Randox Laboratories and Roquefort Therapeutics Collaborate to Develop Midkine Cancer Antibodies
Randox Laboratories and Roquefort Therapeutics Collaborate to Develop Midkine Cancer Antibodies
Randox and Roquefort Therapeutics collaborate to develop midkine cancer antibodies
Randox Laboratories collaborate with Roquefort Therapeutics, an LSE market listed biotech company, dedicated to developing first in class medicines in the high value, high growth oncology market. The partnership is focused on the field of medical diagnostics only, in relation to Roquefort’s Midkine antibody portfolio.
The collaboration Randox will allow to utilise Roquefort’s Midkine antibodies in the field of medical diagnostics. Randox will therefore engage with Roquefort in research programmes to identify new cancer diagnostics that will be treatable with the companies Midkine products.
Why this partnership is important?
Midkine is a herapin binding protein, known for being important in embryonic development. While normally undetected in healthy adults, it is often highly expressed in cancer, inflammatory conditions and autoimmune disorders. Extensive research has revealed that blocking Midkine with antibodies can help slow tumour growth, reduce metastasis and overcome treatment resistance.
Within the partnership, Randox focuses on medical diagnostics to detect cancers expressing Midkine, produce the diagnostics essential for clinical trials and help Roquefort Therapeutics remain focused on developing first in class oncology medicines.
Randox are highly committed to preventative healthcare through early and more accurate diagnostics therefore this partnership with Roquefort Therapeutics is vitally important. Early diagnosis significantly increases a patient’s chance of survival thus using medical diagnostics to identify patients with cancer expressing Midkine is essential to the development of first-in-class cancer medicines and the future of cancer treatments.
When talking about the partnership, Dr Peter Fitzgerald, Managing Director of Randox said
About Roquefort Therapeutics
Roquefort Therapeutics is a cancer focused biotech company developing first in class drugs in the high value and high growth oncology segment prior to partnering or selling to big pharma. Since listing in March 2021, Roquefort successfully acquired Lyramid Pty Ltd, a leader in the development of medicines for a new therapeutic target, Midkine and has since developed a leadership position in Midkine intellectual property.
Roquefort Therapeutics’ focused portfolio consists of four fully funded, novel patent protected, pre-clinical, anti-cancer medicines that include:
- Midkine antibodies with significant in vivo efficacy and toxicology studies
- Midkine RNA therapeutics with novel anti-cancer gene editing action
- MK cell therapy with direct NK-mediate anti-cancer action and
- SiRNA targeting novel STAT-6 target in solid tumour showing significant in VIVO efficacy.
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Randox to deliver £10m investment for major UK research project
Diagnostics and personalised health company Randox to deliver £10m investment for major UK research project Our Future Health
Randox, the Northern Ireland-based diagnostics and personalised health company, has today been announced as one of four new industry partners in the Our Future Health (OFH) programme, which will be the UK’s largest ever health research programme.
Randox will deliver a £10m investment in the programme, which will discover and develop new methods of prevention, early detection and treatment of diseases and health conditions.
The company is one of four new partners who will deliver a total of £40m to OFH. They join 10 additional life sciences companies that were previously announced as funding partners in January 2022. As well as its £10m investment, Randox will contribute its world-leading expertise to the programme. Its network of 20 High Street clinics, including those in Holywood and Crumlin, will also be available if required to test volunteers from across the UK taking part in the OFH project. The project aims to monitor the long-term health of 5 million volunteers in the coming years, starting this autumn.
Andrew Roddam, Chief Executive of OFH, said: “We are delighted to be announcing a further four industry partners for OFH, who together will provide an additional £40m to further our objective to develop new ways to prevent, detect and treatments enabling people to live healthier lives for longer. We welcome Randox as one of these partners, knowing their long-term commitment to diagnostics, and look forward to working with them in the months and years ahead.”
OFH has also joined with 16 health research charities, who have endorsed the pilot phase of the programme and are providing valuable support and experience.
Volunteers will be asked to complete an online health questionnaire, give their informed consent to link information from their healthcare records to OFH and donate a small blood sample.
