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EVENTS CALENDAR 2023

Randox Events Calendar

After a previously successful year of reopenings and in-person events,  Randox are pleased to announce our presence at the below events. These events present a great opportunity for Randox to share our wealth of new products and innovative technologies with the industry. We look forward to making this final transition back to business as usual. Check out below what events Randox will be attending this year. We hope to see you there!

EVENT: Medlab Middle East, 2023

DATES: 06 February – 09 February 2023

Randox are attending Medlab Middle East on 6th  – 9th February 2023.

Visit the Medlab Middle East website here

EVENT: Belgian Society of Cardiology, 2023

DATES: 09 February – 10 February 2023

Randox are attending Belgian Society of Cardiology congress on 9th – 10th February 2023.

Visit the Belgian Society of Cardiology website here

EVENT: IACR, 2023

DATES: 22 February – 24 February 2023

Randox are attending the International Association for Cryptologic Research on 22nd – 24th February 2023.

Visit the IACR website here

EVENT: CLEC 2023

DATES: 02 March – 04 March 2023

Randox are attending CLEC on 2nd – 4th March 2023.

Visit the CLEC website here

EVENT: BioMed-J 2023

DATES: 09 March – 10 March 2023

Randox are attending BioMed-J on 9th – 10th March 2023.

Visit the BioMed-J website here

EVENT: APHLS Infectious Disease Laboratory Conference 2023

DATES: 13 March – 15 March 2023

Randox are attending APHLS Infectious Disease Laboratory Conference on 13th – 15th March 2023.

Visit the APHLS website here

EVENT: Australian Summer Grains Conference 2023

DATES: 13 March – 15 March 2023

Randox are attending the Australian Summer Grains Conference on 13th – 15th March 2023.

Visit the Australian Summer Grains Conference website here

EVENT: Laborama Expo 2023

DATES: 16 March – 17 March 2023

Randox are attending the Laborama Expo on 16th – 17th March 2023.

Visit the Laborama Expo here

EVENT: SANAC 2023

DATES: 16 March – 18 March 2023

Randox are attending SANAC on 16th – 18th March 2023.

Visit the SANAC website here

EVENT: 4th Annual Infectious Disease and Molecular Diagnostics Conference 2023

DATES: 23 March – 24 March 2023

Randox are attending the 4th Annual Infectious Disease and Molecular Diagnostics Conference on 23rd – 24th March 2023.

Visit the 4th Annual Infectious Disease and Molecular Diagnostics Conference website here

EVENT: AMCLI 2023

DATES: 24 March – 27 March 2023

Randox are attending AMCLI on 24th – 27th March 2023.

Visit the AMCLI website here

EVENT: BioMedica 2023

DATES: 27 March – 28 March 2023

Randox are attending BioMedica on 27th – 28th March 2023.

Visit the BioMedica website here

EVENT: POCT Innovators 2023

DATES: 28 March 2023

Randox are attending POCT Innovators on 28th March 2023.

Visit the POCT Innovators website here

EVENT: AD/PD 2023

DATES: 28 March – 01 April 2023

Randox are attending AD/PD on 28th – 1st April 2023.

Visit the AD/PD website here

grand n

EVENT: The Grand National 2023

DATES: 13 April – 15 April 2023

Randox are attending The Grand National on 13th – 15th April 2023.

Visit The Grand National website here

EVENT: ECCMID 2023

DATES: 15 April – 18 April 2023

Randox are attending ECCMID on 15th – 18th April 2023.

Visit the ECCMID website here

EVENT: Microbiology Society 2023

DATES: 17 April – 20 April 2023

Randox are attending the Microbiology Society on 17th – 20th April 2023.

Visit the Microbiology Society website here

EVENT: COLA 2023

DATES: 03 April – 04 May 2023

Randox are attending COLA on 3rd – 4th May 2023.

Visit the COLA website here

EVENT: EuroMedLab 2023

DATES: 21 May – 25 May 2023

Randox are attending EuroMedLab on 21st – 25th May 2023.

