Molecular QC and EQA for Infectious Disease Testing

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Molecular QC and EQA for Infectious Disease Testing

Molecular EQA / QC for Infectious Disease Testing

Earlier this year, Randox entered into a strategic partnership, bringing on-board Qnostics Molecular Controls and QCMD Molecular EQA which comprises hundreds of controls and EQA programmes for molecular infectious disease testing.

Background

The Global Molecular Diagnostics market is estimated to be worth 6.54 billion USD. This market is classified into infectious diseases, oncology, genetic tests and blood screening. Infectious diseases account for the largest share of the global market.

According to the World Health Organisation (WHO), Infectious Diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi. These diseases can be spread – directly or indirectly – from one person to another.

Qnostics - Molecular Controls

Designed to meet the demands of today’s molecular diagnostics laboratory and laboratories carrying out Nucleic Acid Testing (NAT), the Qnostics range comprises hundreds of characterised viral, bacterial and fungal targets covering a wide range of Transplant Associated Diseased, Respiratory Diseases, Blood Borne Viruses, Sexually Transmitted Infections, Gastro-Intestinal Diseases and Central Nervous System Diseases.

Qnostics products can be used in the daily monitoring of assay performance, linearity assessment, assay evaluation, validation/verification of new assays and staff training.

There are five main product areas for Qnostics:

  • Product Groups (click to expand)

    Q Controls
    Independently manufactured, this range of positive run, whole pathogen, third party controls are designed to monitor the daily performance of a wide of range molecular assays used in the detection of infectious diseases. These controls help in supporting a laboratory’s accreditation requirements, in line with ISO 15189:2012.

    Analytical Q Panels
    Designed to cover the dynamic range of an assay, Analytical Q Panels allow assessment of an assays linearity, LOD and LOQ. Each panel contains a minimum of five samples, including a negative that spans the dynamic range of the assay in a linear progression.

    Molecular Q Panels
    Consisting of three levels (high, medium and low), Molecular Q Panels are intended to evaluate an assays analytical measuring range.  Molecular Q Panels can also be used to support training of laboratory staff and in the development of molecular diagnostic assays.

    Evaluation Panels
    Evaluation Panels cover a range of genotypes and may be used to evaluate assay characteristics, confirm performance claims and ultimately ensure the assay is fit for purpose. Evaluation Panels may also be used in the validation of molecular assays and development of new molecular diagnostic assays.

    QCMD Past Panels
    Available for use in assay evaluation and staff training, EQA samples are available from past QCMD challenges.

    Custom Manufacture

    Qnostics are specialists in the custom manufacture of quality control materials for use in the detection of infectious diseases using molecular based methods. Qnostics will work with you to develop a bespoke solution designed specifically to meet the individual and unique requirements of your lab.

    • Choose from hundreds of molecular characterised targets
    • Targets can be custom made into numerous different formats
    • The whole pathogen format accurately mimics clinical samples
    • All materials can be provided in a “ready-to-use” or liquid frozen format

    Qnostics custom made Molecular Infectious Disease Controls are designed to fit all stages of your assays product life cycle from product development to launch.

QCMD – Molecular External Quality Control

QCMD is a world leading External Quality Assessment (EQA) / Proficiency Testing (PT) scheme, dedicated to improving the quality of molecular diagnostic assays used in the detection of infectious diseases.

With an extensive database of over 2000 participants in over 100 countries, QCMD is one of the largest providers of molecular EQA in the field of infectious disease testing.

EQA participants receive an individual report outlining their performance relative to their method and technology groups. A supplementary report may be commissioned – this includes any additional relevant information regarding the annual EQA distribution, as well as scientific expert commentary and feedback on the overall results within that distribution.

  • Features & Benefits (click to expand)

    Frequency

    A variety of programme options are available. Choose the number of challenges that best suit your laboratory’s requirements.

    Online EQA Management System

    ITEMS provides an online tool to easily manage all EQA activities from programme registration to submission of results and provision of EQA reports. Different levels of user access are available so data can be accessed by whoever needs it.

    High level of participation

    Over 2000 participants in more than 100 countries ensuring peer group numbers are maximised.