Volunteers are also being asked to give their permission for OFH to contact them in the future to give them the opportunity to take part in follow-on research and to provide personal feedback about their health, should they wish to receive it.
Researchers from across the life sciences community, including academia, industry and the NHS, will be able to apply to study OFH resources as part of their crucial research to accelerate the discovery and development of innovative diagnostics and treatments.
Volunteers’ data will be de-identified and held in ‘trusted research environments’ that meet strict security criteria and an access board, which will include independent experts and members of the public, to ensure OFH resources are only used for health research in the public interest.
Randox Managing Director, Dr Peter FitzGerald said:
“Randox has been engaged from the very outset and is now excited to formally support this world-leading research project, both as a funding member and with our considerable expertise.
“With over 40 years of diagnostic experience, and extensive research capabilities, Randox knows that a personalised approach to the early detection and prevention of disease is not only critical to saving and extending life, but also to improving the quality of our lives. This project will further those critical goals. The ability for participants to receive feedback on their health from the project, and to engage with future research, also promotes Randox’s objective of greater individual ownership of health.
“Randox is committed to providing accessible and affordable testing to drive significant health improvements through the early detection and prevention of disease. ‘Our Future Health’ is perfectly aligned with that vision.”
Members of the public who are interested in taking part in Our Future Health later this year can register for news and updates at www.ourfuturehealth.org.uk
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Randox Professor of Medicine: Ulster University Announces Creation of New Role at Brand New School of Medicine
Wednesday 23 June 2021
Ulster University Announces Creation of New Role at Brand New School of Medicine: the Randox Professor of Medicine
Ulster University has received £1.2million in funding for medical education and research from Randox Laboratories Ltd. Thanks to this generous donation from Randox Laboratories, the University is creating its first Professor of Medicine post, to be titled, the Randox Professor of Medicine.
This will be a clinical and academic post so the appointee to the Randox Professorship will provide educational leadership, teaching and training thus inspiring the next generation of doctors and researchers in the area.
Alongside education, the post holder will develop a research portfolio in line with the research strategy of the School of Medicine and ambitions included in the Health Research Institute-THRIVE (HRI-THRIVE) Project as part of the Derry and Strabane City Deal.
The successful appointee to the Randox Professorship will have an outstanding track-record in medical research with the experience, vision and enthusiasm to build on current strengths in the University and develop a leading research presence in the School of Medicine.
The Randox Professor will be part of a vibrant and intellectually stimulating translational research community both within the School of Medicine and C-TRIC and will have access to the leading research facilities which the University offers. They will have the opportunity to collaborate with existing researchers in personalised medicine and influence the research and innovation direction of the proposed THRIVE Research Units that currently include: Blood Cancer; Cardiovascular Research and Improvement Science; Neuromuscular Health (Motor Neuron Disease, MS, Parkinson’s Disease); Brain Health (Depression, psychosis, Alzheimer’s Disease); Orthopaedic and Rheumatic Health; and Multiple Long-term Conditions.
The Randox professor will deliver clinical care within the Western Trust, contributing directly to patient care and improving health outcomes for our local community.
Dr Catherine McDonnell, Medical Director at the Western Trust, is excited at the new appointment:
“This is a unique opportunity, and shows what can be achieved with collaborative working and by forging partnerships between organisations.
“The Randox Professorship will play a crucial role in the delivery of patient care in the months and years ahead, and will help us bring in fresh expertise to what is already a very strong team on the ground.
“We would like to thank both Ulster University and Randox Laboratories for partnering in this exciting venture, which we believe will have a very positive impact on our patients and the Western Trust overall.”
Pictured left to right are Dr Peter FitzGerald, Managing Director, Randox Laboratories, and Professor Paul Bartholomew, Vice-Chancellor at Ulster University
The post will report into the Foundation Dean of the School of Medicine and recruitment will commence in the coming weeks.
The role will be supported by Randox Laboratories for a period of 5 years.