Visit the EuroMedLab website here

EVENT: Precision Med Exhibition & Summit 2023

DATES: 23 May – 24 May 2023

Randox are attending Precision Med Exhibition & Summit on 23rd – 24th May 2023.

Visit the Precision Med Exhibition & Summit website here

EVENT: ESHG 2023

DATES: 10 June – 13 June 2023

Randox are attending ESHG on 10th – 13th June 2023.

Visit the ESHG website here

EVENT: Clinical Lab Expo 2023

DATES: 15 June – 17 June 2023

Randox are attending Clinical Lab Expo on 15th – 17th June 2023.

Visit the Clinical Lab expo website here

EVENT: ASM Microbe 2023

DATES: 15 June – 19 June 2023

Randox are attending ASM Microbe on 15th – 19th June 2023.

Visit the ASM Microbe website here

EVENT: 48th CBAC 2023

DATES: 18 June – 21 June 2023

Randox are attending the 48th CBAC on 18th – 21st June 2023.

Visit the 48th CBAC website here

 

EVENT: Analytica 2023

DATES: 11 July – 13 July 2023

Randox are attending Analytica on 11th – 13th July 2023.

Visit the Analytica website here

EVENT: Medlab Asia 2023

DATES: 12 July – 14 July 2023

Randox are attending Medlab Asia on 12th – 14th July 2023.

Visit the Medlab Asia website here

EVENT: AACC 2023

DATES: 23 July – 27 July 2023

Randox are attending AACC on 23rd – 27th July 2023.

Visit the AACC website here

EVENT: 55th Brazilian Congress of Clinical Pathology Laboratory Medicine 2023

DATES: 05 September – 08 September 2023

Randox are attending 55th Brazilian Congress of Clinical Pathology Laboratory Medicine on 5th – 8th September 2023.

Visit the 55th Brazilian Congress of Clinical Pathology Laboratory Medicine website here

EVENT: IBMS 2023

DATES: 25 September – 28 September 2023

Randox are attending IBMS on 25th – 28th September 2023.

Visit the IBMS website here

EVENT: CB&CD 2023

DATES: 26 September – 29 September 2023

Randox are attending CB&CD on 26th – 29th September 2023.

Visit the CB&CD website here

EVENT: The Pharmacy Show 2023

DATES: 15 October – 16 October 2023

Randox are attending The Pharmacy Show on 15th – 16th October 2023.

Visit The Pharmacy Show website here

medica 2

EVENT: Medica 2023

DATES: 13 November – 16 November 2023

Randox are attending Medica on 13th – 16th November 2023.

Visit the Medica website here

JIB

EVENT: JIB ‘Journées de l’innovation Biologique’ 2023

DATES: 01 December – 02 December 2023

Randox are attending JIB ‘Journées de l’innovation Biologique’ on 1st – 2nd December 2023.

Visit the JIB ‘Journées de l’innovation Biologique’ website here

 

 


5th Generation Bile Acids Assay

5th Generation Bile Acids

A Superior Method for Intrahepatic Cholestasis of Pregnancy (ICP) Testing

Benefits of the Randox 5th Generation Bile Acids Assay

Superior Performance

Superior methodology

Utilising the advanced enzyme cycling method, the Randox 5th generation bile acids assay displayed outstanding sensitivity and precision when compared to the traditional enzymatic based tests.

 

Measuring range

Excellent measuring range

The Randox 5th generation bile acids assay has a measuring range of 2.16 – 238µmol/l for the comfortable detection of clinically important results.

 

Correlation

Exceptional correlation

A correlation coefficient of r=0.99 was displayed when the Randox method was compared against other commercially available methods.

 

Liquid ready-to-use

Liquid ready-to-use

The Randox 5th generation bile acids is available in a liquid ready-to-use format for convenience and ease-of-use.

 

Calibrator & Controls

Calibrator and controls available

Calibrator and controls are available offering a complete testing package.

 

Applications available

Applications available detailing instrument-specific settings for the convenient use of the Randox 5th generation bile acids assay on a variety of clinical chemistry analysers.