    Comprehensive reports

    Receive individual reports for each challenge and a final supplementary report at the end of the cycle visual assessment of performance.

    International accreditation

    Programmes are accredited to ISO 17043.

Continue Reading

Qnostics

Contact Us


Randox Biosciences: dedicated to advancing scientific discovery

Randox Laboratories is an international clinical diagnostic solutions company with over 35 years’ experience in the industry. Randox is a global market leader, providing revolutionary products for laboratories worldwide and is dedicated to improving health.

Randox Biosciences is part of Randox Laboratories and is dedicated to advancing scientific discovery, drug development and diagnostics. Spanning four key divisions; Life Sciences, Pharma Sciences, Research and Molecular; Randox Biosciences offers complete tailored solutions for clinical and research use.

From initial cultivation of raw materials for assay development, through to providing companion diagnostics, custom and molecular based assays across a range of therapy areas; Randox Biosciences is a trusted partner supplying quality diagnostic solutions to the clinical, life science, pharmaceutical, research and biopharma industries. We specialise in supplying academic centres, genetics laboratories and the global biopharmaceutical industry with products tailored to their specific needs.

Randox Biosciences Research team encompasses a knowledgeable group of who are dedicated to assisting your research project to completion. Recently, the research team has expanded to include Business Development Executives in America to support academic centres of excellence achieve their potential while utilising our quality products. We are proud to welcome Rebecca Newburg who will be focusing her efforts on the US-Midwest market and Celestine Eshiet who will be working on the US -West Coast.

We cover five areas of research such as Sport and Exercise, Cardiovascular, Metabolic, Immunology and Oncology. These five areas include our Metabolic Syndrome Array 1 & 2, Cytokine Arrays and Cardiac Array including CK-MB, H-FABP, Myoglobin and Troponin.

 

If you work in an academic centre and are interested in our variety of arrays, analysers whether that be chemistry or immunoassay analysers, or our reagents or quality control please do not hesitate to contact us at info@randoxbiosciences.com.

 

 

 

 

 

 

 

 


Product Spotlight: Molecular QC and EQA for Infectious Disease Testing

Molecular QC and EQA for Infectious Disease Testing

Earlier in the year, Randox entered into a strategic partnership, bringing on-board Qnostics Molecular Controls and QCMD Molecular EQA which comprises hundreds of controls and EQA programmes for molecular infectious disease testing.

Background

The Global Molecular Diagnostics market is estimated to be worth 6.54 billion USD. This market is classified into infectious diseases, oncology, genetic tests and blood screening. Infectious diseases account for the largest share of the global market.

According to the World Health Organisation (WHO), Infectious Diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi. These diseases can be spread – directly or indirectly – from one person to another.

Qnostics - Molecular Controls

Designed to meet the demands of today’s molecular diagnostics laboratory and laboratories carrying out Nucleic Acid Testing (NAT), the Qnostics range comprises hundreds of characterised viral, bacterial and fungal targets covering a wide range of Transplant Associated Diseased, Respiratory Diseases, Blood Borne Viruses, Sexually Transmitted Infections, Gastro-Intestinal Diseases and Central Nervous System Diseases.

Qnostics products can be used in the daily monitoring of assay performance, linearity assessment, assay evaluation, validation/verification of new assays and staff training.

There are five main product areas for Qnostics:

  • Product Groups (click to expand)

    Q Controls
    Independently manufactured, this range of positive run, whole pathogen, third party controls are designed to monitor the daily performance of a wide of range molecular assays used in the detection of infectious diseases. These controls help in supporting a laboratory’s accreditation requirements, in line with ISO 15189:2012.

    Analytical Q Panels
    Designed to cover the dynamic range of an assay, Analytical Q Panels allow assessment of an assays linearity, LOD and LOQ. Each panel contains a minimum of five samples, including a negative that spans the dynamic range of the assay in a linear progression.

    Molecular Q Panels
    Consisting of three levels (high, medium and low), Molecular Q Panels are intended to evaluate an assays analytical measuring range.  Molecular Q Panels can also be used to support training of laboratory staff and in the development of molecular diagnostic assays.