Dr Peter FitzGerald, Managing Director, Randox Laboratories said:
“At this time of rapid and significant change within medicine, it is imperative that industry, academia and medical education are aligned to improve both patient outcomes and the efficiency of healthcare services. The announcement of the new post of Randox Professor of Medicine within the new Ulster University School of Medicine shows our commitment to these critical national priorities. Ulster University and Randox are both renowned globally for healthcare research and education, particularly in the field of diagnostics, and together provide a vital platform to support the next generation of aspirational clinicians – to develop critical skills, make a positive difference to patient healthcare around the world, and cement Northern Ireland’s reputation as a global hub for life sciences.”
Professor Paul Bartholomew, Vice-Chancellor at Ulster University added:
“By opening the School of Medicine in August we are committing to address the acute shortage of doctors in Northern Ireland and to recruit students and staff who will be locally focused yet globally ambitious. The appointment of the Randox Professor of Medicine will enable us to further this ambition and allow us to enhance the University’s existing expertise and research excellence in personalised medicine diagnostics and contribute to expanding the medical diagnostics sector. With the strong emphasis on personalised medicine in the Derry and Strabane City Deal, the Randox Professor of Medicine will join us at an exciting time for the region.
“The University sees the ground breaking Randox Professorship as an opportunity to further our long standing partnership with Randox so that we might together have a unique opportunity to support clinical medicine, enhance the quality of patient care through highly relevant translational research and inspire the next generation of doctors.”
Professor Louise Dubras, Foundation Dean, School of Medicine at Ulster University, added:
“As we look forward to our first students arriving in August this year, we are excited to be progressing this role, the first of our “second wave”, to complement the exceptional staff team in place to deliver the first year of the programme. This is a unique and exciting opportunity for an inspirational academic clinical leader to shape the direction of clinical and translational research within the School of Medicine. I’m looking for an outstanding candidate with a wealth of teaching experience and a passion for related research which will inform teaching. This candidate will join me and the incredible team we have put together to teach the doctors of the future.”
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Randox is new patron for NI Chamber of Commerce
25th MARCH 2021
Northern Ireland Chamber of Commerce and Industry (NI Chamber) has announced that Randox, the UK and Ireland’s largest diagnostics company, is its newest Patron organisation.
As a new NI Chamber Patron, Randox joins a select group of leading businesses, who lend their support to the development of the region’s economy and business community. The partnership offers mutual benefit and will see Randox experience increased brand exposure among the business community and close association with a leading membership organisation.
Announcing the partnership, Ann McGregor, Chief Executive, NI Chamber said:
“Randox has a long relationship with NI Chamber and I am delighted to announce that the company has decided to strengthen its association with us, by coming on board as a Patron.
“Having the support of one of Northern Ireland’s leading exporters is a real endorsement of the work we do and in particular, the support NI Chamber has provided to companies over the past 12 months. As we continue to help firms in all sectors to restart and grow, we look forward to working with Randox and indeed all of our Patrons.”
Dr Peter FitzGerald, Managing Director of Randox, added:
“We are delighted to be welcomed as a patron of Northern Ireland Chamber of Commerce and Industry. As a leading life science company with global export markets, Randox very much values the contribution of the Chamber – particularly so at a time of significant change related to Brexit and the impact of COVID-19. We are ambitious for the future and see the potential for significant growth, as the importance of diagnostics and preventative healthcare grows. We look forward to working with Ann and the Chamber team as we rise to meet the challenges and seize the opportunities to grow our economy – for the benefit of all our people.”
Established in 1982, Randox is the largest diagnostics company from the UK and Ireland; focusing on the provision of accurate and timely health testing. By identifying risk to health, improving clinical diagnoses and promoting preventative healthcare, Randox technologies are used to achieve better health outcomes whilst reducing the burden on clinical services. The company’s innovative and comprehensive portfolio includes tests for diabetes, Alzheimer’s disease, cancer, stroke and COVID-19. In 2019 Randox manufactured over 4 billion tests, and operated in 145 countries. With over 2000 staff, including more than 450 research scientists and engineers, key facilities are located in Co Antrim and Co Donegal.
Randox joins a list of NI Chamber Patrons which also includes Caterpillar, Danske Bank, DSV, fonaCAB, Investec, Moy Park, Pinsent Masons, Power NI, Queen’s University, Ulster Bank, Ulster Carpets and Ulster University Business School.
