in the food and beverage industry.
The magazine’s editorial board assessed and shortlisted some of the most prominent organisations in the industry that solve challenges by implementing the current technological trends in the space, and nominated Randox in the top 10 in an article entitled; “Randox: Bringing Diagnostics to the Food Industry.”
The article highlights the history of Randox, which was established by our Managing Director Dr Peter FitzGerald in 1982. We traditionally focused on placing our diagnostics technologies in the likes of hospitals, laboratories and veterinary clinics, however in recent years have utilised our expertise in diagnostic technology to diversify into another key area of healthcare – food safety.
Our Randox Food Diagnostics division offers the latest and most comprehensive diagnostic technologies to food producers across a range of industries including meat, seafood, dairy, honey and cereals, to ensure food safety and satisfy customer demand.
Our patented Randox Biochip Array Technology can provide screening of up to 54 food samples providing results for drug residues and toxins within 3 hours, saving both time and money for clients. The Randox Biochip facilitates simultaneous detection of multiple drug residues or pathogens including antibiotic, anti-parasitic, anti-inflammatory, growth promoter, and mycotoxin diagnostics.
“With faster, simpler and more efficient testing, Randox Biochip increases efficiency within producer processes and, within the market place, increases consumer confidence, a reason why leading food producers, as well as hospitals, laboratories, toxicology centres, and health clinics, utilise Randox products,” says Dr Peter FitzGerald.
Most recently we unveiled the Randox Infiniplex; a biochip for milk testing which allows milk testing laboratories to carry out multiple tests simultaneously on a single milk sample.
“Our Infiniplex array greatly differs from other milk residue tests as it uses multiplexing technology that reduces our customers’ testing time to four hours and requires a small sample volume (25μl),” says Kerrie McAuley, VP of Marketing, Randox Food Diagnostics.
Randox Food is also working on pesticides arrays for milk and honey, and additionally a Bovine Pathogen Array to branch out into animal health and wellbeing screening in milk for viruses such as bovine diarrhoea.
Want to know more?
Contact us or visit our Randox Food Diagnostics website.
Meat & Seafood
Randox Food Diagnostics will be attending Apimondia 2019 in Montreal, Canada from the 8th – 12th September.
Apimondia is the International Federation of Beekeepers’ Association. Its major objective is to facilitate the exchange of information and discussions within the honey industry by organising seminars where beekeepers, scientists, honey-traders, agents for development, technicians and legislators meet to listen, discuss and learn from one another.
In order to help the honey industry Randox Food Diagnostics have developed Biochip Array Technology. Biochip allows for the detection of multiple antibiotics / antimicrobials / pesticides from a single honey sample.
Antibiotics such as oxytetracycline are essential for the control of bacterial diseases of agricultural plants. Most applications are by spray treatments in orchards therefore bees collecting nectar from treated plants causes antibiotic residues to transfer to the honey.
It has previously been idenitified that antibiotic-resistant bacteria can be found in the guts of insects feeding on a variety of plants, which are not exposed to significant levels of antibiotics in other forms. K Ignasiak 2016 Insects are responsible for the pollination of most flowering plants. Importantly, insects have an economic role, as domesticated pollinators bees alone contribute between $1.6 and $5.7 billion to US agriculture alone. This exposure to antibiotic residues can cause adverse health effects in humans via honey consumption and in the long term create antibiotic resistance within the entire food chain.
Randox offer a vast number of arrays for the detection of antimicrobials in honey including: sulphonamides, trimethoprim, dapsone, Quinolones, streptomycin, tetracyclines, erythromycin, nitroimidazoles and many more. Our Biochip platform enables the user to run up to 54 honey samples on the Evidence Investigator analyser in under 2 hours 30 minutes, allowing the user to consolidate costs and time.
See our full range of arrays for the detection of antibiotics on Biochip Array Technology:
Stop by booth B1 at Apimondia to find out about the Randox Food Diagnostics range of products for the screening of antibiotics in honey.
For further information please email email@example.com
Acetic Acid in winemaking
When it comes to winemaking, the acidity in wine is an important component for the quality and taste. It adds a sharpness to the flavours and is detected most readily by a prickling sensation on the sides of the tongue and a mouth-watering aftertaste.
Acetic acid is a two-carbon organic acid produced in wine during or after the fermentation period. It is the most volatile of the primary acids associated with wine and is responsible for the sour taste of vinegar.