 

A 4th generation method for bile acids testing is also available which offers an excellent linearity up to 150µmol/l. Applications available detailing instrument-specific settings for the convenient use of the Randox 4th generation bile acids assay on a variety of clinical chemistry analysers.

 

  • Ordering Information
  • INTRAHEPATIC CHOLESTASIS OF PREGNANCY
  • TRADITIONAL DIAGNOSTIC TESTING
  • THE FIFTH GENERATION TEST
Cat NoSize
BI7982R1 6 x 50ml
R2 6 x 18ml
EnquireKit Insert RequestMSDSBuy Online
BI3863R1 2 x 18ml
R2 2 x 8ml
EnquireKit Insert RequestMSDSBuy Online

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

Intrahepatic cholestasis of pregnancy (ICP) or obstetric cholestasis is a pregnancy-specific liver disorder. ICP, characterised by maternal pruritus in the absence of a rash and increased total bile acids (TBA) levels, is a severe form, yet reversible, cholestasis commonly occurring in the second and third trimester of pregnancy. Diagnostic and therapeutic guidelines are lacking for ICP which is of concern as ICP can have significant foetal risks 1, 2.

ICP restricts the flow of bile through the gallbladder causing bile acids to build-up in the liver 2. Due to the build-up, bile acids leak into the bloodstream where they are detected at concerning levels.  It has been documented that TBA levels in ICP can reach as high as 100 times the upper limit of a normal pregnancy. Moreover, a doubling in maternal serum TBA levels, results in a 200% increased risk of stillbirth. Additionally, elevated serum bile acids can affect the foetal cardiovascular system causing issues such as cardiac rhythm disturbances 3.

Whilst other liver function tests exist, including: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT) and bilirubin; TBA testing is thought to be the most beneficial method for the diagnosis and monitoring ICP. Moreover, TBA measurements are believed to be the most beneficial when tested in conjunction with standard liver tests, offering unrivalled sensitivity enabling the identification of early stage hepatic dysfunction 3.

The enzyme cycling method enables signal amplification through cycled regeneration reactions. In the presence of Thio-NAD, the enzyme 3-α hydroxysteroid dehydrogenase (3-α HSD) converts bile acids to 3-keto steroids and Thio-NADH (Fig. 1).  The reaction is reversible and 3-α HSD can convert 3-keto steroids and Thio-NADH to bile acids and Thio-NAD.  In the presence of excess NADH, the enzyme cycling occurs efficiently and the rate of formation of Thio-NADH is determined by measuring specific change of absorbance at 405nm 5.

Fig 1: Enzyme cycling assay principle 5
Fig 1: Enzyme cycling assay principle (5th Generation Bile Acids)

Want to know more?

Contact us or download the Total Bile Acids Whitepaper.

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Reagents Resource Hub


Featured Reagent – Cystatin C

Featured Reagent | Cystatin C

Kidney Disease

Kidney disease is a huge global health crisis, increasing healthcare costs, mortality and morbidity rates.  The global prevalence of chronic kidney disease (CKD) has continued to rise during a short lifespan.  In 2016, 1 in 10, equivalent to 10 percent of the global population were identified with having CKD with the highest prevalence’s reported in Europe, the Middle East, East Asia and Latin America, estimated at 12 per cent and the lowest in South Asia, estimated at 7 percent1.

The early risk assessment of renal function is vital.  In 1990, CKD was ranked the 27th leading cause of death in the Global Burden of Disease study2, rising to 18th 3 in 2010, 13th in 20132 and 12th by 2015.  From 2005-2015, the overall CKD mortality rate has risen by 31.7 percent, accounting for 1.1 million deaths globally in 20154.

Inadequacies of Traditional CKD Biomarkers

The most commonly used screening test for renal impairment is creatinine.  When testing for CKD using creatinine, certain factors must be taken into consideration, including: age, gender, ethnicity, and muscle mass.  As such, black men and black women will present with higher creatinine levels compared to white men and white women respectively5.

Serum creatinine is not an adequate screening test for renal impairment in the elderly (65 years of age and over) due to their decreased muscle mass.  As such, patients are misdiagnosed, thus, patients with severe renal failure are receiving suboptimal care6.