For further information please email Amy Millar, Public Relations Team Leader on firstname.lastname@example.org or 028 9442 2413
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Randox Charity Partners 2019/20 Announced
Global healthcare company Randox Laboratories has today announced Liverpool-based charity the Tim Cogley Cardiac Screening Foundation, located near its Liverpool Randox Health clinic, and Townland Boxing Club, near its Crumlin headquarters in Northern Ireland, as its official charity partners for 2019/2020.
Randox staff in the UK and Ireland will be fundraising for these causes through a range of events and initiatives throughout the year, including individual staff fundraising activities and the company’s popular Christmas Raffle for staff in December.
Randox Founder and Managing Director, Dr. Peter FitzGerald, commented;
“We are delighted to partner with the Tim Cogley Cardiac Screening Foundation in Liverpool and Townland Boxing Club in Glenavy. Both are very worthy causes close to the hearts of those living near two of our health check clinics – Randox Health Liverpool in Exchange Station and Randox Health Crumlin in Northern Ireland.
“Our partnerships with each of these charities focus on the health and wellbeing, in particular, of young people. You are never too young to start caring about your health and thinking of your future wellbeing.
“Indeed, our research and development teams have found that signs of ill-health often appear in the body at an early age but symptoms may not appear until later in life. It is paramount that the health of young people is prioritised at the earliest stage and when preventable illnesses and conditions can be stopped in their tracks or more effectively managed.”
Frank Cogley, father of Tim and founder of the Tim Cogley Cardiac Screening Foundation, commented;
“The Tim Cogley Cardiac Screening Foundation is dedicated to providing free cardiac screenings and education for young adults in Merseyside and the Wirral. The essence of the charity, and its whole approach of reaching out to help others, reflects Tim’s character and, in that sense, keeps alive his driving force. I can’t imagine a legacy more in tune with the generous, kind and supportive person that was Tim.”
Tim Cogley, an apparently fit and healthy 34-year-old from Heswall, England, suffered a fatal heart attack in April 2017. Despite showing no symptoms, Tim had a 75% cholesterol blockage of the left descending coronary artery. The Tim Cogley Cardiac Screening Foundation was set up by family and friends in Tim’s memory to offer free heart screening to those aged 18 to 40 within the Merseyside area, an age range where little heart screening currently is offered.
“We have enjoyed a close working relationship with Randox Health Liverpool since our inception in 2017 and are thrilled to have been chosen as one of the company’s staff charity partners.
“The money raised by Randox staff will help provide cardiac screenings and facilitate a range of educational programmes which, by sharing Tim’s story, will illustrate the need to be aware of key health indicators from a young age.
“Making young people aware of their vital signs, such as blood pressure, will go a long way in preventing future young deaths from preventable heart conditions, and we look forward to delivering this message with the help of staff from Randox Health.”
In addition to cardiac screening programmes, the Tim Cogley Cardiac Screening Foundation is committed to delivering positive, action-focused and life-changing educational sessions which focus on delivering information lifestyle changes which can have positive benefits for young people.
Randox Founder and Managing Director, Dr. Peter FitzGerald, said;
“The Tim Cogley Cardiac Screening Foundation has already made a difference to young people in the Liverpool area both with the detection of early cardiac issues through its free screening programme and in its education endeavours. The story of Tim Cogley is a tragic one of a life ended too soon. The courage and commitment of his family to create a positive legacy in his name is to be admired and we look forward to joining with them through this Randox staff charity partnership.”
Randox’s second charity partner, Townland Boxing Club in Glenavy, was founded in 2008 by a group of dedicated people interested in the sport of boxing and improving youth facilities in the area.
The amateur boxing club, which is a completely voluntary organisation, was opened with a purpose to give young people in the area a place to meet, form friendships and learn the discipline, respect and skill required to become an amateur boxer.
Thomas Quinn, head coach at Townland Boxing Club, said;
“Randox is a key employer in the area with tremendous influence and we look forward to partnering with them as we continue to bring boxing facilities and training to young people in the wider Glenavy area. From the admin staff to coaches, everyone here works on a voluntary basis and we rely on the generosity of others, such as Randox, to keep our services continuing for generations to come.”