During fermentation, activity by yeast cells naturally produces a small amount of acetic acid. If the wine is exposed to oxygen, Acetobacter bacteria will convert the ethanol into acetic acid. This process is known as the “acetification” of wine and is the primary process behind wine degradation into vinegar.
|RX misano||0.117 g/l||Conc. Of standard|
|RX Monaco||0.03 g/l||Conc. Of standard|
For more information about our food testing for winemaking please contact us at: firstname.lastname@example.org
The NHS are rolling out electronic prescribing in the fight against antibiotic resistance.
A recent article in the Telegraph newspaper reports that;
“Health chiefs have drawn up the plans amid warnings that antibiotic resistance now poses as great a threat as climate change.”
Matt Hancock, the Secretary of State for Health and Social Care UK will be informing attendees of the World Economic Forum in Davos that “we are on the cusp of a world where a simple graze could be deadly”. He has stated that it needs to be treated as a “global health emergency” and wants to cut the use of drugs across the country by 15% by setting targets.
The head of the NHS Mr Simon Stevens, said that; “much of the change would be achieved by the rollout electronic prescribing across the health service.” This would allow health officials to detect areas that are prescribing the most antibiotics so that they can try and persuade medics to cut down.
Prime Minister Theresa May said: “The increase in antibiotic resistance is a threat we cannot afford to ignore.
“Government data shows that, since 2014, the UK has cut the amount of antibiotics it uses by more than 7 per cent and sales of antibiotics for use in food-producing animals has dropped by 40 per cent.”
“The amount of antimicrobials used in food production internationally is at least the same as that in humans, and in some places is higher. For example, in the US more than 70% of antibiotics that are medically important for humans are used in animals.
“When properly used, antibiotics are essential for treating infections in animals, but excessive and inappropriate use of the drugs is a problem.
A considerable amount of antibiotics are used in healthy animals to prevent infection or speed up their growth. This is particularly the case in intensive farming, where animals are kept in confined conditions.”
Randox Food Diagnostics have developed Biochip Array Technology a multiplexing platform which allows the screening of up to 54 food/feed samples for a large range of antibiotics in under 3 hours on the Randox Evidence Investigator analyser.
To find out more information on how Biochip Array Technology works visit our website at: www.randoxfood.com
Or contact us directly at: email@example.com
Randox Food Diagnostics recently reported that the European Parliament has banned the use of antibiotics that are important for human medicine use on animals, and is prohibiting any antimicrobials in livestock without a vet prescription. The new legislation, that is to become law by 2022, states that antimicrobials cannot be used to improve performance or compensate for poor animal conditions.
The European Medicines Agency (EMA) have now documented a significant drop in overall veterinary antibiotic sales across Europe. The EMA recognise that the reduction highlights the efforts made by the European Union (EU) and various stakeholders, promoting prudent use of antibiotics in the animal sector and its positive impact. The reduction of antibiotic use in food-producing animals is a key pillar to the EUs One Health Action Plan against Antimicrobial Resistance (AMR), according to a report conducted by the University of Minnesota.
30 countries in total submitted data between 2011 and 2016. German antibiotic sales dropped by 58%. However, whilst the majority of countries saw a drop in sales, six countries reported an increase of more than 5%. Germany’s implementation of an antibiotic minimising programme has helped the country to minimise antibiotic use, by requiring farmers raising cattle, pigs, chickens, or turkeys to report the frequency of antibiotic treatment on their farm every 6 months. If animal treatment frequency is above the median of all farms, operators must evaluate their usage with a veterinarian.
This major step forward in public health has a direct impact on the environment and food. Randox Food Diagnostics recognise the importance of improving the global food safety chain, and continue to transform the landscape by developing high quality revolutionary screening products. Our reliable and economic testing methods enable the user to detect multiple drug and toxin residues from a single sample, including antimicrobials, growth promoting compounds, synthetic steroids, anthelmintics and coccidiostats. With an expanding range of 37 ELISAs, 21 multiplex screening arrays and 20 enzymatic/colourmetric reagents, our trusted solutions ensure that better science means safer food.
For any questions, email us directly at: firstname.lastname@example.org
With just one month to go until IDF WDS 2018 in Daejeon, South Korea preparations are underway at Randox Food Diagnostics HQ. IDF WDS is the world’s leading dairy conference, attended by industry experts, multi-national dairy processors, standing committees and academics, the event is truly one of a kind. Randox Food Diagnostics are exhibiting at booth #16 showcasing our most innovative development yet, the InfiniPlex for Milk Array.
InfiniPlex for Milk is a dairy test kit that offers testing using the most innovative method on the market. Testing milk at various points of the production process is an essential part of the quality control process. Contaminants are administered to dairy cattle to improve herd health, stop the spread of disease and deliver a high-quality product. As a result of this it then becomes essential to screen the milk to ensure no residues pass through to the final product.