    Evaluation Panels
    Evaluation Panels cover a range of genotypes and may be used to evaluate assay characteristics, confirm performance claims and ultimately ensure the assay is fit for purpose. Evaluation Panels may also be used in the validation of molecular assays and development of new molecular diagnostic assays.

    QCMD Past Panels
    Available for use in assay evaluation and staff training, EQA samples are available from past QCMD challenges.

    Custom Manufacture

    Qnostics are specialists in the custom manufacture of quality control materials for use in the detection of infectious diseases using molecular based methods. Qnostics will work with you to develop a bespoke solution designed specifically to meet the individual and unique requirements of your lab.

    • Choose from hundreds of molecular characterised targets
    • Targets can be custom made into numerous different formats
    • The whole pathogen format accurately mimics clinical samples
    • All materials can be provided in a “ready-to-use” or liquid frozen format

    Qnostics custom made Molecular Infectious Disease Controls are designed to fit all stages of your assays product life cycle from product development to launch.

QCMD – Molecular External Quality Control

QCMD is a world leading External Quality Assessment (EQA) / Proficiency Testing (PT) scheme, dedicated to improving the quality of molecular diagnostic assays used in the detection of infectious diseases.

With an extensive database of over 2000 participants in over 100 countries, QCMD is one of the largest providers of molecular EQA in the field of infectious disease testing.

EQA participants receive an individual report outlining their performance relative to their method and technology groups. A supplementary report may be commissioned – this includes any additional relevant information regarding the annual EQA distribution, as well as scientific expert commentary and feedback on the overall results within that distribution.

  • Features & Benefits (click to expand)

    Frequency

    A variety of programme options are available. Choose the number of challenges that best suit your laboratory’s requirements.

    Online EQA Management System

    ITEMS provides an online tool to easily manage all EQA activities from programme registration to submission of results and provision of EQA reports. Different levels of user access are available so data can be accessed by whoever needs it.

    High level of participation

    Over 2000 participants in more than 100 countries ensuring peer group numbers are maximised.

    Comprehensive reports

    Receive individual reports for each challenge and a final supplementary report at the end of the cycle visual assessment of performance.

    International accreditation

    Programmes are accredited to ISO 17043.

Continue Reading

Qnostics

Contact Us

Product Spotlight Home

Visit the Product spotlight Home to see past product spotlights


Study by Center for Disease Dynamics finds dramatic rise in global antibiotic consumption

A dramatic increase in global consumption of antibiotics has led public health experts to call for innovative new ways to rein in excessive use of the drugs, following a study by the Centre for Disease Dynamics, Economics and Policy, in Washington DC.

The study found a 65% rise in worldwide consumption of antibiotics from 2000 to 2015, despite efforts to encourage more prudent use of the drugs. The unrestrained use of antibiotics is the main cause of the increasing appearance of drug-resistant infections, which now kill more than half a million people worldwide. A report in 2014 predicted that the spread of drug resistance could claim millions of lives per year by 2050.

Eili Klein, an author of the study, which was published in Proceedings of the National Academy of Science, criticised the global response to the global antibiotic resistance crisis as “slow and inadequate” and called for a “radical thinking” of antibiotic consumption.

At Randox, our pioneering R&D teams have developed a revolutionary swab test for respiratory infections which will help to reduce the unnecessary prescription of antibiotics. Earlier this year, Public Health England reported that 59% of people who visited their GP with a sore throat were prescribed antibiotics, in spite of only 13% actually needing them.

The new Randox swab test indicates the cause of the infection and whether a patient needs antibiotics or not, by rapidly detecting and identifying the cause of 21 respiratory infections in just 5 hours

The test assists the clinician in prescribing the appropriate antibiotic.

John Lamont, Lead Scientist at Randox Laboratories, said;

“Current diagnostic testing for respiratory infections takes at least 36 hours to confirm the nature of an infection, and they cannot name and categorise infections as bacterial or viral in the way our new respiratory test can.”