Randox Founder and Managing Director, Dr. Peter FitzGerald, said;
“Randox’s global headquarters has been based in Crumlin since the company was founded in 1982. We are proud to hold longstanding relationships with the local community here and our new staff charity partnership with Townland Boxing Club in Glenavy signals our continued commitment to the wellbeing of Crumlin and the surrounding area.”
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We Are Randox | Randox sets sail in AWARE NI’S Dragon Boat race
It was all hands on deck on Saturday 29th June 2019 as Team Randox competed in a Dragon Boat Race on the River Lagan for our charity partner AWARE NI.
The race took place at Cutter’s Wharf on Stranmillis Embankment in Belfast and featured fourteen different boats from ten NI businesses all vying to claim the top spot.
Other businesses taking part included Suki Tea, Anytime Fitness, Mivan, First Stop Solutions, Nanthealth, ABL Insurance, Rapid 7, Smiley Monroe and BNP Parabis.
Randox’s two boats fared well against their eager competitors. Randox Boat 1 won one of their two races against ABL Insurance Boat 1 while Randox Boat 2 impressively won both of their timed races against ABL Insurance Boat 2.
Randox Boat 2 even sailed in to the top four boats taking part, and the semi-final of the day’s events. However, the team narrowly missed out on a place in the final after a close defeat by Mivan Boat 2.
Randox 1 v ABL Insurance 1
Randox 2 v ABL Insurance 2
Randox 2 v Mivan 2
Congratulations to the team from Rapid 7 who were the overall winner on the day and of course a massive well done to all the Randox staff members who took part. A fantastic day was enjoyed by all with over £10,000 being raised collectively by all the teams taking part.
AWARE NI is one of Randox’s charity partners and is the depression and bipolar charity for Northern Ireland. We have been proud to partner with them throughout 2018 and 2019, raising awareness and funds for this vital work through a range of different events.
For further information about our work with our two charity partners, AWARE NI and Ulster University’s Mind Your Mood, please contact the Randox PR team by emailing firstname.lastname@example.org
HEATS: Randox boat 1 v ABL Insurance boat 1
HEATS: Randox boat 2 v ABL Insurance boat 2
SEMI-FINAL: Randox boat 2 v Mivan boat 2
We Are Randox | Randox Wears Yellow for World Mental Health Day 2018
Today is World Mental Health Day and Randox is getting involved to raise money for our two charity partners – AWARE NI and Ulster University’s Mind Your Mood.
Colleagues across Randox sites in Northern Ireland have been donning yellow in order to raise awareness of mental health and wellbeing and also to raise funds for these two fantastic causes.
Wear Yellow Wednesday is part of a series of events taking place at Randox as part of Randox Mental Health & Wellbeing Month – an initiative which encourages staff to take care of their mental wellbeing and seeks to support the work of AWARE NI and Mind Your Mood.
The month also entails a charity ‘freefall’ abseil from the dome of Victoria Square when 14 brave Randox colleagues will scale the heights to raise money for AWARE NI. You can visit their JustGiving page here: https://www.justgiving.com/teams/RANDOXAWARE
AWARE NI is the depression charity for Northern Ireland. They have two offices in both Belfast and Derry. AWARE has an established network of 25 support groups in rural and urban areas across the country which are run by trained volunteers. AWARE also deliver mental health and well being programmes into communities, schools, colleges, universities and workplaces.
Ulster University’s Mind Your Mood initiative is a service managed by Student Support but designed and delivered by students to have lived experiences of mental health illness. Mind Your Mood was created to help build resilience to avoid mental illness, provide support at the earliest point to avoid progression of mental illness to something more serious and threatening and to build resilience and awareness and provide support to help students with already-diagnosed mental illness.
For more information on Randox Mental Health & Wellbeing Month please contact the Randox PR team on 028 9442 2413 or by emailing email@example.com
Randox launches Mental Health & Wellbeing Month
Randox Health Holywood is this week hosting a fundraising event for mental health charities AWARE NI and Ulster University’s Mind Your Mood to launch Randox’s Mental Health & Wellbeing Month throughout October.