The quality of milk is gaining closer inspection on a global scale with antimicrobial resistance at the forefront of concerns. Regulations are getting stricter and many processors are facing the problem that their current quality control method does not have a comprehensive enough test menu. The InfiniPlex for Milk Array helps processors tackle this problem by providing a test menu that complies with EU regulated antibiotics from one sample of raw milk.
There are two analysers that can run the InfiniPlex test kit, the Evidence Investigator and the Evidence MultiSTAT. The Investigator is suitable for laboratories with high throughput delivering 48 samples in under 2 hours and the MultiSTAT is perfect for onsite testing at dairy processors, border control or at farm level with results available in under 20 minutes.
Join us at IDF 2018, Daejeon, South Korea to learn more about how InfiniPlex for Milk can fit in with your quality control process. Alternatively, contact email@example.com for more information.
The potential presence of drug residue contaminants in food products destined for human consumption is an increasingly popular topic of conversation in the industry but what are the main challenges facing the industry to tackle this potential issue?
Drug residue contaminants in food products is a discussion that involves the global community but each individual country or trade bloc has their own protocols and regulations relating to the control and monitoring of residues. The different legislations are designed to protect the general public as well as the food industry interests in their individual countries. Any business that wishes to sell their products within other countries or regions must meet their legislative requirements relating to drug residues. These differences in regulations have increased the need for increased dialogue on the issue as well as the implementation of effective monitoring systems.
The industry must deal with the potential of residues from antibiotics and growth promoting hormones entering the food chain. This will involve ensuring correct dosage per animal and also adhering to withdrawal periods set for their region. The second issue the industry faces is the stigma received from the misuse of these antibiotics and growth promoting hormones.
While there is a potential for misuse it should always be noted that a producer’s main concern should always be animal health, which leads to a quality end product. The use of antibiotics is to ensure the health of the animal and to reduce the potential knock on effect of untreated diseases which could create a downturn on yield. Growth promoting hormones are used to increase this yield also but should never be done so at the expense of a safe end product.
Residues from particular drugs in food produce can have serious implications for human health. As such many countries have set Maximum Residue Limits (MRLs) or tolerances for these residues in food. The Maximum Residue Limit is the maximum concentration of a residue that can be present in a product from an animal or animal by product intended for the food supply. These MRLs mean that it is required by law in the enforcing countries that any product in the food chain cannot contain residue levels that are harmful to human health above these limits.
There has been controversy over measures to tackle drug residues in foods as there are no internationally accepted standards for many drugs. Ractopamine in particular has caused trade disputes as it is permitted in food production in some countries like the US & Canada, but the European Union, China, Taiwan and over 100 other countries have banned its use.
The real challenge the food industry faces is ensuring their testing methods are effective and reliable to ensure the safety of a variety of end products. To name a few of these diverse products we can look at the dairy, meat, seafood, feed and honey markets.
The dairy industry is under constant scrutiny and pressure to constantly produce high volumes of milk whilst maintaining a superior standard of quality in their dairy products. As part of the production process various contaminants are administered to cattle in an effort to systematically treat various infectious diseases and maintain a healthy herd. A direct consequence of this is the requirement of routine monitoring and testing within farms and dairy processors to ensure that the levels of contaminants in milk are within legal regulations not exceeding Maximum Residue Limits and that unauthorised substances are not found at any level in milk.
Testing can be conducted at several points during the production process. Firstly, farm level testing can be carried out to screen milk from cows that have been separated from the herd and undergone antibiotic treatment. Secondly, the dairy processor is required to conduct testing both onsite taking samples from tankers and retrospective testing as a method of internal surveillance to ensure the milk supplied from several farms is within global regulatory limits. Thirdly, retailers can test the processed milk end product to guarantee the milk is antibiotic free before it’s added to supermarket shelves for consumers.
Global meat production and consumption have increased rapidly in recent decades. Worldwide meat production has tripled over the last four decades and increased 20 percent in just the last 10 years. Meanwhile, industrial countries are consuming growing amounts of meat, nearly double the quantity in developing countries. Mass quantities of antibiotics are used on livestock to reduce the impact of disease, contributing to antibiotic resistance in animals and humans alike. Worldwide, 80 percent of all antibiotics sold in 2009 were used on livestock and poultry, compared to only 20 percent used for human illnesses.