This test, if widely adopted, could allow medical practitioners to make the correct treatment choice on the same day as examination and before patients have already begun a precautionary course of inefficient antibiotics. It would also have additional efficiency savings for the NHS, by eliminating the need for lengthy microbiology lab tests and unnecessarily prescribing drugs which are not needed.

This new rapid and accurate test will give clinicians confidence in their diagnosis of respiratory infections and will allow for quicker treatment if necessary, which benefits patient outcomes. By reducing the prescription of unnecessary antibiotics, we can limit their use only for when they are truly needed.

The test is also available as a Randox Health Cough, Cold & Flu offering, and can be carried out by booking an appointment with Randox Health at our clinics in Crumlin, Holywood or London, or by arranging the mobile clinic to visit you at your home or place of work.

Book an appointment with one of our clinics, or arrange the mobile clinic, by phoning 0800 2545 130 or by clicking here.

For further information about the Randox Respiratory Infection Array please contact the Randox PR team by email: randoxpr@randox.com or phone 028 9442 2413

 

 

 


Randox Biosciences: dedicated to advancing scientific discovery

Randox Laboratories is an international clinical diagnostic solutions company with over 35 years’ experience in the industry. Randox is a global market leader, providing revolutionary products for laboratories worldwide and is dedicated to improving health.

Randox Biosciences is part of Randox Laboratories and is dedicated to advancing scientific discovery, drug development and diagnostics. Spanning four key divisions; Life Sciences, Pharma Sciences, Research and Molecular; Randox Biosciences offers complete tailored solutions for clinical and research use.

From initial cultivation of raw materials for assay development, through to providing companion diagnostics, custom and molecular based assays across a range of therapy areas; Randox Biosciences is a trusted partner supplying quality diagnostic solutions to the clinical, life science, pharmaceutical, research and biopharma industries. We specialise in supplying academic centres, genetics laboratories and the global biopharmaceutical industry with products tailored to their specific needs.

Randox Biosciences Research team encompasses a knowledgeable group of who are dedicated to assisting your research project to completion. Recently, the research team has expanded to include Business Development Executives in America to support academic centres of excellence achieve their potential while utilising our quality products. We are proud to welcome Rebecca Newburg who will be focusing her efforts on the US-Midwest market and Celestine Eshiet who will be working on the US -West Coast.

We cover five areas of research such as Sport and Exercise, Cardiovascular, Metabolic, Immunology and Oncology. These five areas include our Metabolic Syndrome Array 1 & 2, Cytokine Arrays and Cardiac Array including CK-MB, H-FABP, Myoglobin and Troponin.

 

If you work in an academic centre and are interested in our variety of arrays, analysers whether that be chemistry or immunoassay analysers, or our reagents or quality control please do not hesitate to contact us at info@randoxbiosciences.com.

 

 

 

 

 

 

 

 


Randox Laboratories and Qnostics announce strategic partnership

Randox Laboratories and Qnostics have today announced that they have entered into a strategic partnership.  The partnership will provide Randox Laboratories with access to the Qnostics molecular range of products for sales and distribution purposes, complementing the established Randox Laboratories portfolio.

Access to the Randox Laboratories commercial capabilities will enhance Qnostics’ market penetration, whilst also maintaining their presence as an independent provider of molecular quality controls and custom services.

MD of Randox Laboratories, Dr Peter FitzGerald said;

“We are delighted to have agreed a strategic partnership with Qnostics, an arrangement we see as mutually beneficial.  We look forward to working together to strengthen the molecular service we provide to our global markets whilst enhancing the Qnostic brand and market penetration.”

Dr Frank Opdam, Head of Commercial of Qnostics said;

“We believe this is an ideal partnership. We look forward to working with Randox Laboratories and the growth that will result from the global access this partnership will provide to Qnostics for its expanding range of molecular quality control products.”

For further information please contact the Randox PR Team: phone 028 9442 2413 or email randoxpr@randox.com 


GPs are told to stop prescribing antibiotics for sore throats

Today, the National Institute for Health and Care Excellence has published guidelines that state doctors should not prescribe precious antibiotics for most people with sore throats and should instead recommend drugs like paracetamol.