Held on Saturday 6th October 2018, 10am – 12noon, the health check company’s coffee morning event will offer customers, visitors and the residents of Holywood the opportunity to call in, grab a tea or coffee, and sample some scones and sweet treats, all while helping to raise money for those who need it most.
By shining a light on mental health issues, Randox hopes to educate its staff on how to look after their mental health while also raising funds for its two official charity partners. The fundraising coffee morning launches a month of staff initiatives including a Wear Yellow for World Mental Health Day on Wednesday 10th October, a company-wide Bake Sale on Friday 26th October, and a freefall abseil from the dome of Victoria Square Belfast on Sunday 21st October.
Randox Founder and Managing Director, Dr Peter FitzGerald, commented;
“Every one of us has been touched either directly or indirectly by these issues and it’s something we at Randox wish to help to address. We have for example invested significantly in research that will determine how problems with the digestive system can affect your mood, sleep and stress levels. We hope that our partnerships not only help those affected by mental ill-health across Northern Ireland, but also empower our Randox staff to take care of their own mental well-being.”
AWARE NI is the depression charity for Northern Ireland with an established network of 23 support groups in rural and urban areas across the country, all run by trained volunteers. AWARE deliver mental health and wellbeing programmes in to communities, schools, colleges, universities and workplaces while also running a 24hr email help service.
Mind Your Mood, managed by Ulster University, is designed and delivered by students who have life experience of mental health illness to help other students avoid mental illness, provide support at the earliest point, build awareness of mental illness and provide support to students who are already diagnosed with mental illness.
Donations for the Randox Team Abseil can be made here: https://www.justgiving.com/teams/RANDOXAWARE
For more information about Randox Mental Health & Wellbeing Month, please contact RandoxPR@randox.com.
Randox and Ulster University team up to support athletes of the future
Randox has joined forces with Ulster University in a major university-wide sports sponsorship deal.
The investment will supply kit and equipment for 70 sports clubs across the university including basketball, GAA, hockey and soccer. Randox will also be the main sponsor of the Freshers Fayres across the four Ulster University campuses and the universities Colours Sports Awards.
Professor Alastair Adair Deputy Vice-Chancellor Ulster University said:
“Ulster University and Randox enjoy a longstanding partnership built around research, knowledge sharing, collaboration and student opportunity which reflects the leadership of both organisations in diagnostics and health research globally. We are very encouraged that one of our valued industry partners is now supporting us as we work to develop our students striving for success in the sporting world.”
Nigel Dobson, Head of Sport Services, Ulster University said:
“Ulster University is recognised as a leading university for sport on the island of Ireland, from our sporting successes to our academic excellence and world-leading research in physical activity and exercise science. This major sponsorship deal will enable us to invest in young and aspiring coaches by providing mentoring support and coach education opportunities for the coaches of the future. We look forward to working with the team at Randox as we enable the next generation of sporting stars to reach their full potential.”
Lyndsay Rodgerson Senior Recruitment Consultant, Randox Laboratories, said:
“We have worked closely with Ulster University for many years, enjoying a mutually beneficial relationship that has seen the development of a diverse range of industrial-academic opportunities.
“Our successful and ongoing partnership continues to evolve and this year alone has seen a Randox-sponsored GAA tour of China, the launch of the Randox-Ulster University-Industrial PhD Academy and the adoption of Ulster University’s Mind Your Mood initiative as Randox’s official charity partner. We are delighted that our collaboration with this renowned university has now grown to include a university-wide sports sponsorship which will continue to benefit students long in to the future.
“Randox is passionate about fostering talent – whether that be in sport or science – and about promoting health and wellbeing across the age spectrum, and we see the sponsorship as a brilliant opportunity to nurture the young sporting talents of Northern Ireland. There may be players amongst the ranks of Ulster University’s sports teams who join Randox as part of their placement year, or who take up a graduate position with us in the years to come, and we look forward to supporting these students as they thrive in both the sporting and academic spheres.”
For more information about the Randox – Ulster University partnership, please contact the Randox PR team by emailing firstname.lastname@example.org