The main disadvantage of using creatinine to screen for renal impairment is that up to 50 percent of renal function can be lost before significant creatinine levels become detectable as creatinine is insensitive to small changes in the glomerular filtration rate (GFR).  Consequently, treatment is not provided at the appropriate time which can be fatal, thus, an earlier and more sensitive biomarker for renal function is vital7.

Biological Significance

Cystatin C is a small (13 kDa) cysteine proteinase inhibitor, produced by all nucleated cells at a constant rate.  Cystatin C travels through the bloodstream to the kidneys where it is freely filtered by the glomerular membrane, resorbed and fully catabolised by the proximal renal tubes.  Consequently, cystatin C is the ideal biomarker of GFR function8.

Clinical Significance of Cystatin C

The National Institute for Health and Care Excellence (NICE) (2014) guidelines recommend cystatin C testing due to its higher specificity for significant disease outcomes than those based on creatinine. As such, eGFR cystatin C measurements will significantly reduce the number of misdiagnosed patients, thus reducing the overall CKD burden9.

In 2017, a systematic literature search found 3,500 investigations into cystatin C as a marker of GFR. The study concluded that eGFRcystatinc was a significantly more superior than eGFRcreatinine10.

Benefits of Cystatin C

The Randox cystatin C assay utilises the latex enhanced immunoturbidimetric method offering numerous key features:

A niche product from Randox meaning that Randox are one of the only manufacturers to provide the cystatin C test in an automated biochemistry format

An automated assay which removes the inconvenience and time consumption associated with traditional ELISA testing

Applications are available detailing instrument-specific settings for the convenient use of the Randox cystatin C assay on a wide range of biochemistry analysers

Liquid ready-to-use reagents for convenience and ease-of-use

Latex enhanced immunoturbidimetric method delivering high performance

Extensive measuring range for the detection of clinically important results

Complementary controls and calibrators available offering a complete testing package

Limited interference from Bilirubin, Haemoglobin, Intralipid® and Triglycerides

Cystatin C does not suffer from a ‘blind area’ like creatinine due to cystatin C’s sensitivity to small changes in GFR enabling the early detection renal impairment

An exceptional correlation coefficient of r=1.00 when compared against standard methods

References

[1] Bello, AK, et al. Global Kidney Health Atlas: A report by the Internal Society of Nephrology on the current state of organization and structures for kidney care across the globe. Brussels : Internal Society of Nephrology, 2017.

[2] Bikbov, Boris. Chronic kidney disease: impact on the global burden of mortality and morbidity. The Lancet. [Online] 2015. http://www.thelancet.com/campaigns/kidney/updates/chronic-kidney-disease-impact-on-global-burden-of-mortality-and-morbidity.

[3] National Kidney Foundation. Global Facts: About Kidney Disease. National Kidney Foundation. [Online] National Kidney Foundation, 2015. https://www.kidney.org/kidneydisease/global-facts-about-kidney-disease#_ENREF_1.

[4] Neuen, Brendon Lange, et al. Chronic kidney disease and the global NCDs agenda. s.l. : BMJ Global Health, 2017.

[5] Lascano, Martin E and Poggio, Emilio D. Kidney Function Assessment by Creatinine-Based Estimation Equations. Cleveland Clinic. [Online] August 2010. [Cited: May 16, 2018.] http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/nephrology/kidney-function/.

[6] Swedko, Peter J, et al. Serum Creatinine Is an Inadequate Screening Test for Renal Failure in Elderly Patients. Research Gate. [Online] February 2003. [Cited: May 6, 2018.] https://www.researchgate.net/publication/8243393_Serum_Creatinine_Is_an_Inadequate_Screening_Test_for_Renal_Failure_in_Elderly_Patients.

[7] Mishra, Umashankar. New technique developed to detect chronic kidney disease. Business Line. [Online] May 07, 2018. [Cited: May 17, 2018.] https://www.thehindubusinessline.com/news/science/new-technique-to-detect-chronic-kidney-disease/article23803316.ece.

