Total Iron Binding Capacity (TIBC)
Reagent | Total Iron Binding Capacity (TIBC)
The TIBC assay showed a correlation coefficient of 0.9 against another commercially available method
Eliminates negative bias
Traditional calculation methods using the unsaturated iron-binding capacity (UIBC) and serum iron (TIBC = UIBC + serum iron) have a significant negative bias compared with direct TIBC methods. Randox’s TIBC assay eliminates this bias
The TIBC assay has a precision of less than 4% CV
Randox Total Iron Binding Capacity (TIBC) (Colorimetric)
- Colorimetric method
- Liquid ready-to-use reagents
- Measuring range 57.7 – 672 µg/dl
- Eliminates negative bias
- Stable to expiry when stored at 2-8⁰C
- Minimal interferences
What is Total Iron Binding Capacity (TIBC) assay used for?
Iron is transported in the blood by the serum protein transferrin. Transferrin is normally 30% saturated, that is 30% of the iron-binding sites contain an iron atom. The total iron-binding capacity (TIBC) is the amount of iron needed to 100% saturate transferrin. TIBC reflects iron status: levels are elevated when iron levels are low; therefore it is useful in the diagnosis and monitoring of iron deficiency anaemia and iron deficiency in late pregnancy. Abnormal levels of TIBC can point towards a variety of disease states such as hereditary haemochromatosis, a common genetic disorder where iron levels are excessive, other anaemias, liver disease and malnutrition.