The guidelines from NICE and Public Health England, which aim to limit the use of antibiotics, said doctors should only be prescribing the medicines for more severe cases that are most likely to have been caused by a bacterial infection.

This is despite recent research that suggests antibiotics are prescribed in 60% of sore throat cases, for which doctors are unable to tell if the infection is viral or bacterial.

The National Institute for Health and Care Excellence said most sore throats were caused by viral infections, which cannot be treated by antibiotics.

At Randox, our pioneering R&D teams have developed a revolutionary swab test for respiratory infections which indicates the cause of the infection and whether a patient needs antibiotics or not. This helps to limit the number of patients who are prescribed antibiotics unnecessarily.

The Randox test, which can rapidly detect and identify the cause of 21 respiratory infections in just 5 hours, assists the clinician in prescribing the appropriate antibiotic.

John Lamont, Lead Scientist at Randox Laboratories, said;

“Current diagnostic testing for respiratory infections takes at least 36 hours to confirm the nature of an infection, and they cannot name and categorise infections as bacterial or viral in the way our new respiratory test can.”

This test, if widely adopted, could allow medical practitioners to make the correct treatment choice on the same day as examination and before patients have already begun a precautionary course of inefficient antibiotics.  It would also have additional efficiency savings for the NHS, by eliminating the need for lengthy microbiology lab tests and unnecessarily prescribing drugs which are not needed.

This new rapid and accurate test will give clinicians confidence in their diagnosis of respiratory infections and will allow for quicker treatment if necessary, which benefits patient outcomes.

The test is also available as a Randox Health Cough, Cold & Flu offering, and can be carried out by booking an appointment with Randox Health at our clinics in Crumlin, Holywood or London, or by arranging the mobile clinic to visit you at your home or place of work.

Find out more about the Cough, Cold & Flu Respiratory test here.

Book an appointment with one of our clinics, or arrange the mobile clinic, by phoning 0800 2545 130 or by clicking here.

For further information please contact the Randox PR team by email: randoxpr@randox.com or phone 028 9442 2413

 


Evidence Investigator | Adaptable, Efficient & Comprehensive

The Evidence Investigator is a compact, semi-automated benchtop analyser that offers efficient and comprehensive testing across a range of applications including clinical diagnostics, molecular, research, toxicology and food diagnostics.

Renowned for its versatility, robustness and effective reporting methods, the Evidence Investigator has been used in a wide range of laboratory settings for over 15 years. This highly advanced yet simple to use analyser has only one moving part, giving the user peace of mind.

The Evidence Investigator contains a host of innovative on-board data analysis features ensuring manual processes are kept to a minimum.

By utilising the same multiplex technology as the other Evidence Series analysers, the Evidence Investigator can process up to 44 results from a single sample, with a maximum throughput of up to 2376 tests per hour. Offering efficiency without compromising on accuracy, the Evidence Investigator is the perfect fit for medium throughput laboratories seeking maximum use of bench space.

Accurate and Robust

Like all the Evidence Series analysers, what sets it apart is technology. The Evidence Investigator is extremely well equipped to provide reliable results, while simultaneously robust enough to withstand frequent, heavy use.

Results are generated using a Charge Coupled Device (CCD) camera, which quantifies chemiluminescent light. This light measures the degree of binding between the patient sample and specific biochip bound ligands, generating highly accurate and reliable results.

Consolidation

The Evidence Investigator is the world’s first platform allowing consolidation of immunoassay and molecular diagnostics. This is achieved through utilising protein and DNA based biochips. By giving the user the ability to consolidate tests, the Evidence Investigator improves laboratory efficiency and reduces costs.

 Advanced Reporting

The Evidence Investigator image processing software translates light signal generated from chemiluminescent reactions into analyte concentration. This removes the need for any manual processing of data.

Previously unreported tests can also be retrieved, so they can be tested retrospectively. This saves time, labour costs and reduces any reagents wastage. All data is then analysed on-board, removing issues related to human error and result manipulation.

About the Randox Evidence Series

The Evidence Series is set to revolutionise diagnostic testing forever. Offering unrivalled capabilities across all analysers, we truly believe that the Evidence Series range of immunoassay analysers can meet your diagnostic testing capabilities.

