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Randox response to the Public Accounts Committee (PAC) report, ‘Government’s contracts with Randox Laboratories Ltd’

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27th July 2022: Randox response to the Public Accounts Committee (PAC) report, ‘Government’s contracts with Randox Laboratories Ltd’

A spokesperson for Randox said:

“The PAC report is deeply flawed and wrong in assumptions it makes and the conclusions it draws about Randox.

“As the UK’s largest diagnostic company, with four decades of experience, over 2,000 professional staff on hand at the start of the pandemic and more than £350m of prior investment in diagnostic and engineering innovation, Randox was uniquely situated to respond to the national need when COVID-19 emerged in early 2020.

“In supporting the UK’s urgent requirement for coronavirus testing Randox reacted with speed, efficiency and flexibility in delivering value. The company developed and built, in record time, the UK’s largest COVID-19 laboratories and testing services. It provided the Department of Health and Social Care with a PCR testing capacity at the time of greatest need, rising from 300 tests per day to 120,000 per day by January 2021.

“Altogether Randox processed over 25 million samples for UK’s National Testing Programme and in support of international travel for business and personal reasons. This played a crucial role in keeping vital elements of the UK economy functioning during lockdowns.

“In adapting to rapidly changing DHSC and Department of Transport requirements, Randox delivered unique value to the government, the national economy and to individuals.

“At no stage, either during its deliberations or in its preparation of this report, did the PAC make any contact whatsoever with Randox. Consequently many elements of its report relating to Randox are false, based as they are, on wrong and unchecked assumptions about the company. For that reason, they and any publications arising from them are the subject of a legal complaint.”

“The issues the report raises around internal DHSC record keeping are clearly a matter for DHSC”

For all media enquiries, please contact Ian Monk on ian@ianmonk.com or  +44 7970 026072 / + 44 203 011 1933

 

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Biomedical Science Day 2022

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Biomedical Science Day 2022

Biomedical Science Day is taking place this year on Thursday 9th June 2022. This is an annual celebration to increase the awareness of Biomedical Science and to promote to the public the importance of it.

Biomedical scientists play a key role in diagnosis, quality development and assurance, treatment, research, and development in the modern medical sciences. To celebrate and give recognition we have interviewed one of our RCLS clinical deputy managers, Jayme Hamilton.

 

This is what Jayme has to say about his role in Biomedical Science:

 

 

1. What attracted you to pursue a career in biomedical science?

My degree was in Biological Sciences with Professional Studies. Through it, I was able to design my degree based in my own interests and curiosities, which drew me to exploring the molecular and chemical pathways that elicit biological pathways and also how biotechnology is opening up a future to personalised health and therapies. What I find interesting it how a complete complement of biomarkers needs to be assessed to offer a full illustration of what’s going on under the skin.

2. How many different labs have you worked in?

I have been fortunate to work within several Laboratories to some capacity early in my career. I had a very fulfilling placement within a Method Development and Validation lab at a pharmaceutical company, as well as completing a challenging honours project in population genetics in my final year of university.  Since joining Randox, I have had opportunities to work across several Clinical and Molecular Laboratories with talented colleagues from all sorts of backgrounds; within Liverpool and London in England, Holywood and Antrim in N. Ireland and Los Angeles in California.

 

3. Do you enjoy the practical or theoretical aspect of biomedical science?

Theoretical- I have a drive to learn and understand and thankfully in science that is a continuous journey, as new forms of diagnostics and analysis are born and our understanding can grow or even change.  With a good understanding of the science and a multidisciplinary team of talented individuals to collaborate with, it makes executing the practical work all the more rewarding.

 

4. What is your favourite part of your day in work?

The end of the day -but not why you might think. I have been trying to be more reflective and as the start of the day can be very busy and hands on, I have found it helpful to review my workload and responsibilities, as well as that of those I help lead, at the end of the day; to better look ahead to tomorrow and acknowledge the efforts of the team.