[8] Chew, Janice SC, et al. Cystatin C-A Paradigm of Evidence Based Laboratory Medicine. NCBI. [Online] May 29, 2008. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533150/.

[9] National Institute for Health and Care Excellence. Chronic kidney disease in adults: assessment and management: 2 Implementation: getting started. NICE. [Online] January 2015. [Cited: April 19, 2018.] https://www.nice.org.uk/guidance/cg182/chapter/implementation-getting-started.

[10] Grubb, Anders. Cystatin C is Indispensable for Evaluation of Kidney Disease. NCBI. [Online] December 28, 2017. [Cited: April 19, 2018.] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746836/.

MORE FEATURED REAGENTS

For more featured reagents click VISIT

Title


Superoxide Dismutase (Ransod)

Superoxide Dismutase (Ransod)

Benefits of the Randox Ransod Assay

Excellent correlation

A correlation coefficient of r=0.965 was displayed when the Randox Ransod assay was compared against commercially available methods.

Excellent precision

The Randox Ransod assay displayed a within run precision of <4.65% CV.

Excellent measuring range

The Randox Ransod assay has a measuring range of 0.00 – 5.50 U/ml for the comfortable detection of clinically important results.

Standard included in kit

The standard is supplied with the Ransod kit, simplifying the ordering process.

Dedicated Ransod control available

A dedicated Ransod control is available offering a complete testing package.

Applications available

Applications available detailing instrument-specific settings for the convenient use of the Randox Ransod assay on a variety of clinical chemistry analysers.

Ordering information

  • Ordering Information

Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

Cat NoSize
SD1255 x 20ml (S)EnquireKit Insert RequestMSDSBuy Online
(S) Indicates standard included in kit
  • PHYSIOLOGICAL SIGNIFICANCE
  • Clinical Significance

Superoxide dismutase (SOD) are a group of metalloenzymes, the first line of defence against reactive oxygen species (ROS)-medicated injury. SOD is responsible for catalysing the dismutation of the superoxide anion free radical (O2) into molecular oxygen and hydrogen peroxide (H2O2). The aim of this process is to reduce the levels of O2 as it damages cells at excessive concentrations 1.

SOD is the most important antioxidant defence against oxidative stress. SOD is a severe anti-inflammatory agent and can prevent precancerous cell changes. Reduced SOD levels have been observed in older generations as SOD levels drop as the body ages and so are more prone to oxidative related diseases. Reduced SOD activity has been identified as having a strong correlation with Alzheimer’s Disease. The overexpression of SOD-2 reduces hippocampal superoxide, preventing memory defects 1. Moreover, SOD has been identified as a potential diagnostic and prognostic marker in patients with gastric cancer 2. SOD has also been linked to other health conditions, including: rheumatoid arthritis, RBC-related disorders, Crohn’s Disease, cystic fibrosis, malignant breast cancer and neuronal apoptosis 1, 3.

Fig. 1. Pathological effects associated with SOD gene mutation or SOD deficiency 4
Pathological effects associated with SOD gene mutation or SOD deficiency - Ransod
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Publications

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    Ransod Control

    Antioxidants Panel

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    Aldolase Assay

    Reagent | Aldolase

    A Myositis Biomarker

    Benefits of the Randox Aldolase Assay

    Exceptional Correlation

    A correlation coefficient of r=0.9917 was displayed when the Randox methodology was compared against commercially available methods.

    Measuring Range

    The Randox Aldolase assay has a measuring range of 1.73 – 106U/l for the comfortable detection of clinically important results.

    Lyophilised Reagents

    Lyophilised reagents offer enhanced stability, reducing wastage.

    Excellent Precision

    The Randox assay displayed a within run precision < 4.47% CV.

    Dedicated Calibrator and Controls Available

    Randox offer a dedicated Aldolase calibrator and controls for a complete testing package.

    Applications Available

    Applications available detailing instrument-specific settings for the convenient use of the Randox Aldolase assay on a variety of clinical chemistry analysers.