For more information on the Evidence Investigator, or any of the Evidence Series analysers, visit https://www.randox.com/evidence-series/ or contact us evidenceseries@randox.com.

 


Molecular Diagnostics from Randox Biosciences

Our Randox Biosciences division is a trusted partner in supplying quality diagnostic solutions to the Clinical, Life Science, Pharmaceutical, Research and BioPharma industries.

Our molecular product range offers diagnostic, prognostic and predictive solutions across a variety of disease areas including sexually transmitted infections (STI), respiratory tract infection, colorectal cancer, familial hypercholesterolemia (FH) and cardiovascular disease (CVD).

Additionally, we can provide a wide range of assay formats including single nucleotide polymorphisms (SNP) genotyping, pathogen detection and mutation detection. The arrays are optimised for use with the Randox Evidence Investigator semi-automated, medium throughput bench-top biochip analyser.

One test, 10 results.

Our STI multiplex array II simultaneously detects 10 bacterial, viral and protozoan infections including primary, secondary and asymptomatic co-infections for a complete infection profile. The assay is based on a combination of multiplex, PCR and biochip array hybridisation. Innovative PCR priming technology permits high discrimination between multiple targets. A unique primer set is designed for each target which will hybridise to a complimentary oligo-nucleotide probe spotted on a biochip discrete test region (DTR).

The combination of priming and spatially organised biochip array technology enables enhanced specificity of the assay. Analysis can be completed from template DNA through PCR to data readout in less than 6 hours. The array is validated for urine and swab sample matrices with up to 53 patient samples being processed simultaneously. The array is CE marked for routine clinical use.

Our STI Multiplex Array II includes tests for the following STIs;

Neisseria Gonnorrhoea (NG)                                       Mycoplasma Genitalium (MG)

Ureaplasma Urealyticum (UU)                                    Chlamydia Trachhomatis (CT)

Tricomonas Vaginalis (TV)                                            Haemophilus Ducreyi (HD)

Mycoplasma Hominis (MH)                                          Treponema Pallidum (TP)

Herpes Simplex virus I (HSV-1)                                   Herpes Simplex Virus 2 (HSV-2)

Randox Biosciences also offer four additional Molecular arrays.

For more information on our Molecular arrays please contact us by sending an email to Info@randoxbiosciences.com

 

 


Evidence Series Immunoanalysers

 

Powered by Biochip Array Technology

In 2002, Randox invented a world first, Biochip Array Technology (BAT), instantly changing the landscape of diagnostic testing forever. BAT is a multi-analyte platform which provides an unrivaled increase in patient information per sample. Instead of a patient sample needing to be subdivided for each test result, or in some cases re-collected, Biochip Array Technology offers a diagnostic patient profile with each patient sample. So now the patient’s needs become the focus, as BAT delivers the multiple results needed for improved diagnosis.

With over £250 million invested into Biochip Array Technology research and development, Randox have launched a range of Biochip Array Technology immunoanalysers – The Evidence Series. This includes the Evidence, the Evidence Investigator and the Evidence MultiSTAT. Each analyser is developed with boundary pushing engineering, designed to make financial, labour and time savings for the end user. Utilising this technology, the Evidence series guarantees cost-effective, highly accurate and flexible testing solutions.

Click on the immunoanalysers below for more information

Evidence Investigator

Evidence MultiSTAT

Evidence

Why choose the Evidence Series?

  • Biochip Array Technology has a proven high standard of precise test results with CVs <10%
  • Multiplex testing reduces the amount of time and labour spent on individual tests and associated laboratory costs
  • Simultaneous testing represents greater value for money as fewer patient samples are able to deliver more in-depth analysis
  • Testing for multiple markers simultaneously increases the amount of patient information rapidly available to the clinician, allowing for more informed diagnosis
  • Randox has the world's most innovative test development program, ensuring that with Biochip Array Technology you are able to offer improved options from your laboratory
  • Multiple sample types can be used on one immunoanalyser including serum, plasma, whole blood, urine and oral fluid
  • Vast Biochip Array Technology test menu allows clinicians to detect routine and novel markers for advanced analysis
  • Through utilising a smaller sample volume, more assays can be run without needing further collections

