Diagnosing prediabetes with the Randox Adiponectin Assay
Talking about diabetes can be tough, but it doesn’t have to be.
This month, we’re joining the conversation on diabetes to help raise awareness of the condition, and importantly, how it can be diagnosed, managed, and even prevented.
Today, our focus is on a lesser-known variant of the chronic illness and one which you may not have heard of – prediabetes.
A third of all adults in the UK have prediabetes and with the UK’s estimated 3.8million diabetics estimated to climb to 5million by 2025 – largely as a result of obesity and the ageing population – it’s more important than ever to check if you’re suffering from this pre-cursor to diabetes.
WHAT IS PREDIABETES?
Illness doesn’t just happen overnight. Over time, your body begins to display symptoms but, often, irregularly has been present for some time. Prediabetes is an early indicator of type 2 diabetes which is characterised by the presence of blood glucose levels that are higher than normal but not yet high enough to be classed as diabetes.
For this reason, prediabetes is often described as the “grey area” between normal blood sugar and diabetic levels. In the UK, around 7 million people are estimated to have prediabetes and thus have a high risk for developing type 2 diabetes.
WHAT ARE THE SYMPTOMS OF PREDIABETES?
93% of the 60 million people with prediabetes globally are unaware they have it. This is because the condition often develops gradually without any warning signs or symptoms. In many cases, the sufferer only learns of their diabetic state once the symptoms of type 2 diabetes start to appear.
TESTING FOR PREDIABETES
Traditional biomarker tests used to diagnose type 2 diabetes include Fasting Plasma Glucose, Oral Glucose Tolerance Test, and HbA1c. However, these cannot be utilised as tests for prediabetes, as beta cell damage has already occurred, and insulin insensitivity is already underway.
Adiponectin, a hormone responsible for regulating glucose metabolism has proven to be a strong predictor of type 2 diabetes at a crucial stage – before it has fully manifested.
Adiponectin’s ability to diagnose prediabetes is due to its relationship with a hazardous type of fat within the body which wraps around internal organs. This visceral fat is particularly dangerous because it can occur even within individuals deemed to have a healthy waist circumference, making them appear deceptively healthy simply because they are slim.
By measuring Adiponectin levels, clinicians can identify someone with high levels of visceral fat and therefore at risk of type 2 diabetes long before they would be identified by tests which measure blood sugar levels.
THE BENEFIT OF A PREDIABETES DIAGNOSIS
Whilst being diagnosed with prediabetes may come as a real shock, it offers a unique opportunity for lifestyle modification and prevention that is often not possible with other illnesses.
And this is because prediabetes is reversible. In fact, up to 80% of all cases of type 2 diabetes are preventable – if detected early. We want to help more and more people understand their health as early as possible so they can take reversible action now when there’s the best chance of a positive outcome.
With this information at your disposal, you can then take the necessary action to stop diabetes in its tracks.
For more information about Adiponectin; please visit https://www.randox.com/adiponectin/
To book the world’s most advanced health check which assess up to 350 different indicators of disease at their very earliest stage, including diabetes, visit www.randoxhealth.com
For further information, please contact Randox PR by emailing firstname.lastname@example.org or phoning 028 9442 2413.
This December, treat your friends and family to the greatest gift of all. The gift of health.
Throughout the month, Randox Health are offering a free Specialised Test, Cough, Cold & Flu, with every Everyman or Everywoman Programme purchased.
Examining up to 150 different indicators of health in your body! The programmes are among the most advanced in the world with our Signature Programme being the most advanced, examining up to 350 different indicators of disease and ill-health. This is due to our advanced technology.
The perfect gift, or perhaps Christmas treat for yourself? These 12-month programmes are guaranteed to give you the most advanced picture available of your current health status.
This month, each programme also comes with a free Cough, Cold & Flu check worth £100.
What is the Cough, Cold and Flu check?
In a world where warnings about antibiotic resistance make daily headlines, Randox Health is helping people take back control.
Antibiotics are used to prevent and treat antibiotic infections. But they don’t work for everything. Taking them when we don’t need them can enable dangerous bacteria that lives inside us to become resistant. That means if you need antibiotics in the future, they may not work. As the NHS says, this puts you and your family at serious risk.
Only bacterial infections can be treated with antibiotics, so finding out what’s behind your infection is essential.
With the Randox Health Cough, Cold and Flu test one swab can detect and identify the cause of 21 respiratory infections in just five hours. With this knowledge, you will find out what’s treatment is going to be appropriate for you.
Take the guesswork out of getting better and book your Cough, Cold and Flu test either as a standalone check or for free with or Everyman or Everywoman Programme.
Specialised tests are available at our clinics in London, Liverpool, Holywood and Crumlin, and also through our innovative mobile health clinic. Gift cards can be purchased from as little as £20.
To find out more about the offer or to purchase the most thoughtful of Christmas presents – a gift card for the ‘gift of health’ – please phone our team on 0800 2545 130. You can also drop them an email. email@example.com
Randox Laboratories is this month driving awareness of diabetes and the need for early and accurate diagnosis to enable patients to take preventive action before the condition worsens.
Diabetes UK have stated that diabetes is the fastest growing health threat of our times and an urgent public health issue. Statistics show that since 1996, the number of people living with diabetes has more than doubled. It has been estimated that there are 1.1 million people living with diabetes in the UK that have yet to be diagnosed, including 84,836 people in Northern Ireland.
According to Diabetes UK around 700 people a day are diagnosed with diabetes, which equates to one person every two minutes. If nothing changes, it is estimated that diabetes will affect one in ten people by 2040. This will raise diabetes prevalence from 415 million to 642 million by 2040. With current treatment taking up almost 9% of the annual NHS budget – roughly £8.8bn a year – the implications for future healthcare budgets are clear if this dangerous trend persists.