 

5. What’s in your lab coat pocket?

Pens, markers, and more pens. My favourite being my engineering pen, with a torch and stylus included.  Thankfully we push for a more paperless world, but a busy lab can need some quick notes to be made. I’m also a very visual person and find it easiest to communicate to colleagues with notes or even a quick sketch.

 

6. In your opinion, what are the most important aspects of laboratory work?

The results we release. Fundamentally the data we release it for the benefit to the individual they deprived from. By stringently monitoring our quality checks and adhering to the procedures and processes we implement, we can have confidence that the results we release have a high level qualitative and interpretive value.

 

7. In what ways does your work make a difference to people’s lives?

At a personal level, as a clinical deputy manager I aim to optimise and evolve the duties of the colleagues I work with to make their jobs easier and more fulfilling and by extension the functionality of the lab more efficient.

In doing so, I broadly think the work we are doing as a collective, is bringing personalised testing to the masses and in doing so, add to improving the public’s understanding of science, in such that they can begin to take their health into their own hands in a measurable and meaningful way.

 

8. What is your dream career within biomedical science?

Living the dream. So far in my career I have been able to learn and develop within a profession that aligns with my interests, whilst simultaneously contributing to expanding and exciting industry. Throughout which I have had the opportunity to collaborate with many fantastic, talented, intelligent and hardworking people, from an array of disciplines, during the growth of a impressive clinical testing service as well as a nationwide covid testing service.

 

 

 

 

Jayme is a fundamental member of Randox and plays an essential role in the team, as do all our employees. Without our valuable laboratory team working extremely hard behind the scenes the lifesaving work we do here at Randox would not be possible. We thank each one of you for your hard work every day.

To find out more about our Biomedical Science, contact us at market@randox.com

 

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Randox to deliver £10m investment for major UK research project

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Diagnostics and personalised health company Randox to deliver £10m investment for major UK research project Our Future Health

Randox, the Northern Ireland-based diagnostics and personalised health company, has today been announced as one of four new industry partners in the Our Future Health (OFH) programme, which will be the UK’s largest ever health research programme.

Randox will deliver a £10m investment in the programme, which will discover and develop new methods of prevention, early detection and treatment of diseases and health conditions.

The company is one of four new partners who will deliver a total of £40m to OFH. They join 10 additional life sciences companies that were previously announced as funding partners in January 2022. As well as its £10m investment, Randox will contribute its world-leading expertise to the programme. Its network of 20 High Street clinics, including those in Holywood and Crumlin, will also be available if required to test volunteers from across the UK taking part in the OFH project. The project aims to monitor the long-term health of 5 million volunteers in the coming years, starting this autumn.

Andrew Roddam, Chief Executive of OFH, said: “We are delighted to be announcing a further four industry partners for OFH, who together will provide an additional £40m to further our objective to develop new ways to prevent, detect and treatments enabling people to live healthier lives for longer.  We welcome Randox as one of these partners, knowing their long-term commitment to diagnostics, and look forward to working with them in the months and years ahead.”

OFH has also joined with 16 health research charities, who have endorsed the pilot phase of the programme and are providing valuable support and experience.

Volunteers will be asked to complete an online health questionnaire, give their informed consent to link information from their healthcare records to OFH and donate a small blood sample.

Volunteers are also being asked to give their permission for OFH to contact them in the future to give them the opportunity to take part in follow-on research and to provide personal feedback about their health, should they wish to receive it.

Researchers from across the life sciences community, including academia, industry and the NHS, will be able to apply to study OFH resources as part of their crucial research to accelerate the discovery and development of innovative diagnostics and treatments.

Volunteers’ data will be de-identified and held in ‘trusted research environments’ that meet strict security criteria and an access board, which will include independent experts and members of the public, to ensure OFH resources are only used for health research in the public interest.

Randox Managing Director, Dr Peter FitzGerald said:

“Randox has been engaged from the very outset and is now excited to formally support this world-leading research project, both as a funding member and with our considerable expertise.