Biochip Array Technology Test Menu

Adhesion Molecules
E-Selectin P-Selectin L-Selectin
Intercellular Adhesion Molecule-I – ICAM-I Vascular Cell Adhesion Molecule-I –VCAM-I
Alzheimer’s
Apolipoprotein E4 –ApoE4 Pan Apolipoprotein E – Apo E
Anaemia
Ferritin Folate Vitamin B12
Bone Disease
Vitamin D
Cancer
Carcinoembryonic Antigen – CEA Free Prostate Specific Antigen − FPSA Total Prostate Specific Antigen − TPSA
Cardiac
Cardiac Troponin I – cTnl Creatine Kinase MB – CKMB Heart Fatty Acid Binding Protein – H-FABP Myoglobin
Cerebral
Brain-Derived Neurotrophic Factor − BDNF Neuron Specific Enolase − NSE
Cytokines
Epidermal Growth Factor − EGF Granulocyte Macrophage Colony Stimulating Factor Interferon-γ − IFN-γ Interleukin-1 alpha − IL-1α
Interleukin-1 beta − IL-1β Interleukin-2 − IL-2 Interleukin-3 − IL-3 Interleukin-4 − IL-4
Interleukin-5 − IL 5 Interleukin-6 − IL-6 Interleukin-7 − IL-7 Interleukin-8 − IL-8
Interleukin-4 − IL-4 Interleukin-5 − IL 5 Interleukin-6 − IL-6 Interleukin-7 − IL-7
Interleukin-8 − IL-8 Interleukin-10 − IL-10 Interleukin-12p70 − IL-12p70 Interleukin-13 − IL-13
Interleukin-15 − IL 15 Interleukin-23 − IL-23 Macrophage Infl ammatory Protein-1α − MIP-1α Matrix Metalloproteinase 9 − MMP 9
Monocyte Chemotactic Protein-1 − MCP-1 Soluble IL-2 Receptor Alpha − sIL-2Rα Soluble IL-6 Receptor − sIL-6R Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1
Soluble Tumour Necrosis Factor Receptor 2 − sTNFR2 Tumour Necrosis Factor-α − TNF-α Vascular Endothelial Growth Factor − VEGF
Diabetes
Insulin
Endocrine
Cortisol Dehydroepiandrosterone-Sulphate- DHEAS
Fertility / Pregnancy
Estradiol Follicle Stimulating Hormone − FSH Luteinizing Hormone − LH Progesterone
Prolactin Sex Hormone Binding Globulin − SHBG Testosterone
Fibrinolysis
D-Dimer
Gastro
Gastrin 17 – GI7 Helicobacter pylori – H. pylori Pepsinogen I – PGI Pepsinogen II – PGII
Metabolic
Adiponectin Ferritin Insulin Leptin
Plasminogen Activator Inhibitor − PAI-1 Resistin
Renal
Adiponectin Complement C3a des Arginine – C3a des Arg CRP (C-Reactive Protein) Cystatin C
D-Dimer Epidermal Growth Factor − EGF Fatty Acid Binding Protein-1 − FABP1 Interleukin-8 − IL-8
Macrophage Infl ammatory Protein-1α − MIP-1α Neutrophil Gelatinase – Associated Lipocalin – NGAL Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1 Soluble Tumour Necrosis Factor Receptor 2 − sTNFR2
Stroke
Brain-Derived Neurotrophic Factor − BDNF D-Dimer Glial Fibrillary Acidic Protein − GFAP Glutathione S – Transferase Pi – GSTPi
Heart Fatty Acid Binding Protein – H-FABP Interleukin-6 − IL-6 Nucleoside Diphosphate Kinase – NDKA Neuron Specifi c Enolase − NSE
Parkinson Protein 7 − PARK-7 Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1
Thyroid
Anti-Thyroglobulin − Anti-Tg Anti-Thyroid Peroxidase − Anti-TPO Free Tri-iodothyronine − FT3 Free Thyroxine − FT4