The good news however, is that recent research has found that type 2 diabetes is preventable through lifestyle changes. The NHS recently released the UK’s National Diabetes Prevention Programme which is aimed at tackling the increasing growing threat of diabetes.
However, following a warning raised by an Oxford University study, which looked into efforts of this Prevention Programme, it was found that it is unlikely to have much impact because the blood tests used were inaccurate at detecting pre-diabetes – the stage at which diabetes is reversible.
The blood tests used in the National Diabetes Prevention Programme were only effective at detecting diabetes at a stage when damage had already been done.
At Randox, we have developed a number of tests that can help detect the earliest possible signs of diabetes, often before symptoms have even manifested – including a pioneering test for the hormone Adiponectin.
Assessing Adiponectin levels allows doctors to calculate a patient’s levels of visceral fat – a dangerous, internal fat stored around organs. This deep fat, which is not visible to the naked eye, is linked to health problems including Type-2 diabetes.
Low levels of adiponectin equate to high levels of visceral fat which can be combated by improving your diet, exercise habits and even stress levels. Given that 70% of Type-2 diabetes can be prevented by lifestyle changes, there is strong correlation that by detecting low levels of Adiponectin and taking corrective and preventive action, it could result in a decrease in the numbers of people who develop the life-altering condition.
In addition to a test for the Adiponectin biomarker, Randox Biosciences have created a Metabolic Syndrome Array that measures 12 markers associated with metabolic syndrome and cardiovascular disease. Metabolic Syndrome is a is a group of cardiovascular risk factors that affects over 20% of adults and results in a person being three times more likely to have a stroke or heart attack, and five times more likely to develop diabetes.
Ultimately, we would like to see all medical professionals who are at the forefront of patient care armed with the most accurate diagnostic tools available. Updating traditional practice may not be easy but we believe it is imperative to do so, if we are to effectively challenge this global epidemic.
Randox remains focused on providing early diagnoses and preventing illnesses by providing innovative diagnostics tests that will continue to revolutionise the healthcare landscape.
For further information, please contact Randox PR by emailing firstname.lastname@example.org or phoning 028 9442 2413.
It’s a concept we’re all familiar with.
Every year we take our car to get serviced to make sure everything is in working order and to fix the things that aren’t quite right.
Even if it’s been driving smoothly, using fuel economically and experiencing no apparent issues, we get it checked out anyway, because it’s better to find the small problems before they become bigger ones. Prevention is better than cure, right?
So why should we treat our bodies any differently?
Nearly half of all faults found during car MOTs could be avoided by carrying out simple maintenance, and it’s the same when it comes to our bodies.
With 50% of cancers, 70% of cardiovascular disease and 80% of strokes being preventable, a comprehensive health MOT can provide an accurate picture of your health while you are still well and provide you with the information you need to take action to prevent future problems.
This Movember, we’re encouraging men to take a proactive approach to their health – to obtain a comprehensive understanding of their body and their health in the same way they do with their car each year.
Your body is the most important vehicle you will ever own and that’s why we provide a comprehensive menu of blood tests for 25 different aspects of your health simultaneously, whereas a standard car MOT will only test 8 different areas of your car’s health.
But that’s not surprising when you know how complex the human body is compared to a car! Or when you learn that Randox Health’s testing programme is the most comprehensive and personalised health MOT on the market.
Between three and five tests are traditionally offered in the GP setting, and even in standard healthcare companies’ ‘premium packages’, only 30-35 routine blood tests may be carried out.
Within the Randox Health Everyman Programme we offer a varied range of 150 health tests.
Much more than a standard health MOT, this full body testing makes Randox Health the world’s most advanced preventive and personalised health MOT.
By harnessing the cutting-edge Randox Health science and technology, developed over 35 years, you have the knowledge to prevent future illness, and the power to secure your health.
Contact the Randox Health team today to find out more:
Tel: 0800 2545 130
For over 36 years, Randox has been developing cutting-edge diagnostic technologies to improve the quality, accuracy and timeliness of laboratory results, because we firmly believe that access to accurate and timely diagnostics is key to improving healthcare.
As 70% of clinical decisions are based on laboratory output, our efforts are central to healthcare and improving patient outcomes. It will come as no surprise therefore that we support the announcement made by Health Secretary Matt Hancock this week about a new green paper, entitled “Prevention is better than cure,” that will argue for a shift towards preventative healthcare, to help people stay well.
On Monday Mr Hancock argued that the “numbers don’t stack up” when it comes to spending on prevention as opposed to treatment, with £97bn of public money in the UK spent on treating disease and only £8bn preventing it.
He added that “we need a new 21st century focus on prevention.”
Duncan Selbie, Chief Executive Public Health England, echoed Mr Hancock’s sentiments by saying; “We need to move from a system that detects and treats illnesses to one that also predicts and prevents poor health through promoting health in all policies and puts people back in charge of their own health.”
It’s a goal that we at Randox share with both Mr Hancock and Mr Selbie. With new and emerging diagnostic technologies, we can speed up diagnoses, improve patient outcomes, make every pound go further and give clinicians more time with their patients.
Much earlier and much more effective diagnosis can simultaneously improve healthcare outcomes and reduce the burden on healthcare services.
At Randox, we look forward to a time when sickness is actively prevented, rather than managed. By utilising innovative diagnostic products capable of diagnosing disease and ill-health at the earliest possible stage, we can truly transform the life of the patient.
For further information please email email@example.com