    Ordering information

    Cat NoSize
    AD1895 x 20mlEnquireKit Insert RequestMSDSBuy Online

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    Clinical Significance

    Elevated levels of aldolase are detected in myotonic muscular disease, including: polymyositis and progressive muscular dystrophy. Elevated levels of this enzyme have been observed in acute coronary syndromes 1. This enzyme has been identified as a myositis biomarker, a muscle-wasting disease resulting in reduced muscle strength and fatigue 2. Testing this enzyme can be utilised as a marker in the differential diagnosis of muscle weakness as aldolase levels remain consistent where weakness is caused by neurological problems such as multiple sclerosis (MS) 3.

    Physiological Significance

    Aldolase is a glycolytic enzyme responsible for catalysing the conversion of fructose 1-6-diphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate via the glycolysis metabolic pathway. This enzyme is present in all bodily cells, more commonly in the nucleus and cytoplasm. It has been identified as having three isoforms: A, B and C. Isoform A is found bound to the actin-containing filament of the cytoskeleton. By binding (reversible) to these filaments, aldolase aids in regulating cell contractions. The highest concentrations of this enzyme are present in the brain, liver and muscles 1.

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    Anti-Streptolysin O (ASO) Reagent

    Reagent | Anti-Streptolysin O (ASO)

    Key benefits of the Anti-Streptolysin O reagent

    Excellent correlation to standard methods

    The Randox Anti-Streptolysin O assay showed an excellent correlation coefficient of 0.97 compared against other commercially available methods.

     

    Excellent stability

    Stable until expiry date when stored at +2 to +8°C

    Specificity

    The antiserum of Randox Anti-Streptolysin O is monospecific for human ASO and has not been shown to cross react with other serum proteins.

    Liquid ready-to-use

    Available in a liquid ready-to-use format for convenience and ease-of-use.

    Applications available

    Applications available detailing instrument-specific settings for the convenient use of the Randox Anti-Streptolysin O assay on a variety of clinical chemistry analysers.

    Ordering information

    Cat NoSize
    LO3998R1 2 x 9ml (L)
    R2 2 x 14ml
    EnquireKit Insert RequestMSDSBuy Online
    LO8015R1 2 x 8.7ml
    R2 2 x 12ml
    EnquireKit Insert RequestMSDSBuy Online
    LO8305R1 1 x 7.7ml (L)
    R2 1 x 11.2ml
    EnquireKit Insert RequestMSDSBuy Online

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    What is the Anti-Streptolysin O (ASO) assay used for?

    What is Anti-Streptolysin O (ASO)?

    Streptolysin O (SLO) is a toxic and lethal, exocellular immunogenic protein produced and released in response to Group A Streptococcal pyogenes.  For more information on streptococcal infections, please click here [external link].  The release of SLO stimulates the production of Anti-Streptolysin O (ASO) antibodies to neutralise the SLO’s haemolytic effects. The O in the name stands for oxygen-labile.

    What is the Anti-Streptolysin O (ASO) assay used for?

    The Anti-Streptolysin (ASO) test is used to determine recent streptococcal infection and post streptococcal complications which includes rheumatic fever and glomerulonephritis. The presence and level of ASO antibodies in human serum directly reflects the extent and degree of infection. Elevated levels of ASO may also be present in other conditions including scarlet fever, acute rheumatoid arthritis, tonsillitis and various other streptococcal infections as well as in health carriers.

    The Randox Anti-Streptolysin (ASO) assay is used to measure the presence of anti-streptolysin antibodies in the blood to determine if a strep infection is present.

    Specific Protein Panel

    For more information or to visit more reagents within the specific proteins panel, please click here.

    Rapid Tests / Serology Panel

    For more information or to visit more reagents within the rapid tests / serology panel, please click here.


    Antioxidant Reagents

    Why Choose Randox Antioxidants Reagents?

    The Randox range of antioxidant reagents are designed for use within a variety of sectors including clinical, research, veterinary, pharma, food and beverages, cosmetics and sports. Furthermore, our range of antioxidant reagents include routine antioxidant reagents, as well as more specialised tests that are unique to Randox.