Growth promoters, which are tested for under the NRCP, are hormonal and antibiotic substances that may be used in food producing animals for growth promotion in livestock animals thus increasing the production of muscle meat and the reduction of fat. The type of growth promoter used is dependent on the animal species and mode of rearing with steroid growth promoters used for beef cattle and antibiotic growth promoters, which are usually added to feedstuffs, such as the coccidiostats used in the poultry industry and chlortetracycline used in the porcine industry. The rapid speed of meat production calls for the need to test for drug residues frequently to prevent them from ending up in the food chain.
The global aquaculture industry has grown steadily over the past five decades, increasing at an average rate of 3.2%. However, this growth has come at a cost, with the industry facing many new challenges. Farmed seafood is often treated with medicated feeds which contain antibiotics such as leucomalachite green and nitrofurans for example to prevent from disease spreading, they are also exposed to other harmful residues used to treat algae etc. within the ‘pens’ where they are kept.
The FAO (2012) reported that 38% of fish produced globally is exported, highlighting the imbalances in regional supply and the changing tastes of the global consumer. This increased level of exporting and importing shows the importance of drug residue screening within the global aquaculture industry. This increased level of exporting and importing shows the importance of drug residue screening within the global aquaculture industry.
The global animal feed processing market is estimated at US$21.61 billion in 2018 and is projected to reach US$ 26.62 Billion by 2023. The market is driven by factors such as the rising awareness of feed nutrition and health, technological advancements in the equipment industry and increase in the demand for feed around the world. Medicated feeds containing veterinary are often used to help prevent disease within livestock and there are MRLs for feed which has created the need for testing as high levels of residues can have an effect on livestock health and also transfer through to meat products for human consumption. With humidity levels rising in recent years there has been an influx in the level of mycotoxins found within feed and cereals. These toxins are fungal and can affect both livestock and human health for example mycotoxicoses which is a disease which can affect the respiratory system. The main cause of mycotoxins within stored grains are when the grain is damp or cracked and kept in insufficient storage conditions. These factors have made it necessary for feed and cereals to be tested for both drug residues and mycotoxins to ensure that they do not end up within the food chain.
The global honey market is growing at a rapid pace and the global consumption of honey is to reach 2.5 million tones by 2022. This growth is driven for consumers demand for natural and healthy alternatives to artificial sweeteners over cane sugar. There is also a growing awareness of the health and healing benefits of honey which is driving the demand for the use of honey for medicinal use, manuka honey sales continue to grow for its antibacterial and anti-inflammatory properties. The rapid rise in demand for honey outweighs the amount that can be produced in a natural form globally due to a decline in the number of bees. This has influenced the quality of honey being produced as some producers take to diluting natural honey with high-fructose corn syrups in order to supply the demand. There is a requirement for keepers to treat bee colonies with antibiotics to prevent CCD and other diseases such as varroa mites and there is a chance that these harmful drug residues can be transferred through to the end product ‘natural’ honey. The use of antibiotic drugs in apiculture is globally restricted and there are no MRLs set for antibiotics in honey as it a natural product and needs to be antibiotic free, this has cause the need for testing both for drug residues and the overall quality of the honey being produced.
Due to the requirement to use a variety of drug treatments in the food industry and also the potential economic benefits to be gained from the use of growth promoters, there will continue to be use in animal production. However, as analytical methods of detection become more sensitive, producers are given further options for testing.
The surveillance for the potential presence of these residues of veterinary substances is regulated by the EU Directive 86/469/EEC. This directive outlines the guidelines for sampling and testing within a residue monitoring programme.
The requirement to meet these standard and the MRLs and detection levels outlined in the legislation has created a need for analytical methods to become more sensitive to ensure correct analysis. On some occasions MRL’s have been lowered which require a technology sensitive enough to detect very low concentrations in a sample.
One such screening method that is commonly used is the Enzyme-linked immunosorbent assay (ELISA) methods, which work well for testing and providing accurate results.
Randox Food have developed another method of analysis using the Evidence Investigator which uses similar methodology to ELISA methods. The analyser uses biochip array technology (BAT) to perform simultaneous quantitative detection of multiple analytes from a single sample and can be used across multiple matrix types including the products produced by the industries mentioned. The core technology is the Randox biochip, this contains an array of discrete test regions containing immobilized antibodies specific to the drug residues under test.
These methods are rapid, reliable, and sensitive so are able to detect residues in very small concentrations. The Randox methods are developed in line with EU Directive 86/469/EEC and as such are an effective testing method for multiple areas of the food industry.
For further information please contact the Randox Food Diagnostics team by emailing: firstname.lastname@example.org