“With over 40 years of diagnostic experience, and extensive research capabilities, Randox knows that a personalised approach to the early detection and prevention of disease is not only critical to saving and extending life, but also to improving the quality of our lives. This project will further those critical goals. The ability for participants to receive feedback on their health from the project, and to engage with future research, also promotes Randox’s objective of greater individual ownership of health.

“Randox is committed to providing accessible and affordable testing to drive significant health improvements through the early detection and prevention of disease. ‘Our Future Health’ is perfectly aligned with that vision.”

Members of the public who are interested in taking part in Our Future Health later this year can register for news and updates  at www.ourfuturehealth.org.uk

 

For more information contact:
Mia Taylor
mia.taylor@woburnpartners.com
+44 (0) 7891525749
James Robinson
james.robinson@woburnpartners.com

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Celebrating Lp(a) Awareness Day 2022 today!

Randox are raising awareness for Lipoprotein(a), we want to drive awareness on tests that are available to you to decrease the risk of stroke, heart attack or other heart diseases.

Lp(a) is a risk factor for atherosclerosis and related diseases including CHD and stroke. It is increasingly recognised as the strongest known genetic risk factor for premature coronary artery disease. The biggest challenge that exists surrounding Lp(a) measurement is the heterogeneity of the apolipoprotein(a) isoforms, resulting in the underestimation or overestimation of Lp(a) concentrations.

Benefits of the Randox Lp(a) assay

WHO/IFCC reference material – The Randox Lp(a) assay is calibrated in nmol/l and traceable to the WHO/IFCC reference material (IFCC SRM 2B) and provides an acceptable bias compared with the Northwest Lipid Metabolism Diabetes Research Laboratory (NLMDRKL) gold standard method.

Dedicated calibrator & control available – Five point calibrator with accuracy-based assigned target values (in nmol/l) is available, accurately reflecting the heterogeneity of the apo(a) isoforms. Dedicated Lp(a) control is available offering a complete testing package.

Excellent correlation – A correlation coefficient of r=0.995 was displayed when the Randox method was compared against other commercially available methods.

Excellent precision – The Randox Lp(a) assay displayed a within run precision of <2.54%.

Liquid ready-to-use – The Randox Lp(a) assay is available in a liquid ready-to-use format for convenience and ease-of-use.

Applications available – Instrument-specific settings can be provided for a wide range of clinical chemistry analysers.

 

The biggest challenge that exists surrounding Lp(a) measurement is the heterogeneity of the apo(a) isoforms, resulting in the underestimation or overestimation of Lp(a) concentrations. In immunoassays, the variable numbers of repeated KIV-2 units in Lp(a) act as multiple epitopes. This is where standardisation across calibrators is vital. Unless the calibrants do have the same range of isoforms as test samples, those with higher numbers of the KIV-2 repeat, will represent with an overestimation in Lp(a) concentrations and those with smaller numbers of the KIV-2 repeat, will represent with an underestimation. The smaller isoforms are strongly associated with higher Lp(a) concentrations. Lack of standardisation of the calibrant would result in an underestimation of Lp(a) associated CVD risk. It is important to note that an Lp(a) immunoassay employing isoform insensitive antibodies does not exist.

 

DID YOU KNOW?

Lp(a) has been identified to be a key risk factor for cardiovascular complications in individuals with COVID-19!

It is well documented that pre-existing comorbidities such as diabetes and CVD are associated with greater severity and higher fatality rates in those with COVID-19.  Those with either baseline elevated Lp(a) or those whose Lp(a) levels increased following infection from COVID-19, or both, maybe at a significantly increased risk of developing thromboses. Elevated Lp(a) levels may cause acute destabilisation of pre-existing but quiescent, atherosclerotic plaques, which could induce an acute myocardial infarction or stroke.

Identifying any possible health conditions that would relate to early signs of stroke, heart attack or other heart diseases will allow you to make any decisions on an appropriate diet, lifestyle changes and early treatment to reduce your risk of further problems.

For more information about Lp(a):

Visit our website: Lipoprotein(a) [Lp(a)] | Reagents | Randox Laboratories

Or email: marketing@randox.com

 

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