    Download our Antioxidants Brochure

    Randox Antioxidant Reagents Benefits

    • Suitable for automation which removes the inconvenience and time consumption associated with traditional ELISA based testing options
    • Instrument Specific Applications (ISA’s) are available for an extensive range of clinical chemistry analysers which includes detailed instrument specific settings for increased convenience.
    • Suitable for a wide variety of sample types, including whole blood (human and animal), serum, plasma, erythrocytes, among others
    • Randox antioxidants are available in liquid and lyophilised formats
    • Suitable for automation which removes the inconvenience and time consumption associated with traditional ELISA based testing options
    • A variety of kits, methods and ranges are available

    The role of antioxidant reagents

    Antioxidants are important for the body’s immune system to protect the body against free radical attacks. Randox provides a range of antioxidant reagents to assess all three levels of the body’s defence system (preventative antioxidants, scavenging antioxidants and repair enzymes).

    Preventative antioxidants – inhibit the formation of free radicals including metal binding proteins like; Ceruloplasmin, Metallothionine, Albumin, Transferrin, Ferritin and Myoglobin.

    Repair enzymes – repair damaged biomolecules such as DNA repair enzymes.

    Scavenging antioxidants – remove any reactive species once formed such as Superoxide Dismutase, Glutathione Peroxidase, Catalase and small molecules including Ascorbate, Tocopherol, Bilirubin, Uric Acid, Carotenoids and Flavonoids.

    Antioxidant benefits against disease

    Free radicals have been found to play a role in the development of many diseases including cancer (free radicals are thought to promote cell transformation into a cancer cell), arthritis and inflammatory diseases (increased oxidative stress in rheumatoid arthritis patients suggests antioxidants could have an important role), cardiovascular disease (antioxidants have been found to improve cardiac health), and Alzheimer’s disease (antioxidants have a role in removing deleterious free radicals from the brain).

    Email Us

    Get in touch with Randox via email at reagents@randox.com

    Need Instructions?

    Kit Inserts are available to download for free on our online portal

    Buy Online

    Order your lipid kits today by visiting our online store 


    Amylase Reagent

    Reagent | Amylase

    Key Benefits of the Randox Amylase reagent

    Excellent stability – Stable to expiry when stored at +2 to +8°C

    Methodology – Ethylidene PNPG7 method

    Liquid ready-to-use reagents – The Randox reagent comes in a liquid ready-to-use format which is more convenient as the reagent does not need to be reconstituted which aids in reducing the risk of errors occurring

    Ordering information

    Cat NoSize
    AY3805R1 4 x 16ml (L)
    R2 4 x 5ml (L)
    EnquireKit Insert RequestMSDSBuy Online
    AY7931R1 6 x 50ml (L)
    R2 4 x 18ml
    EnquireKit Insert RequestMSDSBuy Online
    AY8004R1 7 x 18ml (L)
    R2 7 x 7.3ml
    EnquireKit Insert RequestMSDSBuy Online
    AY8335R1 4 x 20ml (L)
    R2 4 x 7ml
    EnquireKit Insert RequestMSDSBuy Online
    (L) Indicates liquid option

    Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers.  Contact us to enquire about your specific analyser.

    What is Amylase used for?

    It is a digestive enzyme / special protein produced by the pancreas and salivary glands.  Salivary amylase is responsible for breaking down starch in the mouth and converting it into maltose.  Pancreatic amylase passes through a duct from the pancreas to the small intestine where the digestive process is completed through converting starch into glucose.  The glucose is then absorbed into the blood and carried throughout the body.

    Damage or inflammation to the pancreas can result in under / over production of amylase which can be a sign of pancreatic disorder which includes pancreatic pseudocyst, pancreatic abscess, pancreatic cancer, gallbladder disease, mumps or ectopic pregnancy.  For more information on pancreatic cancer, please click here. The Randox assay is used for the quantitative in vitro determination of amylase activity in serum, urine and plasma.


    Lipase Reagent

    Reagent | Lipase

    Key Benefits of the Randox Lipase Assay

    Excellent precision

    The Randox lipase assay displayed a precision of  <5% CV.

    Exceptional correlation

    The Randox lipase assay displayed an exceptional co