Thyroid Stimulating Hormone − TSH Thyroxine Binding Globulin − TBG Total Tri-iodothyronine − TT3 Total Thyroxine − TT4
Toxicology
Amphetamine Barbiturates Benzodiazepines I Benzodiazepines II
Buprenorphine Cannabinoids – THC Cocaine Metabolite Dextromethorphan
Fentanyl Ketamine Meprobamate Methadone
Opiate Oxycodone I Oxycodone II Phencyclidine – PCP
Tramadol Tricyclic Antidepressants Zolpidem
Molecular
20 SNPs Adenovirus A/B/C/D/E APOB – 1 mutation Bordetella pertussis
BRAF – 1 mutation Chlamydia trachomatis – (CT) Chlamydophila pneumoniae Coronavirus 229E/NL63
Coronavirus OC43/HKU1 Enterovirus A/B/C Haemophilus ducreyi – (HD) Haemophilus influenzae
Herpes simplex Virus 1– (HSV-1) Herpes simplex Virus 2 – (HSV-2) Human Bocavirus 1/2/3 Human Metapneumovirus – hMPV
Influenza A/B KRAS – 16 mutations LDLR – 38 mutations Legionella pneumophila
Moraxella catarrhalis Mycoplasma genitalium – (MG) Mycoplasma hominis – (MH) Mycoplasma pneumoniae
Neisseria gonorrhoea – (NG) Parainfluenza Virus 1/2/3/4 PCSK9 – 1 mutation PIK3CA – 3 mutations
Respiratory Syncytial Virus a – RSVa Respiratory Syncytial Virus b – RSVb Rhinovirus A/B Streptococcus pneumoniae
Treponema pallidum – (TP) Trichomonas vaginalis – (TV) Ureaplasma urealyticum – (UU)
Veterinary Residues / Food Diagnostics
17β-Clostebol 5-hydroxy Flunixin Aflatoxin B1 Aflatoxin G1/G2
Aflatoxin M1 AHD Amikacin/Kanamycin Amino Benzimidazoles
Amoxicillin AMOZ Amphenicols Ampicillin
AOZ Apramycin Avermectins Bacitracin
Baquiloprim Benzimidazoles Beta-agonists Beta-Lactams
Boldenone Cefapirin Cefoperazone Cefquinome
Ceftiofur Cefuroxime Cephalexin Cephalonium
Chloramphenicol Chlormadinone Clopidol Cloxacillin
Corticosteroids Dapsone Decoquinate Deoxynivalenol
Dexamethasone Diacetoxyscirpenol Diclazuril Dicloxacillin
Dihydrostreptomycin Ergot Alkaloids Erythromycin Ethinylestradiol
Fumonisins Gentamicin Gestagens Halofugine
Hygromycin B Imidocarb Kanamycin Lasalocid
Levamisole Lincomycin Lincosamides MaduramicinG
Melamine Meloxicam Metamizole Methyltestosterone
Monensin Moxidectin (MXD) Nandrolone Neomycin/Paromomycin
Nicarbazin Nitroimidazoles Nitroxynil Novobiocin
Ochratoxin A Oxacillin Paxilline Penicillin G
Penicillin V Phenylbutazone Pirlimycin Polymixins
Quinolones Ractopamine Rifaximin Robenidine
Salinomycin SEM Spectinomycin Spiramycin
Spiramycin/Josamycin Stanozolol Stilbenes Streptomycin
Sulfaguanidine Sulfamethazine Sulphachlorpyridazine Sulphadiazine
Sulphadimethoxine Sulphadoxine Sulphamerazine Sulphamethazine
Sulphamethizole Sulphamethoxazole Sulphamethoxypyridazine Sulphapyridine
Sulphaquinoxaline Sulphathiazole Sulphisoxazole Sulphonamides
T2 toxin Tetracyclines Thiabendazole Thiamphenicol
Tobramycin Tolfenamic Acid Toltrazuril Trenbolone
Triclabendazole Trimethoprim Tylosin Tylosin B/Tilmicosin
Virginiamycin Virginiamycin M1 Zearalenone Zeranol

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